Pfizer amps up push into obesity treatments with $4.9B deal for Metsera

Key Points

• Pfizer is accelerating its entry into the obesity treatment market by acquiring Metsera for $4.9 billion, offering $47.50 per share, representing a premium of over 42%.
• The acquisition could include an additional payment of $22.50 per share based on Metsera's product development outcomes.
• While Metsera currently has no products in the market, it possesses a pipeline with four programs in clinical development, potentially enhancing Pfizer's offerings in the obesity treatment sector.
• Pfizer's deal is driven by the growing demand for obesity treatments, spurred by successful products like Wegovy and Zepbound, despite the high costs of these therapies for patients.

Five months after ending development of its own obesity treatment, Pfizer is accelerating its push into the rapidly growing field with a nearly $5 billion acquisition.

The COVID-19 vaccine and treatment maker said Monday that it will pay $47.50 in cash for each share of development-stage drugmaker Metsera. That represents a premium of more than 42% to Metsera’s closing price Friday.

Pfizer also could pay an additional $22.50 per share depending on how Metsera’s product pipeline develops.

Metsera Inc. has no products on the market, but its pipeline includes four programs in clinical development and one in mid-stage testing. Pfizer said the deal will add expertise and potential oral and injectable treatments.

Pfizer CEO Albert Bourla noted in a statement from the drugmaker that there are more than 200 health conditions associated with obesity, which he called “a large and growing space.”

Demand for obesity treatments has soared in recent years, due to unprecedented weight loss provided by regular injections of market leaders Wegovy from Novo Nordisk and Eli Lilly and Co.'s Zepbound. The Lilly drug generated $5.7 billion in sales in the first half of the year.

But the drugs can cost patients hundreds of dollars a month, and experts in the field are looking for competition to potentially drive down prices.

Pfizer currently has no obesity treatments on the market but has some in clinical development. Earlier this year, the company said it was ending development of a potential once-daily pill treatment before it started late-stage testing, the biggest and most expensive phase of clinical development.

Pfizer said the boards of both New York-based companies have approved the deal, but Metsera shareholders still need to OK it. The companies expect the acquisition to close in this year's fourth quarter. It still needs approval from regulators.

Shares of Pfizer Inc. climbed 38 cents to $24.40 before markets opened Monday while Metsera's stock advanced about 61%.