Spark Therapeutics, Inc. focuses on the development of gene therapy products for patients suffering from debilitating genetic diseases. Its products include LUXTURNA (voretigene neparvovec) for the treatment of patients with confirmed biallelic RPE65 mutation-associated retinal dystrophy and viable retinal cells. The company's gene therapy product candidates comprise SPK-8011 and SPK-8016 for hemophilia; SPK-7001 for choroideremia; and SPK-9001 for hemophilia B. It is also developing other liver-directed gene therapies, including SPK-3006 for Pompe disease; and neurodegenerative disease product candidates to address Huntington's disease and others, as well as TPP1 deficiency, which is a form of Batten disease. The company's preclinical programs targets inherited retinal diseases, including Stargardt's disease. The company has collaboration agreement with Pfizer, Inc. for the development and commercialization of SPK-FIX product candidates in its gene therapy program for the treatment of hemophilia B. It also has licensing and commercialization agreement with Novartis to develop and commercialize voretigene neparvovec outside the United States. Spark Therapeutics, Inc. was founded in 2013 and is headquartered in Philadelphia, Pennsylvania.
Industry, Sector and Symbol
Industry Biological products, except diagnostic
Sub-IndustryN/A
SectorMedical
Phone888-772-7560
Debt
Price-To-Earnings
Sales & Book Value
Annual Sales$64.72 million
Profitability
Miscellaneous
Employees368
Next Earnings Date5/14/2019 (Estimated)
OptionableOptionable
Spark Therapeutics (NASDAQ:ONCE) Frequently Asked Questions
What is Spark Therapeutics' stock symbol?
Spark Therapeutics trades on the NASDAQ under the ticker symbol "ONCE."
How were Spark Therapeutics' earnings last quarter?
Spark Therapeutics Inc (NASDAQ:ONCE) issued its earnings results on Tuesday, February, 19th. The biotechnology company reported ($1.75) earnings per share for the quarter, missing the Thomson Reuters' consensus estimate of ($0.86) by $0.89. The biotechnology company earned $13.15 million during the quarter, compared to analyst estimates of $26.76 million. Spark Therapeutics had a negative return on equity of 14.94% and a negative net margin of 121.78%. Spark Therapeutics's quarterly revenue was up 47.9% on a year-over-year basis. During the same period in the prior year, the business earned ($1.63) earnings per share. View Spark Therapeutics' Earnings History.
When is Spark Therapeutics' next earnings date?
What price target have analysts set for ONCE?
21 brokerages have issued 1-year target prices for Spark Therapeutics' stock. Their predictions range from $40.00 to $115.00. On average, they anticipate Spark Therapeutics' stock price to reach $80.3240 in the next twelve months. This suggests that the stock has a possible downside of 29.2%. View Analyst Price Targets for Spark Therapeutics.
What is the consensus analysts' recommendation for Spark Therapeutics?
21 Wall Street analysts have issued "buy," "hold," and "sell" ratings for Spark Therapeutics in the last year. There are currently 17 hold ratings and 4 buy ratings for the stock, resulting in a consensus recommendation of "Hold." View Analyst Ratings for Spark Therapeutics.
What are Wall Street analysts saying about Spark Therapeutics stock?
Here are some recent quotes from research analysts about Spark Therapeutics stock:
- 1. William Blair analysts commented, "We see a sound strategic fit with Roche given its recent investment in hemophilia with the launch of Hemlibra (SPK-8011 in hemophilia A, SPK-8016 in hemophilia A patients with inhibitors and royalties from the fidanacogene elaparvovec collaboration with Pfizer), ophthalmology (Luxturna in the United States and royalties from the Luxturna EU launch), and neuroscience (SPK-1001 for CLN2) franchises." (2/26/2019)
- 2. According to Zacks Investment Research, "Spark Therapeutics, Inc. offers gene therapy. The Company's product candidate consist of SPK-RPE65, SPK-CHM, SPK-FIX which are in different clinical phases, for the treatment of additional blinding conditions, hematologic disorders and neurodegenerative diseases. Spark Therapeutics, Inc. is based in Philadelphia, Pennsylvania. " (2/23/2019)
- 3. JPMorgan Chase & Co. analysts commented, "ONCE’s 3Q print encouragingly showed in line Luxturna sales of ~$9M, although a resetting of expectations around the SPK-8011 update at ASH overshadowed launch progress. Given the historical focus on FVIII levels, we aren’t surprised to see disappointment about the news that there will be no biomarker data for the high dose cohort at ASH (there will be clinical outcome data). Indeed, for some time we’ve gotten the sense that at least some investors may wait to see additional SPK-8011 FVIII activity data before re-engaging. That said, today’s update doesn’t fundamentally change the fact that ONCE continues to be a leader in the gene therapy space, with an active early-stage pipeline (2 new programs entering clinic in late- 2018/2019) and an update on SPK-7001 expected by YE18. Maintain Neutral." (11/7/2018)
- 4. Raymond James analysts commented, "We are maintaining our Outperform rating for shares of ONCE. This morning the E.U.’s Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion recommending the approval of LUXTURNA for the treatment of vision loss due to inherited retinal dystrophy (IRD) caused by mutations in the retinal pigment epithelium- specific 65 kDa (RPE65) gene. Along with robust data from the company’s Phase III study that demonstrated safety, efficacy, and durability of response for up to three years, the company awaits a marketing authorization from the European Commission within two months to become the first gene therapy for a genetic disease approved in both the U.S. and E.U. With U.S." (9/21/2018)
Has Spark Therapeutics been receiving favorable news coverage?
Media coverage about ONCE stock has been trending somewhat negative recently, InfoTrie Sentiment reports. The research group rates the sentiment of media coverage by monitoring more than six thousand blog and news sources in real-time. The firm ranks coverage of companies on a scale of negative five to positive five, with scores closest to five being the most favorable. Spark Therapeutics earned a coverage optimism score of -1.1 on InfoTrie's scale. They also assigned media coverage about the biotechnology company a news buzz of 10.0 out of 10, meaning that recent media coverage is extremely likely to have an impact on the stock's share price in the immediate future.
Are investors shorting Spark Therapeutics?
Spark Therapeutics saw a decline in short interest during the month of February. As of February 28th, there was short interest totalling 2,487,319 shares, a decline of 56.9% from the February 15th total of 5,772,685 shares. Based on an average daily volume of 5,623,886 shares, the short-interest ratio is currently 0.4 days. Currently, 7.1% of the company's stock are sold short. View Spark Therapeutics' Current Options Chain.
Who are some of Spark Therapeutics' key competitors?
Some companies that are related to Spark Therapeutics include NOVOZYMES A/S/S (NVZMY), Seattle Genetics (SGEN), Qiagen (QGEN), bluebird bio (BLUE), Neurocrine Biosciences (NBIX), BIO-TECHNE (TECH), argenx (ARGX), Ablynx (ABLYF), China Biologic Products (CBPO), Allogene Therapeutics (ALLO), Repligen (RGEN), Acceleron Pharma (XLRN), Halozyme Therapeutics (HALO), Aerie Pharmaceuticals (AERI) and Regenxbio (RGNX).
What other stocks do shareholders of Spark Therapeutics own?
Who are Spark Therapeutics' key executives?
Spark Therapeutics' management team includes the folowing people:
- Mr. Jeffrey D. Marrazzo, Co-Founder, CEO & Director (Age 40)
- Dr. Katherine A. High, Co-Founder, Pres, Head of R&D and Director (Age 67)
- Mr. Stephen W. Webster, Chief Financial Officer (Age 58)
- Mr. Joseph W. La Barge Esq., J.D., Chief Legal Officer & Sec. (Age 48)
- Mr. Daniel R. Faga, Chief Bus. Officer (Age 39)
When did Spark Therapeutics IPO?
(ONCE) raised $88 million in an initial public offering on Friday, January 30th 2015. The company issued 5,500,000 shares at $15.00-$17.00 per share. J.P. Morgan and Credit Suisse acted as the underwriters for the IPO and Cowen and Company and Sanford C. Bernstein were co-managers.
Who are Spark Therapeutics' major shareholders?
Spark Therapeutics' stock is owned by a number of of institutional and retail investors. Top institutional investors include FMR LLC (10.31%), BlackRock Inc. (8.23%), Partner Fund Management L.P. (5.78%), D. E. Shaw & Co. Inc. (2.69%), Casdin Capital LLC (2.23%) and Great Point Partners LLC (1.67%). Company insiders that own Spark Therapeutics stock include Anand Mehra, Barge Joseph La, Daniel Faga, Hospital Of Philade Children's, Jeffrey D Marrazzo, John Furey, Katherine A High and Stephen W Webster. View Institutional Ownership Trends for Spark Therapeutics.
Which institutional investors are selling Spark Therapeutics stock?
ONCE stock was sold by a variety of institutional investors in the last quarter, including FMR LLC, Rhenman & Partners Asset Management AB, Squarepoint Ops LLC, Lord Abbett & CO. LLC, Elk Creek Partners LLC, WS Management Lllp, TD Asset Management Inc. and Bailard Inc.. Company insiders that have sold Spark Therapeutics company stock in the last year include Hospital Of Philade Children's and John Furey. View Insider Buying and Selling for Spark Therapeutics.
Which institutional investors are buying Spark Therapeutics stock?
ONCE stock was purchased by a variety of institutional investors in the last quarter, including Partner Fund Management L.P., D. E. Shaw & Co. Inc., American Century Companies Inc., Great Point Partners LLC, Norges Bank, Casdin Capital LLC, Dimensional Fund Advisors LP and Dimensional Fund Advisors LP. View Insider Buying and Selling for Spark Therapeutics.
How do I buy shares of Spark Therapeutics?
Shares of ONCE can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Vanguard Brokerage Services, TD Ameritrade, E*TRADE, Scottrade, Fidelity and Charles Schwab.
What is Spark Therapeutics' stock price today?
One share of ONCE stock can currently be purchased for approximately $113.53.
How big of a company is Spark Therapeutics?
Spark Therapeutics has a market capitalization of $4.31 billion and generates $64.72 million in revenue each year. The biotechnology company earns $-78,820,000.00 in net income (profit) each year or ($2.11) on an earnings per share basis. Spark Therapeutics employs 368 workers across the globe.
What is Spark Therapeutics' official website?
How can I contact Spark Therapeutics?
Spark Therapeutics' mailing address is 3737 MARKET STREET SUITE 1300, PHILADELPHIA PA, 19104. The biotechnology company can be reached via phone at 888-772-7560 or via email at [email protected]
MarketBeat Community Rating for Spark Therapeutics (NASDAQ ONCE)
MarketBeat's community ratings are surveys of what our community members think about Spark Therapeutics and other stocks. Vote "Outperform" if you believe ONCE will outperform the S&P 500 over the long term. Vote "Underperform" if you believe ONCE will underperform the S&P 500 over the long term. You may vote once every thirty days.
