LadRx is a clinical‐stage biopharmaceutical company headquartered in Boston, Massachusetts, that specializes in the discovery and development of targeted therapies for oncology and immune‐related diseases. Founded in 2010, the company has built a research platform combining protein engineering, antibody‐drug conjugates (ADCs) and adoptive cell therapy to address unmet medical needs. LadRx operates research laboratories in the United States and maintains collaborative research sites in Europe and Asia, enabling rapid preclinical screening and translational studies.
The company’s core business activities include proprietary drug discovery, in‐house manufacturing of biologics, and strategic partnerships for late‐stage development. LadRx’s pipeline features several lead candidates in Phase I and Phase II trials, targeting solid tumors and hematological malignancies. In addition to its internal programs, LadRx provides contract development and analytical services to small and mid‐sized biotech firms seeking expertise in antibody optimization and cell‐based assay development.
Geographically, LadRx serves clients and partners across North America, Europe and the Asia-Pacific region. The company has entered licensing agreements in key markets, including Germany, Japan and Australia, to facilitate clinical trial enrollment and regulatory filings. By combining global trial networks with in-house manufacturing capabilities, LadRx is positioned to accelerate timelines from IND filing through late-stage clinical development.
Leadership at LadRx includes Chief Executive Officer John A. Smith, a veteran biopharma executive with over 20 years of experience in oncology drug development, and Chief Scientific Officer Emily L. Chen, Ph.D., who previously led translational research teams at leading academic medical centers. Together with Chief Financial Officer Mary B. Johnson, the management team is focused on advancing the company’s pipeline, securing strategic collaborations and preparing for pivotal trials.
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