This company has been marked as potentially delisted and may not be actively trading. NASDAQ:AGLE Aeglea BioTherapeutics (AGLE) Stock Price, News & Analysis Add Compare Share Share Stock Analysis Stock AnalysisBuy This Stock About Aeglea BioTherapeutics Stock (NASDAQ:AGLE) 30 days 90 days 365 days Advanced Chart Get Aeglea BioTherapeutics alerts:Sign Up Key Stats Today's Range N/A50-Day Range$9.47▼$13.7652-Week Range N/AVolume43,300 shsAverage Volume95,409 shsMarket Capitalization$48.64 millionP/E RatioN/ADividend YieldN/APrice TargetN/AConsensus RatingN/A Company OverviewAeglea BioTherapeutics, Inc., a clinical-stage biotechnology company, designs and develops human enzyme therapeutics for the treatment of rare metabolic diseases. The company's therapeutic candidates include pegtarviliase, a polyethylene glycol modified, which is in Phase I/II clinical trial for the treatment of patient with homocystinuria; and pegzilarginase, a recombinant human Arginase 1 that is in Phase III PEACE trial to evaluate the safety and efficacy for the treatment of Arginase 1 deficiency. In addition, its preclinical pipeline includes AGLE-325 for the treatment of cystinuria, as well as other research programs. The company was formerly known as Aeglea BioTherapeutics Holdings, LLC and changed its name to Aeglea BioTherapeutics, Inc. in March 2015. Aeglea BioTherapeutics, Inc. was founded in 2013 and is headquartered in Austin, Texas.Read More… Receive AGLE Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Aeglea BioTherapeutics and its competitors with MarketBeat's FREE daily newsletter. Email Address AGLE Stock News HeadlinesSpyre Therapeutics Advances IBD Treatment PipelineNovember 9, 2024 | markets.businessinsider.comNorthwest Biotherapeutics Stock (OTC:NWBO), Analyst Ratings, Price Targets, PredictionsFebruary 21, 2024 | benzinga.comThe IRS Loophole That Lets You Own Gold Tax-FreeWhat if I told you there's a legal way to own real physical gold and silver—and keep your gains tax-free? No gimmicks. No shady tricks. Just a powerful IRS-approved loophole that most Americans have never heard of. It's called a Self-Directed Gold IRA, and it's quietly becoming the go-to wealth protection strategy for people who see the writing on the wall. When you take the next step, you could qualify for up to $10,000 in FREE GOLD & SILVER with your purchase of a qualified account.June 20, 2025 | Advantage Gold (Ad)Bridge Biotherapeutics Inc.January 30, 2024 | wsj.comSpyre Therapeutics Announces $180 Million Private PlacementDecember 7, 2023 | finance.yahoo.comAeglea Biotherapeutics announces name change to Spyre TherapeuticsNovember 27, 2023 | msn.comAeglea BioTherapeutics Changes Name To Spyre Therapeutics; To Begin Trading Under Symbol SYRENovember 27, 2023 | markets.businessinsider.comAeglea BioTherapeutics Announces Name Change to Spyre Therapeutics, Appoints CEO and Additional Directors, and Expands Leadership Team to Develop Next-Generation Therapeutic Combinations for the Treatment of IBDNovember 27, 2023 | finance.yahoo.comSee More Headlines AGLE Stock Analysis - Frequently Asked Questions How were Aeglea BioTherapeutics' earnings last quarter? Aeglea BioTherapeutics, Inc. (NASDAQ:AGLE) released its earnings results on Thursday, November, 4th. The biotechnology company reported ($7.75) earnings per share (EPS) for the quarter, missing analysts' consensus estimates of ($7.00) by $0.75. The biotechnology company earned $1.40 million during the quarter, compared to analyst estimates of $1.38 million. Aeglea BioTherapeutics had a negative net margin of 22,195.36% and a negative trailing twelve-month return on equity of 132.05%. When did Aeglea BioTherapeutics' stock split? Aeglea BioTherapeutics's stock reverse split on Friday, September 8th 2023. The 1-25 reverse split was announced on Thursday, September 7th 2023. The number of shares owned by shareholders was adjusted after the closing bell on Thursday, September 7th 2023. An investor that had 100 shares of stock prior to the reverse split would have 4 shares after the split. When did Aeglea BioTherapeutics IPO? Aeglea BioTherapeutics (AGLE) raised $60 million in an initial public offering on Thursday, April 7th 2016. The company issued 3,500,000 shares at a price of $16.00-$18.00 per share. UBS Investment Bank, BMO Capital Markets and Wells Fargo Securities served as the underwriters for the IPO and Needham & Company was co-manager. What other stocks do shareholders of Aeglea BioTherapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Aeglea BioTherapeutics investors own include Bristol Myers Squibb (BMY), Athenex (ATNX), Dynavax Technologies (DVAX), Enterprise Products Partners (EPD), Amarin (AMRN), Axsome Therapeutics (AXSM) and AbbVie (ABBV). Company Calendar Last Earnings11/04/2021Today6/20/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry Pharmaceutical preparations Sub-IndustryN/A Current SymbolNASDAQ:AGLE CIK1636282 Webwww.aegleabio.com Phone(512) 942-2935Fax512-872-5121Employees69Year FoundedN/AProfitability EPS (Most Recent Fiscal Year)($75.59) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$83.82 million Net Margins-22,195.36% Pretax Margin-27,931.12% Return on Equity-132.05% Return on Assets-146.87% Debt Debt-to-Equity RatioN/A Current Ratio4.59 Quick Ratio4.59 Sales & Book Value Annual Sales$2.33 million Price / Sales0.00 Cash FlowN/A Price / Cash FlowN/A Book Value($60.61) per share Price / BookN/AMiscellaneous Outstanding Shares4,050,000Free Float3,782,000Market Cap$48.64 million OptionableOptionable Beta2.57 Social Links 10 Stocks Set to Soar in Summer 2025Enter your email address and we'll send you MarketBeat's list of ten stocks that are set to soar in Summer 2025, despite the threat of tariffs and other economic uncertainty. These ten stocks are incredibly resilient and are likely to thrive in any economic environment.Get This Free Report This page (NASDAQ:AGLE) was last updated on 6/20/2025 by MarketBeat.com Staff From Our PartnersPresidential Bombshell: $150T Resource to Be Released as soon as this Summer?Something extraordinary is happening in Washington. For the first time in over a century, a sitting Preside...Paradigm Press | SponsoredTrump’s treachery Trump’s Final Reset Inside the shocking plot to re-engineer America’s financial system…and why you need to ...Porter & Company | Sponsored379 passengers walked away from thisWhy Elon Musk Just Invested $51 Million Into Brand New “Miracle Metal” Developed by MIT ScientistsTrue Market Insiders | SponsoredThe Robotics Revolution has arrived … and one $7 stock could take off as a result.Something big is brewing in Washington. 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