Ikarian Capital, LLC Top Holdings and 13F Report (2024)

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About Ikarian Capital, LLC

Investment Activity

Ikarian Capital, LLC has $912.05 million in total holdings as of March 31, 2024.
Ikarian Capital, LLC owns shares of 100 different stocks, but just 33 companies or ETFs make up 80% of its holdings.
Approximately 34.70% of the portfolio was purchased this quarter.
About 59.11% of the portfolio was sold this quarter.
This quarter, Ikarian Capital, LLC has purchased 101 new stocks and bought additional shares in 32 stocks.
Ikarian Capital, LLC sold shares of 31 stocks and completely divested from 27 stocks this quarter.

Largest Holdings

Krystal Biotech: $84,516,750
SPDR S&P Biotech ETF: $66,423,000
Alnylam Pharmaceuticals: $46,186,177
Crinetics Pharmaceuticals: $44,602,955
Sarepta Therapeutics: $34,744,216

Largest New Holdings this Quarter

AstraZeneca: $20,948,300 Holding
4D Molecular Therapeutics: $16,414,272 Holding
Viking Therapeutics: $16,400,000 Holding
Madrigal Pharmaceuticals: $13,725,856 Holding
MacroGenics: $12,389,338 Holding

Largest Purchases this Quarter

AstraZeneca: 309,200 shares (about $20.95M)
Corcept Therapeutics: 731,400 shares (about $18.42M)
Disc Medicine: 276,590 shares (about $17.22M)
4D Molecular Therapeutics: 515,200 shares (about $16.41M)
Viking Therapeutics: 200,000 shares (about $16.40M)

Largest Sales this Quarter

Cytokinetics: 391,853 shares (about $27.47M)
Nuvalent: 309,341 shares (about $23.23M)
Longboard Pharmaceuticals: 979,226 shares (about $21.15M)
Sarepta Therapeutics: 148,662 shares (about $19.25M)
Immunovant: 421,869 shares (about $13.63M)

Sector Allocation Over Time

Selling

Neutral

Buying

Latest 13F Holdings and Changes Since Previous Quarterly Filing

Issuer Name	Holdings Value	Approximate Purchase/Sale	Change in Shares	Shares Held	% of Portfolio	Sector
KRYS Krystal Biotech	$84,516,750	$6,583,410 ▼	-7.2%	475,000	9.3%	Medical
XBI SPDR S&P Biotech ETF	$66,423,000	$14,233,500 ▲	27.3%	700,000	7.3%	ETF
ALNY Alnylam Pharmaceuticals	$46,186,177	$6,088,742 ▲	15.2%	309,041	5.1%	Medical
CRNX Crinetics Pharmaceuticals	$44,602,955	$8,073,836 ▲	22.1%	952,851	4.9%	Medical
SRPT Sarepta Therapeutics	$34,744,216	$19,245,783 ▼	-35.6%	268,378	3.8%	Medical
CORT Corcept Therapeutics	$32,092,060	$18,423,966 ▲	134.8%	1,274,000	3.5%	Medical
TARS Tarsus Pharmaceuticals	$29,453,568	$6,970,403 ▲	31.0%	810,277	3.2%	Medical
IRON Disc Medicine	$29,360,072	$17,220,493 ▲	141.9%	471,572	3.2%	Medical
SLNO Soleno Therapeutics	$27,670,671	$1,500,910 ▲	5.7%	646,511	3.0%	Medical
CRBP Corbus Pharmaceuticals	$21,945,794	$14,258,717 ▲	185.5%	559,271	2.4%	Medical
AZN AstraZeneca	$20,948,300	$20,948,300 ▲	New Holding	309,200	2.3%	Medical
BBIO BridgeBio Pharma	$20,760,090	$6,131,034 ▲	41.9%	671,413	2.3%	Medical
EYPT EyePoint Pharmaceuticals	$17,894,991	$3,649,971 ▼	-16.9%	865,747	2.0%	Medical
BMEA Biomea Fusion	$17,649,970	$1,450,150 ▼	-7.6%	1,180,600	1.9%	Medical
CYTK Cytokinetics	$17,187,256	$27,472,814 ▼	-61.5%	245,147	1.9%	Medical
AMGN Amgen	$17,059,200	$7,108,000 ▲	71.4%	60,000	1.9%	Medical
FDMT 4D Molecular Therapeutics	$16,414,272	$16,414,272 ▲	New Holding	515,200	1.8%	Medical
VKTX Viking Therapeutics	$16,400,000	$16,400,000 ▲	New Holding	200,000	1.8%	Medical
ALPN Alpine Immune Sciences	$14,443,428	$4,871,082 ▼	-25.2%	364,365	1.6%	Medical
MDGL Madrigal Pharmaceuticals	$13,725,856	$13,725,856 ▲	New Holding	51,400	1.5%	Medical
INSM Insmed	$12,735,771	$12,730,345 ▲	234,617.5%	469,435	1.4%	Medical
MGNX MacroGenics	$12,389,338	$12,389,338 ▲	New Holding	841,667	1.4%	Medical
BHVN Biohaven	$12,234,153	$12,234,153 ▲	New Holding	223,700	1.3%	Medical
SRRK Scholar Rock	$11,615,058	$11,615,058 ▲	New Holding	654,001	1.3%	Medical
PRAXIS PRECISION MEDICINES I	$11,605,272	$598,728 ▼	-4.9%	190,188	1.3%	COM NEW
AVTE Aerovate Therapeutics	$10,880,725	$10,880,725 ▲	New Holding	367,965	1.2%	Medical
LNTH Lantheus	$10,580,800	$7,157,600 ▼	-40.4%	170,000	1.2%	Medical
SLRN Acelyrin	$10,559,295	$5,154,064 ▼	-32.8%	1,564,340	1.2%	Medical
ANNX Annexon	$10,073,850	$8,926,650 ▼	-47.0%	1,405,000	1.1%	Medical
ATXS Astria Therapeutics	$9,773,499	$4,498,089 ▲	85.3%	694,387	1.1%	Medical
MRNS Marinus Pharmaceuticals	$9,522,058	$2,777,594 ▲	41.2%	1,053,325	1.0%	Medical
ARE Alexandria Real Estate Equities	$9,449,103		0.0%	73,300	1.0%	Finance
IMVT Immunovant	$8,947,446	$13,630,586 ▼	-60.4%	276,925	1.0%	Medical
CPRX Catalyst Pharmaceuticals	$8,263,073	$199,633 ▲	2.5%	518,386	0.9%	Medical
RCKT Rocket Pharmaceuticals	$8,003,767	$2,495,452 ▼	-23.8%	297,096	0.9%	Medical
APLS Apellis Pharmaceuticals	$7,940,708	$2,896,032 ▼	-26.7%	135,092	0.9%	Medical
MLTX MoonLake Immunotherapeutics	$7,936,340	$2,139,798 ▼	-21.2%	158,000	0.9%	Medical
NUVL Nuvalent	$7,629,219	$23,228,415 ▼	-75.3%	101,601	0.8%	Medical
PYXS Pyxis Oncology	$7,081,858	$7,081,858 ▲	New Holding	1,662,408	0.8%	Medical
ABEO Abeona Therapeutics	$6,931,674	$2,581,674 ▲	59.3%	956,093	0.8%	Medical
TOURMALINE BIO INC	$6,587,940	$6,587,940 ▲	New Holding	287,683	0.7%	COM
LYRA Lyra Therapeutics	$6,573,477	$1,228,792 ▼	-15.7%	1,056,829	0.7%	Medical
VRNA Verona Pharma	$6,038,738	$126,178 ▲	2.1%	375,310	0.7%	Medical
ANVS Annovis Bio	$5,972,610	$5,932,150 ▲	14,661.8%	501,900	0.7%	Medical
ARQT Arcutis Biotherapeutics	$5,843,352	$5,843,352 ▲	New Holding	589,642	0.6%	Medical
CYBN Cybin	$5,769,768	$5,769,768 ▲	New Holding	13,953,488	0.6%	Medical
CERVOMED INC	$5,530,138	$5,530,138 ▲	New Holding	237,345	0.6%	COM
GPCR Structure Therapeutics	$5,246,064	$4,623,565 ▲	742.7%	122,400	0.6%	Medical
XENE Xenon Pharmaceuticals	$4,614,400	$2,019,131 ▼	-30.4%	107,187	0.5%	Medical
AMLX Amylyx Pharmaceuticals	$4,481,381	$1,698,175 ▼	-27.5%	1,577,951	0.5%	Medical
NRIX Nurix Therapeutics	$4,410,000	$4,410,000 ▲	New Holding	300,000	0.5%	Medical
RAPT RAPT Therapeutics	$4,382,464	$3,854,440 ▲	730.0%	488,025	0.5%	Medical
WVE Wave Life Sciences	$3,640,843	$3,640,843 ▲	New Holding	590,088	0.4%	Medical
CABA Cabaletta Bio	$3,412,000	$3,695,537 ▼	-52.0%	200,000	0.4%	Medical
LRMR Larimar Therapeutics	$3,328,427	$1,247,340 ▼	-27.3%	438,528	0.4%	Medical
VRDN Viridian Therapeutics	$3,132,539	$3,132,539 ▲	New Holding	178,900	0.3%	Medical
JASPER THERAPEUTICS INC	$3,087,939	$3,087,939 ▲	New Holding	105,175	0.3%	COM NEW
AEON BIOPHARMA INC	$2,992,534		0.0%	257,977	0.3%	CL A
MNMD Mind Medicine (MindMed)	$2,796,321	$2,843,678 ▼	-50.4%	297,481	0.3%	Medical
VTYX Ventyx Biosciences	$2,792,059	$2,759,532 ▲	8,483.8%	507,647	0.3%	Medical
KOD Kodiak Sciences	$2,506,842	$335,088 ▲	15.4%	476,586	0.3%	Medical
QURE uniQure	$2,439,492	$1,621,194 ▲	198.1%	469,133	0.3%	Medical
IBIO INC	$2,436,000	$2,436,000 ▲	New Holding	600,000	0.3%	CON NEW
NUVB Nuvation Bio	$2,305,146	$2,146,034 ▼	-48.2%	633,282	0.3%	Medical
SAGIMET BIOSCIENCES INC	$2,236,103	$2,236,103 ▲	New Holding	412,565	0.2%	COM SER A
IMUX Immunic	$2,128,339	$1,534,339 ▲	258.3%	1,612,378	0.2%	Medical
LENZ THERAPEUTICS INC	$1,898,050	$1,898,050 ▲	New Holding	85,000	0.2%	COM
ACHL Achilles Therapeutics	$1,803,976	$1,803,976 ▲	New Holding	1,443,181	0.2%	Medical
VYGR Voyager Therapeutics	$1,683,779	$1,163,750 ▼	-40.9%	180,857	0.2%	Medical
ITOS iTeos Therapeutics	$1,382,073	$3,343,791 ▼	-70.8%	101,325	0.2%	Medical
ALLK Allakos	$1,175,171	$876,480 ▲	293.4%	932,675	0.1%	Medical
PRQR ProQR Therapeutics	$1,097,734	$24,875 ▲	2.3%	483,583	0.1%	Medical
IFRX InflaRx	$1,085,680	$25,230 ▲	2.4%	704,987	0.1%	Medical
ABOS Acumen Pharmaceuticals	$1,079,063	$197,762 ▼	-15.5%	266,435	0.1%	Medical
ROIV Roivant Sciences	$1,060,419	$539,775 ▼	-33.7%	100,609	0.1%	Medical
GLYC GlycoMimetics	$1,036,800	$1,036,800 ▲	New Holding	345,600	0.1%	Medical
AVALO THERAPEUTICS INC	$1,014,594	$1,014,594 ▲	New Holding	46,648	0.1%	COM NEW
AVRO AVROBIO	$965,198	$45,827 ▲	5.0%	754,061	0.1%	Medical
MIST Milestone Pharmaceuticals	$834,174	$5,712 ▲	0.7%	466,019	0.1%	Medical
TARA Protara Therapeutics	$812,830	$56,288 ▲	7.4%	202,701	0.1%	Medical
KZR Kezar Life Sciences	$783,484	$14,066 ▲	1.8%	868,992	0.1%	Medical
ELEV Elevation Oncology	$759,697	$5,252,353 ▼	-87.4%	148,089	0.1%	Medical
NYXH Nyxoah	$683,929	$683,929 ▲	New Holding	50,699	0.1%	Medical
VERU Veru	$662,563	$662,563 ▲	New Holding	946,382	0.1%	Medical
KPTI Karyopharm Therapeutics	$618,126	$14,126 ▲	2.3%	409,355	0.1%	Medical
TERN Terns Pharmaceuticals	$580,540	$505,008 ▼	-46.5%	88,497	0.1%	Medical
IMTX Immatics	$519,351	$4,036 ▲	0.8%	49,415	0.1%	Medical
ANEB Anebulo Pharmaceuticals	$453,064		0.0%	157,862	0.0%	Medical
TPST Tempest Therapeutics	$412,895		0.0%	105,600	0.0%	Medical
Q32 BIO INC	$380,588	$380,588 ▲	New Holding	22,335	0.0%	COM
HOOK Hookipa Pharma	$377,913		0.0%	530,776	0.0%	Medical
RLMD Relmada Therapeutics	$187,717		0.0%	40,369	0.0%	Medical
CMMB Chemomab Therapeutics	$166,232		0.0%	213,392	0.0%	Medical
STOK Stoke Therapeutics	$92,017	$71,551 ▼	-43.7%	6,816	0.0%	Medical
BCLI Brainstorm Cell Therapeutics	$50,960		0.0%	90,242	0.0%	Medical
SYNLOGIC INC	$36,602		0.0%	20,448	0.0%	COM NEW
FNCH Finch Therapeutics Group	$18,126		0.0%	6,892	0.0%	Medical
TYRA Tyra Biosciences	$8,216	$781,734 ▼	-99.0%	501	0.0%	Medical
ASLN ASLAN Pharmaceuticals	$6,273		0.0%	35,420	0.0%	Medical
LBPH Longboard Pharmaceuticals	$5,098	$21,152,941 ▼	-100.0%	236	0.0%	Medical

Showing largest 100 holdings. View all holdings.

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Ikarian Capital, LLC Top Holdings and 13F Report (2024)

About Ikarian Capital, LLC

Investment Activity

Largest Holdings

Largest New Holdings this Quarter

Largest Purchases this Quarter

Largest Sales this Quarter

Sector Allocation Over Time

Latest 13F Holdings and Changes Since Previous Quarterly Filing

More Institutional Buying and Selling Information

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Ikarian Capital, LLC Top Holdings and 13F Report (2024)

About Ikarian Capital, LLC

Investment Activity

Largest Holdings

Largest New Holdings this Quarter

Largest Purchases this Quarter

Largest Sales this Quarter

Sector Allocation Over Time

Map of 500 Largest Holdings ofIkarian Capital, LLC

Latest 13F Holdings and Changes Since Previous Quarterly Filing

More Institutional Buying and Selling Information