| 5/13/2019 | Geraldine Henwood | CEO | Sell | 144,806 | $8.89 | $1,287,325.34 | 342,947 |  |
| 5/24/2018 | Healthcare Master Fun Broadfin | Major Shareholder | Sell | 188,000 | $5.81 | $1,092,280.00 | | |
| 3/13/2018 | Healthcare Master Fun Broadfin | Major Shareholder | Sell | 200,000 | $10.07 | $2,014,000.00 | | |
| 1/3/2018 | Scp Vitalife Partners (Israel) | Major Shareholder | Sell | 12,964 | $8.88 | $115,120.32 | 734,269 | |
| 12/29/2017 | Scp Vitalife Partners Ii Lp | Major Shareholder | Sell | 18,231 | $9.27 | $169,001.37 | | |
| 12/28/2017 | Scp Vitalife Partners (Israel) | Major Shareholder | Sell | 1,980 | $9.44 | $18,691.20 | 744,708 | |
| 12/27/2017 | Scp Vitalife Partners Ii Lp | Major Shareholder | Sell | 13,189 | $9.56 | $126,086.84 | 2,243,064 | |
| 12/21/2017 | Healthcare Master Fun Broadfin | Major Shareholder | Sell | 76,000 | $9.87 | $750,120.00 | | |
| 12/13/2017 | Healthcare Master Fun Broadfin | Major Shareholder | Sell | 93,237 | $9.86 | $919,316.82 | | |
| 12/5/2017 | Healthcare Master Fun Broadfin | Major Shareholder | Sell | 100,000 | $10.00 | $1,000,000.00 | | |
| 11/30/2017 | Healthcare Master Fun Broadfin | Major Shareholder | Sell | 222,616 | $9.58 | $2,132,661.28 | | |
| 11/28/2017 | Healthcare Master Fun Broadfin | Major Shareholder | Sell | 47,549 | $9.64 | $458,372.36 | | |
| 11/24/2017 | Healthcare Master Fun Broadfin | Major Shareholder | Sell | 172,208 | $9.45 | $1,627,365.60 | | |
| 11/21/2017 | Healthcare Master Fun Broadfin | Major Shareholder | Sell | 102,440 | $9.50 | $973,180.00 | | |
| 6/14/2017 | James E Flynn | Insider | Sell | 110,447 | $6.39 | $705,756.33 | | |
| 6/13/2017 | James E Flynn | Major Shareholder | Sell | 32,447 | $6.59 | $213,825.73 | | |
| 6/12/2017 | James E Flynn | Major Shareholder | Sell | 10,000 | $6.74 | $67,400.00 | | |
| 6/8/2017 | James E Flynn | Insider | Sell | 62,868 | $7.06 | $443,848.08 | | |
| 5/12/2017 | Stonepine Capital Management, | Major Shareholder | Sell | 510,000 | $7.40 | $3,774,000.00 | | |
| 5/11/2017 | Stonepine Capital Management, | Major Shareholder | Sell | 244,629 | $7.65 | $1,871,411.85 | | |
| 5/4/2017 | Stonepine Capital Management, | Major Shareholder | Sell | 217,308 | $7.70 | $1,673,271.60 | | |
| 3/16/2017 | Scp Vitalife Partners Ii Lp | Major Shareholder | Sell | 44,977 | $8.00 | $359,816.00 | 2,276,571 | |
| 2/17/2017 | Scp Vitalife Partners Ii Lp | Major Shareholder | Sell | 9,983 | $7.59 | $75,770.97 | 2,292,899 | |
| 2/16/2017 | Scp Vitalife Partners (Israel) | Major Shareholder | Sell | 4,030 | $7.89 | $31,796.70 | 772,714 | |
| 12/16/2016 | Karen Flynn | Director | Buy | 800 | $6.71 | $5,368.00 | 800 | |
| 12/15/2016 | Alfred Altomari | Director | Buy | 1,500 | $6.55 | $9,825.00 | 1,500 | |
| 12/13/2016 | Healthcare Master Fun Broadfin | Major Shareholder | Buy | 650,000 | $6.00 | $3,900,000.00 | | |
| 8/16/2016 | Healthcare Master Fun Broadfin | Major Shareholder | Buy | 390,000 | $7.50 | $2,925,000.00 | | |
| 5/31/2016 | Stewart Mccallum | Insider | Buy | 1,250 | $8.22 | $10,275.00 | 1,000 | |
| 5/23/2016 | Randall Mack | VP | Buy | 2,000 | $6.30 | $12,600.00 | 2,000 | |
| 5/23/2016 | Scp Vitalife Partners (Israel) | Major Shareholder | Sell | 2,503 | $6.30 | $15,768.90 | 776,131 | |
| 5/20/2016 | Scp Vitalife Partners (Israel) | Major Shareholder | Sell | 6,260 | $6.46 | $40,439.60 | 783,642 | |
| 5/20/2016 | Winston J Churchill | Director | Sell | 58,331 | $7.91 | $461,398.21 | | |
| 5/19/2016 | Donna Nichols | CAO | Buy | 1,140 | $6.48 | $7,387.20 | 2,340 | |
| 11/27/2015 | Scp Vitalife Partners Ii Lp | major shareholder | Sell | 11,385 | $9.00 | $102,465.00 | 2,349,511 | |
| 11/24/2015 | Scp Vitalife Partners (Israel) | major shareholder | Sell | 4,393 | $9.00 | $39,537.00 | 788,847 | |
| 7/7/2015 | Healthcare Master Fun Broadfin | Major Shareholder | Buy | 646,553 | $11.60 | $7,500,014.80 | | |
| 6/8/2015 | Geraldine Henwood | CEO | Buy | 4,500 | $8.92 | $40,140.00 | | |
| 6/5/2015 | Charles Garner | CFO | Buy | 2,000 | $8.50 | $17,000.00 | | |
| 12/2/2014 | Healthcare Master Fun Broadfin | Major Shareholder | Buy | 241,338 | $2.50 | $603,345.00 | | |
| 5/15/2014 | Charles Garner | CFO | Buy | 3,000 | $6.69 | $20,070.00 | | |
| 5/15/2014 | Donna Nichols | CAO | Buy | 1,200 | $6.66 | $7,992.00 | | |
