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Samsara Biocapital, LLC Top Holdings and 13F Report (2026)

About Samsara Biocapital, LLC

Investment Activity

  • Samsara Biocapital, LLC has $1.22 billion in total holdings as of June 30, 2026.
  • Samsara Biocapital, LLC owns shares of 24 different stocks, but just 7 companies or ETFs make up 80% of its holdings.
  • Approximately 8.45% of the portfolio was purchased this quarter.
  • About 1.82% of the portfolio was sold this quarter.
  • This quarter, Samsara Biocapital, LLC has purchased 22 new stocks and bought additional shares in 2 stocks.
  • Samsara Biocapital, LLC sold shares of 5 stocks and completely divested from 2 stocks this quarter.

Largest Holdings

Scholar Rock
$379,370,860
ALUMIS INC
$178,554,463
SEPTERNA INC
$105,464,297
ALAMAR BIOSCIENCES INC
$67,191,598

Largest New Holdings this Quarter

010911105 - ALAMAR BIOSCIENCES INC
$67,191,598 Holding
698955101 - PARABILIS MEDICINES INC
$15,218,924 Holding
04317A107 - ARTIVA BIOTHERAPEUTICS INC
$9,262,152 Holding
29014R301 - ELOXX PHARMACEUTICALS INC
$5,552,000 Holding

Largest Purchases this Quarter

ALAMAR BIOSCIENCES INC
2,480,310 shares (about $67.19M)
PARABILIS MEDICINES INC
556,044 shares (about $15.22M)
ARTIVA BIOTHERAPEUTICS INC
954,861 shares (about $9.26M)
ELOXX PHARMACEUTICALS INC
400,000 shares (about $5.55M)
Inventiva
1,120,000 shares (about $4.23M)

Largest Sales this Quarter

JADE BIOSCIENCES INC
232,561 shares (about $5.17M)
UPSTREAM BIO INC
382,330 shares (about $2.65M)
X4 PHARMACEUTICALS INC
436,979 shares (about $2.04M)
KALARIS THERAPEUTICS INC
66,906 shares (about $272.31K)
ABIVAX SA
1,486 shares (about $198.02K)

Sector Allocation Over Time

Map of 500 Largest Holdings ofSamsara Biocapital, LLC

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
Scholar Rock Holding Corporation stock logo
SRRK
Scholar Rock
$379,370,8600.0%6,897,65231.2%Healthcare
ALUMIS INC
$178,554,4630.0%6,345,21914.7%COM
Mineralys Therapeutics, Inc. stock logo
MLYS
Mineralys Therapeutics
$158,400,0660.0%5,871,01813.0%Healthcare
SEPTERNA INC
$105,464,2970.0%3,149,1288.7%COM
ALAMAR BIOSCIENCES INC
$67,191,598$67,191,598 â–²New Holding2,480,3105.5%COMMON STOCK
NEUROGENE INC
$54,003,6440.0%1,717,1274.4%COM
KALARIS THERAPEUTICS INC
$52,426,382$272,307 â–¼-0.5%12,881,1754.3%COM
SPYGLASS PHARMA INC
$46,967,5540.0%2,109,9533.9%COM SHS
SUTRO BIOPHARMA INC
$35,287,3500.0%1,062,8722.9%COM SHS
Inventiva S.A. Sponsored ADR stock logo
IVA
Inventiva
$23,869,963$4,233,600 â–²21.6%6,314,8052.0%Healthcare
JADE BIOSCIENCES INC
$16,359,186$5,167,505 â–¼-24.0%736,2371.3%COM NEW
PARABILIS MEDICINES INC
$15,218,924$15,218,924 â–²New Holding556,0441.3%COM
VTV THERAPEUTICS INC
$11,238,3740.0%298,4960.9%CL A NEW
Aquestive Therapeutics, Inc. stock logo
AQST
Aquestive Therapeutics
$10,400,0000.0%2,500,0000.9%Healthcare
Nkarta, Inc. stock logo
NKTX
Nkarta
$9,926,6950.0%3,507,6660.8%Healthcare
ARTIVA BIOTHERAPEUTICS INC
$9,262,152$9,262,152 â–²New Holding954,8610.8%COM
Rani Therapeutics Holdings, Inc. stock logo
RANI
Rani Therapeutics
$7,884,709$1,421,309 â–²22.0%10,369,1590.6%Healthcare
AGOMAB THERAPEUTICS NV
$7,788,0000.0%600,0000.6%SPONSORED ADS
ABIVAX SA
$7,341,960$198,024 â–¼-2.6%55,0950.6%SPONSORED ADS
X4 PHARMACEUTICALS INC
$6,517,391$2,040,692 â–¼-23.8%1,395,5870.5%COM NEW
ELOXX PHARMACEUTICALS INC
$5,552,000$5,552,000 â–²New Holding400,0000.5%COM NEW
Coherus Oncology, Inc. stock logo
CHRS
Coherus Oncology
$4,799,9990.0%3,428,5710.4%Healthcare
UPSTREAM BIO INC
$2,447,722$2,645,724 â–¼-51.9%353,7170.2%COM
Gossamer Bio, Inc. stock logo
GOSS
Gossamer Bio
$1,188,8330.0%7,222,5590.1%Healthcare
Arcellx, Inc. stock logo
ACLX
Arcellx
$0$6,989,438 â–¼-100.0%00.0%Healthcare
PALVELLA THERAPEUTICS INC NE
$0$4,790,549 â–¼-100.0%00.0%COM

Showing largest 100 holdings. View all holdings.
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