Vr Adviser, LLC Top Holdings and 13F Report (2026) About Vr Adviser, LLCInvestment ActivityVr Adviser, LLC has $3.30 billion in total holdings as of June 30, 2026.Vr Adviser, LLC owns shares of 33 different stocks, but just 10 companies or ETFs make up 80% of its holdings.Approximately 2.96% of the portfolio was purchased this quarter.About 11.19% of the portfolio was sold this quarter.This quarter, Vr Adviser, LLC has purchased 33 new stocks and bought additional shares in 5 stocks.Vr Adviser, LLC sold shares of 5 stocks and completely divested from 4 stocks this quarter.Largest Holdings APOGEE THERAPEUTICS INC $1,127,318,496ORUKA THERAPEUTICS INC $394,805,893Erasca $327,777,996SPYRE THERAPEUTICS INC $265,048,073DIANTHUS THERAPEUTICS INC $115,026,400 Largest New Holdings this Quarter 004468500 - Achieve Life Sciences $17,964,239 Holding698955101 - PARABILIS MEDICINES INC $17,106,250 HoldingG75226103 - RESEARCH ALLIANCE CORP III $3,210,000 Holding457637700 - INMED PHARMACEUTICALS INC $50,662 Holding Largest Purchases this Quarter Erasca 1,509,000 shares (about $27.64M)Achieve Life Sciences 2,751,032 shares (about $17.96M)PARABILIS MEDICINES INC 625,000 shares (about $17.11M)Relmada Therapeutics 2,000,925 shares (about $13.85M)X4 PHARMACEUTICALS INC 1,603,728 shares (about $7.49M) Largest Sales this Quarter SPYRE THERAPEUTICS INC 700,000 shares (about $62.15M)Enliven Therapeutics 1,200,000 shares (about $60.90M)CytomX Therapeutics 5,000,000 shares (about $18.75M)Cogent Biosciences 357,834 shares (about $13.85M)Viridian Therapeutics 624,792 shares (about $11.48M) Sector Allocation Over TimeMap of 500 Largest Holdings ofVr Adviser, LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorAPOGEE THERAPEUTICS INC$1,127,318,4960.0%8,493,32134.2%COMORUKA THERAPEUTICS INC$394,805,8930.0%4,148,42812.0%COMERASErasca$327,777,996$27,644,880 â–²9.2%17,891,8129.9%HealthcareSPYRE THERAPEUTICS INC$265,048,073$62,146,000 â–¼-19.0%2,985,4488.0%COM NEWDIANTHUS THERAPEUTICS INC$115,026,4000.0%1,180,0003.5%COMOCULOcular Therapeutix$101,606,8130.0%10,346,9263.1%HealthcareDAMORA THERAPEUTICS INC$93,729,5060.0%3,603,5952.8%COM NEWSVRASavara$90,835,009$6,194,299 â–²7.3%14,745,9432.8%HealthcareJADE BIOSCIENCES INC$71,556,4880.0%3,220,3642.2%COM NEWCOGTCogent Biosciences$63,551,824$13,848,176 â–¼-17.9%1,642,1661.9%HealthcareVRDNViridian Therapeutics$59,847,935$11,477,429 â–¼-16.1%3,257,9171.8%HealthcareVOR BIOPHARMA INC$55,998,0470.0%3,041,7191.7%COM NEWDYNE THERAPEUTICS INC$48,282,6080.0%2,173,9131.5%COMMAZE THERAPEUTICS INC$47,804,6950.0%1,602,0341.4%COMRLMDRelmada Therapeutics$47,362,591$13,846,401 â–²41.3%6,844,3051.4%HealthcareORICOric Pharmaceuticals$46,783,0550.0%4,319,7651.4%HealthcareCRESCENT BIOPHARMA INC.$38,404,3680.0%2,133,5761.2%COMZURAZura Bio$37,966,4410.0%6,434,9901.2%HealthcareADLAI NORTYE LTD$36,946,4070.0%3,212,7311.1%SPONSORED ADSELVNEnliven Therapeutics$26,711,298$60,899,999 â–¼-69.5%526,3310.8%HealthcareCYBIN INC$25,459,4330.0%3,851,6540.8%COM NEWCGEMCullinan Therapeutics$25,129,1630.0%1,379,9650.8%HealthcareIPSCCentury Therapeutics$21,304,3470.0%8,695,6520.6%HealthcareARTIVA BIOTHERAPEUTICS INC$19,822,881$4,210,062 â–²27.0%2,043,5960.6%COMCTMXCytomX Therapeutics$18,682,965$18,750,000 â–¼-50.1%4,982,1240.6%HealthcareACHVAchieve Life Sciences$17,964,239$17,964,239 â–²New Holding2,751,0320.5%HealthcarePARABILIS MEDICINES INC$17,106,250$17,106,250 â–²New Holding625,0000.5%COMSURROZEN INC$16,424,5590.0%632,9310.5%COM NEWKORRO BIO INC$13,305,2100.0%1,009,5000.4%COMALTO NEUROSCIENCE INC$13,195,0000.0%500,0000.4%COM SHSX4 PHARMACEUTICALS INC$9,032,962$7,489,410 â–²485.2%1,934,2530.3%COM NEWRESEARCH ALLIANCE CORP III$3,210,000$3,210,000 â–²New Holding300,0000.1%ORD SHS CL AINMED PHARMACEUTICALS INC$50,662$50,662 â–²New Holding32,6850.0%COM NEWKALVKalVista Pharmaceuticals$0$130,331,383 â–¼-100.0%00.0%HealthcareENGENE HOLDINGS INC$0$32,493,329 â–¼-100.0%00.0%COMTENAX THERAPEUTICS INC$0$26,787,439 â–¼-100.0%00.0%COM NEWSEPTERNA INC$0$12,160,526 â–¼-100.0%00.0%COMShowing largest 100 holdings. 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