S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold
S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold
S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold
S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold

Compare Stocks

Comparative Price Performance Over Time

Compare Stocks - Price & Volume

CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Bausch Health Companies Inc. stock logo
BHC
Bausch Health Companies
$8.69
+1.0%
$9.29
$5.57
$11.46
$3.18B0.852.79 million shs2.90 million shs
Catalent, Inc. stock logo
CTLT
Catalent
$55.48
-0.6%
$56.81
$31.45
$60.20
$10.04B1.22.58 million shs1.59 million shs
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
$40.68
-0.3%
$43.86
$34.32
$54.44
$5.93B0.391.15 million shs845,983 shs
Perrigo Company plc stock logo
PRGO
Perrigo
$30.80
+2.9%
$30.62
$25.77
$40.28
$4.17B0.641.86 million shs1.17 million shs
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
$13.33
+2.2%
$19.85
$10.92
$59.99
$801.27M0.861.01 million shs1.26 million shs
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Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Bausch Health Companies Inc. stock logo
BHC
Bausch Health Companies
+0.93%-0.74%-9.38%+6.63%+15.41%
Catalent, Inc. stock logo
CTLT
Catalent
-0.52%-1.46%-0.72%+12.74%+28.81%
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
-0.32%-2.54%-4.91%-20.20%+10.75%
Perrigo Company plc stock logo
PRGO
Perrigo
+2.87%+1.57%-1.61%-6.92%-14.96%
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
+2.26%-13.67%-32.27%-48.75%-71.90%

MarketRank™

CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Bausch Health Companies Inc. stock logo
BHC
Bausch Health Companies
3.9487 of 5 stars
3.23.00.04.03.11.70.6
Catalent, Inc. stock logo
CTLT
Catalent
3.2604 of 5 stars
1.14.00.04.62.80.81.9
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
4.1642 of 5 stars
4.32.00.03.02.02.50.6
Perrigo Company plc stock logo
PRGO
Perrigo
4.9295 of 5 stars
3.53.04.23.51.43.32.5
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
3.9518 of 5 stars
4.11.00.04.32.11.70.6

Analyst Ratings

CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Bausch Health Companies Inc. stock logo
BHC
Bausch Health Companies
2.33
Hold$13.0049.60% Upside
Catalent, Inc. stock logo
CTLT
Catalent
2.15
Hold$52.46-5.45% Downside
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
2.69
Moderate Buy$56.0837.85% Upside
Perrigo Company plc stock logo
PRGO
Perrigo
3.00
Buy$40.6732.03% Upside
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
2.12
Hold$39.28194.66% Upside

Current Analyst Ratings

Latest IONS, BHC, PRGO, SAGE, and CTLT Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
4/18/2024
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
Scotiabank
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetSector Outperform ➝ Sector Outperform$34.00 ➝ $19.00
4/18/2024
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
Oppenheimer
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetMarket Perform ➝ Market Perform$25.00 ➝ $17.00
4/18/2024
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
Needham & Company LLC
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingHold
4/18/2024
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
TD Cowen
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetBuy ➝ Buy$30.00 ➝ $16.00
4/17/2024
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
Wedbush
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingNeutral ➝ Neutral$24.00
4/17/2024
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingNeutral ➝ Neutral$28.00
4/17/2024
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
Bank of America
Subscribe to MarketBeat All Access for the recommendation accuracy rating
DowngradeNeutral ➝ Underperform$24.00 ➝ $14.00
4/12/2024
Bausch Health Companies Inc. stock logo
BHC
Bausch Health Companies
Royal Bank of Canada
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingSector Perform ➝ Sector Perform$12.00
4/12/2024
Perrigo Company plc stock logo
PRGO
Perrigo
Canaccord Genuity Group
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingBuy ➝ Buy$42.00
4/10/2024
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
Wolfe Research
Subscribe to MarketBeat All Access for the recommendation accuracy rating
UpgradePeer Perform ➝ Outperform$58.00
4/9/2024
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
William Blair
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOutperform
(Data available from 4/20/2021 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Sales & Book Value

CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Bausch Health Companies Inc. stock logo
BHC
Bausch Health Companies
$8.76B0.36$7.24 per share1.20($0.23) per share-37.78
Catalent, Inc. stock logo
CTLT
Catalent
$4.28B2.35$3.22 per share17.25$25.58 per share2.17
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
$787.65M7.53N/AN/A$2.70 per share15.07
Perrigo Company plc stock logo
PRGO
Perrigo
$4.66B0.90$5.40 per share5.70$35.19 per share0.88
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
$86.46M9.27N/AN/A$13.32 per share1.00

Profitability & Earnings

CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Bausch Health Companies Inc. stock logo
BHC
Bausch Health Companies
-$592M-$1.62N/A2.14N/A-6.76%5,147.48%4.84%5/2/2024 (Estimated)
Catalent, Inc. stock logo
CTLT
Catalent
-$256M-$6.80N/A46.626.04-29.91%-2.43%-0.98%6/10/2024 (Estimated)
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
-$366.29M-$2.56N/AN/AN/A-46.32%-90.29%-12.39%5/1/2024 (Estimated)
Perrigo Company plc stock logo
PRGO
Perrigo
-$12.70M-$0.10N/A9.57N/A-0.27%7.34%3.24%5/14/2024 (Estimated)
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
-$541.49M-$9.06N/AN/AN/A-626.32%-54.41%-49.13%4/25/2024 (Confirmed)

Latest IONS, BHC, PRGO, SAGE, and CTLT Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
4/25/2024N/A
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
-$1.58N/A+$1.58N/AN/AN/A  
2/27/202412/31/2023
Perrigo Company plc stock logo
PRGO
Perrigo
$0.83$0.86+$0.03$1.96$1.17 billion$1.16 billion      
2/22/2024Q4 2023
Bausch Health Companies Inc. stock logo
BHC
Bausch Health Companies
$1.01$1.15+$0.14$2.41$2.29 billion$2.41 billion    
2/21/202412/31/2023
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
-$0.78-$0.06+$0.72-$0.06$176.01 million$325.00 million      
2/14/202412/31/2023
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
-$1.28-$0.55+$0.73-$0.55$60.15 million$77.97 million    
2/9/202412/31/2023
Catalent, Inc. stock logo
CTLT
Catalent
-$0.02-$0.24-$0.22$0.46$1.01 billion$1.03 billion    

Dividends

CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Bausch Health Companies Inc. stock logo
BHC
Bausch Health Companies
N/AN/AN/AN/AN/A
Catalent, Inc. stock logo
CTLT
Catalent
N/AN/AN/AN/AN/A
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
N/AN/AN/AN/AN/A
Perrigo Company plc stock logo
PRGO
Perrigo
$1.103.57%+6.66%N/A 22 Years
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
N/AN/AN/AN/AN/A

Latest IONS, BHC, PRGO, SAGE, and CTLT Dividends

AnnouncementCompanyPeriodAmountYieldEx-Dividend DateRecord DatePayable Date
2/26/2024
Perrigo Company plc stock logo
PRGO
Perrigo
quarterly$0.27603.43%3/7/20243/8/20243/26/2024
(Data available from 1/1/2013 forward)

Debt

CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Bausch Health Companies Inc. stock logo
BHC
Bausch Health Companies
N/A
1.30
0.94
Catalent, Inc. stock logo
CTLT
Catalent
1.34
2.48
1.73
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
3.18
5.90
5.83
Perrigo Company plc stock logo
PRGO
Perrigo
0.76
1.79
1.07
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
N/A
10.51
10.51

Ownership

Institutional Ownership

CompanyInstitutional Ownership
Bausch Health Companies Inc. stock logo
BHC
Bausch Health Companies
78.65%
Catalent, Inc. stock logo
CTLT
Catalent
N/A
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
93.86%
Perrigo Company plc stock logo
PRGO
Perrigo
95.91%
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
99.22%

Insider Ownership

CompanyInsider Ownership
Bausch Health Companies Inc. stock logo
BHC
Bausch Health Companies
8.12%
Catalent, Inc. stock logo
CTLT
Catalent
0.31%
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
2.65%
Perrigo Company plc stock logo
PRGO
Perrigo
0.70%
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
5.50%

Miscellaneous

CompanyEmployeesShares OutstandingFree FloatOptionable
Bausch Health Companies Inc. stock logo
BHC
Bausch Health Companies
20,270365.41 million335.74 millionOptionable
Catalent, Inc. stock logo
CTLT
Catalent
17,800180.97 million180.41 millionOptionable
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
927145.75 million141.89 millionOptionable
Perrigo Company plc stock logo
PRGO
Perrigo
9,140135.52 million134.57 millionOptionable
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
48760.11 million56.80 millionOptionable

IONS, BHC, PRGO, SAGE, and CTLT Headlines

SourceHeadline
Wedbush Weighs in on Sage Therapeutics, Inc.s Q1 2024 Earnings (NASDAQ:SAGE)Wedbush Weighs in on Sage Therapeutics, Inc.'s Q1 2024 Earnings (NASDAQ:SAGE)
americanbankingnews.com - April 20 at 1:32 AM
Sage Therapeutics (NASDAQ:SAGE) Cut to "Sell" at StockNews.comSage Therapeutics (NASDAQ:SAGE) Cut to "Sell" at StockNews.com
marketbeat.com - April 19 at 11:04 PM
Q1 2024 Earnings Estimate for Sage Therapeutics, Inc. (NASDAQ:SAGE) Issued By WedbushQ1 2024 Earnings Estimate for Sage Therapeutics, Inc. (NASDAQ:SAGE) Issued By Wedbush
marketbeat.com - April 19 at 8:17 AM
Sage Therapeutics (NASDAQ:SAGE) Stock Rating Reaffirmed by HC WainwrightSage Therapeutics (NASDAQ:SAGE) Stock Rating Reaffirmed by HC Wainwright
americanbankingnews.com - April 19 at 2:31 AM
Sage Therapeutics (NASDAQ:SAGE) Rating Reiterated by WedbushSage Therapeutics (NASDAQ:SAGE) Rating Reiterated by Wedbush
americanbankingnews.com - April 19 at 2:31 AM
Sage Therapeutics (NASDAQ:SAGE) Cut to Underperform at Bank of AmericaSage Therapeutics (NASDAQ:SAGE) Cut to Underperform at Bank of America
americanbankingnews.com - April 19 at 1:44 AM
Sage Therapeutics (NASDAQ:SAGE) Trading Up 6.2%Sage Therapeutics (NASDAQ:SAGE) Trading Up 6.2%
marketbeat.com - April 18 at 4:33 PM
Sage (SAGE) Down 20% on Parkinsons Study Missing Primary GoalSage (SAGE) Down 20% on Parkinson's Study Missing Primary Goal
zacks.com - April 18 at 12:41 PM
Sage Therapeutics, Inc. (SAGE) May Report Negative Earnings: Know the Trend Ahead of Next Weeks ReleaseSage Therapeutics, Inc. (SAGE) May Report Negative Earnings: Know the Trend Ahead of Next Week's Release
zacks.com - April 18 at 11:07 AM
Scotiabank Lowers Sage Therapeutics (NASDAQ:SAGE) Price Target to $19.00Scotiabank Lowers Sage Therapeutics (NASDAQ:SAGE) Price Target to $19.00
marketbeat.com - April 18 at 10:28 AM
B of A Securities Downgrades Sage Therapeutics (SAGE)B of A Securities Downgrades Sage Therapeutics (SAGE)
msn.com - April 18 at 10:27 AM
In-Depth Examination Of 9 Analyst Recommendations For Sage TherapeuticsIn-Depth Examination Of 9 Analyst Recommendations For Sage Therapeutics
markets.businessinsider.com - April 18 at 10:27 AM
Sage Therapeutics (NASDAQ:SAGE) Given Hold Rating at Needham & Company LLCSage Therapeutics (NASDAQ:SAGE) Given Hold Rating at Needham & Company LLC
marketbeat.com - April 18 at 8:23 AM
Sage Therapeutics (SAGE) Scheduled to Post Earnings on ThursdaySage Therapeutics (SAGE) Scheduled to Post Earnings on Thursday
americanbankingnews.com - April 18 at 2:48 AM
Sage drops dalzanemdor for Parkinson’s after trial flopSage drops dalzanemdor for Parkinson’s after trial flop
pharmaphorum.com - April 17 at 6:40 PM
Phase II PD data from Sage: Precedent set for dalzanemdor?Phase II PD data from Sage: Precedent set for dalzanemdor?
bioworld.com - April 17 at 6:40 PM
Sage Therapeutics stock plunges 20 percent after Parkinson’s drug fails studySage Therapeutics stock plunges 20 percent after Parkinson’s drug fails study
msn.com - April 17 at 6:40 PM
Wedbush Reiterates Neutral Rating for Sage Therapeutics (NASDAQ:SAGE)Wedbush Reiterates Neutral Rating for Sage Therapeutics (NASDAQ:SAGE)
marketbeat.com - April 17 at 3:51 PM
2 Well-Priced Stocks Staging Big Swings Today2 Well-Priced Stocks Staging Big Swings Today
schaeffersresearch.com - April 17 at 3:11 PM
Sage’s dalzanemdor latest victim of Parkinson’sSage’s dalzanemdor latest victim of Parkinson’s
thepharmaletter.com - April 17 at 1:38 PM
Neurodegenerative Disorder-Focused Sage Therapeutics Stock Falls On Disappointing Parkinsons DataNeurodegenerative Disorder-Focused Sage Therapeutics Stock Falls On Disappointing Parkinson's Data
benzinga.com - April 17 at 1:38 PM
Sage Axes Parkinson’s Program for Dalzanemdor After Phase II FlopSage Axes Parkinson’s Program for Dalzanemdor After Phase II Flop
biospace.com - April 17 at 1:38 PM
Sage burns Parkinsons bridge, flunking first of 4 midphase tests for key prospectSage burns Parkinson's bridge, flunking first of 4 midphase tests for key prospect
fiercebiotech.com - April 17 at 1:38 PM
BofA downgrades Sage to underperform, cites failed Parkinsons studyBofA downgrades Sage to underperform, cites failed Parkinson's study
msn.com - April 17 at 1:38 PM

New MarketBeat Followers Over Time

Media Sentiment Over Time

Top Headlines

All Headlines

Company Descriptions

Bausch Health Companies logo

Bausch Health Companies

NYSE:BHC
Bausch Health Companies Inc. operates as a diversified specialty pharmaceutical and medical device company in the United States and internationally. It develops, manufactures, and markets a range of products primarily in gastroenterology, hepatology, neurology, dermatology, international pharmaceuticals, over-the-counter (OTC) products, aesthetic medical devices, and eye health. The company operates through five segments: Salix, International, Solta Medical, Diversified, and Bausch + Lomb. The Salix segment provides gastroenterology products in the United States. The International segment sells aesthetic medical devices, branded pharmaceuticals, generic pharmaceuticals, and OTC products internationally. The Solta Medical segment engages in the sale of aesthetic medical devices. The Diversified segment offers pharmaceutical products in the areas of neurology and certain other therapeutic classes; generic products; ortho dermatologic; and dentistry products in the United States. The Bausch + Lomb segment offers products in the areas of vision care, surgical, and ophthalmic pharmaceuticals products. The company was formerly known as Valeant Pharmaceuticals International, Inc. and changed its name to Bausch Health Companies Inc. in July 2018. Bausch Health Companies Inc. is headquartered in Laval, Canada.
Catalent logo

Catalent

NYSE:CTLT
Catalent, Inc., together with its subsidiaries, develops and manufactures solutions for drugs, protein-based biologics, cell and gene therapies, and consumer health products worldwide. It operates in two segments, Biologics, and Pharma and Consumer Health. The Biologics segment provides formulation, development, and manufacturing for biologic proteins, cell gene, and other nucleic acid therapies; pDNA, iPSCs, oncolytic viruses, and vaccines; formulation, development, and manufacturing for parenteral dose forms, including vials, prefilled syringes, and cartridges; and analytical development and testing services for large molecules. The Pharma and Consumer Health segment offers formulation, development, and manufacturing services for soft capsules for use in a range of customer products, such as prescription drugs, over-the-counter medications, dietary supplements, unit-dose cosmetics, and animal health medicinal preparations; and oral, nasal, inhaled, and topical dose forms. This segment also provides clinical supply services through manufacturing, packaging, storage, distribution, and inventory management for small-molecule drugs, protein-based biologics, and cell and gene therapies in clinical trials; and pre-clinical screening, formulation, analytical development, and current good manufacturing practices manufacturing at clinical and commercial scale for softgel capsule, Zydis fast-dissolve tablets, oral solid-dose formats, dry powder inhalers, and nasal delivery devices. The company also offers FlexDirect direct-to-patient and FastChain demand-led clinical supply solutions; fill and finish operations for injectable products; and integrated development and product supply chain solutions. It serves pharmaceutical, biotechnology, and consumer health companies; and companies in other healthcare market segments, such as animal health and medical devices, as well as in cosmetics industries. The company was founded in 1933 and is headquartered in Somerset, New Jersey.
Ionis Pharmaceuticals logo

Ionis Pharmaceuticals

NASDAQ:IONS
Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen as a monthly self-administered subcutaneous injection to treat all types of ATTR; Olezarsen for patients with FCS and severe hypertriglyceridemia (SHTG); Donidalorsen for patients with hereditary angioedema; ION363 for patients with amyotrophic lateral sclerosis; Tofersen to inhibit the production of superoxide dismutase 1; Pelacarsen for patients with established cardiovascular disease and elevated lipoprotein(a); and Bepirovirsen to inhibit the production of viral proteins associated with hepatitis B virus. In addition, the company develops IONIS-FB-LRx to inhibit the production of complement factor B and the alternative complement pathway; and ION224 to reduce the production of diacylglycerol acyltransferase 2. It has a strategic collaboration with Biogen for the treatment of neurological disorders; and collaboration and license agreement with Metagenomi, Inc, AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis, Roche, Swedish Orphan Biovitrum AB, and PTC Therapeutics. The company was incorporated in 1989 and is based in Carlsbad, California.
Perrigo logo

Perrigo

NYSE:PRGO
Perrigo Company plc provides over-the-counter health and wellness solutions to enhance individual well-being in the United States, Europe, and internationally. It operates through Consumer Self-Care Americas and Consumer Self-Care International segments. The company develops, manufactures, markets, and distributes self-care consumer products, such as upper respiratory products, including cough suppressants, expectorants, and sinus and allergy relief; nutrition products consisting of infant formulas and nutritional beverages; digestive health products, including antacids, anti-diarrheal, and anti-heartburn; pain and sleep-aids products comprising pain relievers and fever reducers; and oral care products, which include toothbrushes, toothbrush replacement heads, floss, flossers, whitening products, and toothbrush covers. It also offers healthy lifestyle products, such as smoking cessation, well-being, and weight management products; skin care products consisting of dermatological care, scar management, lice treatment, and other products for various skin conditions; women's health products comprising feminine hygiene and contraceptives; vitamins, minerals, and supplements; rare diseases business; and other miscellaneous self-care products. The company sells its products under the Compeed, Dr. Fresh, Firefly, Good Sense, Good Start, Mederma, Nasonex, Plackers, Prevacid24HR, REACH, Rembrandt, Steripod, Opill, Solpadeine, Coldrex, Physiomer, NiQuitin, ACO, ellaOne, Compeed Stops, XLS, Arterin, Davitamon, Apiserum, Abtei, and Nicorette brands. It also offers contract manufacturing services. The company sells its products through retail drug, supermarket, and mass merchandise chains; e-commerce stores; wholesalers; pharmacies; drug and grocery retailers; and para-pharmacies. The company was formerly known as Perrigo Company and changed its name to Perrigo Company plc in December 2013. Perrigo Company plc was founded in 1887 and is headquartered in Dublin, Ireland.
Sage Therapeutics logo

Sage Therapeutics

NASDAQ:SAGE
Sage Therapeutics, Inc., a biopharmaceutical company, develops and commercializes brain health medicines. Its product candidates include ZULRESSO, a CIV injection for the treatment of postpartum depression (PPD) in adults; and ZURZUVAE, a neuroactive steroid, a positive allosteric modulator of GABAA receptors, targeting both synaptic and extrasynaptic GABAA receptors, for the treatment of postpartum depression. Its product pipeline also comprises SAGE-324, a compound that is in Phase II clinical trial to treat essential tremors, as well as has completed Phase I clinical trial for epilepsy and Parkinson's diseases; and SAGE-718, an oxysterol-based positive allosteric modulator of the NMDA receptor, which is in Phase II clinical trial for the treatment of depression, Huntington's disease, Parkinson's diseases, Alzheimer's disease, attention deficit hyperactivity disorder, schizophrenia, and neuropathic pain. The company has a strategic collaboration with Shionogi & Co., Ltd. for the development and commercialization of zuranolone in Japan, Taiwan, and South Korea; and a collaboration and license agreement with Biogen MA Inc. to jointly develop and commercialize SAGE-217 and SAGE-324 products. The company was formerly known as Sterogen Biopharma, Inc. and changed its name to Sage Therapeutics, Inc. in September 2011. Sage Therapeutics, Inc. was incorporated in 2010 and is headquartered in Cambridge, Massachusetts.