Great Point Partners LLC Top Holdings and 13F Report (2024)

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About Great Point Partners LLC

Investment Activity

Great Point Partners LLC has $641.64 million in total holdings as of March 31, 2024.
Great Point Partners LLC owns shares of 35 different stocks, but just 20 companies or ETFs make up 80% of its holdings.
Approximately 34.64% of the portfolio was purchased this quarter.
About 45.80% of the portfolio was sold this quarter.
This quarter, Great Point Partners LLC has purchased 34 new stocks and bought additional shares in 11 stocks.
Great Point Partners LLC sold shares of 8 stocks and completely divested from 9 stocks this quarter.

Largest Holdings

NEUROGENE INC: $51,118,412
Alpine Immune Sciences: $44,733,700
UroGen Pharma: $39,308,175
ABIVAX SA: $35,585,307
Evolus: $34,300,000

Largest New Holdings this Quarter

Viridian Therapeutics: $23,375,850 Holding
Esperion Therapeutics: $21,440,000 Holding
Mind Medicine (MindMed): $18,800,000 Holding
DIANTHUS THERAPEUTICS INC: $18,750,000 Holding
OUTLOOK THERAPEUTICS INC: $17,671,200 Holding

Largest Purchases this Quarter

Viridian Therapeutics: 1,335,000 shares (about $23.38M)
Esperion Therapeutics: 8,000,000 shares (about $21.44M)
Mind Medicine (MindMed): 2,000,000 shares (about $18.80M)
DIANTHUS THERAPEUTICS INC: 625,000 shares (about $18.75M)
OUTLOOK THERAPEUTICS INC: 1,480,000 shares (about $17.67M)

Largest Sales this Quarter

Alpine Immune Sciences: 2,574,934 shares (about $102.07M)
Cytokinetics: 297,798 shares (about $20.88M)
Immunocore: 178,000 shares (about $11.57M)
Arvinas: 162,969 shares (about $6.73M)
Xenon Pharmaceuticals: 143,852 shares (about $6.19M)

Sector Allocation Over Time

Selling

Neutral

Buying

Latest 13F Holdings and Changes Since Previous Quarterly Filing

Issuer Name	Holdings Value	Approximate Purchase/Sale	Change in Shares	Shares Held	% of Portfolio	Sector
NEUROGENE INC	$51,118,412	$512,156 ▲	1.0%	1,004,291	8.0%	COM
ALPN Alpine Immune Sciences	$44,733,700	$102,070,383 ▼	-69.5%	1,128,499	7.0%	Medical
URGN UroGen Pharma	$39,308,175		0.0%	2,620,545	6.1%	Medical
ABIVAX SA	$35,585,307	$13,420,307 ▲	60.5%	2,488,483	5.5%	SPONSORED ADS
EOLS Evolus	$34,300,000	$6,300,000 ▲	22.5%	2,450,000	5.3%	Medical
PLRX Pliant Therapeutics	$27,592,774	$427,332 ▲	1.6%	1,851,864	4.3%	Medical
APOGEE THERAPEUTICS INC	$26,580,000		0.0%	400,000	4.1%	COM
AVTE Aerovate Therapeutics	$26,248,993	$4,435,500 ▼	-14.5%	887,690	4.1%	Medical
VRDN Viridian Therapeutics	$23,375,850	$23,375,850 ▲	New Holding	1,335,000	3.6%	Medical
ANAB AnaptysBio	$22,001,612		0.0%	976,981	3.4%	Medical
ESPR Esperion Therapeutics	$21,440,000	$21,440,000 ▲	New Holding	8,000,000	3.3%	Medical
INSM Insmed	$21,041,621	$14,912,628 ▲	243.3%	775,585	3.3%	Medical
ACLX Arcellx	$20,865,000	$17,508,239 ▲	521.6%	300,000	3.3%	Medical
XENE Xenon Pharmaceuticals	$19,637,171	$6,192,828 ▼	-24.0%	456,148	3.1%	Medical
MNMD Mind Medicine (MindMed)	$18,800,000	$18,800,000 ▲	New Holding	2,000,000	2.9%	Medical
DIANTHUS THERAPEUTICS INC	$18,750,000	$18,750,000 ▲	New Holding	625,000	2.9%	COM
OUTLOOK THERAPEUTICS INC	$17,671,200	$17,671,200 ▲	New Holding	1,480,000	2.8%	COM
FOLD Amicus Therapeutics	$17,616,990	$2,532,700 ▲	16.8%	1,495,500	2.7%	Medical
OCUL Ocular Therapeutix	$15,731,379	$9,361,379 ▲	147.0%	1,728,723	2.5%	Medical
DVAX Dynavax Technologies	$15,697,657	$15,697,657 ▲	New Holding	1,264,920	2.4%	Medical
CYTK Cytokinetics	$14,176,382	$20,878,617 ▼	-59.6%	202,202	2.2%	Medical
OPTN OptiNose	$12,828,024	$78,287 ▼	-0.6%	8,786,318	2.0%	Medical
JASPER THERAPEUTICS INC	$11,965,668	$11,965,668 ▲	New Holding	407,550	1.9%	COM NEW
ITCI Intra-Cellular Therapies	$10,380,000	$2,725,996 ▲	35.6%	150,000	1.6%	Medical
MRUS Merus	$10,054,659	$9,154,059 ▲	1,016.4%	223,288	1.6%	Medical
VTGN Vistagen Therapeutics	$9,814,121		0.0%	1,858,735	1.5%	Medical
TERN Terns Pharmaceuticals	$8,593,436		0.0%	1,309,975	1.3%	Medical
IMCR Immunocore	$7,475,000	$11,570,000 ▼	-60.8%	115,000	1.2%	Medical
AUTL Autolus Therapeutics	$7,443,335	$7,443,335 ▲	New Holding	1,166,667	1.2%	Medical
PBYI Puma Biotechnology	$7,121,228	$1,326,881 ▲	22.9%	1,343,628	1.1%	Medical
ZURA Zura Bio	$7,087,392	$1,380,758 ▼	-16.3%	2,757,740	1.1%	Medical
HELIX ACQUISITION CORP II	$5,200,000	$5,200,000 ▲	New Holding	500,000	0.8%	CL A ORD SHS
SPYRE THERAPEUTICS INC	$4,741,250		0.0%	125,000	0.7%	COM NEW
KYVERNA THERAPEUTICS INC	$3,726,000	$3,726,000 ▲	New Holding	150,000	0.6%	COM
ARVN Arvinas	$2,935,545	$6,727,361 ▼	-69.6%	71,113	0.5%	Medical
RARE Ultragenyx Pharmaceutical	$0	$30,987,360 ▼	-100.0%	0	0.0%	Medical
RAPT RAPT Therapeutics	$0	$27,328,862 ▼	-100.0%	0	0.0%	Medical
ALKS Alkermes	$0	$24,273,721 ▼	-100.0%	0	0.0%	Medical
PCVX Vaxcyte	$0	$22,608,000 ▼	-100.0%	0	0.0%	Medical
TOURMALINE BIO INC	$0	$17,616,129 ▼	-100.0%	0	0.0%	COM
KRTX Karuna Therapeutics	$0	$9,574,428 ▼	-100.0%	0	0.0%	Medical
SRPT Sarepta Therapeutics	$0	$7,714,400 ▼	-100.0%	0	0.0%	Medical
AXSM Axsome Therapeutics	$0	$395,005 ▼	-100.0%	0	0.0%	Medical
MURAL ONCOLOGY PUB LTD CO	$0	$68,133 ▼	-100.0%	0	0.0%	ORD SHS