NASDAQ:AGLE - Aeglea Bio Therapeutics Stock Price, News, & Analysis Sign in or create an account to add this stock to your watchlist. Get Started $7.50 -0.19 (-2.47 %) (As of 12/14/2018 04:00 PM ET)Previous Close$7.50Today's Range$7.40 - $7.8252-Week Range$4.86 - $12.00Volume72,294 shsAverage Volume84,270 shsMarket Capitalization$184.27 millionP/E Ratio-4.17Dividend YieldN/ABeta0.62 ProfileDiscussionAnalyst RatingsChartEarningsFinancialsInsider TradesInstitutional OwnershipHeadlinesOptions ChainSEC FilingsSocial Media Share on FacebookShare on TwitterShare on LinkedInShare on RedditShare on StocktwitsPrint this articleShare by Email Aeglea BioTherapeutics, Inc., a clinical-stage biotechnology company, designs and develops human enzyme therapeutics for the treatment of patients with rare genetic diseases and cancer. The company's lead product candidate includes pegzilarginase, a recombinant human Arginase 1 enzyme, which is in early clinical development stage for the treatment of Arginase 1 deficiency, an autosomal recessive metabolic disease caused by a marked decrease in the activity of the native arginase 1 enzyme; and for treating Arginine dependent cancers. Its preclinical pipeline products comprise AEB3103, an engineered human enzyme that targets the degradation of the amino acid cysteine/cysteine; and AEB2109, an engineered human enzyme that targets the degradation of the amino acid methionine, as well as AEB4104, an engineered human enzyme that targets the reduction of elevated levels of the amino acid homocysteine. Aeglea BioTherapeutics, Inc. has a clinical collaboration agreement with Merck to evaluate the combination of pegzilarginase with Merck's anti-PD1 therapy, pembrolizumab, for the treatment of patients with small cell lung cancer. The company was formerly known as Aeglea BioTherapeutics Holdings, LLC and changed its name to Aeglea BioTherapeutics, Inc. in March 2015. Aeglea BioTherapeutics, Inc. was founded in 2013 and is headquartered in Austin, Texas. Receive AGLE News and Ratings via Email Sign-up to receive the latest news and ratings for AGLE and its competitors with MarketBeat's FREE daily newsletter. Industry, Sector and Symbol Stock Exchange NASDAQ Industry Pharmaceutical preparations Sub-IndustryN/A SectorMedical Current SymbolNASDAQ:AGLE Previous Symbol CUSIPN/A Webwww.aegleabio.com Phone512-942-2935 Debt Debt-to-Equity RatioN/A Current Ratio9.37 Quick Ratio9.37 Price-To-Earnings Trailing P/E Ratio-4.17 Forward P/E Ratio-4.03 P/E GrowthN/A Sales & Book Value Annual Sales$5.20 million Price / Sales34.56 Cash FlowN/A Price / Cash FlowN/A Book Value$3.02 per share Price / Book2.48 Profitability EPS (Most Recent Fiscal Year)($1.80) Net Income$-27,230,000.00 Net Margins-480.92% Return on Equity-62.12% Return on Assets-55.96% Miscellaneous Employees43 Outstanding Shares23,960,000Market Cap$184.27 million OptionableOptionable Aeglea Bio Therapeutics (NASDAQ:AGLE) Frequently Asked Questions What is Aeglea Bio Therapeutics' stock symbol? Aeglea Bio Therapeutics trades on the NASDAQ under the ticker symbol "AGLE." How were Aeglea Bio Therapeutics' earnings last quarter? Aeglea Bio Therapeutics Inc (NASDAQ:AGLE) issued its quarterly earnings data on Thursday, November, 8th. The biotechnology company reported ($0.54) EPS for the quarter, missing the Thomson Reuters' consensus estimate of ($0.44) by $0.10. Aeglea Bio Therapeutics had a negative return on equity of 62.12% and a negative net margin of 480.92%. View Aeglea Bio Therapeutics' Earnings History. When is Aeglea Bio Therapeutics' next earnings date? Aeglea Bio Therapeutics is scheduled to release their next quarterly earnings announcement on Tuesday, March 12th 2019. View Earnings Estimates for Aeglea Bio Therapeutics. What price target have analysts set for AGLE? 4 brokerages have issued twelve-month price objectives for Aeglea Bio Therapeutics' shares. Their predictions range from $20.00 to $37.00. On average, they anticipate Aeglea Bio Therapeutics' share price to reach $26.00 in the next year. This suggests a possible upside of 246.7% from the stock's current price. View Analyst Price Targets for Aeglea Bio Therapeutics. What is the consensus analysts' recommendation for Aeglea Bio Therapeutics? 4 Wall Street analysts have issued "buy," "hold," and "sell" ratings for Aeglea Bio Therapeutics in the last year. There are currently 1 hold rating and 3 buy ratings for the stock, resulting in a consensus recommendation of "Buy." View Analyst Ratings for Aeglea Bio Therapeutics. Has Aeglea Bio Therapeutics been receiving favorable news coverage? News headlines about AGLE stock have been trending somewhat positive recently, InfoTrie reports. The research group rates the sentiment of news coverage by monitoring more than six thousand blog and news sources in real time. The firm ranks coverage of publicly-traded companies on a scale of negative five to positive five, with scores nearest to five being the most favorable. Aeglea Bio Therapeutics earned a news sentiment score of 1.2 on InfoTrie's scale. They also assigned headlines about the biotechnology company a news buzz of 6.0 out of 10, indicating that recent news coverage is somewhat likely to have an impact on the company's share price in the near future. Who are some of Aeglea Bio Therapeutics' key competitors? Some companies that are related to Aeglea Bio Therapeutics include Radius Health (RDUS), Aptinyx (APTX), Principia Biopharma (PRNB), Forty Seven (FTSV), ProQR Therapeutics (PRQR), CytomX Therapeutics (CTMX), Viking Therapeutics (VKTX), Dynavax Technologies (DVAX), Omeros (OMER), ANI Pharmaceuticals (ANIP), Inflarx (IFRX), Rocket Pharmaceuticals (RCKT), Eagle Pharmaceuticals (EGRX), Kezar Life Sciences (KZR) and MacroGenics (MGNX). Who are Aeglea Bio Therapeutics' key executives? Aeglea Bio Therapeutics' management team includes the folowing people: Dr. Anthony G. Quinn M.B Ch.B., Ph.D., FRCP, Pres, CEO & Director (Age 56)Mr. Charles N. York II, CFO & VP (Age 41)Dr. Leslie Sloan Ph.D., Sr. VP of OperationsMs. Tammy Deal, VP of HRDr. James E. Wooldridge M.D., Chief Medical Officer (Age 52) When did Aeglea Bio Therapeutics IPO? (AGLE) raised $60 million in an IPO on Thursday, April 7th 2016. The company issued 3,500,000 shares at a price of $16.00-$18.00 per share. UBS Investment Bank, BMO Capital Markets and Wells Fargo Securities acted as the underwriters for the IPO and Needham & Company was co-manager. Who are Aeglea Bio Therapeutics' major shareholders? Aeglea Bio Therapeutics' stock is owned by a number of of retail and institutional investors. Top institutional investors include Jennison Associates LLC (6.94%), BlackRock Inc. (4.66%), Vanguard Group Inc. (3.14%), Vanguard Group Inc (3.14%), Sphera Funds Management LTD. (2.73%) and Renaissance Technologies LLC (1.95%). Company insiders that own Aeglea Bio Therapeutics stock include Aaron Schuchart, Anthony G Quinn, Bioventures Ltd Novartis, Charles N York II and Orbimed Advisors Llc. View Institutional Ownership Trends for Aeglea Bio Therapeutics. Which institutional investors are selling Aeglea Bio Therapeutics stock? AGLE stock was sold by a variety of institutional investors in the last quarter, including JPMorgan Chase & Co., Deltec Asset Management LLC, Renaissance Technologies LLC, Wells Fargo & Company MN, Man Group plc, Acadian Asset Management LLC and TIAA CREF Investment Management LLC. Company insiders that have sold Aeglea Bio Therapeutics company stock in the last year include Aaron Schuchart and Bioventures Ltd Novartis. View Insider Buying and Selling for Aeglea Bio Therapeutics. Which institutional investors are buying Aeglea Bio Therapeutics stock? AGLE stock was acquired by a variety of institutional investors in the last quarter, including Point72 Asset Management L.P., BlackRock Inc., Sphera Funds Management LTD., Dimensional Fund Advisors LP, Vanguard Group Inc, Vanguard Group Inc., AQR Capital Management LLC and Jennison Associates LLC. Company insiders that have bought Aeglea Bio Therapeutics stock in the last two years include Anthony G Quinn, Charles N York II and Orbimed Advisors Llc. View Insider Buying and Selling for Aeglea Bio Therapeutics. How do I buy shares of Aeglea Bio Therapeutics? Shares of AGLE can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Vanguard Brokerage Services, TD Ameritrade, E*TRADE, Scottrade, Fidelity and Charles Schwab. What is Aeglea Bio Therapeutics' stock price today? One share of AGLE stock can currently be purchased for approximately $7.50. How big of a company is Aeglea Bio Therapeutics? Aeglea Bio Therapeutics has a market capitalization of $184.27 million and generates $5.20 million in revenue each year. The biotechnology company earns $-27,230,000.00 in net income (profit) each year or ($1.80) on an earnings per share basis. Aeglea Bio Therapeutics employs 43 workers across the globe. What is Aeglea Bio Therapeutics' official website? The official website for Aeglea Bio Therapeutics is http://www.aegleabio.com. How can I contact Aeglea Bio Therapeutics? Aeglea Bio Therapeutics' mailing address is 901 SOUTH MOPAC EXPRESSWAY BARTON OAKS PLAZA ONE SUITE 250, AUSTIN TX, 78746. The biotechnology company can be reached via phone at 512-942-2935 or via email at [email protected] MarketBeat Community Rating for Aeglea Bio Therapeutics (NASDAQ AGLE)Community Ranking: 2.8 out of 5 ( )Outperform Votes: 149 (Vote Outperform)Underperform Votes: 116 (Vote Underperform)Total Votes: 265MarketBeat's community ratings are surveys of what our community members think about Aeglea Bio Therapeutics and other stocks. Vote "Outperform" if you believe AGLE will outperform the S&P 500 over the long term. Vote "Underperform" if you believe AGLE will underperform the S&P 500 over the long term. You may vote once every thirty days. This page was last updated on 12/15/2018 by MarketBeat.com StaffFeatured Article: What is Net Asset Value (NAV)?