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Apellis Pharmaceuticals (APLS) Institutional Ownership

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Institutional Ownership Changes (13F Filings) for Apellis Pharmaceuticals (NASDAQ:APLS)

Current
Institutional Ownership
Percentage
96.29%
Number of
Institutional Buyers
(last 12 months)
175
Total
Institutional Inflows
(last 12 months)
$1.08B
Number of
Institutional Sellers
(last 12 months)
93
Total
Institutional Outflows
(last 12 months)
$537.60M
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APLS Institutional Buying and Selling by Quarter

Apellis Pharmaceuticals Major Shareholders & Ownership History

Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
6/16/2026Empowered Funds LLC148,038$5.96M0.0%+1,006.3%0.116%
6/15/2026Carmignac Gestion35,127$1.41M0.0%N/A0.027%
5/29/2026Perceptive Advisors LLC80,956$3.26M0.1%N/A0.063%
5/28/2026 Carlson Capital L.P.30,000$1.21M0.4%N/A0.023%
5/19/2026Bank of America Corp DE1,190,864$47.91M0.0%+24.5%0.930%
5/19/2026Janus Henderson Group PLC252,130$10.14M0.0%+9.5%0.197%
5/19/2026Oddo BHF Asset Management Sas825,000$33.19M1.3%N/A0.644%
5/18/2026ADAR1 Capital Management LLC72,500$2.92M0.2%+262.5%0.057%
5/18/2026 EverSource Wealth Advisors LLC1,219$49K0.0%-53.2%0.001%
5/18/2026California State Teachers Retirement System94,833$3.82M0.0%+29.5%0.074%
5/18/2026Readystate Asset Management LP34,100$1.37M0.1%N/A0.027%
5/18/2026Royal Bank of Canada126,701$5.10M0.0%+42.9%0.099%
5/18/2026Rock Springs Capital Management LP162,750$6.55M0.4%+8.1%0.127%
5/18/2026Empowered Funds LLC148,038$5.96M0.0%+1,006.3%0.116%
5/18/2026Exome Asset Management LLC85,517$3.44M1.8%-37.0%0.067%
5/16/2026The Manufacturers Life Insurance Company 24,765$996K0.0%+8.4%0.019%
5/16/2026Quantinno Capital Management LP121,270$4.88M0.0%+281.8%0.095%
5/16/2026SummitTX Capital L.P.20,351$819K0.0%N/A0.016%
5/15/2026Weiss Asset Management LP700,000$28.16M0.5%N/A0.547%
5/15/2026Absolute Gestao de Investimentos Ltda.450,000$18.10M2.1%N/A0.352%
5/15/2026Kryger Capital LLC1,100,000$44.25M3.1%N/A0.859%
5/14/2026Healthcare of Ontario Pension Plan Trust Fund1,202,100$48.36M0.1%N/A0.939%
5/14/2026Renaissance Technologies LLC935,958$37.65M0.1%+47.8%0.731%
5/14/2026 Gabelli Funds LLC321,200$12.92M0.1%N/A0.251%
5/14/2026 GABELLI & Co INVESTMENT ADVISERS INC.200,600$8.07M1.2%N/A0.157%
5/14/2026 Gamco Investors INC. ET AL21,000$845K0.0%N/A0.016%
5/14/2026Public Employees Retirement System of Ohio31,378$1.26M0.0%-3.3%0.025%
5/14/2026Capula Management Ltd56,266$2.26M0.0%N/A0.044%
5/14/2026Sei Investments Co.11,747$473K0.0%-80.5%0.009%
5/14/2026 State of Wyoming1,288$52K0.0%N/A0.001%
5/13/2026 Transmarket Holdings LP23,585$949K0.5%N/A0.018%
5/13/2026 First Trust Advisors LP903,637$36.35M0.0%+82.2%0.706%
5/8/2026 PNC Financial Services Group Inc.54,474$2.19M0.0%+1.8%0.043%
5/7/2026 Dimensional Fund Advisors LP1,338,995$53.75M0.0%+640.1%1.046%
5/5/2026 Bank of New York Mellon Corp524,789$21.11M0.0%+93.0%0.410%
5/5/2026 Maryland State Retirement & Pension System20,816$837K0.0%N/A0.016%
5/4/2026 ABC Arbitrage SA83,317$3.35M0.4%N/A0.065%
5/4/2026 Principal Financial Group Inc.499,053$20.08M0.0%N/A0.390%
5/4/2026 Teachers Retirement System of The State of Kentucky25,000$1.01M0.0%N/A0.020%
5/1/2026 Commonwealth of Pennsylvania Public School Empls Retrmt SYS25,344$1.02M0.0%N/A0.020%
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5/1/2026 Fifth Third Bancorp22,102$889K0.0%N/A0.017%
4/30/2026Hsbc Holdings PLC5,944$239K0.0%N/A0.005%
4/30/2026 Granite Investment Partners LLC231,917$9.33M0.6%-29.1%0.181%
4/30/2026 Oregon Public Employees Retirement Fund23,400$941K0.0%N/A0.018%
4/29/2026 Burney Co.61,578$2.48M0.1%N/A0.048%
4/27/2026 Chicago Capital Management LLC190,000$7.64M0.0%N/A0.149%
4/27/2026 New York State Teachers Retirement System18,299$736K0.0%N/A0.014%
4/27/2026 Y Intercept Hong Kong Ltd8,536$343K0.0%-73.0%0.007%
4/22/2026 Pictet Asset Management Holding SA426,821$17.17M0.0%+9.2%0.334%
4/21/2026 Louisiana State Employees Retirement System45,400$1.83M0.0%N/A0.036%
2/19/2026T. Rowe Price Investment Management Inc.1,974$50K0.0%-96.0%0.002%
2/19/2026Invesco Ltd.225,976$5.68M0.0%+23.5%0.179%
2/18/2026 Mercer Global Advisors Inc. ADV17,668$444K0.0%-54.7%0.014%
2/18/2026 Vident Advisory LLC15,553$391K0.0%-56.0%0.012%
2/18/2026Mackenzie Financial Corp96,211$2.42M0.0%+25.4%0.076%
2/18/2026 NewEdge Advisors LLC14,570$366K0.0%N/A0.012%
2/18/2026Voloridge Investment Management LLC461,186$11.59M0.0%-53.5%0.365%
2/18/2026 Virtus Investment Advisers LLC27,086$680K0.2%+17.4%0.021%
2/18/2026Twinbeech Capital LP13,152$330K0.0%+47.3%0.010%
2/18/2026Sphera Funds Management LTD.250,961$6.30M1.2%+294.2%0.198%
2/18/2026Suvretta Capital Management LLC4,139,426$103.98M2.1%+43.8%3.272%
2/18/2026 Quadrature Capital Ltd24,075$605K0.0%N/A0.019%
2/18/2026RTW Investments LP7,666,764$192.59M1.9%N/A6.059%
2/18/2026Orbimed Advisors LLC2,429,868$61.04M1.3%-5.6%1.920%
2/18/2026Odyssean LLC19,207$482K0.3%N/A0.015%
2/18/2026Millennium Management LLC946,459$23.78M0.0%-29.6%0.748%
2/18/2026Man Group plc144,271$3.62M0.0%+114.7%0.114%
2/18/2026Ishara Investments LP50,000$1.26M1.5%N/A0.040%
2/18/2026Janus Henderson Group PLC230,320$5.79M0.0%+569.3%0.182%
2/18/2026Gotham Asset Management LLC168,455$4.23M0.0%+32.5%0.133%
2/18/2026Elmind Capital LP50,000$1.26M0.4%N/A0.040%
2/18/2026Apis Capital Advisors LLC192,000$4.82M0.8%N/A0.152%
2/18/2026683 Capital Management LLC330,000$8.29M0.4%+14.6%0.261%
2/17/2026Freestone Grove Partners LP12,537$315K0.0%N/A0.010%
2/17/2026 Guggenheim Capital LLC36,647$921K0.0%+8.3%0.029%
2/17/2026AQR Capital Management LLC2,276,687$57.19M0.0%-49.3%1.799%
2/17/2026Jain Global LLC16,877$424K0.0%N/A0.013%
2/17/2026Trexquant Investment LP194,592$4.89M0.0%-66.8%0.154%
2/17/2026 Amundi30,721$772K0.0%-97.9%0.024%
2/17/2026Jump Financial LLC193,876$4.87M0.1%-30.2%0.153%
2/17/2026Price T Rowe Associates Inc. MD95,035$2.39M0.0%-3.0%0.075%
2/17/2026T. Rowe Price Investment Management Inc.1,974$50K0.0%-96.0%0.002%
2/17/2026Rock Springs Capital Management LP150,500$3.78M0.2%+63.6%0.119%
2/17/2026Quantitative Investment Management LLC8,611$216K0.0%N/A0.007%
2/17/2026Integral Health Asset Management LLC200,000$5.02M0.2%-20.0%0.158%
2/17/2026Public Employees Retirement System of Ohio32,448$815K0.0%-3.7%0.026%
2/17/2026State of Wisconsin Investment Board66,916$1.68M0.0%-22.0%0.053%
2/17/2026ExodusPoint Capital Management LP171,156$4.30M0.0%-12.1%0.135%
2/17/2026Royal Bank of Canada88,687$2.23M0.0%-39.3%0.070%
2/17/2026Graham Capital Management L.P.9,302$234K0.0%-59.9%0.007%
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2/17/2026Polar Capital Holdings Plc3,706,510$93.11M0.4%+39.9%2.929%
2/16/2026Squarepoint Ops LLC192,156$4.83M0.0%+140.7%0.152%
2/16/2026 Panagora Asset Management Inc.42,134$1.06M0.0%N/A0.033%
2/16/2026Maven Securities LTD15,000$377K0.0%N/A0.012%
2/16/2026Entropy Technologies LP23,128$581K0.0%-6.0%0.018%
2/13/2026Marshall Wace LLP990,848$24.89M0.0%+149.8%0.783%
2/13/2026CANADA LIFE ASSURANCE Co8,495$214K0.0%-52.1%0.007%
2/13/2026Bridgewater Associates LP143,805$3.61M0.0%N/A0.114%
2/13/2026 Stifel Financial Corp36,661$921K0.0%N/A0.029%
2/13/2026Hudson Bay Capital Management LP1,179,828$29.64M0.1%+181.9%0.932%


APLS Institutional Ownership - Frequently Asked Questions

During the previous two years, 303 institutional investors and hedge funds held shares of Apellis Pharmaceuticals. The most heavily invested institutionals were Avoro Capital Advisors LLC ($390.01M), Vanguard Group Inc. ($268.15M), EcoR1 Capital LLC ($260.16M), Morgan Stanley ($230.43M), RTW Investments LP ($192.59M), Deep Track Capital LP ($181.05M), and State Street Corp ($115.89M).Learn more on Apellis Pharmaceuticals' institutional investors.

96.29% of Apellis Pharmaceuticals' stock is owned by institutional investors. Learn more on APLS's institutional investor holdings.

Of the 271 institutional investors that purchased Apellis Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: RTW Investments LP ($7.67M), AQR Capital Management LLC ($5.35M), Norges Bank ($4.65M), Marshall Wace LLP ($3.34M), Polar Capital Holdings Plc ($2.85M), Braidwell LP ($2.51M), and Suvretta Capital Management LLC ($2.05M).

Institutional investors have bought a total of 39,342,637 shares in the last 24 months. This purchase volume represents approximately $1.08B in transactions.

Of the 88 institutional investors that sold Apellis Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: AQR Capital Management LLC ($3.70M), Jennison Associates LLC ($2.84M), Marshall Wace LLP ($2.31M), Bank of America Corp DE ($1.65M), Amundi ($1.57M), UBS Group AG ($1.31M), and Octagon Capital Advisors LP ($1.19M).

Institutional investors have sold a total of 22,907,405 shares in the last 24 months. This volume of shares sold represents approximately $537.60M in transactions.



Institutional ownership data for NASDAQ:APLS is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 6/16/2026. New 13F filings are added each quarter as they're published.
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