OTCMKTS:SPHDF Santhera Pharmaceuticals (SPHDF) Stock Price, News & Analysis $18.40 0.00 (0.00%) As of 09/17/2025 Add Compare Share Share Stock Analysis Stock AnalysisChartHeadlinesShort InterestBuy This Stock About Santhera Pharmaceuticals Stock (OTCMKTS:SPHDF) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SPHDF alerts:Sign Up Key Stats Today's Range$18.40▼$18.4050-Day Range$14.75▼$18.4052-Week Range$14.75▼$19.00VolumeN/AAverage Volume229 shsMarket CapitalizationN/AP/E RatioN/ADividend YieldN/APrice TargetN/AConsensus RatingN/A Company Overview Santhera Pharmaceuticals is a Swiss specialty pharmaceutical company focused on the development and commercialization of innovative therapies for rare neuromuscular and pulmonary diseases. Headquartered in Pratteln, Switzerland, the company concentrates on addressing high unmet medical needs in conditions such as Duchenne muscular dystrophy (DMD), limb‐girdle muscular dystrophies and other mitochondrial or neuromuscular disorders. Santhera’s corporate strategy emphasizes both in‐house development and strategic partnerships to advance its drug candidates through clinical trials and bring approved therapies to market. The company’s flagship marketed product is Raxone (idebenone), a synthetic analogue of coenzyme Q10 that received marketing authorization in Europe for the treatment of visual impairment in patients with Leber’s hereditary optic neuropathy (LHON). In addition to Raxone’s role in LHON, Santhera has expanded the use of idebenone under the brand name Puldysa in certain European countries for the maintenance of respiratory function in patients with DMD. Santhera’s pipeline includes vamorolone, a novel corticosteroid analogue being developed in collaboration with ReveraGen BioPharma for boys with DMD, as well as earlier‐stage programs targeting rare mitochondrial and muscle disorders. Santhera serves patients and healthcare providers across Europe and North America through a network of subsidiaries and distribution partners. The company was founded in the mid‐1990s and maintains research and commercial operations in key markets, including Germany, Italy and the United States. Santhera continues to leverage its expertise in rare disease drug development, regulatory strategy and patient advocacy to expand its portfolio and reach, aiming to deliver new treatment options for underserved patient populations.AI Generated. May Contain Errors. Read More Santhera Pharmaceuticals Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks9th Percentile Overall ScoreSPHDF MarketRank™: Santhera Pharmaceuticals scored higher than 9% of companies evaluated by MarketBeat. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's OpinionN/AAnalyst RatingN/A Consensus RatingThere is not enough analysis data for Santhera Pharmaceuticals. Earnings and Valuation0.0 / 5Proj. Earnings GrowthN/A Price to Earnings Ratio vs. the MarketThe P/E ratio of Santhera Pharmaceuticals is -13.43, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Santhera Pharmaceuticals is -13.43, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings. Short Interest4.0 / 5Short Interest LevelHealthy Percentage of Shares ShortedShort Interest Ratio / Days to CoverSanthera Pharmaceuticals has a short interest ratio ("days to cover") of 0, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Santhera Pharmaceuticals has recently decreased by 42.86%, indicating that investor sentiment is improving significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldSanthera Pharmaceuticals does not currently pay a dividend.Dividend GrowthSanthera Pharmaceuticals does not have a long track record of dividend growth. Sustainability and ESGN/AEnvironmental ScoreN/A Percentage of Shares ShortedShort Interest Ratio / Days to CoverSanthera Pharmaceuticals has a short interest ratio ("days to cover") of 0, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Santhera Pharmaceuticals has recently decreased by 42.86%, indicating that investor sentiment is improving significantly. News and Social Media2.2 / 5News SentimentN/A News SentimentSanthera Pharmaceuticals has a news sentiment score of 1.00. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.63 average news sentiment score of Medical companies. Company Ownership0.0 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Santhera Pharmaceuticals insiders have not sold or bought any company stock.Percentage Held by InstitutionsOnly 8.23% of the stock of Santhera Pharmaceuticals is held by institutions.Read more about Santhera Pharmaceuticals' insider trading history. Receive SPHDF Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Santhera Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. SPHDF Stock News HeadlinesSanthera Enters into Agreement with Ikris Pharma Network for the Distribution of AGAMREE® (Vamorolone) in IndiaAugust 29, 2025 | finance.yahoo.comSanthera Secures Agreement with Uniphar for the Distribution of AGAMREE® (Vamorolone) in five GCC (Gulf Cooperation Council) CountriesAugust 20, 2025 | finance.yahoo.comAlert: Prepare for Trump's Dollar OverhaulPresident Trump just signed a game-changing law… That could soon upgrade the U.S. dollar in your checking and savings account… With this better, more technologically advanced dollar. President Trump himself called it a "big innovation"… And said that this new form of currency represents "American brilliance at its best." | Brownstone Research (Ad)Santhera Secures Agreement with GEN for the Distribution of AGAMREE® (Vamorolone) in TürkiyeAugust 13, 2025 | finance.yahoo.comSPHDF - Santhera Pharmaceuticals Holding AG Key Metrics - MorningstarJune 26, 2025 | morningstar.comMSanthera shares updates on commercial rollout of AGAMREE®April 16, 2025 | markets.businessinsider.comSanthera Pharmaceuticals Holding AG: Santhera proposes Dr. Melanie Rolli as new member of Board of DirectorsMarch 27, 2025 | finanznachrichten.deSanthera to share latest on commercial rollout of AGAMREE® and future strategic priorities at Capital Markets DayMarch 24, 2025 | markets.businessinsider.comSee More Headlines SPHDF Stock Analysis - Frequently Asked Questions How have SPHDF shares performed this year? Santhera Pharmaceuticals' stock was trading at $9.42 at the beginning of the year. Since then, SPHDF shares have increased by 95.3% and is now trading at $18.40. When did Santhera Pharmaceuticals' stock split? Santhera Pharmaceuticals shares reverse split on the morning of Monday, July 3rd 2023.The 1-10 reverse split was announced on Monday, July 3rd 2023. The number of shares owned by shareholders was adjusted after the closing bell on Monday, July 3rd 2023. An investor that had 100 shares of stock prior to the reverse split would have 10 shares after the split. How do I buy shares of Santhera Pharmaceuticals? Shares of SPHDF stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. Industry, Sector and Symbol Stock ExchangeOTCMKTS SectorMedical Industry Biotechnology Sub-IndustryN/A Current SymbolOTCMKTS:SPHDF CIKN/A Webwww.santhera.com Phone(161) 906-8950FaxN/AEmployees45Year FoundedN/AProfitability EPS (Trailing Twelve Months)N/A Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet IncomeN/A Net MarginsN/A Pretax MarginN/A Return on EquityN/A Return on AssetsN/A Debt Debt-to-Equity RatioN/A Current RatioN/A Quick RatioN/A Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book ValueN/A Price / BookN/AMiscellaneous Outstanding SharesN/AFree FloatN/AMarket CapN/A OptionableNot Optionable BetaN/A 5G Stocks: The Path Forward is ProfitableEnter your email address and we'll send you MarketBeat's guide to investing in 5G and which 5G stocks show the most promise. Get This Free Report This page (OTCMKTS:SPHDF) was last updated on 9/19/2025 by MarketBeat.com Staff From Our PartnersTrump’s national nightmare is herePorter Stansberry and Jeff Brown say a new U.S. national emergency is already underway — and it could trigger ...Porter & Company | SponsoredHe Called Nvidia at $1.10. Now, He Says THIS Stock Will…The original Magnificent Seven returned 16,894%—turning $7K into $1.18 million. Now, the man who called Nvi...The Oxford Club | SponsoredA New Way to Double Your Retirement Income?Bloomberg reports that a new class of investments is “entering a golden era,” with yields fueling a retail boo...Investors Alley | SponsoredINVESTOR ALERT: Tiny “$3 AI Wonder Stock” on the Verge of Blasting OffRight now, we’re witnessing a monumental shift in the world.Traders Agency | SponsoredStrange crypto pattern discovered by 40-person research teamSomething unusual is happening inside a 40-person crypto research firm. 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