This company has been marked as potentially delisted and may not be actively trading. NASDAQ:AGLE Aeglea BioTherapeutics (AGLE) Stock Price, News & Analysis Add Compare Share Share Stock Analysis Stock AnalysisBuy This Stock About Aeglea BioTherapeutics Stock (NASDAQ:AGLE) 30 days 90 days 365 days Advanced Chart Get Aeglea BioTherapeutics alerts:Sign Up Key Stats Today's Range N/A50-Day Range$9.47▼$13.7652-Week Range N/AVolume43,300 shsAverage Volume95,409 shsMarket Capitalization$48.64 millionP/E RatioN/ADividend YieldN/APrice TargetN/AConsensus RatingN/A Company OverviewAeglea BioTherapeutics, Inc., a clinical-stage biotechnology company, designs and develops human enzyme therapeutics for the treatment of rare metabolic diseases. The company's therapeutic candidates include pegtarviliase, a polyethylene glycol modified, which is in Phase I/II clinical trial for the treatment of patient with homocystinuria; and pegzilarginase, a recombinant human Arginase 1 that is in Phase III PEACE trial to evaluate the safety and efficacy for the treatment of Arginase 1 deficiency. In addition, its preclinical pipeline includes AGLE-325 for the treatment of cystinuria, as well as other research programs. The company was formerly known as Aeglea BioTherapeutics Holdings, LLC and changed its name to Aeglea BioTherapeutics, Inc. in March 2015. Aeglea BioTherapeutics, Inc. was founded in 2013 and is headquartered in Austin, Texas.Read More… Receive AGLE Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Aeglea BioTherapeutics and its competitors with MarketBeat's FREE daily newsletter. Email Address AGLE Stock News HeadlinesSpyre Therapeutics Advances IBD Treatment PipelineNovember 9, 2024 | markets.businessinsider.comNorthwest Biotherapeutics Stock (OTC:NWBO), Analyst Ratings, Price Targets, PredictionsFebruary 21, 2024 | benzinga.comThis robot is coming to 65 million Americans … this year.Robots are the hottest thing going in tech right now. And they just had a coming-out party in Las Vegas. Everywhere you turned at the Consumer Electronics Show, a robot was there to greet you.May 10, 2025 | Weiss Ratings (Ad)Bridge Biotherapeutics Inc.January 30, 2024 | wsj.comSpyre Therapeutics Announces $180 Million Private PlacementDecember 7, 2023 | finance.yahoo.comAeglea Biotherapeutics announces name change to Spyre TherapeuticsNovember 27, 2023 | msn.comAeglea BioTherapeutics Changes Name To Spyre Therapeutics; To Begin Trading Under Symbol SYRENovember 27, 2023 | markets.businessinsider.comAeglea BioTherapeutics Announces Name Change to Spyre Therapeutics, Appoints CEO and Additional Directors, and Expands Leadership Team to Develop Next-Generation Therapeutic Combinations for the Treatment of IBDNovember 27, 2023 | finance.yahoo.comSee More Headlines AGLE Stock Analysis - Frequently Asked Questions How were Aeglea BioTherapeutics' earnings last quarter? Aeglea BioTherapeutics, Inc. (NASDAQ:AGLE) announced its quarterly earnings data on Thursday, November, 4th. The biotechnology company reported ($7.75) EPS for the quarter, missing analysts' consensus estimates of ($7.00) by $0.75. The biotechnology company earned $1.40 million during the quarter, compared to the consensus estimate of $1.38 million. Aeglea BioTherapeutics had a negative net margin of 22,195.36% and a negative trailing twelve-month return on equity of 132.05%. When did Aeglea BioTherapeutics' stock split? Aeglea BioTherapeutics's stock reverse split on the morning of Friday, September 8th 2023. The 1-25 reverse split was announced on Thursday, September 7th 2023. The number of shares owned by shareholders was adjusted after the closing bell on Thursday, September 7th 2023. An investor that had 100 shares of stock prior to the reverse split would have 4 shares after the split. When did Aeglea BioTherapeutics IPO? Aeglea BioTherapeutics (AGLE) raised $60 million in an initial public offering on Thursday, April 7th 2016. The company issued 3,500,000 shares at a price of $16.00-$18.00 per share. UBS Investment Bank, BMO Capital Markets and Wells Fargo Securities acted as the underwriters for the IPO and Needham & Company was co-manager. What other stocks do shareholders of Aeglea BioTherapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Aeglea BioTherapeutics investors own include Bristol-Myers Squibb (BMY), Athenex (ATNX), Dynavax Technologies (DVAX), Enterprise Products Partners (EPD), Amarin (AMRN), Axsome Therapeutics (AXSM) and AbbVie (ABBV). Company Calendar Last Earnings11/04/2021Today5/10/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry Pharmaceutical preparations Sub-IndustryN/A Current SymbolNASDAQ:AGLE CIK1636282 Webwww.aegleabio.com Phone(512) 942-2935Fax512-872-5121Employees69Year FoundedN/AProfitability EPS (Most Recent Fiscal Year)($75.59) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income$-83,820,000.00 Net Margins-22,195.36% Pretax Margin-27,931.12% Return on Equity-132.05% Return on Assets-146.87% Debt Debt-to-Equity RatioN/A Current Ratio4.59 Quick Ratio4.59 Sales & Book Value Annual Sales$2.33 million Price / Sales0.00 Cash FlowN/A Price / Cash FlowN/A Book Value($60.61) per share Price / BookN/AMiscellaneous Outstanding Shares4,050,000Free Float3,782,000Market Cap$48.64 million OptionableOptionable Beta2.57 Social Links A Beginner's Guide to Investing in CannabisUnlock your free copy of MarketBeat's comprehensive guide to pot stock investing and discover which cannabis companies are poised for growth. Plus, you'll get exclusive access to our daily newsletter with expert stock recommendations from Wall Street's top analysts.Get This Free Report This page (NASDAQ:AGLE) was last updated on 5/10/2025 by MarketBeat.com Staff From Our PartnersWhite House to reset Social Security?Elon Musk's parting DOGE gift looks set to shock America... A single announcement by July 22nd could soon b...Altimetry | SponsoredURGENT: Someone's Moving Gold Out of London...People who don’t understand the gold market are about to lose a lot of money. Unfortunately, most so-called “g...Golden Portfolio | SponsoredThis Is The Moment You Betray Trump (Or Prove Them Wrong)They said you wouldn’t last—that Bidenflation, Wall Street selloffs, and DEI funds would break your loyalty to...Colonial Metals | SponsoredThis robot is coming to 65 million Americans … this year.The Robotics Revolution has arrived. And not surprisingly, Nvidia is leading the way. 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