This company has been marked as potentially delisted and may not be actively trading. NASDAQ:ONCE Spark Therapeutics (ONCE) Stock Price, News & Analysis Add Compare Share Share Stock Analysis Stock AnalysisBuy This Stock About Spark Therapeutics Stock (NASDAQ:ONCE) 30 days 90 days 365 days Advanced Chart Get Spark Therapeutics alerts:Sign Up Key Stats Today's Range$0.18▼$0.1850-Day Range$110.05▼$113.5752-Week Range$34.53▼$114.20VolumeN/AAverage Volume891,560 shsMarket Capitalization$6.94 millionP/E RatioN/ADividend YieldN/APrice TargetN/AConsensus RatingN/A Company OverviewSpark Therapeutics, Inc. focuses on the development of gene therapy products for patients suffering from debilitating genetic diseases. Its products include LUXTURNA (voretigene neparvovec) for the treatment of patients with confirmed biallelic RPE65 mutation-associated retinal dystrophy and viable retinal cells. The company's gene therapy product candidates comprise SPK-8011 and SPK-8016 for hemophilia; SPK-7001 for choroideremia; and SPK-9001 for hemophilia B. It is also developing other liver-directed gene therapies, including SPK-3006 for Pompe disease; and neurodegenerative disease product candidates to address Huntington's disease and others, as well as TPP1 deficiency, which is a form of Batten disease. The company's preclinical programs targets inherited retinal diseases, including Stargardt's disease. The company has collaboration agreement with Pfizer, Inc. for the development and commercialization of SPK-FIX product candidates in its gene therapy program for the treatment of hemophilia B. It also has licensing and commercialization agreement with Novartis to develop and commercialize voretigene neparvovec outside the United States. Spark Therapeutics, Inc. was founded in 2013 and is headquartered in Philadelphia, Pennsylvania.Read More… Receive ONCE Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Spark Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Email Address ONCE Stock News HeadlinesHow Spark's layoffs could affect University City real estateApril 11, 2025 | bizjournals.comDespite Spark's massive layoffs, co-founder Jeff Marrazzo says its legacy will endureApril 9, 2025 | bizjournals.comBanks aren’t ready for this altcoin—are you?Our expert analysts have identified a $100 billion gap in the crypto market. Only one project is perfectly positioned to fill it…June 14, 2025 | Crypto 101 Media (Ad)Spark Therapeutics is laying off 337 people, more than half its workforce, starting in MayApril 4, 2025 | msn.comSpark Therapeutics, a Philly biotech pioneer, is being restructured amid financial write-downsMarch 4, 2025 | msn.comPfizer shelves Beqvez, a Spark Therapeutics developed productFebruary 24, 2025 | bizjournals.comSpark Therapeutics co-founder back at the helm of a Philadelphia gene therapy companyJanuary 14, 2025 | bizjournals.comBitcoin breaks $81,000 for first time on Trump trades; UK government sells £1bn of NatWest shares – business liveNovember 11, 2024 | msn.comSee More Headlines ONCE Stock Analysis - Frequently Asked Questions How were Spark Therapeutics' earnings last quarter? Spark Therapeutics Inc (NASDAQ:ONCE) issued its earnings results on Tuesday, August, 7th. The biotechnology company reported ($0.77) EPS for the quarter, missing analysts' consensus estimates of ($0.43) by $0.34. The biotechnology company earned $25.19 million during the quarter, compared to analysts' expectations of $29.44 million. Spark Therapeutics had a negative net margin of 358.41% and a negative trailing twelve-month return on equity of 59.10%. When did Spark Therapeutics IPO? Spark Therapeutics (ONCE) raised $88 million in an IPO on Friday, January 30th 2015. The company issued 5,500,000 shares at a price of $15.00-$17.00 per share. J.P. Morgan and Credit Suisse served as the underwriters for the IPO and Cowen and Company and Sanford C. Bernstein were co-managers. What other stocks do shareholders of Spark Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Spark Therapeutics investors own include Bristol-Myers Squibb (BMY), NVIDIA (NVDA), Brainstorm Cell Therapeutics (BCLI), Meta Platforms (META), Alibaba Group (BABA), Gilead Sciences (GILD) and Micron Technology (MU). Company Calendar Last Earnings8/07/2018Today6/14/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry Biological Products, Except Diagnostic Sub-IndustryN/A Current SymbolNASDAQ:ONCE CIK1609351 Webwww.sparktx.com Phone888-772-7560FaxN/AEmployees368Year FoundedN/AProfitability EPS (Most Recent Fiscal Year)($2.11) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$78.82 million Net Margins-358.41% Pretax MarginN/A Return on Equity-59.10% Return on Assets-33.13% Debt Debt-to-Equity Ratio0.35 Current Ratio4.67 Quick Ratio4.35 Sales & Book Value Annual Sales$64.72 million Price / Sales0.11 Cash FlowN/A Price / Cash FlowN/A Book Value$13.15 per share Price / Book0.01Miscellaneous Outstanding Shares38,523,000Free FloatN/AMarket Cap$6.94 million OptionableNo Data Beta2.05 Options Trading Made Easy - Download NowLearn the basics of options trading and how to use them to boost returns and manage risk with this free report from MarketBeat. Click the link below to get your free copy.Get This Free Report This page (NASDAQ:ONCE) was last updated on 6/14/2025 by MarketBeat.com Staff From Our PartnersThe Trump Dump is starting; Get out of stocks now?The first 365 days of the Trump presidency… Will be the best time to get rich in American history.Paradigm Press | SponsoredAn AI run of epic proportions is only getting startedI just put together an urgent new presentation that you need to see right away. 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