S&P 500   5,022.21
DOW   37,753.31
QQQ   425.84
ASML Fires Warning Shot For Tech Investors
Checking in with 5 Bitcoin Stocks Ahead of Bitcoin's Halving
Lululemon’s P/E Is Back to 2017 Levels: Should You Buy the Dip?
Abbott Laboratories Outlook is Healthy: Buy the Dip
Closing prices for crude oil, gold and other commodities
Stock market today: World shares are mixed after a tech-led retreat on Wall Street
Prologis Stock Leading U.S. Logistics Boom
S&P 500   5,022.21
DOW   37,753.31
QQQ   425.84
ASML Fires Warning Shot For Tech Investors
Checking in with 5 Bitcoin Stocks Ahead of Bitcoin's Halving
Lululemon’s P/E Is Back to 2017 Levels: Should You Buy the Dip?
Abbott Laboratories Outlook is Healthy: Buy the Dip
Closing prices for crude oil, gold and other commodities
Stock market today: World shares are mixed after a tech-led retreat on Wall Street
Prologis Stock Leading U.S. Logistics Boom
S&P 500   5,022.21
DOW   37,753.31
QQQ   425.84
ASML Fires Warning Shot For Tech Investors
Checking in with 5 Bitcoin Stocks Ahead of Bitcoin's Halving
Lululemon’s P/E Is Back to 2017 Levels: Should You Buy the Dip?
Abbott Laboratories Outlook is Healthy: Buy the Dip
Closing prices for crude oil, gold and other commodities
Stock market today: World shares are mixed after a tech-led retreat on Wall Street
Prologis Stock Leading U.S. Logistics Boom
S&P 500   5,022.21
DOW   37,753.31
QQQ   425.84
ASML Fires Warning Shot For Tech Investors
Checking in with 5 Bitcoin Stocks Ahead of Bitcoin's Halving
Lululemon’s P/E Is Back to 2017 Levels: Should You Buy the Dip?
Abbott Laboratories Outlook is Healthy: Buy the Dip
Closing prices for crude oil, gold and other commodities
Stock market today: World shares are mixed after a tech-led retreat on Wall Street
Prologis Stock Leading U.S. Logistics Boom

Compare Stocks

Comparative Price Performance Over Time

Compare Stocks - Price & Volume

CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
$21.47
+0.6%
$23.38
$13.36
$27.50
$574.54M-0.3312,725 shs297,067 shs
Phibro Animal Health Co. stock logo
PAHC
Phibro Animal Health
$12.87
-0.9%
$12.67
$9.40
$15.98
$526.13M0.75105,474 shs99,784 shs
Repare Therapeutics Inc. stock logo
RPTX
Repare Therapeutics
$3.21
-3.9%
$5.49
$3.08
$13.85
$123.58M0.56102,733 shs79,291 shs
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
$7.46
+1.5%
$9.62
$2.47
$13.03
$784.38M0.83663,572 shs475,262 shs
Zymeworks Inc. stock logo
ZYME
Zymeworks
$8.85
-0.9%
$10.86
$6.01
$13.14
$630.17M1.14465,004 shs547,242 shs
13 Stocks Institutional Investors Won't Stop Buying Cover

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Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
+0.61%-3.16%-7.34%-9.37%-3.46%
Phibro Animal Health Co. stock logo
PAHC
Phibro Animal Health
-0.92%-2.72%+3.12%+13.59%-17.97%
Repare Therapeutics Inc. stock logo
RPTX
Repare Therapeutics
-3.89%-18.53%-37.91%-47.55%-64.73%
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
+1.50%-0.13%-11.08%-31.87%+101.08%
Zymeworks Inc. stock logo
ZYME
Zymeworks
-0.90%-2.64%-17.37%-10.24%-11.32%

MarketRank™

CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
2.4988 of 5 stars
4.40.00.00.02.62.50.6
Phibro Animal Health Co. stock logo
PAHC
Phibro Animal Health
4.454 of 5 stars
2.04.02.51.13.93.32.5
Repare Therapeutics Inc. stock logo
RPTX
Repare Therapeutics
1.923 of 5 stars
3.52.00.00.00.04.20.6
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
1.8414 of 5 stars
3.50.00.00.03.42.50.6
Zymeworks Inc. stock logo
ZYME
Zymeworks
0.8606 of 5 stars
3.00.00.00.01.01.70.6

Analyst Ratings

CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
2.78
Moderate Buy$46.22115.29% Upside
Phibro Animal Health Co. stock logo
PAHC
Phibro Animal Health
2.00
Hold$15.3319.14% Upside
Repare Therapeutics Inc. stock logo
RPTX
Repare Therapeutics
3.00
Buy$17.33439.98% Upside
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
3.00
Buy$17.25131.23% Upside
Zymeworks Inc. stock logo
ZYME
Zymeworks
2.00
Hold$15.0069.49% Upside

Current Analyst Ratings

Latest PAHC, ZYME, RPTX, TNGX, and ANAB Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
4/16/2024
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
Leerink Partnrs
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOutperform
4/16/2024
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
SVB Leerink
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOutperform$47.00
4/11/2024
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
Wells Fargo & Company
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOverweight$56.00
4/4/2024
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
Cantor Fitzgerald
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOverweight
4/1/2024
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
JPMorgan Chase & Co.
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetNeutral ➝ Neutral$30.00 ➝ $28.00
3/20/2024
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetBuy ➝ Buy$16.00 ➝ $17.00
3/18/2024
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
Wedbush
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOutperform$18.00
3/12/2024
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
Wedbush
Subscribe to MarketBeat All Access for the recommendation accuracy rating
UpgradeNeutral ➝ Outperform$20.00 ➝ $34.00
2/26/2024
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
BTIG Research
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageBuy$55.00
2/21/2024
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
Stifel Nicolaus
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageBuy$50.00
2/21/2024
Repare Therapeutics Inc. stock logo
RPTX
Repare Therapeutics
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingBuy ➝ Buy$10.00
(Data available from 4/18/2021 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Sales & Book Value

CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
$17.16M33.48N/AN/A$3.32 per share6.47
Phibro Animal Health Co. stock logo
PAHC
Phibro Animal Health
$977.90M0.53$2.05 per share6.28$6.97 per share1.85
Repare Therapeutics Inc. stock logo
RPTX
Repare Therapeutics
$51.13M2.32N/AN/A$5.03 per share0.64
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
$36.53M21.80N/AN/A$2.48 per share3.01
Zymeworks Inc. stock logo
ZYME
Zymeworks
$76.01M8.22N/AN/A$6.63 per share1.33

Profitability & Earnings

CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
-$163.62M-$6.08N/AN/AN/A-953.66%-119.42%-32.58%5/9/2024 (Estimated)
Phibro Animal Health Co. stock logo
PAHC
Phibro Animal Health
$32.61M$0.3635.7510.644.811.51%16.67%4.73%5/1/2024 (Estimated)
Repare Therapeutics Inc. stock logo
RPTX
Repare Therapeutics
-$93.80M-$2.23N/AN/AN/A-183.43%-39.82%-31.84%5/14/2024 (Estimated)
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
-$101.74M-$1.10N/AN/AN/A-278.55%-41.96%-25.22%5/14/2024 (Estimated)
Zymeworks Inc. stock logo
ZYME
Zymeworks
-$118.67M-$1.74N/AN/AN/A-156.12%-26.20%-20.29%5/2/2024 (Confirmed)

Latest PAHC, ZYME, RPTX, TNGX, and ANAB Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
5/2/2024N/A
Zymeworks Inc. stock logo
ZYME
Zymeworks
-$0.31N/A+$0.31N/AN/AN/A  
3/18/2024Q4 2023
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
-$0.28-$0.32-$0.04-$0.32$7.86 million$5.43 million
3/11/2024Q4 2023
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
-$1.74-$1.59+$0.15-$1.59$3.28 million$9.01 million
3/6/2024Q4 2023
Zymeworks Inc. stock logo
ZYME
Zymeworks
-$0.39-$0.20+$0.19-$0.20$18.32 million$16.93 million
2/28/2024Q4 2023
Repare Therapeutics Inc. stock logo
RPTX
Repare Therapeutics
-$0.56-$0.67-$0.11-$0.67$15.92 million$13.05 million
2/7/2024Q2 2024
Phibro Animal Health Co. stock logo
PAHC
Phibro Animal Health
$0.27$0.33+$0.06$0.63$242.91 million$249.90 million

Dividends

CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
N/AN/AN/AN/AN/A
Phibro Animal Health Co. stock logo
PAHC
Phibro Animal Health
$0.483.73%N/A133.33%N/A
Repare Therapeutics Inc. stock logo
RPTX
Repare Therapeutics
N/AN/AN/AN/AN/A
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
N/AN/AN/AN/AN/A
Zymeworks Inc. stock logo
ZYME
Zymeworks
N/AN/AN/AN/AN/A

Latest PAHC, ZYME, RPTX, TNGX, and ANAB Dividends

AnnouncementCompanyPeriodAmountYieldEx-Dividend DateRecord DatePayable Date
2/6/2024
Phibro Animal Health Co. stock logo
PAHC
Phibro Animal Health
Quarterly$0.124.5%3/5/20243/6/20243/27/2024
(Data available from 1/1/2013 forward)

Debt

CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
N/A
10.87
10.87
Phibro Animal Health Co. stock logo
PAHC
Phibro Animal Health
1.66
3.12
1.60
Repare Therapeutics Inc. stock logo
RPTX
Repare Therapeutics
N/A
6.24
6.24
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
N/A
7.54
7.54
Zymeworks Inc. stock logo
ZYME
Zymeworks
N/A
7.41
7.41

Ownership

Institutional Ownership

CompanyInstitutional Ownership
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
N/A
Phibro Animal Health Co. stock logo
PAHC
Phibro Animal Health
99.34%
Repare Therapeutics Inc. stock logo
RPTX
Repare Therapeutics
85.09%
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
78.99%
Zymeworks Inc. stock logo
ZYME
Zymeworks
92.89%

Insider Ownership

CompanyInsider Ownership
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
35.50%
Phibro Animal Health Co. stock logo
PAHC
Phibro Animal Health
50.06%
Repare Therapeutics Inc. stock logo
RPTX
Repare Therapeutics
28.50%
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
6.20%
Zymeworks Inc. stock logo
ZYME
Zymeworks
1.22%

Miscellaneous

CompanyEmployeesShares OutstandingFree FloatOptionable
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
11726.76 million17.26 millionOptionable
Phibro Animal Health Co. stock logo
PAHC
Phibro Animal Health
1,92040.50 million20.23 millionOptionable
Repare Therapeutics Inc. stock logo
RPTX
Repare Therapeutics
17937.00 million26.46 millionOptionable
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
140106.72 million100.10 millionOptionable
Zymeworks Inc. stock logo
ZYME
Zymeworks
27270.57 million69.71 millionOptionable

PAHC, ZYME, RPTX, TNGX, and ANAB Headlines

SourceHeadline
Levi & Korsinsky Reminds Shareholders of an Investigation into Zymeworks Inc. (ZYME) Regarding Potential Securities Fraud AllegationsLevi & Korsinsky Reminds Shareholders of an Investigation into Zymeworks Inc. (ZYME) Regarding Potential Securities Fraud Allegations
markets.businessinsider.com - April 16 at 6:55 PM
Maintaining Hold on Zymeworks: ZW191’s Potential Amidst Competitive and Regulatory HurdlesMaintaining Hold on Zymeworks: ZW191’s Potential Amidst Competitive and Regulatory Hurdles
markets.businessinsider.com - April 12 at 6:42 PM
Zymeworks Inc. INVESTIGATION: Levi & Korsinsky Investigates Potential Securities Fraud by Zymeworks (ZYME)Zymeworks Inc. INVESTIGATION: Levi & Korsinsky Investigates Potential Securities Fraud by Zymeworks (ZYME)
accesswire.com - April 12 at 10:05 AM
Levi & Korsinsky Reminds Zymeworks Investors of the Ongoing Investigation into Potential Violations of Securities Laws - ZYMELevi & Korsinsky Reminds Zymeworks Investors of the Ongoing Investigation into Potential Violations of Securities Laws - ZYME
accesswire.com - April 12 at 10:00 AM
SHAREHOLDER ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Zymeworks Inc. - ZYMESHAREHOLDER ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Zymeworks Inc. - ZYME
prnewswire.com - April 12 at 9:30 AM
Zymeworks Inc. Investigation Ongoing: Contact Levi & Korsinsky About Potential Securities Fraud Allegations - ZYMEZymeworks Inc. Investigation Ongoing: Contact Levi & Korsinsky About Potential Securities Fraud Allegations - ZYME
accesswire.com - April 12 at 7:30 AM
Zymeworks To Report First Quarter 2024 Financial Results and Host Conference Call on May 2, 2024Zymeworks To Report First Quarter 2024 Financial Results and Host Conference Call on May 2, 2024
globenewswire.com - April 11 at 6:00 AM
Did Zymeworks Inc. Mislead Investors? Shareholder Rights Advocates at Levi & Korsinsky Investigate - ZYMEDid Zymeworks Inc. Mislead Investors? Shareholder Rights Advocates at Levi & Korsinsky Investigate - ZYME
accesswire.com - April 10 at 4:45 PM
Zymeworks (ZYME) Loses -13.41% in 4 Weeks, Heres Why a Trend Reversal May be Around the CornerZymeworks (ZYME) Loses -13.41% in 4 Weeks, Here's Why a Trend Reversal May be Around the Corner
zacks.com - April 10 at 10:36 AM
Zymeworks (NYSE:ZYME) Trading Down 2.6%Zymeworks (NYSE:ZYME) Trading Down 2.6%
marketbeat.com - April 9 at 11:46 AM
Zymeworks Inc. Investigated by Shareholder Rights Advocates – Investors Should Contact Levi & Korsinsky Regarding Potential Securities Law Violations - ZYMEZymeworks Inc. Investigated by Shareholder Rights Advocates – Investors Should Contact Levi & Korsinsky Regarding Potential Securities Law Violations - ZYME
accesswire.com - April 8 at 4:00 PM
Opinion: The Next Generation of ADCs Will Improve Cancer TreatmentOpinion: The Next Generation of ADCs Will Improve Cancer Treatment
biospace.com - April 8 at 7:05 AM
Zymeworks Presents New Data from Multiple Preclinical Development Programs at 2024 American Association for Cancer Research Annual MeetingZymeworks Presents New Data from Multiple Preclinical Development Programs at 2024 American Association for Cancer Research Annual Meeting
globenewswire.com - April 8 at 6:00 AM
Zymeworks Inc. Investigation Ongoing: Contact Levi & Korsinsky About Potential Securities Fraud Allegations - ZYMEZymeworks Inc. Investigation Ongoing: Contact Levi & Korsinsky About Potential Securities Fraud Allegations - ZYME
accesswire.com - April 4 at 8:45 PM
SHAREHOLDER ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Zymeworks Inc. - ZYMESHAREHOLDER ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Zymeworks Inc. - ZYME
prnewswire.com - April 4 at 6:18 PM
Kirby McInerney LLP Announces Investigation of Shareholder Claims Against Zymeworks Inc. (ZYME)Kirby McInerney LLP Announces Investigation of Shareholder Claims Against Zymeworks Inc. (ZYME)
morningstar.com - April 4 at 7:39 AM
Zymeworks Inc. Investigation Ongoing: Contact Levi & Korsinsky About Potential Securities Fraud Allegations - ZYMEZymeworks Inc. Investigation Ongoing: Contact Levi & Korsinsky About Potential Securities Fraud Allegations - ZYME
accesswire.com - April 3 at 9:30 PM
Zymeworks Inc. Investigated Regarding Potential Securities Law Violations - Contact Levi & Korsinsky for Details - ZYMEZymeworks Inc. Investigated Regarding Potential Securities Law Violations - Contact Levi & Korsinsky for Details - ZYME
accesswire.com - April 3 at 8:00 PM
Zymeworks re­moves CFO; Gilead ex­tends Nurix dealZymeworks re­moves CFO; Gilead ex­tends Nurix deal
endpts.com - April 3 at 4:37 PM
SHAREHOLDER ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Zymeworks Inc. - ZYMESHAREHOLDER ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Zymeworks Inc. - ZYME
stockhouse.com - April 2 at 5:54 PM
Zymeworks (NYSE:ZYME) Stock Price Down 6.7%Zymeworks (NYSE:ZYME) Stock Price Down 6.7%
marketbeat.com - April 1 at 3:29 PM
Zymeworks Inc. (NYSE:ZYME) Shares Purchased by Wellington Management Group LLPZymeworks Inc. (NYSE:ZYME) Shares Purchased by Wellington Management Group LLP
marketbeat.com - March 29 at 4:09 AM
Zymeworks Inc.: Zymeworks Announces Appointment of Dr. Neil Gallagher to its Board of DirectorsZymeworks Inc.: Zymeworks Announces Appointment of Dr. Neil Gallagher to its Board of Directors
finanznachrichten.de - March 28 at 10:14 AM
Zymeworks Announces Appointment of Dr. Neil Gallagher to its Board of DirectorsZymeworks Announces Appointment of Dr. Neil Gallagher to its Board of Directors
globenewswire.com - March 28 at 6:00 AM

New MarketBeat Followers Over Time

Media Sentiment Over Time

Company Descriptions

AnaptysBio logo

AnaptysBio

NASDAQ:ANAB
AnaptysBio, Inc., a clinical-stage biotechnology company, focuses in delivering immunology therapeutics. Its products include Rosnilimab, an IgG1 antibody that targets PD-1+ T cells, resulting in their agonism or depletion, broadly impacting pathogenic drivers of autoimmune and inflammatory diseases; and ANB032, a non-depleting antibody that binds to the BTLA checkpoint receptor and inhibits activated T cell proliferation; ANB033, a novel anti-CD122 antagonist antibody that targets the shared common beta subunit of the receptors for IL-15 and IL-2; ANB101, a BDCA2 modulator antibody that specifically targets plasmacytoid dendritic cells (pDCs); and Imsidolimab, an antibody that inhibits the interleukin-36 receptor, which is in the Phase 3 development for the treatment of generalized pustular psoriasis. The company also focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations. It has a collaboration and license agreement with GlaxoSmithKline, Inc. The company was formerly known as Anaptys Biosciences, Inc. and changed its name to AnaptysBio, Inc. in July 2006. AnaptysBio, Inc. was incorporated in 2005 and is based in San Diego, California.
Phibro Animal Health logo

Phibro Animal Health

NASDAQ:PAHC
Phibro Animal Health Corporation operates as an animal health and mineral nutrition company in the United States, Israel, Brazil, Ireland, and internationally. It operates through three segments: Animal Health, Mineral Nutrition, and Performance Products. The company develops, manufactures, and markets various products for food and companion animals including poultry, swine, beef and dairy cattle, aquaculture, and dogs. It also offers animal health products, such as antibacterials, anticoccidials, nutritional specialty, and vaccines and vaccine adjuvants for animal's health and performance, food safety, and animal welfare; and engages in development, manufacturing, and marketing of microbial and bioproducts for various applications serving animal health and nutrition, industrial, environmental, and agricultural customers. In addition, the company develops, manufactures, and markets conventionally licensed and autogenous vaccine products, as well as adjuvants for animal vaccine manufacturers. Further, it provides formulations and concentrations of trace minerals, such as zinc, manganese, copper, iron, and other compounds to fortify the daily feed requirements of their livestock's diets and maintain optimal balance of trace elements in animals. Additionally, the company offers specialty ingredients for personal care, industrial chemical, and chemical catalyst industries. It sells its animal health and mineral nutrition products through local sales offices to integrated poultry, swine, and cattle integrators, as well as through commercial animal feed manufacturers, wholesalers, and distributors. The company was formerly known as Philipp Brothers Chemicals, Inc. and changed its name to Phibro Animal Health Corporation in July 2003. Phibro Animal Health Corporation was founded in 1946 and is headquartered in Teaneck, New Jersey.
Repare Therapeutics logo

Repare Therapeutics

NASDAQ:RPTX
Repare Therapeutics Inc., a clinical-stage precision oncology company, engages in the discovery and development of therapeutics by using its synthetic lethality approach in Canada and the United States. It uses its SNIPRx, a proprietary, genome-wide, and CRISPR-enabled platform, to discover, validate, and build a pipeline of SL-based therapeutics that focuses on genomic instability, including DNA damage repair. The company's lead product candidate is Camonsertib (RP-3500), an oral small molecule inhibitor under Phase ½ development for the treatment of solid tumors with specific DNA damage repair-related genomic alterations. It is also developing Lunresertib (RP-6306), a PKMYT1 Inhibitor, which is under Phase 1 clinical trial for tumors with genetic alterations characterized by CCNE1 amplification; RP-1664, an oral PLK4 inhibitor, under Phase 1 clinical trial designed to harness the synthetic lethal relationship with TRIM37 amplification or overexpression in solid tumors; and RP-3467, a polymerase theta adenosinetriphosphatase (ATPase) inhibitor, a SL target associated with BRCA mutations and other genomic alterations. The company has license and collaboration agreement with Hoffmann-La Roche Inc. and F. Hoffmann-La Roche Ltd; Bristol-Myers Squibb Company; New York University; and Ono Pharmaceutical Co., as well as a clinical study and collaboration agreement with Debiopharm to explore the synthetic lethal combination of PKMYT1 and WEE1 inhibition in cancer. Repare Therapeutics Inc. was incorporated in 2016 and is headquartered in Montréal, Canada.
Tango Therapeutics logo

Tango Therapeutics

NASDAQ:TNGX
Tango Therapeutics, Inc., a biotechnology company, discovers and develops drugs for the treatment of cancer. Its lead program is TNG908, a synthetic lethal small molecule inhibitor of protein arginine methyltransferase 5 that is being developed as a treatment for cancers with methylthioadenosine phosphorylase deletions. The company develops TNG462, an oral small molecule methylthioadenosine-cooperative inhibitor for the treatment for cancers with methylthioadenosine phosphorylase deletions; TNG260, a co-repressor of repressor element-1 silencing transcription -selective inhibitor; TNG348, an ubiquitin-specific protease 1 inhibitor to treat patients with BRCA1 or BRCA2-mutant cancers; and Target 3 for STK11-mutant cancers. It has a strategic collaboration with Gilead Sciences, Inc. for the discovery, development, and commercialization of a pipeline of therapies for patients with cancer. Tango Therapeutics, Inc. was founded in 2017 and is headquartered in Boston, Massachusetts.
Zymeworks logo

Zymeworks

NYSE:ZYME
Zymeworks Inc., a clinical-stage biopharmaceutical company, discovers, develops, and commercializes biotherapeutics for the treatment of cancer. The company's lead product candidates include zanidatamab, a human epidermal growth factor receptor 2 (HER2) that is in Phase 1, Phase 2, and Phase 3 clinical trials, including certain ongoing pivotal clinical trials; and zanidatamab zovodotin, a HER2 -targeted antibody-drug conjugate that is in Phase 2 clinical trial for the treatment of advanced or metastatic HER2-expressing tumors. It also develops a pipeline of preclinical product candidates and discovery-stage programs in oncology, including immuno-oncology agents and other therapeutic areas. Zymeworks Inc. has strategic partnerships and collaborations with BeiGene, Ltd.; Celgene Corporation; Celgene Alpine Investment Co. LLC; GlaxoSmithKline Intellectual Property Development Limited; Daiichi Sankyo Co., Ltd.; Janssen Biotech, Inc.; LEO Pharma A/S; Iconic Therapeutics, Inc.; Merck Sharp & Dohme Research GmbH; and Atreca, Inc. Zymeworks Inc. was incorporated in 2003 and is based in Middletown, Delaware.