Vr Adviser, LLC Top Holdings and 13F Report (2026) About Vr Adviser, LLCInvestment ActivityVr Adviser, LLC has $2.68 billion in total holdings as of March 31, 2026.Vr Adviser, LLC owns shares of 33 different stocks, but just 14 companies or ETFs make up 80% of its holdings.Approximately 10.76% of the portfolio was purchased this quarter.About 6.21% of the portfolio was sold this quarter.This quarter, Vr Adviser, LLC has purchased 27 new stocks and bought additional shares in 6 stocks.Vr Adviser, LLC sold shares of 6 stocks and completely divested from 2 stocks this quarter.Largest Holdings APOGEE THERAPEUTICS INC $714,882,829Erasca $265,073,898ORUKA THERAPEUTICS INC $203,480,393SPYRE THERAPEUTICS INC $185,893,997KalVista Pharmaceuticals $130,331,383 Largest New Holdings this Quarter 36322Q206 - DAMORA THERAPEUTICS INC $93,333,111 Holding75955J402 - Relmada Therapeutics $33,709,925 Holding88032L605 - TENAX THERAPEUTICS INC $26,787,439 Holding00704R109 - ADLAI NORTYE LTD $22,232,099 Holding15673T100 - Century Therapeutics $19,652,174 Holding Largest Purchases this Quarter DAMORA THERAPEUTICS INC 3,603,595 shares (about $93.33M)Relmada Therapeutics 4,843,380 shares (about $33.71M)TENAX THERAPEUTICS INC 1,675,262 shares (about $26.79M)Ocular Therapeutix 3,031,379 shares (about $25.68M)ADLAI NORTYE LTD 3,212,731 shares (about $22.23M) Largest Sales this Quarter Enliven Therapeutics 1,500,000 shares (about $58.80M)CytomX Therapeutics 5,579,376 shares (about $26.22M)Erasca 1,474,271 shares (about $23.85M)Oric Pharmaceuticals 1,356,465 shares (about $17.19M)KalVista Pharmaceuticals 254,500 shares (about $5.12M) Sector Allocation Over TimeMap of 500 Largest Holdings ofVr Adviser, LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorAPOGEE THERAPEUTICS INC$714,882,8290.0%8,493,32126.7%COMERASErasca$265,073,898$23,853,705 â–¼-8.3%16,382,8129.9%MedicalORUKA THERAPEUTICS INC$203,480,3930.0%4,148,4287.6%COMSPYRE THERAPEUTICS INC$185,893,9970.0%3,685,4486.9%COM NEWKALVKalVista Pharmaceuticals$130,331,383$5,123,085 â–¼-3.8%6,474,4854.9%MedicalDIANTHUS THERAPEUTICS INC$99,025,600$15,105,600 â–²18.0%1,180,0003.7%COMDAMORA THERAPEUTICS INC$93,333,111$93,333,111 â–²New Holding3,603,5953.5%COM NEWOCULOcular Therapeutix$87,638,463$25,675,780 â–²41.4%10,346,9263.3%MedicalCOGTCogent Biosciences$76,980,0000.0%2,000,0002.9%MedicalVRDNViridian Therapeutics$75,945,7880.0%3,882,7092.8%MedicalSVRASavara$75,022,4480.0%13,740,3752.8%MedicalELVNEnliven Therapeutics$67,672,175$58,800,000 â–¼-46.5%1,726,3312.5%MedicalORICOric Pharmaceuticals$54,731,423$17,186,412 â–¼-23.9%4,319,7652.0%MedicalVOR BIOPHARMA INC$54,264,267$19,587,482 â–²56.5%3,041,7192.0%COM NEWMAZE THERAPEUTICS INC$47,820,715$1,595,930 â–²3.5%1,602,0341.8%COMCTMXCytomX Therapeutics$46,915,983$26,223,067 â–¼-35.9%9,982,1241.8%MedicalJADE BIOSCIENCES INC$45,246,1140.0%3,220,3641.7%COM NEWDYNE THERAPEUTICS INC$39,413,0430.0%2,173,9131.5%COMCRESCENT BIOPHARMA INC.$39,193,7910.0%2,133,5761.5%COMZURAZura Bio$38,288,191$6,484,756 â–²20.4%6,434,9901.4%MedicalRLMDRelmada Therapeutics$33,709,925$33,709,925 â–²New Holding4,843,3801.3%MedicalENGENE HOLDINGS INC$32,493,3290.0%4,771,4141.2%COMTENAX THERAPEUTICS INC$26,787,439$26,787,439 â–²New Holding1,675,2621.0%COM NEWADLAI NORTYE LTD$22,232,099$22,232,099 â–²New Holding3,212,7310.8%SPONSORED ADSIPSCCentury Therapeutics$19,652,174$19,652,174 â–²New Holding8,695,6520.7%MedicalCGEMCullinan Therapeutics$19,609,3030.0%1,379,9650.7%MedicalCYBIN INC$18,487,939$54,739 â–²0.3%3,851,6540.7%COM NEWSURROZEN INC$18,437,2800.0%632,9310.7%COM NEWSEPTERNA INC$12,160,526$2,517,191 â–¼-17.1%506,0560.5%COMKORRO BIO INC$11,427,540$11,427,540 â–²New Holding1,009,5000.4%COMALTO NEUROSCIENCE INC$11,240,000$11,240,000 â–²New Holding500,0000.4%COM SHSARTIVA BIOTHERAPEUTICS INC$10,365,6240.0%1,609,5690.4%COMX4 PHARMACEUTICALS INC$1,365,068$1,365,068 â–²New Holding330,5250.1%COM NEWUPSTREAM BIO INC$0$31,746,441 â–¼-100.0%00.0%COMCASICASI Pharmaceuticals$0$839,170 â–¼-100.0%00.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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