Compare Stocks

Comparative Price Performance Over Time

Compare Stocks - Price & Volume

CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Aytu BioPharma, Inc. stock logo
AYTU
Aytu BioPharma
$2.78
-0.4%
$3.02
$1.38
$3.50
$15.49M-1.2119,358 shs6,642 shs
Leap Therapeutics, Inc. stock logo
LPTX
Leap Therapeutics
$3.21
+14.6%
$2.75
$1.24
$10.20
$71.68M0.57526,465 shs328,679 shs
Otonomy, Inc. stock logo
OTIC
Otonomy
$0.01
$0.06
$0.01
$2.54
$582K1.54937,525 shsN/A
Synlogic, Inc. stock logo
SYBX
Synlogic
$1.84
-1.6%
$1.82
$1.55
$10.20
$21.78M1.0931,291 shs21,725 shs
Zynerba Pharmaceuticals, Inc. stock logo
ZYNE
Zynerba Pharmaceuticals
$1.30
+2.4%
$1.30
$0.25
$1.40
$70.12M1.32515,333 shs862,700 shs
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Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Aytu BioPharma, Inc. stock logo
AYTU
Aytu BioPharma
-0.36%+4.12%-8.55%+1.09%+2.96%
Leap Therapeutics, Inc. stock logo
LPTX
Leap Therapeutics
+14.64%+7.00%+27.38%+12.63%-12.84%
Otonomy, Inc. stock logo
OTIC
Otonomy
0.00%0.00%0.00%0.00%0.00%
Synlogic, Inc. stock logo
SYBX
Synlogic
-1.60%+2.22%+2.22%-42.50%-81.08%
Zynerba Pharmaceuticals, Inc. stock logo
ZYNE
Zynerba Pharmaceuticals
0.00%0.00%0.00%0.00%+225.00%

MarketRank™

CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Aytu BioPharma, Inc. stock logo
AYTU
Aytu BioPharma
2.4436 of 5 stars
3.51.00.03.40.00.00.6
Leap Therapeutics, Inc. stock logo
LPTX
Leap Therapeutics
1.0726 of 5 stars
3.52.00.00.00.60.80.6
Otonomy, Inc. stock logo
OTIC
Otonomy
N/AN/AN/AN/AN/AN/AN/AN/A
Synlogic, Inc. stock logo
SYBX
Synlogic
1.9644 of 5 stars
3.13.00.00.01.82.50.6
Zynerba Pharmaceuticals, Inc. stock logo
ZYNE
Zynerba Pharmaceuticals
N/AN/AN/AN/AN/AN/AN/AN/A

Analyst Ratings

CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Aytu BioPharma, Inc. stock logo
AYTU
Aytu BioPharma
3.00
Buy$5.0079.86% Upside
Leap Therapeutics, Inc. stock logo
LPTX
Leap Therapeutics
3.00
Buy$11.38254.36% Upside
Otonomy, Inc. stock logo
OTIC
Otonomy
N/AN/AN/AN/A
Synlogic, Inc. stock logo
SYBX
Synlogic
2.20
Hold$65.003,432.61% Upside
Zynerba Pharmaceuticals, Inc. stock logo
ZYNE
Zynerba Pharmaceuticals
2.00
Hold$1.11-14.62% Downside

Current Analyst Ratings

Latest SYBX, LPTX, OTIC, ZYNE, and AYTU Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
3/20/2024
Synlogic, Inc. stock logo
SYBX
Synlogic
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
UpgradeSell ➝ Neutral
3/19/2024
Leap Therapeutics, Inc. stock logo
LPTX
Leap Therapeutics
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingBuy ➝ Buy$7.00
3/19/2024
Leap Therapeutics, Inc. stock logo
LPTX
Leap Therapeutics
Robert W. Baird
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetOutperform ➝ Outperform$11.00 ➝ $9.00
2/9/2024
Synlogic, Inc. stock logo
SYBX
Synlogic
Leerink Partnrs
Subscribe to MarketBeat All Access for the recommendation accuracy rating
DowngradeOutperform ➝ Market Perform
2/9/2024
Synlogic, Inc. stock logo
SYBX
Synlogic
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
DowngradeBuy ➝ Sell
2/9/2024
Synlogic, Inc. stock logo
SYBX
Synlogic
SVB Leerink
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOutperform ➝ Market Perform
2/9/2024
Synlogic, Inc. stock logo
SYBX
Synlogic
Chardan Capital
Subscribe to MarketBeat All Access for the recommendation accuracy rating
DowngradeBuy ➝ Neutral
(Data available from 4/23/2021 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Sales & Book Value

CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Aytu BioPharma, Inc. stock logo
AYTU
Aytu BioPharma
$107.40M0.14$0.98 per share2.83$10.41 per share0.27
Leap Therapeutics, Inc. stock logo
LPTX
Leap Therapeutics
$1.50M54.78N/AN/A$2.35 per share1.37
Otonomy, Inc. stock logo
OTIC
Otonomy
$130K4.48N/AN/A$0.97 per share0.01
Synlogic, Inc. stock logo
SYBX
Synlogic
$3.37M6.36N/AN/A$4.64 per share0.40
Zynerba Pharmaceuticals, Inc. stock logo
ZYNE
Zynerba Pharmaceuticals
N/AN/AN/AN/A$1.01 per shareN/A

Profitability & Earnings

CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Aytu BioPharma, Inc. stock logo
AYTU
Aytu BioPharma
-$17.05M-$4.04N/AN/A-18.27%-41.00%-10.87%5/9/2024 (Estimated)
Leap Therapeutics, Inc. stock logo
LPTX
Leap Therapeutics
-$81.41M-$5.08N/AN/AN/AN/A-133.17%-90.90%5/20/2024 (Estimated)
Otonomy, Inc. stock logo
OTIC
Otonomy
-$51.18M-$0.77N/AN/AN/A-137.86%-68.50%N/A
Synlogic, Inc. stock logo
SYBX
Synlogic
-$57.28M-$10.88N/AN/AN/A-1,699.23%-109.34%-72.85%5/9/2024 (Estimated)
Zynerba Pharmaceuticals, Inc. stock logo
ZYNE
Zynerba Pharmaceuticals
-$35.04M-$0.80N/AN/AN/AN/A-90.03%-72.62%N/A

Latest SYBX, LPTX, OTIC, ZYNE, and AYTU Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
3/19/2024Q4 2023
Synlogic, Inc. stock logo
SYBX
Synlogic
-$1.11-$1.71-$0.60-$1.71$2.71 million$2.77 million
3/18/2024Q4 2023
Leap Therapeutics, Inc. stock logo
LPTX
Leap Therapeutics
-$0.56-$0.46+$0.10-$0.46N/AN/A
2/14/2024Q2 2024
Aytu BioPharma, Inc. stock logo
AYTU
Aytu BioPharma
N/A-$0.04-$0.04-$0.04N/A$22.93 million

Dividends

CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Aytu BioPharma, Inc. stock logo
AYTU
Aytu BioPharma
N/AN/AN/AN/AN/A
Leap Therapeutics, Inc. stock logo
LPTX
Leap Therapeutics
N/AN/AN/AN/AN/A
Otonomy, Inc. stock logo
OTIC
Otonomy
N/AN/AN/AN/AN/A
Synlogic, Inc. stock logo
SYBX
Synlogic
N/AN/AN/AN/AN/A
Zynerba Pharmaceuticals, Inc. stock logo
ZYNE
Zynerba Pharmaceuticals
N/AN/AN/AN/AN/A

Debt

CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Aytu BioPharma, Inc. stock logo
AYTU
Aytu BioPharma
0.46
1.11
0.91
Leap Therapeutics, Inc. stock logo
LPTX
Leap Therapeutics
N/A
5.64
5.64
Otonomy, Inc. stock logo
OTIC
Otonomy
N/A
1.74
1.74
Synlogic, Inc. stock logo
SYBX
Synlogic
N/A
2.45
2.45
Zynerba Pharmaceuticals, Inc. stock logo
ZYNE
Zynerba Pharmaceuticals
N/A
3.43
3.43

Ownership

Institutional Ownership

CompanyInstitutional Ownership
Aytu BioPharma, Inc. stock logo
AYTU
Aytu BioPharma
33.49%
Leap Therapeutics, Inc. stock logo
LPTX
Leap Therapeutics
30.46%
Otonomy, Inc. stock logo
OTIC
Otonomy
41.23%
Synlogic, Inc. stock logo
SYBX
Synlogic
63.40%
Zynerba Pharmaceuticals, Inc. stock logo
ZYNE
Zynerba Pharmaceuticals
11.23%

Insider Ownership

CompanyInsider Ownership
Aytu BioPharma, Inc. stock logo
AYTU
Aytu BioPharma
4.34%
Leap Therapeutics, Inc. stock logo
LPTX
Leap Therapeutics
11.30%
Otonomy, Inc. stock logo
OTIC
Otonomy
1.09%
Synlogic, Inc. stock logo
SYBX
Synlogic
8.01%
Zynerba Pharmaceuticals, Inc. stock logo
ZYNE
Zynerba Pharmaceuticals
13.04%

Miscellaneous

CompanyEmployeesShares OutstandingFree FloatOptionable
Aytu BioPharma, Inc. stock logo
AYTU
Aytu BioPharma
1505.57 million5.33 millionNot Optionable
Leap Therapeutics, Inc. stock logo
LPTX
Leap Therapeutics
5425.60 million22.71 millionOptionable
Otonomy, Inc. stock logo
OTIC
Otonomy
5168.53 million67.78 millionOptionable
Synlogic, Inc. stock logo
SYBX
Synlogic
611.65 million10.71 millionOptionable
Zynerba Pharmaceuticals, Inc. stock logo
ZYNE
Zynerba Pharmaceuticals
2553.94 million46.91 millionOptionable

SYBX, LPTX, OTIC, ZYNE, and AYTU Headlines

SourceHeadline
Harmony Biosciences Reports Strong Third Quarter 2023 Financial ResultsHarmony Biosciences Reports Strong Third Quarter 2023 Financial Results
finance.yahoo.com - October 31 at 7:57 AM
Why Shares of Harmony Bioscience Are Falling on FridayWhy Shares of Harmony Bioscience Are Falling on Friday
fool.com - October 13 at 12:59 PM
New Possibilities For Cannabinoid Treatments: Acquisition To Transform Neuropsychiatric Disorder TherapiesNew Possibilities For Cannabinoid Treatments: Acquisition To Transform Neuropsychiatric Disorder Therapies
markets.businessinsider.com - October 11 at 9:47 AM
HARMONY BIOSCIENCES COMPLETES ACQUISITION OF ZYNERBA PHARMACEUTICALS AND EXPANDS PIPELINEHARMONY BIOSCIENCES COMPLETES ACQUISITION OF ZYNERBA PHARMACEUTICALS AND EXPANDS PIPELINE
finance.yahoo.com - October 11 at 9:47 AM
H.C. Wainwright analysts reiterates a Buy rating for Zynerba Pharmaceuticals Inc (ZYNE)H.C. Wainwright analysts reiterates a Buy rating for Zynerba Pharmaceuticals Inc (ZYNE)
knoxdaily.com - October 10 at 1:59 PM
Analysts: ZYNE stock price target of $1.25 in 12 monthsAnalysts: ZYNE stock price target of $1.25 in 12 months
knoxdaily.com - October 5 at 6:47 PM
Important Information for Zynerba Pharmaceuticals Stockholders to Tender Shares for the Harmony Transaction: Process and InstructionsImportant Information for Zynerba Pharmaceuticals Stockholders to Tender Shares for the Harmony Transaction: Process and Instructions
finance.yahoo.com - October 4 at 7:33 PM
Examining the Potential Price Growth of Zynerba Pharmaceuticals Inc (ZYNE)Examining the Potential Price Growth of Zynerba Pharmaceuticals Inc (ZYNE)
knoxdaily.com - October 2 at 3:14 PM
20 Countries With Highest Rate of Epilepsy20 Countries With Highest Rate of Epilepsy
finance.yahoo.com - September 29 at 6:24 PM
Zynerba Pharmaceuticals Stockholders Reminded to Tender Shares Before 5:00 PM New York City Time, on Tuesday October 10, 2023Zynerba Pharmaceuticals Stockholders Reminded to Tender Shares Before 5:00 PM New York City Time, on Tuesday October 10, 2023
finance.yahoo.com - September 29 at 1:23 PM
Harmony Biosciences extends deadline for Zynerba shareholders on up to $200M dealHarmony Biosciences extends deadline for Zynerba shareholders on up to $200M deal
bizjournals.com - September 27 at 2:42 PM
Zynerba Pharmaceuticals Inc [ZYNE] Investment Appeal on the RiseZynerba Pharmaceuticals Inc [ZYNE] Investment Appeal on the Rise
knoxdaily.com - September 25 at 8:15 PM
Zynerba Pharmaceuticals Inc. (ZYNE) rating reiterates by H.C. WainwrightZynerba Pharmaceuticals Inc. (ZYNE) rating reiterates by H.C. Wainwright
knoxdaily.com - September 20 at 12:12 PM
Negative sentiment towards ZYNE reflected in surge in short interestNegative sentiment towards ZYNE reflected in surge in short interest
knoxdaily.com - September 15 at 8:27 PM
Insider Sell: President Terri Sebree Sells 12,401 Shares of Zynerba Pharmaceuticals IncInsider Sell: President Terri Sebree Sells 12,401 Shares of Zynerba Pharmaceuticals Inc
finance.yahoo.com - September 14 at 11:23 PM
Zynerba Pharmaceuticals Presents Positive Data from Phase 2 INSPIRE Trial in 22q11.2 Deletion Syndrome at The Society for the Study of Behavioural Phenotypes (SSBP) 25th International Research SymposiumZynerba Pharmaceuticals Presents Positive Data from Phase 2 INSPIRE Trial in 22q11.2 Deletion Syndrome at The Society for the Study of Behavioural Phenotypes (SSBP) 25th International Research Symposium
finance.yahoo.com - September 14 at 6:23 PM
Zynerba Pharmaceuticals Hit With Shareholder Suit in Pa. Over Allegedly Inadequate Proxy StatementZynerba Pharmaceuticals Hit With Shareholder Suit in Pa. Over Allegedly Inadequate Proxy Statement
law.com - September 11 at 4:04 PM
Positive sentiment towards ZYNE reflected in decline in short interestPositive sentiment towards ZYNE reflected in decline in short interest
knoxdaily.com - September 8 at 5:19 AM
SHAREHOLDER INVESTIGATION: Halper Sadeh LLC Investigates CTG, ZYNE, KLRSHAREHOLDER INVESTIGATION: Halper Sadeh LLC Investigates CTG, ZYNE, KLR
bakersfield.com - August 31 at 5:00 PM
HC Wainwright & Co. Downgrades Zynerba Pharmaceuticals (ZYNE)HC Wainwright & Co. Downgrades Zynerba Pharmaceuticals (ZYNE)
msn.com - August 16 at 4:20 AM
Harmony Makes Rare Disease Play with Potential $200M Zynerba BuyoutHarmony Makes Rare Disease Play with Potential $200M Zynerba Buyout
biospace.com - August 15 at 6:19 PM
Zynerba Pharma (NASDAQ: ZYNE) up 300% - The contingents are worth how much?Zynerba Pharma (NASDAQ: ZYNE) up 300% - The contingents are worth how much?
dhakatribune.com - August 15 at 6:19 PM
Is Zynerba Pharmaceuticals (NASDAQ:ZYNE) In A Good Position To Deliver On Growth Plans?Is Zynerba Pharmaceuticals (NASDAQ:ZYNE) In A Good Position To Deliver On Growth Plans?
finance.yahoo.com - August 15 at 6:19 PM
Zynerba Pharmaceuticals Shares Soar on Harmony Biosciences Deal >ZYNEZynerba Pharmaceuticals Shares Soar on Harmony Biosciences Deal >ZYNE
marketwatch.com - August 14 at 9:48 PM

New MarketBeat Followers Over Time

Media Sentiment Over Time

Top Headlines

All Headlines

Company Descriptions

Aytu BioPharma logo

Aytu BioPharma

NASDAQ:AYTU
Aytu Biopharma, Inc., a commercial-stage pharmaceutical company, focuses on commercializing novel therapeutics and consumer healthcare products the United States and internationally. The company operates through two segments: Rx segment and Consumer Health segment. The Rx segment offers prescription products for the treatment of attention deficit hyperactivity disorder (ADHD), including Adzenys XR-ODT for patients from six years and older, and Cotempla XR-ODT for patients from six to seventeen years old. The segment also provides pediatric prescription product portfolio comprising Karbinal ER, an extended-release carbinoxamine (antihistamine) suspension indicated to treat numerous allergic conditions for patients two years and above; and Poly-Vi-Flor and Tri-Vi-Flor complementary prescription fluoride-based multi-vitamin products containing combinations of fluoride and vitamins in liquid and chewable tablet form for infants and children with fluoride deficiency. The Consumer Health segment is involved in the commercialization of over-the-counter medicines, personal care products, and dietary supplements in various categories, such as hair loss, digestive health, urological health, diabetes management, and allergy. The segment offers Regoxidine - for Men and Women, a proprietary over-the-counter aerosol foam that works to treat hair loss in both men and women; and OmepraCareDR and EsomepraCareDR, acid reducers for the treatment of frequent heartburn. It also engages in the development of AR101 (enzastaurin), an orally available investigational first-in-class small molecule, serine/threonine kinase inhibitor targeting the treatment of vascular Ehlers-Danlos Syndrome. The company was formerly known as Aytu BioScience, Inc. and changed its name to Aytu Biopharma, Inc. in March 2021. Aytu Biopharma, Inc. is based in Denver, Colorado.
Leap Therapeutics logo

Leap Therapeutics

NASDAQ:LPTX
Leap Therapeutics, Inc., a biopharmaceutical company, acquires and develops antibody therapies for the treatment of cancer. Its lead product candidates include DKN-01, a monoclonal antibody that inhibits Dickkopf-related protein 1, which is in multiple ongoing clinical trials for treating esophagogastric and gynecologic cancers; and FL-301, a monoclonal antibody that targets cells that express Claudin18.2 on their cell surface and is in phase II clinical trial, as well as two preclinical antibody programs, FL-302 and FL-501. Leap Therapeutics, Inc. has an option and license agreement with NovaRock, Adimab, and BeiGene, Ltd. to develop and commercialize DKN-01 in Asia (excluding Japan), Australia, and New Zealand. The company was formerly known as HealthCare Pharmaceuticals, Inc. and changed its name to Leap Therapeutics, Inc. in November 2015. Leap Therapeutics, Inc. was incorporated in 2011 and is based in Cambridge, Massachusetts.
Otonomy logo

Otonomy

NASDAQ:OTIC
Otonomy, Inc. operates as a biopharmaceutical company. engages in the development of therapeutics for neurotology. The firm's product pipeline includes OTIVIDEX (dexamethasone) Meniere's disease, OTIPRIO (ciprofloxacin otic suspension) acute otitis media with tubes (AOMT), OTO-313 (gacyclidine) tinnitus, OTO-413 (BDNF) hidden hearing Loss, OTO-510 (otoprotectant) prevent CIHL, OTO-6XX (hair cell regeneration) severe hearing loss. It operates under the Otiprio brand. The company was founded by Jay B. Lichter, Jeffrey Harris, Rick Friedman, and Allen F. Ryan on May 6, 2008 and is headquartered in San Diego, CA.
Synlogic logo

Synlogic

NASDAQ:SYBX
Synlogic, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of synthetic biotics to treat metabolic diseases in the United States. Its pipeline include SYNB1618, an orally administered, non-systemically absorbed drug candidate to treat phenylketonuria; SYNB1934, an orally administered, non-systemically absorbed drug candidate, which is in Phase III clinical trial to treat phenylketonuria; SYNB1353, an orally administered, non-systemically absorbed drug candidate, which is in Phase I clinical to treat homocystinuria; SYNB8802, an orally administered, non-systemically absorbed drug candidate that is in Phase II clinical trial for the treatment of enteric hyperoxaluria; and SYNB2081 to lower uric acid for the potential treatment of gout. The company has a collaboration agreement with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc. for the research and pre-clinical development of a synthetic biotic medicine for the treatment of inflammatory bowel disease; and Ginkgo Bioworks, Inc. Synlogic, Inc. is based in Cambridge, Massachusetts.
Zynerba Pharmaceuticals logo

Zynerba Pharmaceuticals

NASDAQ:ZYNE
Zynerba Pharmaceuticals, Inc. operates as a clinical stage specialty pharmaceutical company. The company focuses on developing pharmaceutically produced transdermal cannabinoid therapies for rare and near-rare neuropsychiatric disorders. It is developing Zygel, a pharmaceutically produced cannabidiol formulated as a permeation-enhanced gel for transdermal delivery. The company was formerly known as AllTranz, Inc. and changed its name to Zynerba Pharmaceuticals, Inc. in August 2014. Zynerba Pharmaceuticals, Inc. was incorporated in 2007 and is headquartered in Devon, Pennsylvania.