Samsara Biocapital, LLC Top Holdings and 13F Report (2024)

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About Samsara Biocapital, LLC

Investment Activity

Samsara Biocapital, LLC has $646.37 million in total holdings as of March 31, 2024.
Samsara Biocapital, LLC owns shares of 39 different stocks, but just 12 companies or ETFs make up 80% of its holdings.
Approximately 10.49% of the portfolio was purchased this quarter.
About 23.18% of the portfolio was sold this quarter.
This quarter, Samsara Biocapital, LLC has purchased 41 new stocks and bought additional shares in 4 stocks.
Samsara Biocapital, LLC sold shares of 2 stocks and completely divested from 5 stocks this quarter.

Largest Holdings

Scholar Rock: $120,565,696
CARGO THERAPEUTICS INC: $91,996,098
Mineralys Therapeutics: $65,517,166
NEUROGENE INC: $64,530,511
Nkarta: $40,732,458

Largest New Holdings this Quarter

LENZ THERAPEUTICS INC: $26,985,202 Holding
JASPER THERAPEUTICS INC: $15,414,000 Holding
ADVERUM BIOTECHNOLOGIES INC: $4,124,157 Holding

Largest Purchases this Quarter

LENZ THERAPEUTICS INC: 1,208,473 shares (about $26.99M)
JASPER THERAPEUTICS INC: 525,000 shares (about $15.41M)
Nkarta: 900,000 shares (about $9.73M)
Mineralys Therapeutics: 555,555 shares (about $7.17M)
ADVERUM BIOTECHNOLOGIES INC: 291,666 shares (about $4.12M)

Largest Sales this Quarter

Janux Therapeutics: 180,207 shares (about $6.78M)
Arcellx: 6,800 shares (about $472.94K)

Sector Allocation Over Time

Selling

Neutral

Buying

Latest 13F Holdings and Changes Since Previous Quarterly Filing

Issuer Name	Holdings Value	Approximate Purchase/Sale	Change in Shares	Shares Held	% of Portfolio	Sector
SRRK Scholar Rock	$120,565,696		0.0%	6,788,609	18.7%	Medical
CARGO THERAPEUTICS INC	$91,996,098		0.0%	4,121,689	14.2%	COM
MLYS Mineralys Therapeutics	$65,517,166	$7,172,215 ▲	12.3%	5,074,916	10.1%	Medical
NEUROGENE INC	$64,530,511		0.0%	1,267,790	10.0%	COM
NKTX Nkarta	$40,732,458	$9,729,000 ▲	31.4%	3,768,035	6.3%	Medical
ACLX Arcellx	$31,550,732	$472,940 ▼	-1.5%	453,641	4.9%	Medical
LENZ THERAPEUTICS INC	$26,985,202	$26,985,202 ▲	New Holding	1,208,473	4.2%	COM
LYRA Lyra Therapeutics	$17,293,223		0.0%	2,780,261	2.7%	Medical
SLRN Acelyrin	$17,030,399		0.0%	2,523,022	2.6%	Medical
AVDL Avadel Pharmaceuticals	$16,341,531		0.0%	967,527	2.5%	Medical
JASPER THERAPEUTICS INC	$15,414,000	$15,414,000 ▲	New Holding	525,000	2.4%	COM NEW
ZYME Zymeworks	$15,347,365		0.0%	1,458,875	2.4%	Medical
HLVX HilleVax	$13,291,927		0.0%	799,274	2.1%	Medical
ABIVAX SA	$12,155,000		0.0%	850,000	1.9%	SPONSORED ADS
INZY Inozyme Pharma	$11,968,750		0.0%	1,562,500	1.9%	Medical
SYRS Syros Pharmaceuticals	$9,557,384		0.0%	1,786,427	1.5%	Medical
STRO Sutro Biopharma	$9,467,021		0.0%	1,675,579	1.5%	Medical
RYTM Rhythm Pharmaceuticals	$7,480,795		0.0%	172,647	1.2%	Medical
GOSS Gossamer Bio	$7,233,716		0.0%	6,130,268	1.1%	Medical
JANX Janux Therapeutics	$6,784,794	$6,784,794 ▼	-50.0%	180,207	1.0%	Medical
IOBT IO Biotech	$6,297,226		0.0%	3,640,015	1.0%	Medical
VRNA Verona Pharma	$5,591,275		0.0%	347,500	0.9%	Medical
TNGX Tango Therapeutics	$5,002,200		0.0%	630,000	0.8%	Medical
VTV THERAPEUTICS INC	$4,865,628	$3,903,533 ▲	405.7%	206,784	0.8%	CL A NEW
IMTX Immatics	$4,161,960		0.0%	396,000	0.6%	Medical
ADVERUM BIOTECHNOLOGIES INC	$4,124,157	$4,124,157 ▲	New Holding	291,666	0.6%	COM NEW
PRME Prime Medicine	$3,782,128	$490,000 ▲	14.9%	540,304	0.6%	Medical
DAWN Day One Biopharmaceuticals	$3,244,941		0.0%	196,425	0.5%	Medical
LPTX Leap Therapeutics	$1,780,346		0.0%	669,303	0.3%	Medical
IGMS IGM Biosciences	$1,492,508		0.0%	154,664	0.2%	Medical
BOLT Bolt Biotherapeutics	$1,468,814		0.0%	1,049,153	0.2%	Medical
TERN Terns Pharmaceuticals	$1,327,403		0.0%	202,348	0.2%	Medical
ACRS Aclaris Therapeutics	$863,252		0.0%	696,171	0.1%	Medical
VIRX Viracta Therapeutics	$703,503		0.0%	689,709	0.1%	Medical
ALLK Allakos	$216,832		0.0%	172,089	0.0%	Medical
KRON Kronos Bio	$101,570		0.0%	78,131	0.0%	Medical
ALVR AlloVir	$62,155		0.0%	82,336	0.0%	Medical
NUVATION BIO INC	$40,333		0.0%	133,333	0.0%	*W EXP 07/07/202
SRZNW Surrozen	$3,020		0.0%	99,999	0.0%	Medical
RAYZEBIO INC	$0	$114,762,587 ▼	-100.0%	0	0.0%	COM
GRPH Graphite Bio	$0	$22,163,403 ▼	-100.0%	0	0.0%	Medical
PEPG PepGen	$0	$2,970,328 ▼	-100.0%	0	0.0%	Medical
RAIN Rain Oncology	$0	$2,441,462 ▼	-100.0%	0	0.0%	Medical
SCIENCE 37 HOLDINGS INC	$0	$240,300 ▼	-100.0%	0	0.0%	COM NEW