S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold
S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold
S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold
S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold

Compare Stocks

Comparative Price Performance Over Time

Compare Stocks - Price & Volume

CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
$293.61
-1.3%
$300.87
$175.37
$329.87
$22.16B0.93470,207 shs551,377 shs
Atreca, Inc. stock logo
BCEL
Atreca
$0.08
$0.17
$0.05
$1.26
$3.05M1.096.91 million shs14,041 shs
Clovis Oncology stock logo
CLVS
Clovis Oncology
$0.43
$0.08
$3.32
$11.60M0.248.88 million shs1.16 million shs
Ovid Therapeutics Inc. stock logo
OVID
Ovid Therapeutics
$3.23
+0.6%
$3.25
$2.57
$4.14
$228.39M0.71197,243 shs176,627 shs
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
$39.88
-1.1%
$44.80
$27.99
$50.99
$3.01B1.15402,992 shs362,875 shs
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Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
-1.34%-5.54%-6.58%+14.34%+29.72%
Atreca, Inc. stock logo
BCEL
Atreca
+1.18%-4.94%+24.19%-74.33%-92.22%
Clovis Oncology stock logo
CLVS
Clovis Oncology
0.00%0.00%0.00%0.00%0.00%
Ovid Therapeutics Inc. stock logo
OVID
Ovid Therapeutics
+0.62%+0.94%+15.77%+2.87%+6.95%
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
-1.07%-3.44%-8.93%-8.89%+4.95%

MarketRank™

CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
2.787 of 5 stars
2.54.00.00.02.31.72.5
Atreca, Inc. stock logo
BCEL
Atreca
4.3639 of 5 stars
3.05.00.04.63.00.81.3
Clovis Oncology stock logo
CLVS
Clovis Oncology
N/AN/AN/AN/AN/AN/AN/AN/A
Ovid Therapeutics Inc. stock logo
OVID
Ovid Therapeutics
4.6124 of 5 stars
3.53.00.04.63.44.20.6
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
1.5932 of 5 stars
3.52.00.00.02.02.50.0

Analyst Ratings

CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
2.90
Moderate Buy$312.646.48% Upside
Atreca, Inc. stock logo
BCEL
Atreca
2.00
Hold$4.005,094.81% Upside
Clovis Oncology stock logo
CLVS
Clovis Oncology
N/AN/AN/AN/A
Ovid Therapeutics Inc. stock logo
OVID
Ovid Therapeutics
3.00
Buy$9.00178.64% Upside
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
3.00
Buy$59.4449.06% Upside

Current Analyst Ratings

Latest OVID, XENE, AXON, BCEL, and CLVS Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
4/12/2024
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
Needham & Company LLC
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingBuy ➝ Buy$62.00
4/11/2024
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
JPMorgan Chase & Co.
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetOverweight ➝ Overweight$330.00 ➝ $365.00
4/10/2024
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
Needham & Company LLC
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetBuy ➝ Buy$315.00 ➝ $400.00
4/10/2024
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
Cantor Fitzgerald
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOverweight ➝ Overweight$65.00
4/5/2024
Ovid Therapeutics Inc. stock logo
OVID
Ovid Therapeutics
Wedbush
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOutperform$8.00
3/13/2024
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
Argus
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageBuy$380.00
3/1/2024
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
Royal Bank of Canada
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetOutperform ➝ Outperform$56.00 ➝ $55.00
3/1/2024
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
Wedbush
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetOutperform ➝ Outperform$46.00 ➝ $51.00
3/1/2024
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
Needham & Company LLC
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetBuy ➝ Buy$50.00 ➝ $62.00
2/29/2024
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
Barclays
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetOverweight ➝ Overweight$296.00 ➝ $308.00
2/28/2024
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
Morgan Stanley
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetEqual Weight ➝ Equal Weight$250.00 ➝ $285.00
(Data available from 4/20/2021 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Sales & Book Value

CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
$1.56B14.17$3.04 per share96.48$21.51 per share13.65
Atreca, Inc. stock logo
BCEL
Atreca
N/AN/AN/AN/A$2.01 per shareN/A
Clovis Oncology stock logo
CLVS
Clovis Oncology
$148.76M0.00N/AN/A($2.15) per share0.00
Ovid Therapeutics Inc. stock logo
OVID
Ovid Therapeutics
$390K585.62N/AN/A$1.24 per share2.60
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
$9.43M319.00N/AN/A$14.18 per share2.81

Profitability & Earnings

CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
$174.23M$2.30127.6589.51N/A11.14%14.11%6.61%5/14/2024 (Estimated)
Atreca, Inc. stock logo
BCEL
Atreca
-$97.16M-$2.50N/AN/AN/AN/A-157.90%-71.39%5/8/2024 (Estimated)
Clovis Oncology stock logo
CLVS
Clovis Oncology
-$264.52M-$1.83N/AN/AN/A-189.37%N/A-57.78%N/A
Ovid Therapeutics Inc. stock logo
OVID
Ovid Therapeutics
-$52.34M-$0.75N/AN/AN/A-13,351.53%-49.76%-38.16%5/3/2024 (Estimated)
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
-$182.39M-$2.72N/AN/AN/AN/A-25.18%-23.99%5/14/2024 (Estimated)

Latest OVID, XENE, AXON, BCEL, and CLVS Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
3/8/2024Q4 2023
Ovid Therapeutics Inc. stock logo
OVID
Ovid Therapeutics
-$0.17-$0.22-$0.05-$0.22$0.10 million$0.14 million
2/29/2024Q4 2023
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
-$0.76-$0.64+$0.12-$0.64$2.30 millionN/A    
2/27/2024Q4 2023
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
$0.48$0.77+$0.29$0.79$418.97 million$432.14 million

Dividends

CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
N/AN/AN/AN/AN/A
Atreca, Inc. stock logo
BCEL
Atreca
N/AN/AN/AN/AN/A
Clovis Oncology stock logo
CLVS
Clovis Oncology
N/AN/AN/AN/AN/A
Ovid Therapeutics Inc. stock logo
OVID
Ovid Therapeutics
N/AN/AN/AN/AN/A
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
N/AN/AN/AN/AN/A

Debt

CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
0.42
3.00
2.66
Atreca, Inc. stock logo
BCEL
Atreca
N/A
1.58
1.58
Clovis Oncology stock logo
CLVS
Clovis Oncology
N/A
0.14
0.12
Ovid Therapeutics Inc. stock logo
OVID
Ovid Therapeutics
0.17
9.55
9.55
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
N/A
23.65
23.65

Ownership

Institutional Ownership

CompanyInstitutional Ownership
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
79.08%
Atreca, Inc. stock logo
BCEL
Atreca
37.47%
Clovis Oncology stock logo
CLVS
Clovis Oncology
24.53%
Ovid Therapeutics Inc. stock logo
OVID
Ovid Therapeutics
72.24%
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
95.45%

Insider Ownership

CompanyInsider Ownership
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
6.10%
Atreca, Inc. stock logo
BCEL
Atreca
11.30%
Clovis Oncology stock logo
CLVS
Clovis Oncology
4.40%
Ovid Therapeutics Inc. stock logo
OVID
Ovid Therapeutics
12.60%
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
5.43%

Miscellaneous

CompanyEmployeesShares OutstandingFree FloatOptionable
Axon Enterprise, Inc. stock logo
AXON
Axon Enterprise
4,26075.46 million70.86 millionOptionable
Atreca, Inc. stock logo
BCEL
Atreca
9039.62 million35.15 millionOptionable
Clovis Oncology stock logo
CLVS
Clovis Oncology
N/A144.96 million138.58 millionOptionable
Ovid Therapeutics Inc. stock logo
OVID
Ovid Therapeutics
4070.71 million61.80 millionOptionable
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
25175.43 million71.34 millionOptionable

OVID, XENE, AXON, BCEL, and CLVS Headlines

SourceHeadline
Investors Purchase High Volume of Put Options on Xenon Pharmaceuticals (NASDAQ:XENE)Investors Purchase High Volume of Put Options on Xenon Pharmaceuticals (NASDAQ:XENE)
americanbankingnews.com - April 18 at 3:04 AM
Xenon Pharmaceuticals Showcases XEN1101 at the American Academy of Neurology 2024 Annual MeetingXenon Pharmaceuticals Showcases XEN1101 at the American Academy of Neurology 2024 Annual Meeting
globenewswire.com - April 16 at 8:30 AM
Xenon Pharmaceuticals Inc. (NASDAQ:XENE) Given Consensus Rating of "Buy" by AnalystsXenon Pharmaceuticals Inc. (NASDAQ:XENE) Given Consensus Rating of "Buy" by Analysts
americanbankingnews.com - April 16 at 2:34 AM
Xenon Pharmaceuticals (NASDAQ:XENE) Given "Buy" Rating at Needham & Company LLCXenon Pharmaceuticals (NASDAQ:XENE) Given "Buy" Rating at Needham & Company LLC
americanbankingnews.com - April 14 at 3:36 AM
Needham & Company LLC Reiterates Buy Rating for Xenon Pharmaceuticals (NASDAQ:XENE)Needham & Company LLC Reiterates Buy Rating for Xenon Pharmaceuticals (NASDAQ:XENE)
marketbeat.com - April 12 at 8:14 AM
Cantor Fitzgerald Reaffirms Overweight Rating for Xenon Pharmaceuticals (NASDAQ:XENE)Cantor Fitzgerald Reaffirms Overweight Rating for Xenon Pharmaceuticals (NASDAQ:XENE)
americanbankingnews.com - April 11 at 5:00 AM
Xenon Pharmaceuticals Inc (XENE)Xenon Pharmaceuticals Inc (XENE)
investing.com - April 10 at 12:10 PM
Xenon Pharmaceuticals to Present at the 2024 Bloom Burton & Co. Healthcare Investor ConferenceXenon Pharmaceuticals to Present at the 2024 Bloom Burton & Co. Healthcare Investor Conference
globenewswire.com - April 10 at 8:30 AM
Xenon Pharmaceuticals to Present at the 23rd Annual Needham Virtual Healthcare ConferenceXenon Pharmaceuticals to Present at the 23rd Annual Needham Virtual Healthcare Conference
globenewswire.com - April 4 at 4:01 PM
SG Americas Securities LLC Sells 38,146 Shares of Xenon Pharmaceuticals Inc. (NASDAQ:XENE)SG Americas Securities LLC Sells 38,146 Shares of Xenon Pharmaceuticals Inc. (NASDAQ:XENE)
marketbeat.com - April 2 at 4:18 AM
Assenagon Asset Management S.A. Sells 47,962 Shares of Xenon Pharmaceuticals Inc. (NASDAQ:XENE)Assenagon Asset Management S.A. Sells 47,962 Shares of Xenon Pharmaceuticals Inc. (NASDAQ:XENE)
marketbeat.com - April 1 at 4:43 AM
Xenon Pharmaceuticals IncXenon Pharmaceuticals Inc
money.usnews.com - March 21 at 10:13 AM
Xenon Pharmaceuticals (NASDAQ:XENE) Is In A Good Position To Deliver On Growth PlansXenon Pharmaceuticals (NASDAQ:XENE) Is In A Good Position To Deliver On Growth Plans
finance.yahoo.com - March 19 at 8:26 AM
XENE Apr 2024 47.500 putXENE Apr 2024 47.500 put
finance.yahoo.com - March 16 at 1:48 PM
Xenon Pharmaceuticals to Present at Stifel 2024 Virtual CNS DaysXenon Pharmaceuticals to Present at Stifel 2024 Virtual CNS Days
globenewswire.com - March 12 at 4:01 PM
Insider Selling: Xenon Pharmaceuticals Inc. (NASDAQ:XENE) EVP Sells 7,137 Shares of StockInsider Selling: Xenon Pharmaceuticals Inc. (NASDAQ:XENE) EVP Sells 7,137 Shares of Stock
insidertrades.com - March 11 at 6:41 AM
Insider Sell: EVP, Strategy & Innovation Sherrington Robin Sells 7,137 Shares of Xenon ...Insider Sell: EVP, Strategy & Innovation Sherrington Robin Sells 7,137 Shares of Xenon ...
finance.yahoo.com - March 9 at 12:06 AM
Xenon Pharmaceuticals to Present at Leerink Partners Global Biopharma Conference 2024Xenon Pharmaceuticals to Present at Leerink Partners Global Biopharma Conference 2024
globenewswire.com - March 5 at 4:01 PM
Buy Rating Affirmed for Xenon Pharmaceuticals on Strong Neurological Pipeline ProgressBuy Rating Affirmed for Xenon Pharmaceuticals on Strong Neurological Pipeline Progress
markets.businessinsider.com - March 5 at 10:33 AM
Xenon Pharmaceuticals Inc. (XENE) Q4 2023 Earnings Call TranscriptXenon Pharmaceuticals Inc. (XENE) Q4 2023 Earnings Call Transcript
seekingalpha.com - March 2 at 2:52 PM
Xenon Pharmaceuticals Inc. (NASDAQ:XENE) Q4 2023 Earnings Call TranscriptXenon Pharmaceuticals Inc. (NASDAQ:XENE) Q4 2023 Earnings Call Transcript
finance.yahoo.com - March 2 at 9:52 AM
Xenon Pharmaceuticals Inc.: Xenon Pharmaceuticals Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Corporate UpdateXenon Pharmaceuticals Inc.: Xenon Pharmaceuticals Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Corporate Update
finanznachrichten.de - March 1 at 2:30 PM
Xenon (XENE) Q4 Earnings Top Estimates, Pipeline in FocusXenon (XENE) Q4 Earnings Top Estimates, Pipeline in Focus
zacks.com - March 1 at 9:36 AM
Buy Rating Justified by Xenon Pharmaceuticals’ Advanced Epilepsy Program and Growth Prospects in NeuroscienceBuy Rating Justified by Xenon Pharmaceuticals’ Advanced Epilepsy Program and Growth Prospects in Neuroscience
markets.businessinsider.com - March 1 at 9:23 AM

New MarketBeat Followers Over Time

Media Sentiment Over Time

Top Headlines

All Headlines

Company Descriptions

Axon Enterprise logo

Axon Enterprise

NASDAQ:AXON
Axon Enterprise, Inc. develops, manufactures, and sells conducted energy devices (CEDs) under the TASER brand in the United States and internationally. It operates through two segments, Software and Sensors, and TASER. The company also offers hardware and cloud-based software solutions that enable law enforcement to capture, securely store, manage, share, and analyze video and other digital evidence. Its products include axon officer safety plan; taser 10, taser7, taser X26P, taser X2, taser 7 CQ, and civilian series; cameras, such as axon body, axon flex, axon fleet, axon air, axon signal sidearm, axon signal vehicle, axon interview, and axon interview portable kit; software, including axon records, evidence, standards, commander, performance, auto-transcribe, justice, investigate, respond, and justice, my90, and redaction assistant; mobile applications, and training services, as well as hardware extended warranties; and Axon docks, cartridges, and batteries. The company sells its products through its direct sales, distribution partners, online store, and third-party resellers. Axon Enterprise, Inc. has a strategic partnership with Fusus, Inc. to expand bility to aggregate live video, data, and sensor feeds. It serves law enforcement, federal, correction, fire, EMS, campus, justice healthcare, retail, private security, and personal safety industries. The company was formerly known as TASER International, Inc. and changed its name to Axon Enterprise, Inc. in April 2017. Axon Enterprise, Inc. was incorporated in 1993 and is headquartered in Scottsdale, Arizona.
Atreca logo

Atreca

NASDAQ:BCEL
Atreca, Inc., a clinical-stage biopharmaceutical company, discovers and develops antibody-based immunotherapeutics to treat a range of solid tumor types. Its lead product candidate is ATRC-101, a monoclonal antibody with a novel mechanism of action and target derived from an antibody identified using its discovery platform. The company's ATRC-101 product candidate reacts in vitro with a majority of human ovarian, non-small cell lung, colorectal, and breast cancer samples from multiple patients; and ATRC-501/MAM01, that targets the circumsporozoite protein of Plasmodium falciparum for the treatment of malaria. Its products in pre-clinical stage include APN-497444, an antibody drug conjugate (ADC) against a novel tumor glycan target; and APN-346958, a CD3 bispecific T-cell engager against an RNA-binding protein target. It has a collaboration and license agreement with Xencor, Inc. for research, development, and commercialization of novel CD3 bispecific antibodies in oncology; licensing agreement with the Bill & Melinda Gates Medical Research Institute for the development and commercialization of MAM01/ATRC-501 for the prevention of malaria. The company was incorporated in 2010 and is based in San Carlos, California.
Clovis Oncology logo

Clovis Oncology

NASDAQ:CLVS
Clovis Oncology, Inc, a biopharmaceutical company, focuses on acquiring, developing, and commercializing anti-cancer agents in the United States, Europe, and internationally. Its commercial product includes Rubraca (rucaparib) tablet, a small molecule poly ADP-ribose polymerase inhibitor, used as monotherapy for the treatment of patients with deleterious BRCA mutation associated advanced ovarian cancer, who have been treated with two or more chemotherapies, and selected for therapy by an FDA-approved companion diagnostic for Rubraca. As of 4/6/18, Rubraca® (rucaparib) is also approved by the FDA for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy. FDA granted regular approval for Rubraca in this second, broader and earlier-line indication on a priority review timeline based on positive data from the phase 3 ARIEL3 clinical trial. Biomarker testing is not required for patients to be prescribed Rubraca in this maintenance treatment indication.
Ovid Therapeutics logo

Ovid Therapeutics

NASDAQ:OVID
Ovid Therapeutics Inc., a biopharmaceutical company, engages in the development of impactful medicines for patients and families with epilepsies and seizure-related neurological disorders in the United States. The company is developing soticlestat, a novel cholesterol 24 hydroxylase inhibitor, which is in Phase 3 clinical trials for the potential treatment of patients with resistant epilepsies; OV329, a GABA aminotransferase inhibitor which is in Phase 1 clinical trials for the treatment of seizures associated with tuberous sclerosis complex and infantile spasms; and OV350, a small molecule direct activator of the KCC2 transporter, which is in Phase 1 clinical trials for treating epilepsies. It also develops OV815, that focuses on the mutations associated with KIF1A-associated neurological disorder (KAND); OV888 (GV101), a highly selective rock2 inhibitor which is in Phase 1 double-blind multiple-ascending dose trial; OV825, has advanced to potential candidate lead identification for the rare neurodevelopmental condition HNRNPH2 (Bain Syndrome); and OV882, a short hairpin RNA gene therapy for the treatment of Angelman syndrome. The company has license and collaboration agreements with Healx, AstraZeneca AB, H. Lundbeck A/S, Northwestern University, and Graviton, as well as Marinus Pharmaceuticals, Inc. The company was incorporated in 2014 and is headquartered in New York, New York.
Xenon Pharmaceuticals logo

Xenon Pharmaceuticals

NASDAQ:XENE
Xenon Pharmaceuticals Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics to treat patients with neurological disorders in Canada. Its clinical development pipeline includes XEN496, a Kv7 potassium channel opener that is Phase III clinical trials for the treatment of KCNQ2 developmental and epileptic encephalopathy; and XEN1101, a Kv7 potassium channel opener, which is in Phase II clinical trial for the treatment of epilepsy and other neurological disorders. The company's product candidates also comprise NBI-921352, a selective Nav1.6 sodium channel inhibitor that is in Phase II clinical trials for the treatment of SCN8A developmental and epileptic encephalopathy, and other indications, including adult focal epilepsy. It has a license and collaboration agreement with the Neurocrine Biosciences, Inc. to develop treatments for epilepsy. The company was incorporated in 1996 and is headquartered in Burnaby, Canada.