Ecor1 Capital, LLC Top Holdings and 13F Report (2021)

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About Ecor1 Capital, LLC

Investment Activity

Ecor1 Capital, LLC has $3.95 billion in total holdings as of September 30, 2021.
Ecor1 Capital, LLC owns shares of 57 different stocks, but just 18 companies or ETFs make up 80% of its holdings.
Approximately 17.55% of the portfolio was purchased this quarter.
About 16.38% of the portfolio was sold this quarter.
This quarter, Ecor1 Capital, LLC has purchased 51 new stocks and bought additional shares in 9 stocks.
Ecor1 Capital, LLC sold shares of 3 stocks and completely divested from 10 stocks this quarter.

Largest Holdings

Apellis Pharmaceuticals: $667,589,442
Prothena: $286,942,616
Arvinas: $277,669,548
Sarepta Therapeutics: $248,541,839
Crinetics Pharmaceuticals: $194,513,104

Largest New Holdings this Quarter

CRISPR Therapeutics: $94,693,052 Holding
Adaptimmune Therapeutics: $43,298,431 Holding
Celldex Therapeutics: $27,280,500 Holding
LENZ THERAPEUTICS INC: $27,237,553 Holding
Nkarta: $21,620,000 Holding

Largest Purchases this Quarter

Sarepta Therapeutics: 1,086,928 shares (about $140.71M)
Crinetics Pharmaceuticals: 2,142,858 shares (about $100.31M)
CRISPR Therapeutics: 1,389,276 shares (about $94.69M)
Morphic: 2,173,122 shares (about $76.49M)
Adaptimmune Therapeutics: 27,404,070 shares (about $43.30M)

Largest Sales this Quarter

Edgewise Therapeutics: 2,242,809 shares (about $40.91M)
Atea Pharmaceuticals: 850,000 shares (about $3.43M)
ProQR Therapeutics: 95,659 shares (about $219.05K)

Sector Allocation Over Time

Selling

Neutral

Buying

Latest 13F Holdings and Changes Since Previous Quarterly Filing

Issuer Name	Holdings Value	Approximate Purchase/Sale	Change in Shares	Shares Held	% of Portfolio	Sector
APLS Apellis Pharmaceuticals	$667,589,442	$10,836,504 ▲	1.7%	11,357,425	16.9%	Medical
PRTA Prothena	$286,942,616		0.0%	11,584,280	7.3%	Medical
ARVN Arvinas	$277,669,548		0.0%	6,726,491	7.0%	Medical
SRPT Sarepta Therapeutics	$248,541,839	$140,713,699 ▲	130.5%	1,919,835	6.3%	Medical
CRNX Crinetics Pharmaceuticals	$194,513,104	$100,307,183 ▲	106.5%	4,155,375	4.9%	Medical
GLPG Galapagos	$185,351,830		0.0%	5,756,268	4.7%	Medical
ANAB AnaptysBio	$169,373,460		0.0%	7,521,024	4.3%	Medical
ZYME Zymeworks	$141,362,216		0.0%	13,437,473	3.6%	Medical
KURA Kura Oncology	$138,791,558	$14,931,000 ▲	12.1%	6,506,871	3.5%	Medical
JAZZ Jazz Pharmaceuticals	$122,100,100		0.0%	1,013,952	3.1%	Medical
XNCR Xencor	$117,962,106	$1,060,027 ▲	0.9%	5,330,416	3.0%	Medical
ACAD ACADIA Pharmaceuticals	$110,782,447		0.0%	5,991,479	2.8%	Medical
TNGX Tango Therapeutics	$105,846,044		0.0%	13,330,736	2.7%	Medical
IMNM Immunome	$95,743,962		0.0%	3,879,415	2.4%	Medical
CRSP CRISPR Therapeutics	$94,693,052	$94,693,052 ▲	New Holding	1,389,276	2.4%	Medical
MRSN Mersana Therapeutics	$86,753,802		0.0%	19,364,688	2.2%	Medical
MORF Morphic	$83,930,317	$76,493,895 ▲	1,028.6%	2,384,384	2.1%	Medical
NUVB Nuvation Bio	$69,923,101		0.0%	19,209,643	1.8%	Medical
NEUROGENE INC	$64,711,308		0.0%	1,271,342	1.6%	COM
CNTA Centessa Pharmaceuticals	$63,492,203		0.0%	5,618,779	1.6%	Medical
ORIC ORIC Pharmaceuticals	$46,998,435		0.0%	3,418,068	1.2%	Medical
ADAP Adaptimmune Therapeutics	$43,298,431	$43,298,431 ▲	New Holding	27,404,070	1.1%	Medical
TCRX TScan Therapeutics	$39,700,000		0.0%	5,000,000	1.0%	Medical
VYGR Voyager Therapeutics	$36,472,353	$614,823 ▲	1.7%	3,917,546	0.9%	Medical
THRD TF Financial	$30,042,271		0.0%	3,182,444	0.8%	Medical
NEUMORA THERAPEUTICS INC.	$28,482,438		0.0%	2,071,450	0.7%	COM
CLDX Celldex Therapeutics	$27,280,500	$27,280,500 ▲	New Holding	650,000	0.7%	Medical
ITOS iTeos Therapeutics	$27,269,756	$12,060,856 ▲	79.3%	1,999,249	0.7%	Medical
LENZ THERAPEUTICS INC	$27,237,553	$27,237,553 ▲	New Holding	1,219,774	0.7%	COM ADDED
AVIR Atea Pharmaceuticals	$24,829,278	$3,434,000 ▼	-12.2%	6,145,861	0.6%	Medical
ALEC Alector	$24,420,419		0.0%	4,056,548	0.6%	Medical
EWTX Edgewise Therapeutics	$22,807,022	$40,908,835 ▼	-64.2%	1,250,385	0.6%	Medical
NKTX Nkarta	$21,620,000	$21,620,000 ▲	New Holding	2,000,000	0.5%	Medical
PHVS Pharvaris	$20,799,000		0.0%	900,000	0.5%	Medical
PCVX Vaxcyte	$20,493,000	$20,493,000 ▲	New Holding	300,000	0.5%	Medical
MDGL Madrigal Pharmaceuticals	$20,028,000	$20,028,000 ▲	New Holding	75,000	0.5%	Medical
RNA Avidity Biosciences	$19,333,340	$19,333,340 ▲	New Holding	757,576	0.5%	Medical
OVID Ovid Therapeutics	$18,658,070		0.0%	6,117,400	0.5%	Medical
VERV Verve Therapeutics	$16,600,000		0.0%	1,250,000	0.4%	Medical
KROS Keros Therapeutics	$12,412,500	$12,412,500 ▲	New Holding	187,500	0.3%	Medical
DYNE THERAPEUTICS INC	$12,123,637	$12,123,637 ▲	New Holding	427,039	0.3%	COM
KYVERNA THERAPEUTICS INC	$11,178,000	$11,178,000 ▲	New Holding	450,000	0.3%	COM ADDED
GOSS Gossamer Bio	$10,850,577		0.0%	9,195,404	0.3%	Medical
KOD Kodiak Sciences	$8,756,322	$8,756,322 ▲	New Holding	1,664,700	0.2%	Medical
ALVR AlloVir	$8,526,282	$8,526,282 ▲	New Holding	11,294,585	0.2%	Medical
GBIO Generation Bio	$8,330,749		0.0%	2,046,867	0.2%	Medical
ATRA Atara Biotherapeutics	$7,055,928	$69,400 ▲	1.0%	10,167,043	0.2%	Medical
PRQR ProQR Therapeutics	$6,604,889	$219,050 ▼	-3.2%	2,884,357	0.2%	Medical
ALGS Aligos Therapeutics	$6,261,679		0.0%	6,389,468	0.2%	Medical
ARQT Arcutis Biotherapeutics	$4,955,000	$4,955,000 ▲	New Holding	500,000	0.1%	Medical
PRME Prime Medicine	$4,900,000	$4,900,000 ▲	New Holding	700,000	0.1%	Medical
NUVATION BIO INC	$3,506,532		0.0%	963,333	0.1%	*W EXP 07/07/202
HOOK Hookipa Pharma	$3,271,657		0.0%	4,595,024	0.1%	Medical
SRZNW Surrozen	$1,047,307		0.0%	66,665	0.0%	Medical
PMVP PMV Pharmaceuticals	$963,694		0.0%	566,879	0.0%	Medical
CMAXW CareMax	$482,000		0.0%	100,000	0.0%	Medical
ALPN Alpine Immune Sciences	$39,640	$39,640 ▲	New Holding	1,000	0.0%	Medical
MRTX Mirati Therapeutics	$0	$434,572,516 ▼	-100.0%	0	0.0%	Medical
ARGX argenx	$0	$114,508,289 ▼	-100.0%	0	0.0%	Medical
GRPH Graphite Bio	$0	$22,370,729 ▼	-100.0%	0	0.0%	Medical
SPYRE THERAPEUTICS INC	$0	$19,089,876 ▼	-100.0%	0	0.0%	COM NEW
RVMD Revolution Medicines	$0	$3,802,366 ▼	-100.0%	0	0.0%	Medical
NGM NGM Biopharmaceuticals	$0	$2,049,465 ▼	-100.0%	0	0.0%	Medical
ALLK Allakos	$0	$2,044,497 ▼	-100.0%	0	0.0%	Medical
TYRA Tyra Biosciences	$0	$1,897,644 ▼	-100.0%	0	0.0%	Medical
PHAT Phathom Pharmaceuticals	$0	$1,812,122 ▼	-100.0%	0	0.0%	Medical
NAMSW NewAmsterdam Pharma	$0	$744,648 ▼	-100.0%	0	0.0%	Medical