S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold
S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold
S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold
S&P 500   4,967.23
DOW   37,986.40
QQQ   414.65
How major US stock indexes fared Friday, 4/19/2024
Stock market today: Tumbling tech stocks drag Wall Street to the finish line of another losing week
American Express profits jump 34%, helped by jump in new customers, higher spending
American Express, Fifth Third rise; Netflix, PPG Industries fall, Friday, 4/19/2024
Intuitive Surgical Stock Can Trend Much Higher This Year 
3 Magnificent Seven Stocks Outperforming the Rest
Bargain Hunting: 3 Stocks With RSIs That Scream Oversold

Compare Stocks

Comparative Price Performance Over Time

Compare Stocks - Price & Volume

CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Allergan plc stock logo
AGN
Allergan
$193.02
$190.89
$114.27
$202.21
$63.50B1.24.01 million shs12.44 million shs
Bayer Aktiengesellschaft stock logo
BAYRY
Bayer Aktiengesellschaft
$7.08
+0.6%
$7.44
$6.96
$16.83
N/A1.131.95 million shs1.99 million shs
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
$896.82
+0.3%
$954.14
$684.80
$998.33
$98.43B0.11495,118 shs507,464 shs
Takeda Pharmaceutical Company Limited stock logo
TAK
Takeda Pharmaceutical
$13.24
+0.6%
$14.20
$13.11
$17.11
$41.90B0.531.85 million shs1.27 million shs
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$394.28
+0.2%
$414.17
$316.43
$448.40
$101.91B0.351.25 million shs1.34 million shs
Beginners Guide To Retirement Stocks Cover

Click the link below and we'll send you MarketBeat's list of seven best retirement stocks and why they should be in your portfolio.

Get This Free Report

Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Allergan plc stock logo
AGN
Allergan
0.00%0.00%0.00%0.00%0.00%
Bayer Aktiengesellschaft stock logo
BAYRY
Bayer Aktiengesellschaft
-0.21%-3.96%+0.70%-20.90%-58.12%
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
-0.80%-2.86%-7.23%-4.22%+10.52%
Takeda Pharmaceutical Company Limited stock logo
TAK
Takeda Pharmaceutical
+0.04%-3.09%-8.67%-10.54%-20.96%
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
+0.10%-1.69%-5.23%-9.55%+19.80%

MarketRank™

CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Allergan plc stock logo
AGN
Allergan
N/AN/AN/AN/AN/AN/AN/AN/A
Bayer Aktiengesellschaft stock logo
BAYRY
Bayer Aktiengesellschaft
N/AN/AN/AN/AN/AN/AN/AN/A
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
3.6165 of 5 stars
2.43.00.02.32.42.51.9
Takeda Pharmaceutical Company Limited stock logo
TAK
Takeda Pharmaceutical
0.2642 of 5 stars
0.02.02.50.01.30.81.9
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
4.2212 of 5 stars
2.24.00.03.32.52.52.5

Analyst Ratings

CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Allergan plc stock logo
AGN
Allergan
N/AN/AN/AN/A
Bayer Aktiengesellschaft stock logo
BAYRY
Bayer Aktiengesellschaft
1.89
ReduceN/AN/A
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
2.70
Moderate Buy$976.418.87% Upside
Takeda Pharmaceutical Company Limited stock logo
TAK
Takeda Pharmaceutical
N/AN/A$14.005.74% Upside
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
2.48
Hold$429.458.92% Upside

Current Analyst Ratings

Latest AGN, REGN, TAK, BAYRY, and VRTX Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
4/18/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Guggenheim
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetBuy ➝ Buy$445.00 ➝ $450.00
4/17/2024
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
UBS Group
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetBuy ➝ Buy$1,090.00 ➝ $1,099.00
4/17/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
UBS Group
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetBuy ➝ Buy$498.00 ➝ $466.00
4/15/2024
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
Cantor Fitzgerald
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingNeutral ➝ Neutral$925.00
4/15/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Oppenheimer
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOutperform ➝ Outperform$500.00
4/12/2024
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
Bank of America
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetUnderperform ➝ Underperform$710.00 ➝ $720.00
4/12/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Canaccord Genuity Group
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingSell ➝ Sell$371.00
4/11/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Evercore ISI
Subscribe to MarketBeat All Access for the recommendation accuracy rating
UpgradeIn-Line ➝ Outperform$438.00
4/11/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetBuy ➝ Buy$457.00 ➝ $462.00
4/9/2024
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
Royal Bank of Canada
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOutperform ➝ Outperform$1,189.00
4/3/2024
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
Truist Financial
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingBuy ➝ Buy$1,135.00
(Data available from 4/19/2021 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Sales & Book Value

CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Allergan plc stock logo
AGN
Allergan
$16.09B3.95$36.70 per share5.26$177.28 per share1.09
Bayer Aktiengesellschaft stock logo
BAYRY
Bayer Aktiengesellschaft
$51.55BN/A$3.85 per share1.84$10.44 per shareN/A
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
$13.12B7.50$43.05 per share20.83$236.63 per share3.79
Takeda Pharmaceutical Company Limited stock logo
TAK
Takeda Pharmaceutical
$29.81B1.41$3.61 per share3.67$14.86 per share0.89
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$9.87B10.33$14.70 per share26.82$68.22 per share5.78

Profitability & Earnings

CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Allergan plc stock logo
AGN
Allergan
-$5.27B$17.64N/A10.651.63-15.44%8.46%5.31%N/A
Bayer Aktiengesellschaft stock logo
BAYRY
Bayer Aktiengesellschaft
-$3.18B-$0.82N/A4.85N/A-6.31%17.27%5.20%N/A
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
$3.95B$34.7525.8122.352.6030.14%17.61%13.76%5/2/2024 (Confirmed)
Takeda Pharmaceutical Company Limited stock logo
TAK
Takeda Pharmaceutical
$2.35B$0.6620.0610.593.726.90%12.57%5.89%5/9/2024 (Estimated)
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$3.62B$13.8928.3924.431.8536.68%21.91%16.73%5/6/2024 (Confirmed)

Latest AGN, REGN, TAK, BAYRY, and VRTX Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
5/6/2024N/A
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$3.61N/A-$3.61N/AN/AN/A  
5/2/2024N/A
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
$8.07N/A-$8.07N/AN/AN/A  
3/5/202412/31/2023
Bayer Aktiengesellschaft stock logo
BAYRY
Bayer Aktiengesellschaft
$0.38$0.50+$0.12$0.63N/A$12.77 billion    
2/5/2024Q4 23
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$3.85$4.20+$0.35$3.43$2.50 billion$2.52 billion    
2/2/202412/31/2023
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
$10.73$11.86+$1.13$10.17$3.29 billion$3.43 billion    
2/1/2024Q3 2024
Takeda Pharmaceutical Company Limited stock logo
TAK
Takeda Pharmaceutical
N/A$0.51+$0.51$0.79N/A$7.52 billion

Dividends

CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Allergan plc stock logo
AGN
Allergan
$2.961.53%N/A16.78%N/A
Bayer Aktiengesellschaft stock logo
BAYRY
Bayer Aktiengesellschaft
$0.456.36%N/AN/A N/A
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
N/AN/AN/AN/AN/A
Takeda Pharmaceutical Company Limited stock logo
TAK
Takeda Pharmaceutical
$0.523.93%N/A78.79%N/A
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
N/AN/AN/AN/AN/A

Latest AGN, REGN, TAK, BAYRY, and VRTX Dividends

AnnouncementCompanyPeriodAmountYieldEx-Dividend DateRecord DatePayable Date
4/3/2024
Bayer Aktiengesellschaft stock logo
BAYRY
Bayer Aktiengesellschaft
$0.01914/29/20244/30/20245/13/2024
(Data available from 1/1/2013 forward)

Debt

CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Allergan plc stock logo
AGN
Allergan
0.31
1.01
0.84
Bayer Aktiengesellschaft stock logo
BAYRY
Bayer Aktiengesellschaft
1.15
1.27
0.80
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
0.10
5.69
4.94
Takeda Pharmaceutical Company Limited stock logo
TAK
Takeda Pharmaceutical
0.64
1.06
0.55
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
0.02
3.99
3.78

Ownership

Miscellaneous

CompanyEmployeesShares OutstandingFree FloatOptionable
Allergan plc stock logo
AGN
Allergan
17,400329.00 millionN/AOptionable
Bayer Aktiengesellschaft stock logo
BAYRY
Bayer Aktiengesellschaft
99,723N/AN/ANot Optionable
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
13,450109.76 million100.07 millionOptionable
Takeda Pharmaceutical Company Limited stock logo
TAK
Takeda Pharmaceutical
49,0953.16 billion3.16 billionOptionable
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
5,400258.46 million257.94 millionOptionable

AGN, REGN, TAK, BAYRY, and VRTX Headlines

SourceHeadline
Vertex Pharmaceuticals (VRTX) Gains As Market Dips: What You Should KnowVertex Pharmaceuticals (VRTX) Gains As Market Dips: What You Should Know
finance.yahoo.com - April 19 at 7:30 PM
RIA Advisory Group LLC Invests $6.89 Million in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)RIA Advisory Group LLC Invests $6.89 Million in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 19 at 5:21 PM
Vertex (VRTX) Begins Rolling NDA Filing for Acute Pain DrugVertex (VRTX) Begins Rolling NDA Filing for Acute Pain Drug
zacks.com - April 19 at 1:01 PM
Vertex Pharmaceuticals Incorporated Forecasted to Post FY2024 Earnings of $15.32 Per Share (NASDAQ:VRTX)Vertex Pharmaceuticals Incorporated Forecasted to Post FY2024 Earnings of $15.32 Per Share (NASDAQ:VRTX)
marketbeat.com - April 19 at 8:50 AM
Is Vertex Pharmaceuticals Stock a Millionaire Maker?Is Vertex Pharmaceuticals Stock a Millionaire Maker?
fool.com - April 19 at 4:30 AM
Vertex Pharmaceuticals (NASDAQ:VRTX) Price Target Cut to $466.00Vertex Pharmaceuticals (NASDAQ:VRTX) Price Target Cut to $466.00
americanbankingnews.com - April 19 at 2:36 AM
NBW Capital LLC Acquires 8,145 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)NBW Capital LLC Acquires 8,145 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 18 at 2:30 PM
Vertex’s stock climbs as non-opioid pain treatment advancesVertex’s stock climbs as non-opioid pain treatment advances
marketwatch.com - April 18 at 9:33 AM
Does This Acquisition Make Vertex Pharmaceuticals Stock a Buy?Does This Acquisition Make Vertex Pharmaceuticals Stock a Buy?
fool.com - April 18 at 8:30 AM
Vertex Pharmaceuticals (NASDAQ:VRTX) Price Target Lowered to $466.00 at UBS GroupVertex Pharmaceuticals (NASDAQ:VRTX) Price Target Lowered to $466.00 at UBS Group
marketbeat.com - April 18 at 8:28 AM
Vertex Pharmaceuticals (NASDAQ:VRTX) Given New $450.00 Price Target at GuggenheimVertex Pharmaceuticals (NASDAQ:VRTX) Given New $450.00 Price Target at Guggenheim
marketbeat.com - April 18 at 8:22 AM
Vertex Announces Advancements of Suzetrigine (VX-548) in Acute and Neuropathic PainVertex Announces Advancements of Suzetrigine (VX-548) in Acute and Neuropathic Pain
businesswire.com - April 18 at 8:00 AM
Brokers Set Expectations for Vertex Pharmaceuticals Incorporateds Q1 2024 Earnings (NASDAQ:VRTX)Brokers Set Expectations for Vertex Pharmaceuticals Incorporated's Q1 2024 Earnings (NASDAQ:VRTX)
americanbankingnews.com - April 18 at 5:48 AM
If You Invested $1000 In This Stock 10 Years Ago, You Would Have $6,000 TodayIf You Invested $1000 In This Stock 10 Years Ago, You Would Have $6,000 Today
benzinga.com - April 17 at 2:21 PM
Everence Capital Management Inc. Has $2.17 Million Stock Holdings in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Everence Capital Management Inc. Has $2.17 Million Stock Holdings in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 17 at 9:25 AM
HealthInvest Partners AB Takes $3.72 Million Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)HealthInvest Partners AB Takes $3.72 Million Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 16 at 6:50 PM
Is Vertex (VRTX) a Buy as Wall Street Analysts Look Optimistic?Is Vertex (VRTX) a Buy as Wall Street Analysts Look Optimistic?
zacks.com - April 16 at 10:31 AM
Vertex Pharmaceuticals (NASDAQ:VRTX) Given Outperform Rating at OppenheimerVertex Pharmaceuticals (NASDAQ:VRTX) Given Outperform Rating at Oppenheimer
americanbankingnews.com - April 16 at 3:38 AM
Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Shares Sold by First American Trust FSBVertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Shares Sold by First American Trust FSB
marketbeat.com - April 15 at 9:41 PM
Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to KnowInvestors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know
zacks.com - April 15 at 10:06 AM
Heres (at Least) 1 new Reason to Buy Vertex Pharmaceuticals StockHere's (at Least) 1 new Reason to Buy Vertex Pharmaceuticals Stock
fool.com - April 15 at 9:15 AM
Vertex Pharmaceuticals (NASDAQ:VRTX) Given "Outperform" Rating at OppenheimerVertex Pharmaceuticals (NASDAQ:VRTX) Given "Outperform" Rating at Oppenheimer
marketbeat.com - April 15 at 8:29 AM
Harel Insurance Investments & Financial Services Ltd. Has $4.12 Million Stock Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Harel Insurance Investments & Financial Services Ltd. Has $4.12 Million Stock Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 14 at 1:39 PM
Vertex Pharmaceuticals (NASDAQ:VRTX) Earns Sell Rating from Canaccord Genuity GroupVertex Pharmaceuticals (NASDAQ:VRTX) Earns Sell Rating from Canaccord Genuity Group
americanbankingnews.com - April 14 at 3:26 AM

New MarketBeat Followers Over Time

Media Sentiment Over Time

Top Headlines

All Headlines

Company Descriptions

Allergan logo

Allergan

NYSE:AGN
Allergan plc, a pharmaceutical company, develops, manufactures, and commercializes branded pharmaceutical, device, biologic, surgical, and regenerative medicine products worldwide. The company operates in three segments: US Specialized Therapeutics, US General Medicine, and International. It offers a portfolio of products in various therapeutic areas, including medical aesthetics and dermatology, eye care, neuroscience, urology, gastrointestinal, women's health, and anti-infective therapeutic products. The company also offers breast implants and tissue expanders; and RM-131 (relamorelin), a peptide ghrelin agonist for the treatment of diabetic gastroparesis. In addition, it develops medical and cosmetic treatments; therapies for non-alcoholic steatohepatitis and other liver diseases; inhibitor for the treatment of psoriasis and other autoimmune disorders; atopic dermatitis drug candidate; peri-ocular rings for extended drug delivery and reducing elevated intraocular pressure in glaucoma patients; and treatments for neurodegenerative disorders, including Alzheimer's disease. Further, the company develops RST-001, a novel gene therapy for the treatment of retinitis pigmentosa; small molecule therapeutics for inflammatory and fibrotic diseases; topical medicines for fat reduction; and delivery system and botulinum toxin-based prescription products. It has collaboration, option, and license agreement with Lyndra, Inc.; and strategic alliance and option agreement with Editas Medicine, Inc. Allergan plc also has licensing agreements with Assembly Biosciences, Inc.; MedImmune; and Heptares Therapeutics, Ltd. The company was formerly known as Actavis plc and changed its name to Allergan plc in June 2015. Allergan plc was founded in 1983 and is headquartered in Dublin, Ireland.
Bayer Aktiengesellschaft logo

Bayer Aktiengesellschaft

OTCMKTS:BAYRY
Bayer Aktiengesellschaft, together its subsidiaries, operates as a life science company worldwide. It operates through Pharmaceuticals, Consumer Health, and Crop Science segments. The Pharmaceuticals segment offers prescription products primarily for cardiology and women's health care; specialty therapeutics in the areas of oncology, hematology, and ophthalmology; and diagnostic imaging equipment and digital solutions, and contrast agents, as well as cell and gene therapy. The Consumer Health segment markets nonprescription over-the-counter medicines for self-medication and self-care; and solutions for nutritional supplements, allergy, cough and cold, dermatology, pain and cardiovascular risk prevention, and digestive health. The Crop Science segment offers seeds, improved plant traits, innovative chemical and biological crop protection products, digital solutions, as well as customer service for agriculture. This segment also provides breeding, propagation, and production/processing of seeds, including seed dressing. The company has a collaboration with Acuitas Therapeutics, Inc. to strengthen gene editing programs; Peking University in the area of basic pharmaceutical research; the Swiss Tropical and Public Health Institute in the development of the compound emodepside for the treatment of infection with soil-transmitted helminths; bit.bio Ltd. for the discovery and manufacture of regulatory T cells for use in creating therapeutics; Hologic, Inc. in the field of contrastenhanced-mammography solutions to improve diagnostic imaging for the detection of breast cancer; and Twist Bioscience Corporation centering around the research and development of antibody-based pharmaceuticals, as well as with CrossBay Medical Inc. It distributes its products through wholesalers, pharmacies and pharmacy chains, supermarkets, online and other retailers, and hospitals, as well as directly to farmers. The company has collaboration with Thermo Fisher Scientific. Bayer Aktiengesellschaft was founded in 1863 and is based in Leverkusen, Germany.
Regeneron Pharmaceuticals logo

Regeneron Pharmaceuticals

NASDAQ:REGN
Regeneron Pharmaceuticals, Inc. discovers, invents, develops, manufactures, and commercializes medicines for treating various diseases worldwide. The company's products include EYLEA injection to treat wet age-related macular degeneration and diabetic macular edema; myopic choroidal neovascularization; diabetic retinopathy; neovascular glaucoma; and retinopathy of prematurity. It also provides Dupixent injection to treat atopic dermatitis and asthma in adults and pediatrics; Libtayo injection to treat metastatic or locally advanced cutaneous squamous cell carcinoma; Praluent injection for heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease in adults; REGEN-COV for covid-19; and Kevzara solution for treating rheumatoid arthritis in adults. In addition, the company offers Inmazeb injection for infection caused by Zaire ebolavirus; ARCALYST injection for cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome and muckle-wells syndrome; and ZALTRAP injection for intravenous infusion to treat metastatic colorectal cancer; and develops product candidates for treating patients with eye, allergic and inflammatory, cardiovascular and metabolic, infectious, and rare diseases; and cancer, pain, and hematologic conditions. The company was incorporated in 1988 and is headquartered in Tarrytown, New York.
Takeda Pharmaceutical logo

Takeda Pharmaceutical

NYSE:TAK
Takeda Pharmaceutical Company Limited engages in the research, development, manufacture, marketing, and out-licensing of pharmaceutical products in Japan and internationally. It offers pharmaceutical products in the areas of gastroenterology, rare diseases, plasma derived therapies, immunology, oncology, and neuroscience. The company provides its products under the Entyvio, Gattex/Revestive, Takecab/Vocinti, Alofisel, Dexilant, Pantoloc/Controloc, Adynovate/Adynovi, Feiba, Recombinate, Hemofil/Immunate/Immunine, Takhzyro, Livtencity, Elaprase, Replagal, Advate, Flexbumin, Vpriv, Gammagard Liquid/Kiovig, Hyqvia, Cuvitru, Exkivity, Ninlaro, Velcade, Azilva-F, Lotriga, Iclusig, Leuplin/Enantone, Adcetris, vyvanse/elvanse, Trintellix, and Alunbrig brands. It has in-license agreement with BioMarin, Luxna Biotech, GlaxoSmithKline, Halozyme, and Kamada; collaboration with Neurocrine Biosciences, Inc., Seagen Inc., Anima Biotech, Denali Therapeutics, KSQ Therapeutics, Noile-Immune Biotech, Center for iPS Cell Research Application, Kyoto University (CiRA), and Charles River Laboratories; licensing agreement with Mirum Pharmaceuticals and Twist Bioscience, UCSD/Fortis Advisors, PeptiDream, MD Anderson Cancer Center, Teva Pharmaceutical Industries, and Xenetic Biosciences; collaboration and licensing agreement with Arrowhead Pharmaceuticals Inc., Engitix, Genevant Sciences Corporation, Sosei Heptares, Zedira/Dr. Falk Pharma, Exelixis, Inc., GlaxoSmithKline, Heidelberg Pharma, HUTCHMED, Presage Biosciences, Codexis, Inc., Ensoma, Envozyne, KM Biologics, and Selecta BioScience, and Ovid Therapeutics Inc.; and collaboration with ZEDIRA GmbH and Dr. Falk Pharma GmbH. It has research collaboration and licensing agreement with Crescendo Biologics, Code Bio, Immusoft, Poseida Therapeutics, and Selecta Biosciences. The company was founded in 1781 and is headquartered in Tokyo, Japan.
Vertex Pharmaceuticals logo

Vertex Pharmaceuticals

NASDAQ:VRTX
Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age or older; SYMDEKO/SYMKEVI for people with CF for 6 years of age or older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 year or older who have CF with ivacaftor. The company's pipeline includes VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1 clinical trial; VX-548, a non-opioid medicine for the treatment of acute and neuropathic pain which is in Phase 3 clinical trial; Exa-cel, for the treatment of sickle cell disease and transfusion-dependent beta thalassemia which is in Phase 2/3 clinical trial. In addition, it provides inaxaplin for the treatment of APOL1-mediated focal segmental glomerulosclerosis and co-morbidities, such as hypertension which is in single Phase 2/3; VX- 880 and VX-264, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-970, which is in Phase 2 clinical trial for the treatment of cancer; and VX-803 and VX-984 for treatment of cancer in Phase 1 clinical trial. Further, it sells the products to specialty pharmacy and specialty distributors in the United States, as well as retail pharmacies, hospitals, and clinics. Additionally, the company has collaborations with CRISPR Therapeutics AG.; Moderna, Inc.; Entrada Therapeutics, Inc.; Arbor Biotechnologies, Inc.; Mammoth Biosciences, Inc.; and Verve Therapeutics., as well as collaborations with Tevard Biosciences to develop novel tRNA-based therapies for duchenne muscular dystrophy. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.