Silverarc Capital Management, LLC Top Holdings and 13F Report (2024)

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About Silverarc Capital Management, LLC

Investment Activity

Silverarc Capital Management, LLC has $360.05 million in total holdings as of March 31, 2024.
Silverarc Capital Management, LLC owns shares of 77 different stocks, but just 32 companies or ETFs make up 80% of its holdings.
Approximately 36.59% of the portfolio was purchased this quarter.
About 37.97% of the portfolio was sold this quarter.
This quarter, Silverarc Capital Management, LLC has purchased 65 new stocks and bought additional shares in 10 stocks.
Silverarc Capital Management, LLC sold shares of 30 stocks and completely divested from 22 stocks this quarter.

Largest Holdings

Merus: $25,499,904
Solid Biosciences: $17,649,866
Morphic: $17,035,814
ORIC Pharmaceuticals: $15,303,846
Mersana Therapeutics: $13,300,215

Largest New Holdings this Quarter

Avidity Biosciences: $12,487,013 Holding
C4 Therapeutics: $11,731,556 Holding
PERSPECTIVE THERAPEUTICS INC: $9,648,649 Holding
Crinetics Pharmaceuticals: $5,983,956 Holding
HELIX ACQUISITION CORP II: $5,200,000 Holding

Largest Purchases this Quarter

Avidity Biosciences: 489,303 shares (about $12.49M)
Mersana Therapeutics: 2,667,198 shares (about $11.95M)
C4 Therapeutics: 1,435,931 shares (about $11.73M)
Solid Biosciences: 730,210 shares (about $9.73M)
PERSPECTIVE THERAPEUTICS INC: 8,108,108 shares (about $9.65M)

Largest Sales this Quarter

MacroGenics: 780,562 shares (about $11.49M)
Rocket Pharmaceuticals: 281,670 shares (about $7.59M)
PRAXIS PRECISION MEDICINES I: 93,285 shares (about $5.69M)
Xenon Pharmaceuticals: 97,078 shares (about $4.18M)
Alpine Immune Sciences: 98,769 shares (about $3.92M)

Sector Allocation Over Time

Selling

Neutral

Buying

Latest 13F Holdings and Changes Since Previous Quarterly Filing

Issuer Name	Holdings Value	Approximate Purchase/Sale	Change in Shares	Shares Held	% of Portfolio	Sector
MRUS Merus	$25,499,904	$3,570,609 ▼	-12.3%	566,287	7.1%	Medical
SLDB Solid Biosciences	$17,649,866	$9,726,397 ▲	122.8%	1,325,065	4.9%	Medical
MORF Morphic	$17,035,814	$565,664 ▼	-3.2%	483,972	4.7%	Medical
ORIC ORIC Pharmaceuticals	$15,303,846	$783,654 ▼	-4.9%	1,113,007	4.3%	Medical
MRSN Mersana Therapeutics	$13,300,215	$11,949,047 ▲	884.3%	2,968,798	3.7%	Medical
CLDX Celldex Therapeutics	$12,562,293	$2,186,679 ▲	21.1%	299,316	3.5%	Medical
RNA Avidity Biosciences	$12,487,013	$12,487,013 ▲	New Holding	489,303	3.5%	Medical
NUVL Nuvalent	$11,845,448	$2,646,923 ▼	-18.3%	157,750	3.3%	Medical
CCCC C4 Therapeutics	$11,731,556	$11,731,556 ▲	New Holding	1,435,931	3.3%	Medical
PRAXIS PRECISION MEDICINES I	$11,627,727	$5,692,251 ▼	-32.9%	190,556	3.2%	COM NEW
PSTX Poseida Therapeutics	$11,472,758	$348,677 ▼	-2.9%	3,596,476	3.2%	Medical
AKRO Akero Therapeutics	$10,102,712	$3,806,556 ▲	60.5%	399,949	2.8%	Medical
PERSPECTIVE THERAPEUTICS INC	$9,648,649	$9,648,649 ▲	New Holding	8,108,108	2.7%	COM
RYTM Rhythm Pharmaceuticals	$7,963,014	$412,848 ▲	5.5%	183,776	2.2%	Medical
ALPN Alpine Immune Sciences	$7,889,153	$3,915,203 ▼	-33.2%	199,020	2.2%	Medical
URGN UroGen Pharma	$7,628,805	$252,255 ▼	-3.2%	508,587	2.1%	Medical
GOSS Gossamer Bio	$7,233,716		0.0%	6,130,268	2.0%	Medical
MGNX MacroGenics	$7,037,323	$11,489,873 ▼	-62.0%	478,079	2.0%	Medical
COGT Cogent Biosciences	$6,966,402	$469,856 ▲	7.2%	1,036,667	1.9%	Medical
KALV KalVista Pharmaceuticals	$6,655,630	$5,330,465 ▲	402.2%	561,183	1.8%	Medical
KOD Kodiak Sciences	$6,516,204	$1,256,204 ▲	23.9%	1,238,822	1.8%	Medical
VCYT Veracyte	$6,221,930	$732,388 ▲	13.3%	280,773	1.7%	Medical
CRNX Crinetics Pharmaceuticals	$5,983,956	$5,983,956 ▲	New Holding	127,835	1.7%	Medical
OLMA Olema Pharmaceuticals	$5,833,388	$662,367 ▼	-10.2%	515,317	1.6%	Medical
HELIX ACQUISITION CORP II	$5,200,000	$5,200,000 ▲	New Holding	500,000	1.4%	CL A ORD SHS
EYPT EyePoint Pharmaceuticals	$5,125,499	$5,125,499 ▲	New Holding	247,968	1.4%	Medical
BOUNDLESS BIO INC	$4,453,125	$4,453,125 ▲	New Holding	312,500	1.2%	COM
TELA TELA Bio	$4,404,745	$103,358 ▼	-2.3%	776,851	1.2%	Medical
BIIB Biogen	$4,175,675	$136,925 ▼	-3.2%	19,365	1.2%	Medical
FULC Fulcrum Therapeutics	$3,761,236	$3,761,236 ▲	New Holding	398,436	1.0%	Medical
SRRK Scholar Rock	$3,541,610	$1,253,589 ▼	-26.1%	199,415	1.0%	Medical
CYTK Cytokinetics	$3,505,500	$3,505,500 ▲	New Holding	50,000	1.0%	Medical
APOGEE THERAPEUTICS INC	$3,322,500	$3,322,500 ▲	New Holding	50,000	0.9%	COM
JASPER THERAPEUTICS INC	$3,226,429	$3,226,429 ▲	New Holding	109,892	0.9%	COM NEW
INSM Insmed	$3,082,402	$1,136,421 ▼	-26.9%	113,616	0.9%	Medical
WVE Wave Life Sciences	$3,057,056	$3,057,056 ▲	New Holding	495,471	0.8%	Medical
TRVI Trevi Therapeutics	$2,912,611	$67,786 ▼	-2.3%	844,235	0.8%	Medical
XENE Xenon Pharmaceuticals	$2,845,175	$4,179,209 ▼	-59.5%	66,090	0.8%	Medical
DXCM DexCom	$2,774,000	$1,525,700 ▼	-35.5%	20,000	0.8%	Medical
CERS Cerus	$2,770,256	$64,462 ▼	-2.3%	1,465,744	0.8%	Medical
PLRX Pliant Therapeutics	$2,732,541	$2,013,467 ▼	-42.4%	183,392	0.8%	Medical
RCKT Rocket Pharmaceuticals	$2,720,994	$7,588,190 ▼	-73.6%	101,002	0.8%	Medical
CGEN Compugen	$2,580,000	$154,800 ▲	6.4%	1,000,000	0.7%	Medical
ITCI Intra-Cellular Therapies	$2,408,644	$3,127,355 ▼	-56.5%	34,807	0.7%	Medical
NAMS NewAmsterdam Pharma	$2,355,824	$2,355,824 ▲	New Holding	99,612	0.7%	Medical
EVGN Evogene	$2,314,127	$10,873 ▼	-0.5%	3,085,503	0.6%	Medical
ADCT ADC Therapeutics	$2,250,487	$2,250,487 ▲	New Holding	501,222	0.6%	Medical
VRNA Verona Pharma	$2,199,728	$2,199,728 ▲	New Holding	136,714	0.6%	Medical
MACROGENICS INC	$2,141,760	$2,141,760 ▲	New Holding	145,500	0.6%	CALL
MIRM Mirum Pharmaceuticals	$1,989,353	$40,619 ▼	-2.0%	79,194	0.6%	Medical
KRYS Krystal Biotech	$1,779,300	$1,779,300 ▲	New Holding	10,000	0.5%	Medical
MODD Modular Medical	$1,665,000	$1,665,000 ▲	New Holding	900,000	0.5%	Medical
TERN Terns Pharmaceuticals	$1,643,615	$1,747,899 ▼	-51.5%	250,551	0.5%	Medical
VKTX Viking Therapeutics	$1,640,000	$1,640,000 ▲	New Holding	20,000	0.5%	Medical
AMLX Amylyx Pharmaceuticals	$1,420,000	$1,420,000 ▲	New Holding	500,000	0.4%	Medical
CRBP Corbus Pharmaceuticals	$1,254,895	$1,254,895 ▲	New Holding	31,980	0.3%	Medical
FRACTYL HEALTH INC	$1,233,328	$1,233,328 ▲	New Holding	166,666	0.3%	COM
C4 THERAPEUTICS INC	$1,225,500	$1,225,500 ▲	New Holding	150,000	0.3%	CALL
ETNB 89bio	$1,074,349	$773,141 ▼	-41.8%	92,298	0.3%	Medical
ABIVAX SA	$1,072,500	$1,072,500 ▲	New Holding	75,000	0.3%	SPONSORED ADS
ZURA Zura Bio	$844,255	$345,647 ▼	-29.0%	328,504	0.2%	Medical
KPTI Karyopharm Therapeutics	$843,284	$5,268 ▼	-0.6%	558,466	0.2%	Medical
GERN Geron	$825,000	$825,000 ▲	New Holding	250,000	0.2%	Medical
MOLECULAR TEMPLATES INC	$794,322		0.0%	354,608	0.2%	COM NEW
ACET Adicet Bio	$778,506	$778,506 ▲	New Holding	331,279	0.2%	Medical
MLYS Mineralys Therapeutics	$735,147	$735,147 ▲	New Holding	56,944	0.2%	Medical
ALGS Aligos Therapeutics	$642,405	$12,737 ▼	-1.9%	655,515	0.2%	Medical
RLMD Relmada Therapeutics	$462,112	$2,888 ▼	-0.6%	99,379	0.1%	Medical
ERAS Erasca	$461,121	$461,121 ▲	New Holding	223,845	0.1%	Medical
GPCR Structure Therapeutics	$428,600	$428,600 ▲	New Holding	10,000	0.1%	Medical
RZLT Rezolute	$387,562	$13,005 ▼	-3.2%	151,985	0.1%	Medical
VYNE VYNE Therapeutics	$265,196	$265,196 ▲	New Holding	86,383	0.1%	Medical
ELUT Elutia	$247,527	$247,527 ▲	New Holding	78,580	0.1%	Medical
IMNM Immunome	$184,829	$184,829 ▲	New Holding	7,489	0.1%	Medical
AMYLYX PHARMACEUTICALS INC	$56,800	$56,800 ▲	New Holding	20,000	0.0%	CALL
RCKTW Rocket Pharmaceuticals	$31,365		0.0%	104,828	0.0%	Medical
MERSANA THERAPEUTICS INC	$7,616	$7,616 ▲	New Holding	1,700	0.0%	CALL
MDT Medtronic	$0	$11,121,300 ▼	-100.0%	0	0.0%	Medical
SNY Sanofi	$0	$10,940,600 ▼	-100.0%	0	0.0%	Medical
MRTX Mirati Therapeutics	$0	$8,812,500 ▼	-100.0%	0	0.0%	Medical
ISRG Intuitive Surgical	$0	$5,332,987 ▼	-100.0%	0	0.0%	Medical
CBAY CymaBay Therapeutics	$0	$5,172,190 ▼	-100.0%	0	0.0%	Medical
CRBU Caribou Biosciences	$0	$5,161,687 ▼	-100.0%	0	0.0%	Medical
PEN Penumbra	$0	$5,030,800 ▼	-100.0%	0	0.0%	Medical
SRPT Sarepta Therapeutics	$0	$4,521,024 ▼	-100.0%	0	0.0%	Medical
UTHR United Therapeutics	$0	$3,597,400 ▼	-100.0%	0	0.0%	Medical
BHVN Biohaven	$0	$3,025,746 ▼	-100.0%	0	0.0%	Medical
MLTX MoonLake Immunotherapeutics	$0	$3,019,500 ▼	-100.0%	0	0.0%	Medical
SLNO Soleno Therapeutics	$0	$2,965,016 ▼	-100.0%	0	0.0%	Medical
ANNX Annexon	$0	$1,895,128 ▼	-100.0%	0	0.0%	Medical
ARGX argenx	$0	$1,835,955 ▼	-100.0%	0	0.0%	Medical
PMVP PMV Pharmaceuticals	$0	$1,705,000 ▼	-100.0%	0	0.0%	Medical
ALT Altimmune	$0	$1,687,500 ▼	-100.0%	0	0.0%	Medical
NTLA Intellia Therapeutics	$0	$1,671,523 ▼	-100.0%	0	0.0%	Medical
BCRX BioCryst Pharmaceuticals	$0	$1,489,881 ▼	-100.0%	0	0.0%	Medical
SDGR Schrödinger	$0	$1,113,989 ▼	-100.0%	0	0.0%	Medical
VRDN Viridian Therapeutics	$0	$1,098,540 ▼	-100.0%	0	0.0%	Medical
IMVT Immunovant	$0	$842,600 ▼	-100.0%	0	0.0%	Medical
APLS Apellis Pharmaceuticals	$0	$598,600 ▼	-100.0%	0	0.0%	Medical