Proteostasis Therapeutics, Inc., a clinical stage biopharmaceutical company, discovers and develops novel therapeutics to treat cystic fibrosis and other diseases caused by an imbalance in the proteostasis network. Its lead product candidate is PTI-428, an orally bioavailable cystic fibrosis transmembrane conductance regulator modulator belonging to the amplifier class, which is in Phase II study. The company is also involved in developing PTI-801, a corrector molecule; and PTI-808, a potentiator molecule that have been completed Phase I Study. It has a collaboration agreement with Astellas Pharma Inc. Astellas Pharma, Inc. to research and identify therapies targeting the UPR pathway. The company was formerly known as Proteoguard, Inc. and changed its name to Proteostasis Therapeutics, Inc. in September 2007. Proteostasis Therapeutics, Inc. was founded in 2006 and is headquartered in Cambridge, Massachusetts.
Industry, Sector and Symbol
Industry Pharmaceutical preparations
Sub-IndustryN/A
SectorMedical
Phone617-225-0096
Debt
Price-To-Earnings
Sales & Book Value
Annual Sales$5.34 million
Profitability
Miscellaneous
Employees52
OptionableOptionable
Proteostasis Therapeutics (NASDAQ:PTI) Frequently Asked Questions
What is Proteostasis Therapeutics' stock symbol?
Proteostasis Therapeutics trades on the NASDAQ under the ticker symbol "PTI."
How were Proteostasis Therapeutics' earnings last quarter?
Proteostasis Therapeutics Inc (NASDAQ:PTI) released its quarterly earnings data on Tuesday, November, 14th. The company reported ($0.56) EPS for the quarter, beating analysts' consensus estimates of ($0.72) by $0.16. The company earned $1.55 million during the quarter, compared to analyst estimates of $1.38 million. Proteostasis Therapeutics had a negative net margin of 1,307.84% and a negative return on equity of 104.17%. View Proteostasis Therapeutics' Earnings History.
When is Proteostasis Therapeutics' next earnings date?
What price target have analysts set for PTI?
4 brokers have issued 12-month price objectives for Proteostasis Therapeutics' shares. Their predictions range from $5.00 to $21.00. On average, they anticipate Proteostasis Therapeutics' share price to reach $13.75 in the next year. This suggests a possible upside of 241.2% from the stock's current price. View Analyst Price Targets for Proteostasis Therapeutics.
What is the consensus analysts' recommendation for Proteostasis Therapeutics?
4 Wall Street analysts have issued "buy," "hold," and "sell" ratings for Proteostasis Therapeutics in the last year. There are currently 4 buy ratings for the stock, resulting in a consensus recommendation of "Buy." View Analyst Ratings for Proteostasis Therapeutics.
What are Wall Street analysts saying about Proteostasis Therapeutics stock?
Here are some recent quotes from research analysts about Proteostasis Therapeutics stock:
- 1. According to Zacks Investment Research, "Proteostasis Therapeutics, Inc. is a biopharmaceutical company which focuses on the discovery and development of novel therapeutics to treat diseases caused by an imbalance in the proteostasis network primarily in the United States. Proteostasis Therapeutics, Inc. is based in Cambridge, Massachusetts. " (1/17/2019)
- 2. Cantor Fitzgerald analysts commented, "We reaffirm our OW rating. Proteostasis is developing CFTR modulators for the treatment of cystic fibrosis. The company has a number of ongoing Phase 2 studies evaluating doublet and triplet proprietary drug combinations, with further studies assessing the drugs as add-on therapies to standard of care. Valuation Summary We arrive at our 12-month price target of $21/share by adding the after-tax, risk- adjusted NPV of future cash flows from Proteostasis’ cystic fibrosis programs." (12/17/2018)
Has Proteostasis Therapeutics been receiving favorable news coverage?
Media stories about PTI stock have been trending somewhat negative this week, InfoTrie Sentiment reports. InfoTrie scores the sentiment of press coverage by monitoring more than six thousand blog and news sources in real-time. The firm ranks coverage of public companies on a scale of negative five to five, with scores closest to five being the most favorable. Proteostasis Therapeutics earned a news sentiment score of -1.7 on InfoTrie's scale. They also gave headlines about the company a news buzz of 10.0 out of 10, meaning that recent press coverage is extremely likely to have an effect on the company's share price in the next several days.
Who are some of Proteostasis Therapeutics' key competitors?
Some companies that are related to Proteostasis Therapeutics include Crinetics Pharmaceuticals (CRNX), Kura Oncology (KURA), Karyopharm Therapeutics (KPTI), Lexicon Pharmaceuticals (LXRX), ChemoCentryx (CCXI), Akorn (AKRX), Urogen Pharma (URGN), AMAG Pharmaceuticals (AMAG), Flexion Therapeutics (FLXN), Assembly Biosciences (ASMB), Aurinia Pharmaceuticals (AUPH), Eidos Therapeutics (EIDX), Prothena (PRTA), BioSpecifics Technologies (BSTC) and GlycoMimetics (GLYC).
Who are Proteostasis Therapeutics' key executives?
Proteostasis Therapeutics' management team includes the folowing people:
- Ms. Meenu Chhabra, Pres, CEO & Director (Age 47)
- Dr. Benito Munoz, Chief Scientific Officer (Age 57)
- Dr. Po-Shun Lee, Exec. VP & Chief Medical Officer (Age 50)
- Dr. Marija Zecevic, Chief Operating Officer (Age 45)
- Ms. Janet L. Smart, VP of Intellectual Property & Legal Affairs (Age 62)
When did Proteostasis Therapeutics IPO?
(PTI) raised $51 million in an initial public offering (IPO) on Thursday, February 11th 2016. The company issued 3,900,000 shares at a price of $12.00-$14.00 per share. Leerink Partners and RBC Capital Markets acted as the underwriters for the IPO and Baird and H.C. Wainwright & Co. were co-managers.
Who are Proteostasis Therapeutics' major shareholders?
Proteostasis Therapeutics' stock is owned by many different of retail and institutional investors. Top institutional investors include Jennison Associates LLC (10.17%), Great Point Partners LLC (8.30%), BlackRock Inc. (7.96%), Sectoral Asset Management Inc (4.31%), venBio Select Advisor LLC (3.54%) and Hillhouse Capital Advisors Ltd. (2.36%). Company insiders that own Proteostasis Therapeutics stock include Cormorant Asset Management, Ll, Enterprise Associates 12 New, Fmr Llc, Franklin M Berger, Meenu Chhabra and Po Shun Lee. View Institutional Ownership Trends for Proteostasis Therapeutics.
Which institutional investors are selling Proteostasis Therapeutics stock?
PTI stock was sold by a variety of institutional investors in the last quarter, including RTW Investments LP, Bailard Inc. and Dimensional Fund Advisors LP. Company insiders that have sold Proteostasis Therapeutics company stock in the last year include Meenu Chhabra and Po Shun Lee. View Insider Buying and Selling for Proteostasis Therapeutics.
Which institutional investors are buying Proteostasis Therapeutics stock?
PTI stock was purchased by a variety of institutional investors in the last quarter, including Great Point Partners LLC, Sectoral Asset Management Inc, venBio Select Advisor LLC, BlackRock Inc., Hillhouse Capital Advisors Ltd., Macquarie Group Ltd., Candriam Luxembourg S.C.A. and Bank of New York Mellon Corp. Company insiders that have bought Proteostasis Therapeutics stock in the last two years include Enterprise Associates 12 New, Franklin M Berger and Meenu Chhabra. View Insider Buying and Selling for Proteostasis Therapeutics.
How do I buy shares of Proteostasis Therapeutics?
Shares of PTI can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Vanguard Brokerage Services, TD Ameritrade, E*TRADE, Scottrade, Fidelity and Charles Schwab.
What is Proteostasis Therapeutics' stock price today?
One share of PTI stock can currently be purchased for approximately $4.03.
How big of a company is Proteostasis Therapeutics?
Proteostasis Therapeutics has a market capitalization of $147.90 million and generates $5.34 million in revenue each year. The company earns $-59,430,000.00 in net income (profit) each year or ($2.34) on an earnings per share basis. Proteostasis Therapeutics employs 52 workers across the globe.
What is Proteostasis Therapeutics' official website?
How can I contact Proteostasis Therapeutics?
Proteostasis Therapeutics' mailing address is 80 Guest Street Suite 500, Boston MA, 02135. The company can be reached via phone at 617-225-0096 or via email at [email protected]
MarketBeat Community Rating for Proteostasis Therapeutics (NASDAQ PTI)
MarketBeat's community ratings are surveys of what our community members think about Proteostasis Therapeutics and other stocks. Vote "Outperform" if you believe PTI will outperform the S&P 500 over the long term. Vote "Underperform" if you believe PTI will underperform the S&P 500 over the long term. You may vote once every thirty days.
