Vr Adviser, LLC Top Holdings and 13F Report (2025) About Vr Adviser, LLCInvestment ActivityVr Adviser, LLC has $1.33 billion in total holdings as of June 30, 2025.Vr Adviser, LLC owns shares of 31 different stocks, but just 13 companies or ETFs make up 80% of its holdings.Approximately 10.63% of the portfolio was purchased this quarter.About 9.02% of the portfolio was sold this quarter.This quarter, Vr Adviser, LLC has purchased 37 new stocks and bought additional shares in 4 stocks.Vr Adviser, LLC sold shares of 6 stocks and completely divested from 10 stocks this quarter.Largest Holdings APOGEE THERAPEUTICS INC $368,864,931Ocular Therapeutix $118,435,647METSERA INC $106,706,334Enliven Therapeutics $80,768,200KalVista Pharmaceuticals $76,071,175 Largest New Holdings this Quarter 008064206 - JADE BIOSCIENCES INC $32,171,436 Holding23284F105 - CytomX Therapeutics $31,711,632 HoldingG2545C104 - CRESCENT BIOPHARMA INC. $22,400,125 Holding81734D104 - SEPTERNA INC $5,712,588 Holding Largest Purchases this Quarter Oric Pharmaceuticals 3,414,358 shares (about $34.66M)JADE BIOSCIENCES INC 3,220,364 shares (about $32.17M)CytomX Therapeutics 13,969,882 shares (about $31.71M)CRESCENT BIOPHARMA INC. 1,387,864 shares (about $22.40M)Savara 5,626,624 shares (about $12.83M) Largest Sales this Quarter CIDARA THERAPEUTICS INC 412,430 shares (about $20.09M)Pharvaris 1,065,100 shares (about $18.75M)DIANTHUS THERAPEUTICS INC 744,373 shares (about $13.87M)Cogent Biosciences 929,000 shares (about $6.67M)TENAX THERAPEUTICS INC 109,769 shares (about $632.27K) Sector Allocation Over TimeMap of 500 Largest Holdings ofVr Adviser, LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorAPOGEE THERAPEUTICS INC$368,864,9310.0%8,493,32127.6%COMOCULOcular Therapeutix$118,435,6470.0%12,762,4628.9%MedicalMETSERA INC$106,706,3340.0%3,750,6628.0%COMELVNEnliven Therapeutics$80,768,2000.0%4,026,3316.1%MedicalKALVKalVista Pharmaceuticals$76,071,175$282,625 ▲0.4%6,728,9855.7%MedicalORICOric Pharmaceuticals$66,958,383$34,655,734 ▲107.3%6,596,8855.0%MedicalVRDNViridian Therapeutics$54,280,2720.0%3,882,7094.1%MedicalORUKA THERAPEUTICS INC$46,503,8780.0%4,148,4283.5%COMSPYRE THERAPEUTICS INC$40,201,1570.0%2,685,4483.0%COM NEWPHVSPharvaris$36,038,112$18,745,760 ▼-34.2%2,047,6202.7%MedicalCOGTCogent Biosciences$34,143,851$6,670,220 ▼-16.3%4,755,4112.6%MedicalJADE BIOSCIENCES INC$32,171,436$32,171,436 ▲New Holding3,220,3642.4%COM NEWCTMXCytomX Therapeutics$31,711,632$31,711,632 ▲New Holding13,969,8822.4%MedicalCIDARA THERAPEUTICS INC$31,129,976$20,089,465 ▼-39.2%639,0882.3%COM NEWUPSTREAM BIO INC$25,202,6030.0%2,295,3191.9%COMERASErasca$22,678,495$2,083,901 ▲10.1%17,857,0831.7%MedicalCRESCENT BIOPHARMA INC.$22,400,125$22,400,125 ▲New Holding1,387,8641.7%COMDYNE THERAPEUTICS INC$20,695,6520.0%2,173,9131.6%COMSVRASavara$20,256,120$12,828,703 ▲172.7%8,884,2631.5%MedicalDIANTHUS THERAPEUTICS INC$18,630,000$13,867,669 ▼-42.7%1,000,0001.4%COMENGENE HOLDINGS INC$18,368,9470.0%5,046,4141.4%COMATXSAstria Therapeutics$13,171,3850.0%2,457,3481.0%MedicalCGEMCullinan Therapeutics$10,391,1360.0%1,379,9650.8%MedicalABIVAX SA$10,295,2170.0%1,345,7800.8%SPONSORED ADSPERCEPTIVE CAP SOLUTIONS COR$7,965,0000.0%750,0000.6%CL A ORD SHSSEPTERNA INC$5,712,588$5,712,588 ▲New Holding540,4530.4%COMSURROZEN INC$5,658,4030.0%632,9310.4%COM NEWZURAZura Bio$4,862,777$411,548 ▼-7.8%4,631,2160.4%MedicalARTIVA BIOTHERAPEUTICS INC$2,430,4490.0%1,609,5690.2%COMCASICASI Pharmaceuticals$1,164,9660.0%987,2590.1%MedicalTENAX THERAPEUTICS INC$567,729$632,270 ▼-52.7%98,5640.0%COM NEWPRAXIS PRECISION MEDICINES I$0$37,490,732 ▼-100.0%00.0%COM NEWSLDBSolid Biosciences$0$9,181,180 ▼-100.0%00.0%MedicalTRVITrevi Therapeutics$0$3,871,533 ▼-100.0%00.0%MedicalAPLTApplied Therapeutics$0$2,722,053 ▼-100.0%00.0%MedicalFDMT4D Molecular Therapeutics$0$2,188,648 ▼-100.0%00.0%MedicalMRSNMersana Therapeutics$0$1,230,283 ▼-100.0%00.0%MedicalIPSCCentury Therapeutics$0$1,189,081 ▼-100.0%00.0%MedicalTNYATenaya Therapeutics$0$886,822 ▼-100.0%00.0%MedicalGLYCGlycoMimetics$0$630,000 ▼-100.0%00.0%MedicalINSTIL BIO INC$0$575,953 ▼-100.0%00.0%COM NEWShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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