NASDAQ:AGLE - Aeglea Bio Therapeutics Stock Price, News, & Analysis Sign in or create an account to add this stock to your watchlist. Get Started $8.25 +0.05 (+0.61 %) (As of 03/20/2019 06:13 AM ET)Previous Close$8.20Today's Range$8.05 - $8.3052-Week Range$6.31 - $12.00Volume103,175 shsAverage Volume159,411 shsMarket Capitalization$237.77 millionP/E Ratio-3.87Dividend YieldN/ABeta1.07 ProfileDiscussionAnalyst RatingsChartEarningsFinancialsInsider TradesInstitutional OwnershipHeadlinesOptions ChainSEC FilingsSocial Media Share on FacebookShare on TwitterShare on LinkedInShare on RedditShare on StocktwitsPrint this articleShare by Email Aeglea BioTherapeutics, Inc., a clinical-stage biotechnology company, designs and develops human enzyme therapeutics for the treatment of patients with rare genetic diseases and cancer. The company's lead product candidate includes pegzilarginase, a recombinant human Arginase 1 enzyme, which is in early clinical development stage for the treatment of Arginase 1 deficiency, an autosomal recessive metabolic disease caused by a marked decrease in the activity of the native arginase 1 enzyme; and for treating Arginine dependent cancers. Its preclinical pipeline products comprise AEB3103, an engineered human enzyme that targets the degradation of the amino acid cysteine/cysteine; and AEB2109, an engineered human enzyme that targets the degradation of the amino acid methionine, as well as AEB4104, an engineered human enzyme that targets the reduction of elevated levels of the amino acid homocysteine. Aeglea BioTherapeutics, Inc. has a clinical collaboration agreement with Merck to evaluate the combination of pegzilarginase with Merck's anti-PD1 therapy, pembrolizumab, for the treatment of patients with small cell lung cancer. The company was formerly known as Aeglea BioTherapeutics Holdings, LLC and changed its name to Aeglea BioTherapeutics, Inc. in March 2015. Aeglea BioTherapeutics, Inc. was founded in 2013 and is headquartered in Austin, Texas. Receive AGLE News and Ratings via Email Sign-up to receive the latest news and ratings for AGLE and its competitors with MarketBeat's FREE daily newsletter. Industry, Sector and Symbol Stock Exchange NASDAQ Industry Pharmaceutical preparations Sub-IndustryN/A SectorMedical Current SymbolNASDAQ:AGLE Previous Symbol CUSIPN/A CIK1636282 Webwww.aegleabio.com Phone512-942-2935Debt Debt-to-Equity RatioN/A Current Ratio7.49 Quick Ratio7.49Price-To-Earnings Trailing P/E Ratio-3.87 Forward P/E Ratio-4.85 P/E GrowthN/A Sales & Book Value Annual Sales$3.89 million Price / Sales61.12 Cash FlowN/A Price / Cash FlowN/A Book Value$2.81 per share Price / Book2.94Profitability EPS (Most Recent Fiscal Year)($2.13) Net Income$-44,350,000.00 Net Margins-480.92% Return on Equity-71.39% Return on Assets-63.70%Miscellaneous EmployeesN/A Outstanding Shares28,820,000Market Cap$237.77 million Next Earnings Date5/14/2019 (Estimated) OptionableOptionable Aeglea Bio Therapeutics (NASDAQ:AGLE) Frequently Asked Questions What is Aeglea Bio Therapeutics' stock symbol? Aeglea Bio Therapeutics trades on the NASDAQ under the ticker symbol "AGLE." How were Aeglea Bio Therapeutics' earnings last quarter? Aeglea Bio Therapeutics Inc (NASDAQ:AGLE) released its quarterly earnings results on Thursday, March, 7th. The biotechnology company reported ($0.64) earnings per share (EPS) for the quarter, missing analysts' consensus estimates of ($0.37) by $0.27. Aeglea Bio Therapeutics had a negative net margin of 480.92% and a negative return on equity of 71.39%. View Aeglea Bio Therapeutics' Earnings History. When is Aeglea Bio Therapeutics' next earnings date? Aeglea Bio Therapeutics is scheduled to release their next quarterly earnings announcement on Tuesday, May 14th 2019. View Earnings Estimates for Aeglea Bio Therapeutics. What price target have analysts set for AGLE? 4 brokerages have issued 1 year price targets for Aeglea Bio Therapeutics' stock. Their forecasts range from $20.00 to $37.00. On average, they anticipate Aeglea Bio Therapeutics' stock price to reach $26.00 in the next twelve months. This suggests a possible upside of 215.2% from the stock's current price. View Analyst Price Targets for Aeglea Bio Therapeutics. What is the consensus analysts' recommendation for Aeglea Bio Therapeutics? 4 Wall Street analysts have issued "buy," "hold," and "sell" ratings for Aeglea Bio Therapeutics in the last year. There are currently 1 hold rating and 3 buy ratings for the stock, resulting in a consensus recommendation of "Buy." View Analyst Ratings for Aeglea Bio Therapeutics. Has Aeglea Bio Therapeutics been receiving favorable news coverage? News articles about AGLE stock have been trending positive this week, InfoTrie Sentiment reports. The research group rates the sentiment of media coverage by reviewing more than six thousand blog and news sources. The firm ranks coverage of companies on a scale of negative five to positive five, with scores nearest to five being the most favorable. Aeglea Bio Therapeutics earned a coverage optimism score of 2.1 on InfoTrie's scale. They also assigned news stories about the biotechnology company a news buzz of 6.0 out of 10, meaning that recent media coverage is somewhat likely to have an impact on the stock's share price in the next several days. Are investors shorting Aeglea Bio Therapeutics? Aeglea Bio Therapeutics saw a decrease in short interest during the month of February. As of February 28th, there was short interest totalling 471,970 shares, a decrease of 45.4% from the February 15th total of 865,047 shares. Based on an average daily trading volume, of 134,261 shares, the days-to-cover ratio is currently 3.5 days. Currently, 2.1% of the company's stock are short sold. View Aeglea Bio Therapeutics' Current Options Chain. Who are some of Aeglea Bio Therapeutics' key competitors? Some companies that are related to Aeglea Bio Therapeutics include Alder Biopharmaceuticals (ALDR), MacroGenics (MGNX), Dicerna Pharmaceuticals (DRNA), Principia Biopharma (PRNB), Advanz Pharma (CXRXF), Radius Health (RDUS), Athenex (ATNX), Omeros (OMER), Lexicon Pharmaceuticals (LXRX), CymaBay Therapeutics (CBAY), Y-mAbs Therapeutics (YMAB), Cara Therapeutics (CARA), ANI Pharmaceuticals (ANIP), Eidos Therapeutics (EIDX) and Rocket Pharmaceuticals (RCKT). What other stocks do shareholders of Aeglea Bio Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some companies that other Aeglea Bio Therapeutics investors own include ACADIA Pharmaceuticals (ACAD), Exelixis (EXEL), Vericel (VCEL), Fate Therapeutics (FATE), Bellicum Pharmaceuticals (BLCM), Puma Biotechnology (PBYI), Array Biopharma (ARRY), AbbVie (ABBV), Abeona Therapeutics (ABEO) and GW Pharmaceuticals PLC- (GWPH). Who are Aeglea Bio Therapeutics' key executives? Aeglea Bio Therapeutics' management team includes the folowing people: Dr. Anthony G. Quinn M.B Ch.B., Ph.D., FRCP, Pres, CEO & Director (Age 57)Mr. Charles N. York II, CFO & VP (Age 42)Dr. James E. Wooldridge M.D., Chief Medical Officer (Age 53)Dr. Leslie Sloan Ph.D., Sr. VP of OperationsMr. Eugene Sackett, VP of HR When did Aeglea Bio Therapeutics IPO? (AGLE) raised $60 million in an initial public offering (IPO) on Thursday, April 7th 2016. The company issued 3,500,000 shares at $16.00-$18.00 per share. UBS Investment Bank, BMO Capital Markets and Wells Fargo Securities served as the underwriters for the IPO and Needham & Company was co-manager. Who are Aeglea Bio Therapeutics' major shareholders? Aeglea Bio Therapeutics' stock is owned by many different of institutional and retail investors. Top institutional investors include Jennison Associates LLC (5.64%), BlackRock Inc. (5.44%), Aisling Capital Management LP (3.63%), Sphera Funds Management LTD. (2.50%), Comprehensive Portfolio Management LLC (1.21%) and Dimensional Fund Advisors LP (1.19%). Company insiders that own Aeglea Bio Therapeutics stock include Aaron Schuchart, Anthony G Quinn, Bioventures Ltd Novartis and Charles N York II. View Institutional Ownership Trends for Aeglea Bio Therapeutics. Which major investors are selling Aeglea Bio Therapeutics stock? AGLE stock was sold by a variety of institutional investors in the last quarter, including Jennison Associates LLC, Sphera Funds Management LTD., Deltec Asset Management LLC, Squarepoint Ops LLC and Bank of Montreal Can. Company insiders that have sold Aeglea Bio Therapeutics company stock in the last year include Aaron Schuchart and Bioventures Ltd Novartis. View Insider Buying and Selling for Aeglea Bio Therapeutics. Which major investors are buying Aeglea Bio Therapeutics stock? AGLE stock was bought by a variety of institutional investors in the last quarter, including Aisling Capital Management LP, Comprehensive Portfolio Management LLC, BlackRock Inc., Dimensional Fund Advisors LP, Dimensional Fund Advisors LP, Fosun International Ltd, Algert Global LLC and Millennium Management LLC. Company insiders that have bought Aeglea Bio Therapeutics stock in the last two years include Anthony G Quinn and Charles N York II. View Insider Buying and Selling for Aeglea Bio Therapeutics. How do I buy shares of Aeglea Bio Therapeutics? Shares of AGLE can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Vanguard Brokerage Services, TD Ameritrade, E*TRADE, Scottrade, Fidelity and Charles Schwab. What is Aeglea Bio Therapeutics' stock price today? One share of AGLE stock can currently be purchased for approximately $8.25. How big of a company is Aeglea Bio Therapeutics? Aeglea Bio Therapeutics has a market capitalization of $237.77 million and generates $3.89 million in revenue each year. The biotechnology company earns $-44,350,000.00 in net income (profit) each year or ($2.13) on an earnings per share basis. What is Aeglea Bio Therapeutics' official website? The official website for Aeglea Bio Therapeutics is http://www.aegleabio.com. How can I contact Aeglea Bio Therapeutics? Aeglea Bio Therapeutics' mailing address is 901 SOUTH MOPAC EXPRESSWAY BARTON OAKS PLAZA ONE SUITE 250, AUSTIN TX, 78746. The biotechnology company can be reached via phone at 512-942-2935 or via email at [email protected] MarketBeat Community Rating for Aeglea Bio Therapeutics (NASDAQ AGLE)Community Ranking: 2.8 out of 5 ( )Outperform Votes: 165 (Vote Outperform)Underperform Votes: 131 (Vote Underperform)Total Votes: 296MarketBeat's community ratings are surveys of what our community members think about Aeglea Bio Therapeutics and other stocks. Vote "Outperform" if you believe AGLE will outperform the S&P 500 over the long term. Vote "Underperform" if you believe AGLE will underperform the S&P 500 over the long term. You may vote once every thirty days. This page was last updated on 3/20/2019 by MarketBeat.com StaffFeatured Article: Is a Roth IRA right for you?