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5Am Venture Management, LLC Top Holdings and 13F Report (2024)

About 5Am Venture Management, LLC

Investment Activity

  • 5Am Venture Management, LLC has $446.63 million in total holdings as of March 31, 2024.
  • 5Am Venture Management, LLC owns shares of 26 different stocks, but just 14 companies or ETFs make up 80% of its holdings.
  • Approximately 15.45% of the portfolio was purchased this quarter.
  • About 22.86% of the portfolio was sold this quarter.
  • This quarter, 5Am Venture Management, LLC has purchased 25 new stocks and bought additional shares in 4 stocks.
  • 5Am Venture Management, LLC sold shares of 5 stocks and completely divested from 4 stocks this quarter.

Largest Holdings

DIANTHUS THERAPEUTICS INC
$37,260,870
Merus
$24,713,590

Largest New Holdings this Quarter

PRAXIS PRECISION MEDICINES I
$20,746,800 Holding
Centessa Pharmaceuticals
$14,068,500 Holding
Silence Therapeutics
$10,285,920 Holding
ADVERUM BIOTECHNOLOGIES INC
$7,659,157 Holding
Q32 BIO INC
$4,293,978 Holding

Largest Purchases this Quarter

PRAXIS PRECISION MEDICINES I
340,000 shares (about $20.75M)
Centessa Pharmaceuticals
1,245,000 shares (about $14.07M)
Silence Therapeutics
476,200 shares (about $10.29M)
ADVERUM BIOTECHNOLOGIES INC
541,666 shares (about $7.66M)
Tyra Biosciences
384,319 shares (about $6.30M)

Largest Sales this Quarter

Viking Therapeutics
347,440 shares (about $28.49M)
Enliven Therapeutics
1,325,000 shares (about $23.31M)
DIANTHUS THERAPEUTICS INC
230,235 shares (about $6.91M)
Biohaven
80,000 shares (about $4.38M)
MoonLake Immunotherapeutics
20,317 shares (about $1.02M)

Sector Allocation Over Time

Map of 500 Largest Holdings of5Am Venture Management, LLC

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
Enliven Therapeutics, Inc. stock logo
ELVN
Enliven Therapeutics
$67,474,800$23,306,750 -25.7%3,835,97515.1%Medical
Entrada Therapeutics, Inc. stock logo
TRDA
Entrada Therapeutics
$62,466,7300.0%4,408,37914.0%Medical
DIANTHUS THERAPEUTICS INC
$37,260,870$6,907,050 -15.6%1,242,0298.3%COM
Merus stock logo
MRUS
Merus
$24,713,590$1,229,049 5.2%548,8255.5%Medical
Celldex Therapeutics, Inc. stock logo
CLDX
Celldex Therapeutics
$20,870,4220.0%497,2704.7%Medical
PRAXIS PRECISION MEDICINES I
$20,746,800$20,746,800 New Holding340,0004.6%COM NEW
Viking Therapeutics, Inc. stock logo
VKTX
Viking Therapeutics
$19,479,920$28,490,080 -59.4%237,5604.4%Medical
Pharvaris stock logo
PHVS
Pharvaris
$18,432,5360.0%797,6004.1%Medical
Biohaven Ltd. stock logo
BHVN
Biohaven
$17,499,269$4,375,200 -20.0%319,9723.9%Medical
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
$16,984,9640.0%665,5553.8%Medical
Tyra Biosciences, Inc. stock logo
TYRA
Tyra Biosciences
$15,404,487$6,302,832 69.2%939,2983.4%Medical
Vor Biopharma Inc. stock logo
VOR
Vor Biopharma
$15,077,2840.0%6,361,7233.4%Medical
MoonLake Immunotherapeutics stock logo
MLTX
MoonLake Immunotherapeutics
$14,180,582$1,020,523 -6.7%282,3133.2%Medical
Centessa Pharmaceuticals plc stock logo
CNTA
Centessa Pharmaceuticals
$14,068,500$14,068,500 New Holding1,245,0003.1%Medical
Viridian Therapeutics, Inc. stock logo
VRDN
Viridian Therapeutics
$12,897,778$2,626,500 25.6%736,5952.9%Medical
Silence Therapeutics plc stock logo
SLN
Silence Therapeutics
$10,285,920$10,285,920 New Holding476,2002.3%Medical
AnaptysBio, Inc. stock logo
ANAB
AnaptysBio
$8,056,1470.0%357,7331.8%Medical
Zentalis Pharmaceuticals, Inc. stock logo
ZNTL
Zentalis Pharmaceuticals
$7,722,4000.0%490,0001.7%Medical
ADVERUM BIOTECHNOLOGIES INC
$7,659,157$7,659,157 New Holding541,6661.7%COM NEW
Rallybio Co. stock logo
RLYB
Rallybio
$6,716,8390.0%3,630,7241.5%Medical
GH Research PLC stock logo
GHRS
GH Research
$6,104,609$1,793,662 41.6%572,6651.4%Medical
scPharmaceuticals Inc. stock logo
SCPH
scPharmaceuticals
$6,027,2480.0%1,200,6471.3%Medical
Mersana Therapeutics, Inc. stock logo
MRSN
Mersana Therapeutics
$5,846,4000.0%1,305,0001.3%Medical
Cogent Biosciences, Inc. stock logo
COGT
Cogent Biosciences
$5,311,7570.0%790,4401.2%Medical
Q32 BIO INC
$4,293,978$4,293,978 New Holding251,9941.0%COM
Cidara Therapeutics, Inc. stock logo
CDTX
Cidara Therapeutics
$1,043,7500.0%1,134,5110.2%Medical
Disc Medicine, Inc. stock logo
IRON
Disc Medicine
$0$16,994,205 -100.0%00.0%Medical
Mirati Therapeutics, Inc. stock logo
MRTX
Mirati Therapeutics
$0$11,309,375 -100.0%00.0%Medical
Spruce Biosciences, Inc. stock logo
SPRB
Spruce Biosciences
$0$6,926,520 -100.0%00.0%Medical
Homology Medicines, Inc. stock logo
FIXX
Homology Medicines
$0$2,757,839 -100.0%00.0%Medical

Showing largest 100 holdings. View all holdings.

More Institutional Buying and Selling Information

SEC Filings and Trading Data: