S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold
S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold
S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold
S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold

Compare Stocks

Comparative Price Performance Over Time

Compare Stocks - Price & Volume

CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Amicus Therapeutics, Inc. stock logo
FOLD
Amicus Therapeutics
$10.61
+2.7%
$12.18
$9.70
$14.57
$3.13B0.753.00 million shs2.50 million shs
Insmed Incorporated stock logo
INSM
Insmed
$24.32
-1.9%
$27.45
$17.41
$32.00
$3.61B0.921.74 million shs5.53 million shs
Prestige Consumer Healthcare Inc. stock logo
PBH
Prestige Consumer Healthcare
$69.67
+1.9%
$70.70
$55.96
$75.31
$3.46B0.52239,816 shs454,206 shs
Pacira BioSciences, Inc. stock logo
PCRX
Pacira BioSciences
$26.25
+0.6%
$29.04
$25.76
$48.60
$1.22B0.76497,717 shs448,972 shs
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
$13.33
+2.2%
$19.85
$10.92
$59.99
$801.27M0.861.01 million shs1.26 million shs
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Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Amicus Therapeutics, Inc. stock logo
FOLD
Amicus Therapeutics
+2.71%-0.66%-11.58%-11.80%-9.16%
Insmed Incorporated stock logo
INSM
Insmed
-1.94%-10.75%-8.50%-13.14%+35.87%
Prestige Consumer Healthcare Inc. stock logo
PBH
Prestige Consumer Healthcare
+1.91%+2.14%-5.09%+17.03%+13.01%
Pacira BioSciences, Inc. stock logo
PCRX
Pacira BioSciences
+0.57%-2.16%-12.56%-17.56%-42.18%
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
+2.26%-13.67%-32.27%-48.75%-71.90%

MarketRank™

CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Amicus Therapeutics, Inc. stock logo
FOLD
Amicus Therapeutics
3.7314 of 5 stars
3.50.00.04.32.10.81.9
Insmed Incorporated stock logo
INSM
Insmed
3.5715 of 5 stars
4.51.00.04.50.60.00.6
Prestige Consumer Healthcare Inc. stock logo
PBH
Prestige Consumer Healthcare
3.8141 of 5 stars
3.34.00.83.50.02.50.6
Pacira BioSciences, Inc. stock logo
PCRX
Pacira BioSciences
4.9615 of 5 stars
4.53.00.03.93.02.53.1
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
3.9518 of 5 stars
4.11.00.04.32.11.70.6

Analyst Ratings

CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Amicus Therapeutics, Inc. stock logo
FOLD
Amicus Therapeutics
3.00
Buy$20.0088.50% Upside
Insmed Incorporated stock logo
INSM
Insmed
3.00
Buy$44.6483.54% Upside
Prestige Consumer Healthcare Inc. stock logo
PBH
Prestige Consumer Healthcare
2.50
Moderate Buy$110.0057.89% Upside
Pacira BioSciences, Inc. stock logo
PCRX
Pacira BioSciences
3.00
Buy$49.5088.57% Upside
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
2.12
Hold$39.28194.66% Upside

Current Analyst Ratings

Latest INSM, SAGE, PCRX, FOLD, and PBH Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
4/18/2024
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
Scotiabank
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetSector Outperform ➝ Sector Outperform$34.00 ➝ $19.00
4/18/2024
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
Oppenheimer
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetMarket Perform ➝ Market Perform$25.00 ➝ $17.00
4/18/2024
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
Needham & Company LLC
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingHold
4/18/2024
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
TD Cowen
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetBuy ➝ Buy$30.00 ➝ $16.00
4/17/2024
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
Wedbush
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingNeutral ➝ Neutral$24.00
4/17/2024
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingNeutral ➝ Neutral$28.00
4/17/2024
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
Bank of America
Subscribe to MarketBeat All Access for the recommendation accuracy rating
DowngradeNeutral ➝ Underperform$24.00 ➝ $14.00
4/11/2024
Insmed Incorporated stock logo
INSM
Insmed
Barclays
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetOverweight ➝ Overweight$37.00 ➝ $40.00
4/9/2024
Pacira BioSciences, Inc. stock logo
PCRX
Pacira BioSciences
Needham & Company LLC
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingBuy ➝ Buy$45.00
4/1/2024
Insmed Incorporated stock logo
INSM
Insmed
Wells Fargo & Company
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOverweight ➝ Overweight$55.00
3/26/2024
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
JPMorgan Chase & Co.
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetOverweight ➝ Overweight$24.00 ➝ $29.00
(Data available from 4/20/2021 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Sales & Book Value

CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Amicus Therapeutics, Inc. stock logo
FOLD
Amicus Therapeutics
$399.36M7.85N/AN/A$0.55 per share19.29
Insmed Incorporated stock logo
INSM
Insmed
$305.21M11.84N/AN/A($2.32) per share-10.48
Prestige Consumer Healthcare Inc. stock logo
PBH
Prestige Consumer Healthcare
$1.13B3.05$5.13 per share13.58$29.12 per share2.39
Pacira BioSciences, Inc. stock logo
PCRX
Pacira BioSciences
$674.98M1.81$3.88 per share6.76$18.74 per share1.40
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
$86.46M9.27N/AN/A$13.32 per share1.00

Profitability & Earnings

CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Amicus Therapeutics, Inc. stock logo
FOLD
Amicus Therapeutics
-$151.58M-$0.51N/A31.21N/A-37.96%-119.46%-20.40%5/8/2024 (Estimated)
Insmed Incorporated stock logo
INSM
Insmed
-$749.57M-$5.34N/AN/AN/A-245.59%N/A-53.34%5/2/2024 (Estimated)
Prestige Consumer Healthcare Inc. stock logo
PBH
Prestige Consumer Healthcare
-$82.31M-$1.64N/A15.111.84-7.11%14.09%6.39%5/2/2024 (Estimated)
Pacira BioSciences, Inc. stock logo
PCRX
Pacira BioSciences
$41.96M$0.8132.419.28N/A6.22%12.81%6.80%5/1/2024 (Estimated)
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
-$541.49M-$9.06N/AN/AN/A-626.32%-54.41%-49.13%4/25/2024 (Confirmed)

Latest INSM, SAGE, PCRX, FOLD, and PBH Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
4/25/2024N/A
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
-$1.58N/A+$1.58N/AN/AN/A  
2/29/2024Q4 2023
Pacira BioSciences, Inc. stock logo
PCRX
Pacira BioSciences
$0.71$0.71N/A$0.92$180.60 million$181.24 million
2/28/2024Q4 2023
Amicus Therapeutics, Inc. stock logo
FOLD
Amicus Therapeutics
-$0.06-$0.11-$0.05-$0.11$115.11 million$115.08 million
2/22/202412/31/2023
Insmed Incorporated stock logo
INSM
Insmed
-$1.13-$1.28-$0.15-$1.28$82.15 million$83.70 million      
2/14/202412/31/2023
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
-$1.28-$0.55+$0.73-$0.55$60.15 million$77.97 million    
2/8/202412/31/2023
Prestige Consumer Healthcare Inc. stock logo
PBH
Prestige Consumer Healthcare
$1.04$1.06+$0.02$1.06$280.25 million$282.74 million      

Dividends

CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Amicus Therapeutics, Inc. stock logo
FOLD
Amicus Therapeutics
N/AN/AN/AN/AN/A
Insmed Incorporated stock logo
INSM
Insmed
N/AN/AN/AN/AN/A
Prestige Consumer Healthcare Inc. stock logo
PBH
Prestige Consumer Healthcare
$1.902.73%N/AN/A N/A
Pacira BioSciences, Inc. stock logo
PCRX
Pacira BioSciences
N/AN/AN/AN/AN/A
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
N/AN/AN/AN/AN/A

Debt

CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Amicus Therapeutics, Inc. stock logo
FOLD
Amicus Therapeutics
2.42
2.88
2.52
Insmed Incorporated stock logo
INSM
Insmed
N/A
4.12
3.75
Prestige Consumer Healthcare Inc. stock logo
PBH
Prestige Consumer Healthcare
0.75
3.09
1.92
Pacira BioSciences, Inc. stock logo
PCRX
Pacira BioSciences
0.59
5.24
4.17
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
N/A
10.51
10.51

Ownership

Institutional Ownership

CompanyInstitutional Ownership
Amicus Therapeutics, Inc. stock logo
FOLD
Amicus Therapeutics
N/A
Insmed Incorporated stock logo
INSM
Insmed
N/A
Prestige Consumer Healthcare Inc. stock logo
PBH
Prestige Consumer Healthcare
99.95%
Pacira BioSciences, Inc. stock logo
PCRX
Pacira BioSciences
99.73%
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
99.22%

Miscellaneous

CompanyEmployeesShares OutstandingFree FloatOptionable
Amicus Therapeutics, Inc. stock logo
FOLD
Amicus Therapeutics
517295.38 million289.18 millionOptionable
Insmed Incorporated stock logo
INSM
Insmed
373148.55 million141.72 millionOptionable
Prestige Consumer Healthcare Inc. stock logo
PBH
Prestige Consumer Healthcare
56049.65 million48.86 millionOptionable
Pacira BioSciences, Inc. stock logo
PCRX
Pacira BioSciences
71246.50 million43.43 millionOptionable
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
48760.11 million56.80 millionOptionable

INSM, SAGE, PCRX, FOLD, and PBH Headlines

SourceHeadline
Wedbush Weighs in on Sage Therapeutics, Inc.s Q1 2024 Earnings (NASDAQ:SAGE)Wedbush Weighs in on Sage Therapeutics, Inc.'s Q1 2024 Earnings (NASDAQ:SAGE)
americanbankingnews.com - April 20 at 1:32 AM
Sage Therapeutics (NASDAQ:SAGE) Cut to "Sell" at StockNews.comSage Therapeutics (NASDAQ:SAGE) Cut to "Sell" at StockNews.com
marketbeat.com - April 19 at 11:04 PM
Q1 2024 Earnings Estimate for Sage Therapeutics, Inc. (NASDAQ:SAGE) Issued By WedbushQ1 2024 Earnings Estimate for Sage Therapeutics, Inc. (NASDAQ:SAGE) Issued By Wedbush
marketbeat.com - April 19 at 8:17 AM
Sage Therapeutics (NASDAQ:SAGE) Stock Rating Reaffirmed by HC WainwrightSage Therapeutics (NASDAQ:SAGE) Stock Rating Reaffirmed by HC Wainwright
americanbankingnews.com - April 19 at 2:31 AM
Sage Therapeutics (NASDAQ:SAGE) Rating Reiterated by WedbushSage Therapeutics (NASDAQ:SAGE) Rating Reiterated by Wedbush
americanbankingnews.com - April 19 at 2:31 AM
Sage Therapeutics (NASDAQ:SAGE) Cut to Underperform at Bank of AmericaSage Therapeutics (NASDAQ:SAGE) Cut to Underperform at Bank of America
americanbankingnews.com - April 19 at 1:44 AM
Sage Therapeutics (NASDAQ:SAGE) Trading Up 6.2%Sage Therapeutics (NASDAQ:SAGE) Trading Up 6.2%
marketbeat.com - April 18 at 4:33 PM
Sage (SAGE) Down 20% on Parkinsons Study Missing Primary GoalSage (SAGE) Down 20% on Parkinson's Study Missing Primary Goal
zacks.com - April 18 at 12:41 PM
Sage Therapeutics, Inc. (SAGE) May Report Negative Earnings: Know the Trend Ahead of Next Weeks ReleaseSage Therapeutics, Inc. (SAGE) May Report Negative Earnings: Know the Trend Ahead of Next Week's Release
zacks.com - April 18 at 11:07 AM
Scotiabank Lowers Sage Therapeutics (NASDAQ:SAGE) Price Target to $19.00Scotiabank Lowers Sage Therapeutics (NASDAQ:SAGE) Price Target to $19.00
marketbeat.com - April 18 at 10:28 AM
B of A Securities Downgrades Sage Therapeutics (SAGE)B of A Securities Downgrades Sage Therapeutics (SAGE)
msn.com - April 18 at 10:27 AM
In-Depth Examination Of 9 Analyst Recommendations For Sage TherapeuticsIn-Depth Examination Of 9 Analyst Recommendations For Sage Therapeutics
markets.businessinsider.com - April 18 at 10:27 AM
Sage Therapeutics (NASDAQ:SAGE) Given Hold Rating at Needham & Company LLCSage Therapeutics (NASDAQ:SAGE) Given Hold Rating at Needham & Company LLC
marketbeat.com - April 18 at 8:23 AM
Sage Therapeutics (SAGE) Scheduled to Post Earnings on ThursdaySage Therapeutics (SAGE) Scheduled to Post Earnings on Thursday
americanbankingnews.com - April 18 at 2:48 AM
Sage drops dalzanemdor for Parkinson’s after trial flopSage drops dalzanemdor for Parkinson’s after trial flop
pharmaphorum.com - April 17 at 6:40 PM
Phase II PD data from Sage: Precedent set for dalzanemdor?Phase II PD data from Sage: Precedent set for dalzanemdor?
bioworld.com - April 17 at 6:40 PM
Sage Therapeutics stock plunges 20 percent after Parkinson’s drug fails studySage Therapeutics stock plunges 20 percent after Parkinson’s drug fails study
msn.com - April 17 at 6:40 PM
Wedbush Reiterates Neutral Rating for Sage Therapeutics (NASDAQ:SAGE)Wedbush Reiterates Neutral Rating for Sage Therapeutics (NASDAQ:SAGE)
marketbeat.com - April 17 at 3:51 PM
2 Well-Priced Stocks Staging Big Swings Today2 Well-Priced Stocks Staging Big Swings Today
schaeffersresearch.com - April 17 at 3:11 PM
Sage’s dalzanemdor latest victim of Parkinson’sSage’s dalzanemdor latest victim of Parkinson’s
thepharmaletter.com - April 17 at 1:38 PM
Neurodegenerative Disorder-Focused Sage Therapeutics Stock Falls On Disappointing Parkinsons DataNeurodegenerative Disorder-Focused Sage Therapeutics Stock Falls On Disappointing Parkinson's Data
benzinga.com - April 17 at 1:38 PM
Sage Axes Parkinson’s Program for Dalzanemdor After Phase II FlopSage Axes Parkinson’s Program for Dalzanemdor After Phase II Flop
biospace.com - April 17 at 1:38 PM
Sage burns Parkinsons bridge, flunking first of 4 midphase tests for key prospectSage burns Parkinson's bridge, flunking first of 4 midphase tests for key prospect
fiercebiotech.com - April 17 at 1:38 PM
BofA downgrades Sage to underperform, cites failed Parkinsons studyBofA downgrades Sage to underperform, cites failed Parkinson's study
msn.com - April 17 at 1:38 PM

New MarketBeat Followers Over Time

Media Sentiment Over Time

Company Descriptions

Amicus Therapeutics logo

Amicus Therapeutics

NASDAQ:FOLD
Amicus Therapeutics, Inc., a biotechnology company, focuses on discovering, developing, and delivering medicines for rare diseases. Its commercial product and product candidates include Galafold, an oral precision medicine for the treatment of adults with a confirmed diagnosis of Fabry disease and an amenable galactosidase alpha gene variant; and Pombiliti + Opfolda, for the treatment of late onset. It has collaboration and license agreements with the University of Pennsylvania to research and develop parvovirus gene therapy products; and GlaxoSmithKline. Amicus Therapeutics, Inc. was incorporated in 2002 and is headquartered in Princeton, New Jersey.
Insmed logo

Insmed

NASDAQ:INSM
Insmed Incorporated is a global biopharmaceutical company on a mission to transform the lives of patients with serious and rare diseases. Insmed's first commercial product is ARIKAYCE® (amikacin liposome inhalation suspension), which is approved in the United States for the treatment of Mycobacterium avium complex (MAC) lung disease as part of a combination antibacterial drug regimen for adult patients with limited or no alternative treatment options. MAC lung disease is a rare and often chronic infection that can cause irreversible lung damage and can be fatal. Insmed's earlier-stage clinical pipeline includes INS1007, a novel oral reversible inhibitor of dipeptidyl peptidase 1 with therapeutic potential in non-cystic fibrosis bronchiectasis and other inflammatory diseases, and INS1009, an inhaled formulation of a treprostinil prodrug that may offer a differentiated product profile for rare pulmonary disorders, including pulmonary arterial hypertension.
Prestige Consumer Healthcare logo

Prestige Consumer Healthcare

NYSE:PBH
Prestige Consumer Healthcare Inc., together with its subsidiaries, develops, manufactures, markets, distributes, and sells over-the-counter (OTC) health and personal care products in the United States and internationally. The company operates in two segments, North American OTC Healthcare and International OTC Healthcare. It offers BC/Goody's analgesic powders, Boudreaux's Butt Paste baby ointments, Chloraseptic sore throat liquids and lozenges, Clear Eyes for eye redness relief, Compound W wart removals, DenTek for PEG oral care, Debrox ear wax removals, and Dramamine for motion sickness relief. The company also provides Fleet adult enemas/suppositories, Gaviscon upset stomach remedies, Luden's cough drops, Monistat vaginal anti-fungal, Nix lice/parasite treatments, Summer's Eve feminine hygiene, TheraTears dry eye relief, Fess nasal saline spray and washes, and Hydralyte for oral rehydration products. It sells its products through mass merchandisers; and drug, food, dollar, convenience, and club stores, as well as e-commerce channels. The company was formerly known as Prestige Brands Holdings, Inc. and changed its name to Prestige Consumer Healthcare Inc. in August 2018. Prestige Consumer Healthcare Inc. was founded in 1996 and is headquartered in Tarrytown, New York.
Pacira BioSciences logo

Pacira BioSciences

NASDAQ:PCRX
Pacira BioSciences, Inc. engages in the development, manufacture, marketing, distribution, and sale of non-opioid pain management and regenerative health solutions to healthcare practitioners in the United States. The company offers EXPAREL, a bupivacaine liposome injectable suspension; ZILRETTA, a triamcinolone acetonide extended-release injectable suspension; and iovera system, a non-opioid handheld cryoanalgesia device used to produce controlled doses of cold temperature to targeted nerves. It has a development and commercialization, and supply agreement with Aratana Therapeutics, Inc. for NOCITA, a bupivacaine liposome injectable suspension product. The company was formerly known as Pacira Pharmaceuticals, Inc. and changed its name to Pacira BioSciences, Inc. in April 2019. Pacira BioSciences, Inc. was incorporated in 2006 and is headquartered in Tampa, Florida.
Sage Therapeutics logo

Sage Therapeutics

NASDAQ:SAGE
Sage Therapeutics, Inc., a biopharmaceutical company, develops and commercializes brain health medicines. Its product candidates include ZULRESSO, a CIV injection for the treatment of postpartum depression (PPD) in adults; and ZURZUVAE, a neuroactive steroid, a positive allosteric modulator of GABAA receptors, targeting both synaptic and extrasynaptic GABAA receptors, for the treatment of postpartum depression. Its product pipeline also comprises SAGE-324, a compound that is in Phase II clinical trial to treat essential tremors, as well as has completed Phase I clinical trial for epilepsy and Parkinson's diseases; and SAGE-718, an oxysterol-based positive allosteric modulator of the NMDA receptor, which is in Phase II clinical trial for the treatment of depression, Huntington's disease, Parkinson's diseases, Alzheimer's disease, attention deficit hyperactivity disorder, schizophrenia, and neuropathic pain. The company has a strategic collaboration with Shionogi & Co., Ltd. for the development and commercialization of zuranolone in Japan, Taiwan, and South Korea; and a collaboration and license agreement with Biogen MA Inc. to jointly develop and commercialize SAGE-217 and SAGE-324 products. The company was formerly known as Sterogen Biopharma, Inc. and changed its name to Sage Therapeutics, Inc. in September 2011. Sage Therapeutics, Inc. was incorporated in 2010 and is headquartered in Cambridge, Massachusetts.