S&P 500   5,011.12
DOW   37,775.38
QQQ   423.41
Stock market today: Wall Street drifts to a mixed finish as yields tick higher
What's Driving Tesla Lower Ahead of its Earnings?
How major US stock indexes fared Thursday, 4/18/2024
3 Steel Stocks Could Soar on New China Tariffs
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CSX Co.: The Railroad Powering Ahead with an Earnings Beat
'There is no time to waste': EU leaders want to boost competitiveness to close gap with US and China
S&P 500   5,011.12
DOW   37,775.38
QQQ   423.41
Stock market today: Wall Street drifts to a mixed finish as yields tick higher
What's Driving Tesla Lower Ahead of its Earnings?
How major US stock indexes fared Thursday, 4/18/2024
3 Steel Stocks Could Soar on New China Tariffs
These are the Top 4 Stocks for Buybacks in 2024
CSX Co.: The Railroad Powering Ahead with an Earnings Beat
'There is no time to waste': EU leaders want to boost competitiveness to close gap with US and China
S&P 500   5,011.12
DOW   37,775.38
QQQ   423.41
Stock market today: Wall Street drifts to a mixed finish as yields tick higher
What's Driving Tesla Lower Ahead of its Earnings?
How major US stock indexes fared Thursday, 4/18/2024
3 Steel Stocks Could Soar on New China Tariffs
These are the Top 4 Stocks for Buybacks in 2024
CSX Co.: The Railroad Powering Ahead with an Earnings Beat
'There is no time to waste': EU leaders want to boost competitiveness to close gap with US and China
S&P 500   5,011.12
DOW   37,775.38
QQQ   423.41
Stock market today: Wall Street drifts to a mixed finish as yields tick higher
What's Driving Tesla Lower Ahead of its Earnings?
How major US stock indexes fared Thursday, 4/18/2024
3 Steel Stocks Could Soar on New China Tariffs
These are the Top 4 Stocks for Buybacks in 2024
CSX Co.: The Railroad Powering Ahead with an Earnings Beat
'There is no time to waste': EU leaders want to boost competitiveness to close gap with US and China

Compare Stocks

Comparative Price Performance Over Time

Compare Stocks - Price & Volume

CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Becton, Dickinson and Company stock logo
BDX
Becton, Dickinson and Company
$233.15
+0.4%
$240.34
$229.40
$287.32
$67.36B0.431.41 million shs891,562 shs
EssilorLuxottica Société anonyme stock logo
ESLOY
EssilorLuxottica Société anonyme
$108.85
+1.7%
$108.76
$84.17
$115.51
$98.80B1.1834,227 shs22,441 shs
H. Lundbeck A/S stock logo
HLUYY
H. Lundbeck A/S
$22.00
0.0%
$22.00
$10.00
$31.55
$21.91B0.681,758 shs7,500 shs
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$393.48
+0.1%
$414.76
$316.43
$448.40
$101.70B0.351.25 million shs948,866 shs
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Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Becton, Dickinson and Company stock logo
BDX
Becton, Dickinson and Company
+0.54%-3.69%-2.29%-1.17%-8.41%
EssilorLuxottica Société anonyme stock logo
ESLOY
EssilorLuxottica Société anonyme
-0.99%-1.01%-4.80%+10.31%+14.04%
H. Lundbeck A/S stock logo
HLUYY
H. Lundbeck A/S
0.00%0.00%0.00%0.00%0.00%
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
-0.27%-1.13%-4.44%-9.21%+20.90%

MarketRank™

CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Becton, Dickinson and Company stock logo
BDX
Becton, Dickinson and Company
4.7621 of 5 stars
2.43.03.34.03.42.52.5
EssilorLuxottica Société anonyme stock logo
ESLOY
EssilorLuxottica Société anonyme
0.3304 of 5 stars
0.03.01.70.00.60.01.3
H. Lundbeck A/S stock logo
HLUYY
H. Lundbeck A/S
N/AN/AN/AN/AN/AN/AN/AN/A
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
4.3149 of 5 stars
2.24.00.03.33.22.52.5

Analyst Ratings

CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Becton, Dickinson and Company stock logo
BDX
Becton, Dickinson and Company
2.80
Moderate Buy$280.0020.09% Upside
EssilorLuxottica Société anonyme stock logo
ESLOY
EssilorLuxottica Société anonyme
2.00
HoldN/AN/A
H. Lundbeck A/S stock logo
HLUYY
H. Lundbeck A/S
1.50
ReduceN/AN/A
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
2.43
Hold$429.459.14% Upside

Current Analyst Ratings

Latest ESLOY, HLUYY, BDX, and VRTX Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
4/18/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Guggenheim
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetBuy ➝ Buy$445.00 ➝ $450.00
4/17/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
UBS Group
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetBuy ➝ Buy$498.00 ➝ $466.00
4/15/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Oppenheimer
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOutperform ➝ Outperform$500.00
4/12/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Canaccord Genuity Group
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingSell ➝ Sell$371.00
4/11/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Evercore ISI
Subscribe to MarketBeat All Access for the recommendation accuracy rating
UpgradeIn-Line ➝ Outperform$438.00
4/11/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetBuy ➝ Buy$457.00 ➝ $462.00
2/20/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Cantor Fitzgerald
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOverweight ➝ Overweight$440.00
2/15/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Wolfe Research
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOutperform$515.00
2/6/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Cantor Fitzgerald
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOverweight ➝ Overweight$440.00
2/6/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Royal Bank of Canada
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetSector Perform ➝ Sector Perform$397.00 ➝ $420.00
2/5/2024
Becton, Dickinson and Company stock logo
BDX
Becton, Dickinson and Company
Barclays
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetOverweight ➝ Overweight$301.00 ➝ $305.00
(Data available from 4/18/2021 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Sales & Book Value

CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Becton, Dickinson and Company stock logo
BDX
Becton, Dickinson and Company
$19.37B3.48$20.40 per share11.43$88.92 per share2.62
EssilorLuxottica Société anonyme stock logo
ESLOY
EssilorLuxottica Société anonyme
$27.48B3.60$7.10 per share15.33$46.37 per share2.35
H. Lundbeck A/S stock logo
HLUYY
H. Lundbeck A/S
$2.59B8.45$3.36 per share6.54$14.60 per share1.51
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$9.87B10.30$14.63 per share26.90$68.22 per share5.77

Profitability & Earnings

CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Becton, Dickinson and Company stock logo
BDX
Becton, Dickinson and Company
$1.48B$4.2255.2516.281.916.44%13.57%6.56%5/2/2024 (Confirmed)
EssilorLuxottica Société anonyme stock logo
ESLOY
EssilorLuxottica Société anonyme
$2.48BN/A0.0026.042.96N/AN/AN/AN/A
H. Lundbeck A/S stock logo
HLUYY
H. Lundbeck A/S
$209.69M$0.8825.007.72N/A6.74%13.74%7.16%N/A
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$3.62B$13.8928.3323.911.8436.68%21.91%16.73%5/6/2024 (Confirmed)

Latest ESLOY, HLUYY, BDX, and VRTX Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
5/6/2024N/A
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$3.61N/A-$3.61N/AN/AN/A  
5/2/2024N/A
Becton, Dickinson and Company stock logo
BDX
Becton, Dickinson and Company
$2.96N/A-$2.96N/AN/AN/A  
2/5/2024Q4 23
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$3.85$4.20+$0.35$3.43$2.50 billion$2.52 billion    
2/1/2024Q1 2024
Becton, Dickinson and Company stock logo
BDX
Becton, Dickinson and Company
$2.39$2.68+$0.29$4.40$4.73 billion$4.71 billion      

Dividends

CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Becton, Dickinson and Company stock logo
BDX
Becton, Dickinson and Company
$3.801.63%+4.77%90.05%52 Years
EssilorLuxottica Société anonyme stock logo
ESLOY
EssilorLuxottica Société anonyme
$1.421.30%N/AN/AN/A
H. Lundbeck A/S stock logo
HLUYY
H. Lundbeck A/S
$0.200.91%N/A22.73%N/A
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
N/AN/AN/AN/AN/A

Latest ESLOY, HLUYY, BDX, and VRTX Dividends

AnnouncementCompanyPeriodAmountYieldEx-Dividend DateRecord DatePayable Date
1/23/2024
Becton, Dickinson and Company stock logo
BDX
Becton, Dickinson and Company
quarterly$0.951.59%3/7/20243/8/20243/29/2024
(Data available from 1/1/2013 forward)

Debt

CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Becton, Dickinson and Company stock logo
BDX
Becton, Dickinson and Company
0.56
1.08
0.64
EssilorLuxottica Société anonyme stock logo
ESLOY
EssilorLuxottica Société anonyme
0.17
1.00
0.72
H. Lundbeck A/S stock logo
HLUYY
H. Lundbeck A/S
0.32
1.15
0.71
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
0.02
3.99
3.78

Ownership

Miscellaneous

CompanyEmployeesShares OutstandingFree FloatOptionable
Becton, Dickinson and Company stock logo
BDX
Becton, Dickinson and Company
73,000288.90 million288.01 millionOptionable
EssilorLuxottica Société anonyme stock logo
ESLOY
EssilorLuxottica Société anonyme
190,000907.69 millionN/ANot Optionable
H. Lundbeck A/S stock logo
HLUYY
H. Lundbeck A/S
5,348995.74 millionN/ANot Optionable
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
5,400258.46 million257.94 millionOptionable

ESLOY, HLUYY, BDX, and VRTX Headlines

SourceHeadline
NBW Capital LLC Acquires 8,145 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)NBW Capital LLC Acquires 8,145 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 18 at 2:30 PM
Vertex’s stock climbs as non-opioid pain treatment advancesVertex’s stock climbs as non-opioid pain treatment advances
marketwatch.com - April 18 at 9:33 AM
Does This Acquisition Make Vertex Pharmaceuticals Stock a Buy?Does This Acquisition Make Vertex Pharmaceuticals Stock a Buy?
fool.com - April 18 at 8:30 AM
Vertex Pharmaceuticals (NASDAQ:VRTX) Price Target Lowered to $466.00 at UBS GroupVertex Pharmaceuticals (NASDAQ:VRTX) Price Target Lowered to $466.00 at UBS Group
marketbeat.com - April 18 at 8:28 AM
Vertex Pharmaceuticals (NASDAQ:VRTX) Given New $450.00 Price Target at GuggenheimVertex Pharmaceuticals (NASDAQ:VRTX) Given New $450.00 Price Target at Guggenheim
marketbeat.com - April 18 at 8:22 AM
Vertex Announces Advancements of Suzetrigine (VX-548) in Acute and Neuropathic PainVertex Announces Advancements of Suzetrigine (VX-548) in Acute and Neuropathic Pain
businesswire.com - April 18 at 8:00 AM
Brokers Set Expectations for Vertex Pharmaceuticals Incorporateds Q1 2024 Earnings (NASDAQ:VRTX)Brokers Set Expectations for Vertex Pharmaceuticals Incorporated's Q1 2024 Earnings (NASDAQ:VRTX)
americanbankingnews.com - April 18 at 5:48 AM
If You Invested $1000 In This Stock 10 Years Ago, You Would Have $6,000 TodayIf You Invested $1000 In This Stock 10 Years Ago, You Would Have $6,000 Today
benzinga.com - April 17 at 2:21 PM
Everence Capital Management Inc. Has $2.17 Million Stock Holdings in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Everence Capital Management Inc. Has $2.17 Million Stock Holdings in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 17 at 9:25 AM
HealthInvest Partners AB Takes $3.72 Million Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)HealthInvest Partners AB Takes $3.72 Million Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 16 at 6:50 PM
Is Vertex (VRTX) a Buy as Wall Street Analysts Look Optimistic?Is Vertex (VRTX) a Buy as Wall Street Analysts Look Optimistic?
zacks.com - April 16 at 10:31 AM
Vertex Pharmaceuticals (NASDAQ:VRTX) Given Outperform Rating at OppenheimerVertex Pharmaceuticals (NASDAQ:VRTX) Given Outperform Rating at Oppenheimer
americanbankingnews.com - April 16 at 3:38 AM
Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Shares Sold by First American Trust FSBVertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Shares Sold by First American Trust FSB
marketbeat.com - April 15 at 9:41 PM
Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to KnowInvestors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know
zacks.com - April 15 at 10:06 AM
Heres (at Least) 1 new Reason to Buy Vertex Pharmaceuticals StockHere's (at Least) 1 new Reason to Buy Vertex Pharmaceuticals Stock
fool.com - April 15 at 9:15 AM
Vertex Pharmaceuticals (NASDAQ:VRTX) Given "Outperform" Rating at OppenheimerVertex Pharmaceuticals (NASDAQ:VRTX) Given "Outperform" Rating at Oppenheimer
marketbeat.com - April 15 at 8:29 AM
Harel Insurance Investments & Financial Services Ltd. Has $4.12 Million Stock Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Harel Insurance Investments & Financial Services Ltd. Has $4.12 Million Stock Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 14 at 1:39 PM
Vertex Pharmaceuticals (NASDAQ:VRTX) Earns Sell Rating from Canaccord Genuity GroupVertex Pharmaceuticals (NASDAQ:VRTX) Earns Sell Rating from Canaccord Genuity Group
americanbankingnews.com - April 14 at 3:26 AM
Vertex Pharmaceuticals (NASDAQ:VRTX) Raised to Strong-Buy at StockNews.comVertex Pharmaceuticals (NASDAQ:VRTX) Raised to Strong-Buy at StockNews.com
americanbankingnews.com - April 14 at 1:44 AM
Mn Services Vermogensbeheer B.V. Sells 4,400 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Mn Services Vermogensbeheer B.V. Sells 4,400 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 13 at 7:30 PM
Could This Stock Be the Next Biotech Buyout?Could This Stock Be the Next Biotech Buyout?
fool.com - April 13 at 5:29 AM
Vertex Pharmaceuticals (NASDAQ:VRTX) PT Raised to $462.00Vertex Pharmaceuticals (NASDAQ:VRTX) PT Raised to $462.00
americanbankingnews.com - April 13 at 2:54 AM
Vertex Pharmaceuticals (NASDAQ:VRTX) Rating Increased to Outperform at Evercore ISIVertex Pharmaceuticals (NASDAQ:VRTX) Rating Increased to Outperform at Evercore ISI
americanbankingnews.com - April 13 at 2:54 AM
Vertex Pharmaceuticals (NASDAQ:VRTX) Rating Increased to Strong-Buy at StockNews.comVertex Pharmaceuticals (NASDAQ:VRTX) Rating Increased to Strong-Buy at StockNews.com
marketbeat.com - April 12 at 11:17 PM

New MarketBeat Followers Over Time

Media Sentiment Over Time

Company Descriptions

Becton, Dickinson and Company logo

Becton, Dickinson and Company

NYSE:BDX
Becton, Dickinson and Company develops, manufactures, and sells medical supplies, devices, laboratory equipment, and diagnostic products for healthcare institutions, physicians, life science researchers, clinical laboratories, pharmaceutical industry, and the general public worldwide. The company operates in three segments: BD Medical, BD Life Sciences, and BD Interventional. The BD Medical segment provides peripheral intravenous (IV) and advanced peripheral catheters, central lines, acute dialysis catheters, vascular access technology, vascular care and preparation products, needle-free IV connectors and extensions sets, closed-system drug transfer devices, hazardous drug detections, hypodermic syringes and needles, anesthesia needles and trays, enteral syringes, and sharps disposal systems; IV medication safety and infusion therapy delivery systems, medication compounding workflow systems, automated medication dispensing and supply management systems, and medication inventory optimization and tracking systems; and prefillable drug delivery systems. The BD Life Sciences segment offers specimen and blood collection products; automated blood and tuberculosis culturing, molecular testing, microorganism identification and drug susceptibility, and liquid-based cytology systems, as well as rapid diagnostic assays, microbiology laboratory automation products, and plated media products; and fluorescence-activated cell sorters and analyzers, antibodies and kits, reagent systems, and solutions for single-cell gene expression analysis, as well as clinical oncology, immunological, and transplantation diagnostic/monitoring reagents and analyzers. The BD Interventional segment provides hernia and soft tissue repair, biological and bioresorbable grafts, biosurgery, and other surgical products; surgical infection prevention; peripheral intervention products; and urology and critical care products. The company was founded in 1897 and is headquartered in Franklin Lakes, New Jersey.
EssilorLuxottica Société anonyme logo

EssilorLuxottica Société anonyme

OTCMKTS:ESLOY
EssilorLuxottica Société anonyme designs, manufactures, and distributes ophthalmic lenses, frames, and sunglasses in Europe, the Middle East, Africa, Latin America, the Asia-Pacific, and North America. It operates through Professional Solutions and Direct to Consumer segments. The company offers lens under the Essilor, Varilux, Crizal, Eyezen, Stellest, Xperio, Transitions, Ray-Ban, Oakley, Barberini, KODAK Lens, Nikon, Shamir, eyexpert, iWear, Humanware, and Optifog brands. It also provides finishing equipment, vision performance screening, eye examination and refractions, fitting parameter measurements, and small tools and consumables under the Essilor Instruments brand; high-tech equipment for optical surfacing, polishing, measuring, coating, and finishing, as well as consumables, tools, and services under the Satisloh brand. In addition, the company provides eyewear products under the Ray-Ban, Oakley, Persol, Oliver Peoples, Vogue Eyewear, Arnette, Alain Mikli, Costa, Bliz, Native, Luxottica, Sferoflex, Bolon, Molsion, DbyD, and Unofficial and Seen, as well as other Licensed brands. In addition, the company designs, develops, markets, and maintains lens edging and mounting instruments for opticians and prescription laboratories; and optometry instruments for eyecare professionals, schools, occupational medicine centers, military, and other institutions. It wholesales its products to independent opticians, distributors, third-party e-commerce platforms, and large retail chains in the eyecare and eyewear industry; and sells directly to consumers through the network of brick and mortar retail network and its online channels. The company was formerly known as Essilor International Société Anonyme and changed its name to EssilorLuxottica Société anonyme in October 2018. EssilorLuxottica Société anonyme was founded in 1849 and is headquartered in Paris, France.
H. Lundbeck A/S logo

H. Lundbeck A/S

OTCMKTS:HLUYY
H. Lundbeck A/S, a biopharmaceutical company, engages in the research, development, production, and sale of pharmaceuticals for the treatment of psychiatric and neurological disorders in Europe, North America, and internationally. The company's principal products include Abilify Maintena for schizophrenia; Brintellix/Trintellix to treat depression; Northera for the treatment of symptomatic neurogenic orthostatic hypotension; Vyepti for migraine prevention; and Rexulti/Rxulti to treat depression/schizophrenia. It also provides Azilect for treating Parkinson's disease; Cipralex/Lexapro for depression; Ebixa to treat Alzheimer's disease; Onfi for Lennox-Gastaut syndrome; Sabril for treating epilepsy; and Xenazine for chorea associated with Huntington's disease, as well as other products. The company sells its products primarily to distributors of pharmaceuticals, pharmacies, and hospitals. It has a partnership agreement with Verantos to focus on a study to enable real-world evidence in support of migraine therapy; and collaboration with Rgenta Therapeutics, Inc. The company was founded in 1915 and is headquartered in Valby, Denmark.
Vertex Pharmaceuticals logo

Vertex Pharmaceuticals

NASDAQ:VRTX
Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age or older; SYMDEKO/SYMKEVI for people with CF for 6 years of age or older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 year or older who have CF with ivacaftor. The company's pipeline includes VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1 clinical trial; VX-548, a non-opioid medicine for the treatment of acute and neuropathic pain which is in Phase 3 clinical trial; Exa-cel, for the treatment of sickle cell disease and transfusion-dependent beta thalassemia which is in Phase 2/3 clinical trial. In addition, it provides inaxaplin for the treatment of APOL1-mediated focal segmental glomerulosclerosis and co-morbidities, such as hypertension which is in single Phase 2/3; VX- 880 and VX-264, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-970, which is in Phase 2 clinical trial for the treatment of cancer; and VX-803 and VX-984 for treatment of cancer in Phase 1 clinical trial. Further, it sells the products to specialty pharmacy and specialty distributors in the United States, as well as retail pharmacies, hospitals, and clinics. Additionally, the company has collaborations with CRISPR Therapeutics AG.; Moderna, Inc.; Entrada Therapeutics, Inc.; Arbor Biotechnologies, Inc.; Mammoth Biosciences, Inc.; and Verve Therapeutics., as well as collaborations with Tevard Biosciences to develop novel tRNA-based therapies for duchenne muscular dystrophy. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.