NASDAQ:NEO NeoGenomics Q4 2023 Earnings Report $7.69 -0.15 (-1.91%) Closing price 05/6/2025 04:00 PM EasternExtended Trading$7.91 +0.22 (+2.86%) As of 09:22 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Earnings HistoryForecast NeoGenomics EPS ResultsActual EPS-$0.02Consensus EPS -$0.07Beat/MissBeat by +$0.05One Year Ago EPSN/ANeoGenomics Revenue ResultsActual Revenue$155.55 millionExpected Revenue$152.90 millionBeat/MissBeat by +$2.65 millionYoY Revenue GrowthN/ANeoGenomics Announcement DetailsQuarterQ4 2023Date2/20/2024TimeN/AConference Call DateTuesday, February 20, 2024Conference Call Time4:30PM ETConference Call ResourcesConference Call AudioConference Call TranscriptSlide DeckPress Release (8-K)Annual Report (10-K)Earnings HistoryCompany ProfileSlide DeckFull Screen Slide DeckPowered by NeoGenomics Q4 2023 Earnings Call TranscriptProvided by QuartrFebruary 20, 2024 ShareLink copied to clipboard.There are 18 speakers on the call. Operator00:00:00Welcome to Speaker 100:00:00the NeoGenomics 4th Quarter and Full Year 2023 Financial Results Conference Call and Webcast. At this time, all participants are in a listen only mode. Please note this call is being recorded and an audio replay will be available on the company's website. Kendra Sweeney, Vice President of Investor Relations, you may begin your conference. Speaker 200:00:22Thank you, John. Good afternoon, everyone, and welcome to the NeoGenomics 4th quarter and full year 2023 financial results call. With me today to discuss the results are Chris Smith, Chief Executive Officer and Jeff Sherman, Chief Financial Officer. Additional members of the management team are available for Q and A, including Vishal Sikri, President of Advanced Diagnostics Warren Stone, President of Clinical Services Melody Harris, President of Enterprise Operations and Ali Olivo, General Counsel and Head of Business Development. Speaker 300:00:54This call Speaker 200:00:54is being simultaneously webcast. We will be referring to a slide presentation that has been posted to the Investors tab on our website at ir. Neogenomics.com. Starting on Slide 2, during this call, we will make forward looking statements regarding our anticipated future performance. We caution you that such statements reflect our best judgment based on factors currently known to us and that actual events or results could differ materially. Speaker 200:01:20Please refer to our most recent Forms 10 ks, 10 Q and 8 ks we filed with the SEC to identify important risks and other factors that may cause our actual results to differ materially from the forward looking statements. The forward looking statements made during this call speak only as of the original date of the call, and we are under no obligation update or revise any of these statements. During this call, in order to provide greater transparency regarding our operating performance, we refer to certain non GAAP financial measures that involve adjustments to GAAP results. The non GAAP financial measures presented should not be considered an alternative to the financial measures required by GAAP, should not be considered measures of liquidity and are unlikely to be comparable to non GAAP financial measures provided by other companies. Any non GAAP financial measures referenced on this call are reconciled to the most directly comparable GAAP financial measure in a table available in the press release we issued this afternoon. Speaker 200:02:18I will now turn the call over to Chris Smith, Chief Executive Officer of NeoGenomics. Speaker 400:02:23Thanks, Kendra, and welcome, everyone. Thanks for joining us this afternoon to go through our Q4 and full year financial results. As always, I really want to begin with our mission and vision statement because it's what motivates our company and teammates on a daily basis. Our mission in Neo is to save lives by improving patient care and we just had our global sales meeting at the end of January And many of our teammates shared how cancer has impacted them or their families and how we're making a difference in their lives. It's always a great reminder of why we do what we do, and I'm so proud of the impact we're having on patients and local communities we serve. Speaker 400:02:58Now let's move to Slide 4 and get into the 4th quarter highlights. As you can see, we had another strong quarter growing revenue 12% over prior year to $156,000,000 Clinical services revenue increased 20% driven by volumes across all our modalities and another increase in revenue per test. As a highlight, NGS grew in excess of 40% and now represents over 25% of our clinical revenue. The strong growth in clinical services helped to mitigate the expected lower revenue in ADX due to a strong comparable in ADX in Q4 of 2022, as well as macro conditions in pharma sector and margin optimization initiatives that we took in 2023. From an adjusted EBITDA perspective, our progress has outpaced our internal plans. Speaker 400:03:44We achieved positive EBITDA in the Q3 of 2023 and significantly improved again this quarter. Adjusted EBITDA was up 900% as compared to Q4 last year to a positive $9,000,000 Adjusted gross profit was $73,000,000 representing a 46.7 percent margin, an improvement of 2 25 basis points compared to Q4 in 2022. Turning to Slide 5 for the full year 2023 results, revenue was up 16% versus prior year to $592,000,000 driven by penetration in the community oncology market, higher volumes, a shift to higher margin modalities and improvements in revenue cycle management. Adjusted gross profit was $264,000,000 representing adjusted gross margins of 44.7 percent and adjusted EBITDA was positive $3,000,000 for the full year, an improvement of $51,500,000 or 107% versus prior year. Now on Slide 6, I'm pleased that the Q4 continued the trend that we've seen throughout 2023 of consistent sequential improvement in revenue, adjusted gross profit and adjusted EBITDA. Speaker 400:05:04Notably, our revenue growth has been strong each quarter of the year. We've built our momentum of reaching positive adjusted EBITDA in Q3 and carried that into Q4. We believe that we've laid solid foundation for growth in 2023 and expect that momentum to continue as we move throughout 2024. Let's move on to Slide 7. As you may recall, at the beginning of the year, we laid out our 4 focus areas for 2023. Speaker 400:05:30They included profitably growing the core business, accelerating advanced diagnostics, driving value creation and enhancing our people and culture. The more time I spend in the business, the more impressed I am with our unique competitive position in the marketplace with a breadth of cancer tests, our operational capabilities and passionate teammates that lead our business every single day. We are a leader in oncology testing with significant share of patient test volume in the U. S. Our deep relationships with community pathologists and oncologists provide us an advantage in the market and our focus on oncology testing has allowed us to develop extensive patient databases and relationships and we view ourselves as a collaborative partner to pathologists, oncologists, hospitals and biopharma companies we serve. Speaker 400:06:18Beyond these market conditions, it's a strong execution by our teammates that enable us to deliver such strong quarterly and full year results to our stakeholders. Our teammates are the foundation of our company and we have strengthened our team throughout the year with key hires at all levels of the organization, including sales, lab operations, corporate functions. These new hires joined a highly talented group of individuals of varying backgrounds and experiences contribute to our distinguished culture that reflects our commitment to diversity, equity and inclusion. This afternoon, I'm going to focus on our 3 financial priorities. We continue to properly grow our core business as we execute on our commercial strategy, protect, expand and acquire, which has contributed to our strong volume growth, increased AUP and improved mix. Speaker 400:07:08Execution of this strategy enabled us to serve more than 6 100,000 patients during the year. Our continued improvement in turnaround time has contributed to or at or above market growth rates across all modalities. In addition, the mix shift towards higher value modalities in tests has supported the delivery of yet another quarterly improvement in revenue per test. Over the last 18 months, we've doubled the size of our sales force increasing coverage and penetration. We also introduced NeoAccess and NeoSeq software solutions to support providers in their clinical decisions and inform patients with upfront benefit checks as well as to identify patients who may be biomarker eligible for new therapies or a clinical trial. Speaker 400:07:50As a result of our increased coverage, clinical support and patient centric mentality, we maintained our customer experience leadership in the market with a 3 point improvement in Net Promoter Score, which is now at 70. Within our advanced diagnostic division, which includes pharma services, informatics and R and D, we continue to focus on acceleration of innovation in R and D. ADX gross margins improved 3 68 basis points over Q4 of 2022. We built a robust product development roadmap to maintain a competitive position in solid tumor therapy selection, MRD and heme, with the goal to gain market share in heme. On the R and D front, we launched 12 new or upgraded assays across heme and solid tumor in 2023. Speaker 400:08:39Within informatics, we announced a collaboration to advance heme research and AI solutions with a data set that covers over a 1000000 patient lives across more than 1,000 oncology clinics. The progress and innovation was displayed throughout the year as we presented new data at several conferences. We have focused on driving value creation from a financial perspective and we are pleased that we have delivered even further margin expansion in Q4 with efficiencies driving enhanced operating leverage. Our enterprise operation team has delivered yet another quarter progress and turnaround time, ending the year with 28% improvement over Q4 of 2022. We have now completed the consolidation of 3 international labs primarily into our Cambridge, UK location. Speaker 400:09:24Earlier this year, we kicked off our LEMS project that will bring all of our prior acquisitions that were utilizing separate LIMS systems onto one platform, which will further enable our digital transformation strategy. We have now completed the 1st phase of user requirements and expect to begin to see the benefits of Lens in the back half of twenty twenty four. Before I hand it over to Jeff, I do want to address the ongoing litigation regarding Radar. It's our policy not to comment on ongoing litigation. However, I will say that Neo is committed to serving cancer patients with MRD testing and we believe that we have several viable pathways to accomplish that. Speaker 400:10:04We've appealed the preliminary injunction of the Federal Circuit and have been granted an expedited hearing, which will occur on March 29. We intend to vigorously pursue the appeal. In addition, we have moved for an administrative stay and a stay pending appeal from the Federal Circuit Court. That briefing was completed February 20. Now let me turn the call over to Jeff to review our Q4 and full year financials in more detail. Speaker 500:10:29Jeff? Thanks, Chris, and good afternoon, everyone. I'll begin with a little more detail on our operating results for the quarter. As Chris said, we continued the year with revenue experiencing double digit growth over prior year. 4th quarter revenue was $156,000,000 a 12% increase over the prior year and a 2.4% increase from Q3 2023. Speaker 500:10:53Revenue growth was driven by growth in clinical test volume, a continuing shift to higher value tests and improvement in revenue per test driven by business mix and revenue cycle improvements. Adjusted EBITDA improved 900% from prior year to positive $9,000,000 Q4 marks the 5th consecutive quarter that adjusted EBITDA increased from prior year. We generated significant operating leverage as revenue favorability flow through to the bottom line with over 60% of revenue growth flowing to adjusted EBITDA. Looking at Slide 9, clinical services revenue of $130,000,000 was an increase of 20% year over year, driven by a 13% improvement in revenue per test and a 6% increase in volume. The growth and optimization of our sales force, along with the effective execution of the commercial strategy, resulted in higher volume growth. Speaker 500:11:50Turning to Slide 10, average revenue per clinical test increased by 13% over prior year to 4 $41 representing an improvement for the 11th consecutive quarter versus prior year as we maintain focus on higher value tests and revenue cycle management initiatives. As we shared with you in the past, NGS is a strategic priority accounts for over 25% of our total clinical revenue for the year. New NGS portfolio additions and the focused effort of our sales team continue to fuel accelerated NGS growth. Turning to Slide 11. As we forecasted on prior quarterly calls, Advanced Diagnostics revenue declined 17% over the prior year in Q4, but was up 5% sequentially to $26,000,000 ADX revenue did grow each of the 1st 3 quarters of 2023 versus 2022. Speaker 500:12:46However, Q4 of 2022 was an unusually strong ADX quarter with revenue growth of over 40% versus prior year. The expected decline in revenue was partially due to macroeconomic conditions and pharma R and D spend as well as our decision to rationalize our global testing sites and low margin contracts. The focus on profitability and margin growth is driving performance in ADX with adjusted gross margins expanding by 3 68 basis points versus the prior year. Similar to our clinical strategy in 2023, we are expanding our ADX sales organization in 2024 to further accelerate profitable growth and expect to see benefits from this initiative as the year progresses. Looking at the income statement on Slide 12, adjusted gross profit increased 17.8% over prior year and adjusted gross margin was 46.7 percent, an improvement of 2 25 basis points over the Q4 of last year. Speaker 500:13:49Adjusted EBITDA was positive $9,000,000 $11,000,000 or 900% improvement versus prior year. These significant improvements were driven by both higher gross profit and disciplined cost management, which highlight the operating leverage in the business. Regarding operational expenses, sales and marketing expense was $18,100,000 as we continue to increase our commercial investment, G and A was $59,800,000 and R and D expense was $7,100,000 Turning to the balance sheet on Slide 13, we ended the 4th quarter with cash and marketable securities of $415,000,000 We continue to make good progress in diligently managing our cash and are focused on accountability and disciplined oversight of operating expenses. Cash flow from operations was a positive $18,000,000 in the quarter, an improvement of $21,500,000 or 5.83 percent from Q4 of 2022. Now let's review our full year 2023 financial results. Speaker 500:14:53Starting on Slide 15, for the year, we increased revenue by 16% over prior year, driven by increases in test volume, revenue per test and NGS revenue in clinical services. Adjusted gross profit increased by 27.5 percent to $264,000,000 as a result of higher revenue and effective cost management. Adjusted EBITDA improved $51,500,000 versus prior year due to improvements in revenue and gross profit. Looking at the balance sheet on Slide 16, we ended the year with cash and marketable securities of 415,000,000 dollars Cash flow from operations improved $64,000,000 or 97% from 2022. This strong performance in reducing our cash burn provides us with multiple avenues to address our upcoming convertible notes due in 2025. Speaker 500:15:45We expect to provide more clarity on our near term maturities on our Q1 2024 financial results call. Now turning to our 2024 outlook. We continue to see strong revenue growth and an increase in NGS product mix and are very encouraged by our new and updated tests, which provide higher operating leverage to the bottom line. We have made the necessary and appropriate investments in our teammates to ensure that we have a world class group of people who are aligned with our mission of serving patients and saving lives. As we continue to build this business brick by brick, I am more confident in our future than ever. Speaker 500:16:26Moving on to Slide 18, for the full year 2024, we expect revenues of $650,000,000 to $660,000,000 representing 10% to 12% growth and adjusted EBITDA to be in a range of $21,000,000 to $24,000,000 representing 600% to 700% growth. In summary, 2023 represented a strong year of execution and financial performance, which positions us well to continue the momentum in 2024. We will continue to invest in growth initiatives, including investments in sales force optimization and expansion in our clinical and ADX businesses and increasing investments in R and D, product and business model innovation to further enhance our menu of tests. In addition, we will be making targeted investments in operating efficiencies, including automation and consolidating our multiple LEMS systems into one consolidated platform over the next 24 months. These investments will drive long term margin growth in the future and are reflected in our annual adjusted EBITDA guidance range. Speaker 500:17:36Based on our cost structure, the revenue growth in 2024 will drive operating leverage and our adjusted EBITDA growth will exceed our revenue growth. We anticipate seasonality of our business to be reflected in each quarter of 2024. Therefore, we expect revenue to be down sequentially in Q1 2024 in a range of $148,000,000 to $151,000,000 representing 8% to 10% growth over prior year and expect our strategic initiatives to drive a higher growth rate as the year progresses. Based on our strong performance in 2023 and our confidence in our strategic initiatives in 2024 and beyond, we are increasing our long range revenue growth target in outlying years from 7% to 9% to 10% plus in our core business excluding MRD. Speaker 400:18:31Thanks, Jeff. I'm very proud of our team's Q4 and full year progress, including strong revenue growth of 16% for 2023 and significant improvement in adjusted EBITDA and cash flow from operations. We saw meaningful progress in the execution on our strategic priorities and therefore we're able to reach the high end of our raised guidance. Our guidance for 2024 and beyond reflects our confidence in our business. We believe we're well on our way to becoming the leading cancer testing information and decision support company. Speaker 400:19:02We will continue to build on the foundation we have laid over the past several quarters to deliver long term sustainable growth. I'm excited for our teammates and our customers and most of all for the patients we serve on a daily basis. Thanks for taking time to connect with us today. I'll throw it back to the operator. Speaker 100:19:20Thank you. At this point, we will open the line for questions. The company asks that each person limit their questions to 1 so that we may hear from everyone within the hour allotted for this call. Okay. And the first question comes from Alex Nowak with Craig Hallum. Speaker 100:20:10Please proceed. Speaker 600:20:11Okay. Great. Good afternoon, everyone. Hey, congrats on the results. I'm sure the potential of FDA coming out and issuing final rules. Speaker 600:20:28Depending on the definition of an LDT, NEO could have a wide variety in its portfolio. Speaker 400:20:33So I'm just curious what you've talked a little bit in the past, but what is Speaker 600:20:37the team internally doing now just in case the FDA does decide, hey, we're going to move forward and issue a final rule? Speaker 400:20:44Yes. Thanks for that. Look, I mean, obviously, we like other companies in our sector are watching that closely. We're on the ACLA board and so I think we've seen it coming. Look, I would say a couple of things. Speaker 400:20:56I would say our progress or our focus on this started probably 18 months ago when we came together as a management team. We started bringing in people who come from regulated backgrounds. So if you think about like the folks on this call, the 3 division presidents, myself, Jeff, all of us come from FDA regulated backgrounds. I think we started to build the quality system that way. We move to one quality system. Speaker 400:21:18We took all the acquisitions and moved them to 1. All of our R and D projects are now under design control. So we've kind of been starting to operate believing this is coming. That being said, there's still a lot to unfold. Once a ruling comes out, I think there's a lot of people in the industry who wonders if it's constitutional. Speaker 400:21:38But from our perspective, we think it's probably not if it's probably when. And it looks like even if all these things could occur, companies are going to have 3 to 3.5 years to get prepared. So we feel very confident in our ability to manage that as it comes on. Look, a lot will depend on what is grandfathered and what is not, but I think we feel really good about our position in the marketplace. And we think for companies like us, it could be end up becoming a competitive advantage. Speaker 400:22:06All right. Thank you so much. Speaker 100:22:09The next question comes from David Westenberg with Piper Sandler. Please proceed. Speaker 500:22:14Hi, David. Hi, David. Thank you. Speaker 700:22:15Hey, great job guys. So I really like the update on the if I heard it right, you updated the long term plan to 10% growth. Can you talk about specifically, because that's a big 150 basis points at least swing there. So what specifically is happening versus that long term growth plan? Where you feel confident that this is not just trend, this is multi year and long term? Speaker 700:22:41And that's assuming I heard that correctly. Speaker 400:22:44Yes, you did. I mean, Jeff put it in there at the end. It's like some of the best news and it was like right at the end. I'll say something and then maybe I'll have Jeff comment more. But look, I think when we gave long term guidance in April of last year, we were pretty new management team. Speaker 400:22:58And I think as we've come together and now had well over a year under our belts, we understand the levers to pull in the business much better. We understand the market significantly better. We understand things around revenue cycle management and accelerated growth and where the gaps are in the products. And so we guided this year for 24% 10% to 12%. But what we're seeing in that core business just because of the market dynamics, the market growth, our leadership position, the things that we can do, we feel very confident in that 10% plus number. Speaker 400:23:28But do you want to? Speaker 500:23:29Yes. I would add to that. We've made multiple comments about adding sales force people to our team and then sales force optimization, we're really focused on how do we help them be more efficient. And so we actually think we can get a lot of operating leverage just through technology and back office support for our sales people, both in our clinical team and in our ADX team. And so I think that's another big component. Speaker 500:23:56We've been growing faster than the market across all modalities. We have a strong focus on NGS and are clearly seeing positive results there. So I think our view is our confidence level has increased based upon our performance in 2023 as well as, as Chris said, the team overall just getting more comfortable with our teams, with our position in the market and where we're investing dollars to raise our long term growth target to that 10% plus. Speaker 400:24:26Yes. And David, I'd say the other one. I mean, if you look at NGS, especially solid tumor, we're incredibly under indexed and you can see that business is growing rapidly. And that market is still relatively penetrated, but growing double digits. So I think there are a lot of factors that we feel really good about where we are from a position perspective. Speaker 700:24:43Great. That's a great segment and a second one because I think you're launching into liquid. So could we expect an accelerated timeline into liquid or like a market traction just given what you're doing right now in hematological malignancies and then you transfer that into solid tumor, which has been going really fast. Speaker 400:25:05Let me let you know obviously a lot going on, but that sits in kind of the R and D group with Vishal and under development. Vishal, do you have anything you want to share just kind of what we're doing with liquid and some of the products that we've disclosed? Speaker 800:25:16Yes, David, thanks for your question. So on the liquid side, we will plan to launch CGP assay for liquid biopsy going into 2024, probably towards the second half of twenty twenty four, but we'll accelerate on the clinical side also that we're looking into. But I do think there is a place for liquid in both the pharma and the clinical side, which we'll see an acceleration in terms of penetration into that market, especially on the pharma side in particular, because we're hearing a lot from pharma companies that they just don't have enough tissue to spread along with all the testing they want to do. So this really gives them the opportunity to choose both liquid or solid from that perspective. Speaker 400:25:55Yes. And you'll probably see that in pharma in late half of the year and then moving into clinical in 2025 early 2020. Speaker 700:26:05Awesome. Great job in the quarter. Speaker 500:26:08Thank you, David. Speaker 100:26:09Up next, we have Puneet Souda with Lyric Partners. Please proceed. Speaker 900:26:14Hey, guys. Chris, Jeff, thanks for taking the questions. How are you doing? I'm good. Thanks, Chris. Speaker 900:26:22I'll wrap my question into 2 questions sort of into 1. Obviously, again, congrats on the LRP increase here. Maybe can you elaborate what is the clinical volume growth that we ought to think about in that sort of long term guide? I mean, at one point, NeoGenomics used to grow that number at 15% growth, but I know the mix has changed today. There's more NGS in here. Speaker 900:26:54So maybe could you elaborate on that? And then how should we think about the AUP and the clinical volume growth this year in 2024? The AUP has continued to ramp throughout the year for clinical in 2023. So just wondering sort of how should we think about that for 2024? Thank you. Speaker 1000:27:12Yes. Maybe I'll take Speaker 400:27:14a little bit of that and throw it to Jeff. But look, the way we think about our business is really portfolio effect. And so if you think about it, we really we have informatics, we have pharma, we have clinical. And obviously, when we look at building out both this year's guidance and next outline year's guidance, we've taken into account all those factors. We have not broken down specifically the units or the AUP. Speaker 400:27:38I will say though on the AUP, 2 things significantly are driving and Jeff will give you more, but one is our mix, right? We're selling a lot more NGS. But the other thing is, we think we have a lot of runway on revenue cycle. And just the amount of when you look at this industry as a whole, I think it's woeful in its ability to get paid for the work that it's doing. And I think where our team is really becoming masterful is identifying those levers, which is probably 15 different levers within that group. Speaker 400:28:05But Jeff, do you have anything else more on what Yes, I think, Speaker 500:28:08I mean, we haven't disclosed specific and we didn't when we gave original guidance, didn't disclose volume or AUP. But I think, as Chris said, given our positioning on both our clinical sales force and revenue I think on the revenue per test or AUP, as Chris said, there's a few things driving that. In the quarter, that NGS mix, I said this last quarter, is driving over 60% of the increase in AUP. So just the NGS volume continue to accelerate is driving meaningful upside in revenue per test. And you can see that stepping up throughout the year in 2023. Speaker 500:28:55And then the other factors, as Chris also said, were revenue cycle specific initiatives. The first is on just getting paid for the work we're doing, a lot of specific initiatives to drive that. We saw good improvement in that in 2023. And then there's also the pricing side where we're having some success in getting price increases as well, where that hasn't historically been a strength of ours. So, as well, where that hasn't historically been a strength of ours. Speaker 500:29:18So again, I think the way I think about the revenue side is we have volume drivers, we have mix drivers, we have pricing drivers and we have RCM drivers and they're going to hit at different intervals and different paces throughout the year. But the overall combination of those is going to get us to our revenue growth over time. Got it. Helpful, guys. Thank you. Speaker 1000:29:41Thank you. Speaker 100:29:42Okay. The next question comes from Matt Sykes with Goldman Sachs. Please proceed. Speaker 1000:29:47Hey, Matt. Speaker 1100:29:47Hey, good afternoon. Hey, guys. How are you doing? Congrats on the quarter. Maybe just following up on Puneet's question, but focusing on the mix side of it. Speaker 1100:29:56Obviously, the NGS mix you guys have talked about and that's driving a lot of that. But I'm just wondering in terms of like as you think about the runway for mix shift, there's clearly probably customer groups where it was easier to kind of switch them into NGS or market the NGS to them. Does mix shift get harder you think over the course of this year and into 2025? Or do you just see a lot of runway and lack of awareness where you're able to continue to drive that mix shift over time? And then just my second part, just quick one for Jeff. Speaker 1100:30:24Just any views on the gross margin outlook for 2024 within that guide? Speaker 400:30:29Yes. Thanks, Matt. Look, I think when you look at this business, one of the things that we really like as we've gotten to know the business well is that we're very under indexed both on NGS as the total percentage of revenue for the company as well as in solid tumor. And do you think there's going to be some earning calls that come up in 90% of the revenue is NGS. And so I think we believe very strongly I think in that ability on that mix shift. Speaker 400:30:52I'd say the second big one is, I think you could argue this year should be better because of our increased focus going to oncology, community oncologists versus just the hospitals and the pathologists and expanding that sales force there and to be able to go out and spend time. Look, one of our lever points is that we're the market leader in heat and really using that to be a door opener for us for Solid. But maybe I probably shouldn't even say as much as I did Warren's here, but maybe Warren give more maybe more color. Operator00:31:23Yes. Chris, Speaker 1000:31:23I think everything you just said, I agree with 100%. I mean, we've communicated that right now the ratio is roughly 25% of the business. I think as that ratio increases, certainly it gets marginally harder. But I wouldn't discount the fact that we have launched new products last year. It was probably mid year by the time we were starting to see some traction take place. Speaker 1000:31:43So looking to benefit from the annualization of those new products that were launched in last year, particularly those are NGS related. So that's one that certainly will provide opportunity for us. And then as Chris said, the continued penetration into the community oncology segment, which is where we've invested a lot of incremental sales resources into is another reason why we believe we can drive growth in NGS, which will support that mix shift. Operator00:32:09Jeff, do you want to take that? Speaker 500:32:10Yes. Then on the margin side, Matt, I would look at adjusted gross margins increasing in a range of 150 basis points to 175 basis points over the next year over 2024. Great. Operator00:32:25Thanks guys. Speaker 100:32:26Thank you. Next we have Andrew Breckman with William Blair. Andrew, please proceed. Operator00:32:33Hi, guys. Good afternoon. Hey, Chris. Thanks for taking the questions. Maybe on the inorganic front, I guess as you guys are making progress here on increasing profitability, can you just sort of talk about balancing that dynamic with your sort of appetite for adding to the bag here over time? Operator00:32:48Any considerations that we should sort of be thinking about? Thanks. Speaker 400:32:51Yes. Andrew, I got to tell you, I missed the very first thing you said. What? No. Inorganic growth. Speaker 400:32:57Okay. Sorry, I missed that. Yes, look, I think it's a unique scenario when a company looks at accelerating growth and how much do you put on the bottom line versus how much do you invest. We believe that this business has a very unique opportunity to grow low double digits on revenue and mid teens plus on profitability. I think for us, we look at where we can invest the dollars that we think are going to give a long term ROI. Speaker 400:33:25So we spend a lot of time as a leadership team talking about what these initiatives are and when are we going to strategically invest in them. So for example, this year, one of the big ones is LEMS. Last year, a big one was expanding the clinical sales force. So we believe that you can have that balance. Like Jeff always says, it's not either or, it's and. Speaker 400:33:43And I think our view is that we want to grow revenue fast, gross margins faster and operating profit fastest. And I think we run our business to do that. So I think we feel really good about that balance. But Jeff, do you want to get from a financial perspective? Yes. Speaker 500:33:57I think the other thing that gives us confidence is just our capital structure as well and our ability to really significantly change our cash burn and actually position ourselves for actually starting to produce cash in 20 25. So I think having the clear path to being adjusted EBITDA positive for all of 2023 and certainly we expect effort for 2024. And then really it's an investment, I think, rigor and discipline that we have used over the last 12 months, where are we going to be investing dollars and how are we doing that in a strategic fashion over time to drive the business. And I think as Chris said, clearly with having ROI projects that are going to pay for themselves over time. And I just think we've had a lot more rigor and discipline in the process, which gives us confidence in the investments we've made. Operator00:34:57Okay. Thanks guys. Speaker 100:35:00Up next, we have Mark Massaro with BTIG. Please proceed. Speaker 800:35:04Hey, Mark. Speaker 1200:35:06Hey Chris, how's it going? Speaker 400:35:08Good. Speaker 1200:35:10Yes, congrats on the quarter. Lots of great progress on the clinical side. I guess my question is more on pharma services. I know your predecessors talked a lot about pharma services and informatics And there is a large precision oncology company out there that's monetizing big data with some pretty sizable revenue. So I'm just curious like you guys are doing a great job just growing revenue and profitability. Speaker 1200:35:41Maybe just give us an update on how you see the pharma services business shaping out? How you can monetize some of the big data? And maybe just give us a sense for how you're thinking about the growth of that business going forward? Speaker 400:35:55Yes, thanks. Look, I think when we came in, I mean, I think the first thing is we made a very conscious decision that that business had a lot of pieces to it that were not profitable. And so our focus was and we've talked about this in the whole company, but especially in pharma, let's get the house in order. And let's get this gross margin moving and you can see that we've made great progress in there. I think when we think about the pharma business, so we do believe it's kind of the tip of the spear from a technology perspective because the pharma companies go well in front of clinical on new innovations and new technology. Speaker 400:36:29And we saw that, for example, in MRD. So we believe it's a place to be. But before we could start accelerating growth, we had to get the baseline right. And that's what 2023 was all about. And now you heard that, Jeff, one of our last year, we spent a lot of money and time expanding the clinical sales force. Speaker 400:36:44We're expanding now the pharma and the informatics sales force because we feel like there's great growth opportunities there, but we felt like we had to direct kind of right to shift first. On informatics, we have significant points of data because of our the patients that we test. And I think as Vishal and I'll let Vishal step in and maybe talk more about the informatics. But I think as Vishal and Melody come together and kind of look at the things that we can do, there is runway, but there's a lot of work to do. And I think that the company you're probably referring to, it was not our top priority, but it's becoming more of a priority. Speaker 400:37:17But I think for us, again, it's about the portfolio. We got to be able to perform in clinical and all of ADX. Do you want to talk more about specialty informatics and the data? Speaker 800:37:27Yes. I think as we look at the data that we have within the company, one of the nice things about what NEO has is data across all of our modalities whereas others maybe will have it primarily in NGS. But as we grow our NGS product portfolio, our data will also grow at the same time. So what we can get to in a couple of years is going to be much different than where we are today in terms of our data offerings as a whole. And on top of that, the LEMS investment that we're doing, which will allow us to structure the data in the right way, will also make us successful for the informatics side. Speaker 800:37:58So altogether, the next couple of years, we still have a long way to go there. I mean, I think we have to build in the right steps. But how we're building it is more important right now for the next year and getting 2 years out as to what we can do with that data from where we are today. Speaker 1200:38:15Sounds good. Congrats on the progress. Speaker 500:38:17Thanks Mark. Speaker 100:38:19The next question comes from Mike Matson with Needham and Company. Please proceed. Speaker 600:38:24Hi, Mike. Hi, guys. Just wanted to ask one on the LIMS project. So you mentioned you could start to see some of Operator00:38:33the benefits of that in Speaker 600:38:34the second half. So So just curious what those benefits could be? I mean, is it margins? Is it per turnaround time? Is it market share or all of the above? Speaker 400:38:47Yes. Look, I think there's a lot. It's probably all of the above. And Melody is on the call as well. Melody, do you want to take that initially and then Jeff maybe could talk about financial stuff with Melody? Speaker 300:38:58Sure. I think first and foremost, Mike, it's really around operational efficiency and productivity in the lab. So I think we're going to we're expecting to see a lot of pickup with regard to leverage there because we currently are on multiple different systems. And obviously, that causes a lot of cutting and pacing and things like that, that we're hoping to eliminate. But as far as then, Vishal mentioned the ability to use our data better, it's really an overall enterprise digital architecture that we're working and wins is the start of that. Speaker 300:39:36But we're also leveraging various platforms for better connectivity to our patients, better connectivity to EMR, better connectivity into our billing systems and our back end ERP. And the LIMS system is really the big driver for all of that for us. Jeff, comments on the cost structure? Speaker 500:39:58Yes. And I would add one other thing as well. I mean, it will give us just better visibility from client service perspective on where our tests are in the process and allow for really self-service on where tests are in the process. So I think it helps our client communication and giving them up to date on where we are with the testing process. And then we are making capital investments that will have some operating expenses with that over the next 2 years. Speaker 500:40:26So we have factored in those operating expenses into our guidance. And again, I think this is one of those investments that is going to pay long term dividends. We'll start seeing it on the gross margin side as Melanie noted from an efficiency standpoint. And I think over time, it could have top side benefits as well as we improve our client service. Speaker 400:40:47Yes. And maybe Warren, you can talk to this, but look, we're spending probably as much on the customer experience component Speaker 800:40:54as we Speaker 400:40:54are on the lens as far as digitization. And it's interesting, I think in this business for us to ultimately get to where we want to go, we got to win on customer experience and we got to win on the ability to serve the patient. And I think you want to just give what we're doing on the digitization and the platform. Yes. That's going to tie to limb. Speaker 1000:41:13Yes. Building on what Meny said in terms of Lens being the sort of foundational element for us to start a digital transformation, this is providing the building blocks for us. And additionally, we're investing in what we're calling a digital front door to our customers, which will be the platform for self-service. It will be the platform to allow customers to track the status of testing in real time, something that is certainly missing today. And ultimately, it will allow us to increase stickiness to those customers, which is an important element from our protect, expand, acquire commercial strategy. Speaker 1000:41:49So something else that we look to expect to see value in the latter part of 2024. Thanks. Speaker 600:41:56Great. Thanks. Speaker 100:42:02Okay. Your next question comes from Mason Carrico with Stephens Inc. Please proceed. Speaker 500:42:07Hey, Mason. Hey, guys. Speaker 1300:42:10Thanks for the question here. So for the ADX business, you had called out, you framed it up in previous quarters, these the headwinds that you'd be facing, rationalizing some testing sites, low margin business as well as you're facing some macro conditions. So I guess the question is, could you kind of break out, I guess, how much of an impact each of those 2 buckets have? And as we look ahead into this year, when do you think we start to lap kind of rationalizing that low margin business going forward? And really how are you thinking about accelerating growth in this business this year? Speaker 400:42:51Yes. Why don't I take it upfront and then Vishal can pick it up. I mean, we made that decision, but those contracts took some time. So I think you'll start to see that piece start to kick in probably in the second half of the year. We haven't broken out where the impact is. Speaker 400:43:07But I think even more importantly, Vishan, maybe talk about strategically all the things that your team is doing in other modalities just NGS and why that's still relatively new and why you give confidence in the acceleration of the growth? Speaker 800:43:19Yes. If you look at what pharma is coming up to us for, right, we are still investing heavily in modalities, what I call our traditional modalities like IAC. That's not going anywhere from an oncology pharma perspective. That's our bread and butter. But as we launch new products in the NGS side in particular, and we're seeing that trend. Speaker 800:43:41And as Chris mentioned, usually what we see in pharma is a movement and moving towards technologies 3 to 5 years ahead of clinical. We're already seeing that trend moving from FISH as an example to NGS. We didn't have the right products until we launched them last year. So we're starting to see that movement into more and more usage cases in NGS, which also have higher AUPs for that matter. So we're also investing in our BD team. Speaker 800:44:07We invested a lot in the clinical side from a sales perspective. We're investing now on the ADX side and rebuilding that BD team and making sure that we have the tools and expertise that will allow us to grow in 2024. Speaker 400:44:19Maybe talk about liquid biopsy because that's going to be a big product Speaker 900:44:22for you guys. Speaker 800:44:23Yes. Liquid biopsy is something that we get approached by from pharma all the time is we do a lot of tissue testing right now, which is what we've built our business on. But on the liquid side, especially for solid tumor and as Chris mentioned earlier, we're very much under penetrated on the solid tumor side because we didn't have the right product mix. And now we're launching our liquid bio XCGP, which will allow us to make that offering to pharma where they don't have tissue to give to us for samples that have been sitting around 3, 5 years to 10 years old from clinical trials that have been completed. So we're able to go back and actually try and get some of that business with our new offering that we're planning to launch this year. Speaker 500:45:03That's helpful. Thanks guys. Operator00:45:05You too. Speaker 100:45:07Up next, we have Andrew Cooper with Raymond James. Please proceed. Speaker 400:45:11Hey, Andrew. Speaker 1400:45:12Hey, guys. Thanks for the time. Maybe just first focusing on price for a little bit here or AUP, I should say. Can you just give a sense for how much more runway is there in that 40 percent of the increase that's come from RCM and price? Or maybe ask another way, what can we expect that to contribute on a yearly basis once mix is stabilized or in the scenario where kind of on an apples to apples basis we think about mix being stabilized? Speaker 1000:45:41Yes. Speaker 500:45:44Without kind of getting into granular specifics, we said earlier NGS was driving about 60%. We are still seeing mix improvement in other aspects of the business, which is driving a component of AUP or revenue per test as well. I think in terms of the initiatives, we think pricing is a multi year opportunity for us. And we also think the revenue cycle initiatives that are just increasing the amounts where we're getting paid for what we expect to be paid is a multiyear opportunity. So I think we have multiple year opportunity to continue to close the gap between what we're expected to be paid and what we are being paid. Speaker 500:46:29And again, as I've said in prior calls, it is multifaceted. I mean, there are some other clearly identifiable areas of prior authorizations or medical necessity or medical records that we're dealing with. And then there's the payer policy aspects, which are a little bit harder, particularly with the larger panel tests. And so as some of the biomarker legislation gets approved gets approved in states over time, that will also help close the gap for specific tests where we may not be getting reimbursed today or where we're not being reimbursed fully. So again, I think there's a lot of different areas that we've identified that we have teams working on to close that gap and see a multiyear runway. Speaker 1400:47:14Okay, great. And then maybe just one more. On the LRP update, obviously, great to see. Maybe just any context for what that does or doesn't do to the EBITDA margin expectations that you laid out back in April and whether that number can be a little bit higher for 26% or maybe how we think about even beyond that timeframe where adjusted EBITDA margins might go in the event of kind of that little bit faster revenue growth? Speaker 500:47:41Yes. So what we said almost a year ago was we expected EBITDA margins to be in the mid to high teens by 2027. Obviously, going towards the higher end of going to above the high end of that range, I think will help accelerate that. I don't know that it changes meaningfully when we achieve that mid to high teens, but it could pull it forward, I think, a period of time. And also just our ability to generate operating leverage off that revenue growth, I think will help the adjusted adjusted EBITDA growth over time as well. Speaker 500:48:21We initially said we expected to be adjusted EBITDA positive in 2024. Obviously, we achieved that in 2023. So again, almost probably pulling forward somewhat a year on that front. So I think as we look at our ability to generate operating leverage on the revenue growth, it clearly will benefit our long range plan from an adjusted EBITDA and adjusted gross margin basis. Speaker 400:48:45Yes, Andrew, I think as we like I talked about earlier, as we've seen the levers and the ability pull multiple ones to get leverage and pull through on this business. You saw this year the significant amount of our growth drop into the bottom line. And so I think that we that's enhanced kind of our confidence in some of these things. Now we still have things like value capture program where we want to go get anywhere from $10,000,000 to $15,000,000 a year. We want to improve gross margins and get gross margin leverage by 100 basis points every half. Speaker 400:49:15I mean, all those are fundamental. But I think now, like when you think about Melody, on her side on the operations, she now has the detailed plans in place and we can see that. So I think it just has given us a greater sense of confidence in our ability to deliver it. Speaker 1400:49:29Great. I'll stop there. Thanks again, guys. Speaker 500:49:32Thanks. The Speaker 100:49:34next question comes from Derik De Bruin with Bank of America. Derik, please proceed. Speaker 500:49:39Hey Derik. Speaker 1500:49:41Hey, good afternoon. You have John Kim for Derek here. I'm going to try to ask this one more time. Great to hear the 2024 guide and update on the long term guide here. Any other details that you could share on what the split is going to be between the clinical services and advanced diagnostics? Speaker 1500:50:06I think you previously talked about how the clinical services would be a bigger portion of the sales, but yes, would be helpful to know any additional thoughts that you might have? Speaker 500:50:17Yes. We have as Chris said earlier, we really view it as an overall portfolio and we guide on a portfolio basis. So we haven't broken out that individually. We do expect both of them to grow in the year. We just haven't broken it out and don't plan on breaking out in our guidance. Speaker 1500:50:37Got you. And I did want to ask about the patent infringement ruling against radar that was in December. Any expectations as to I know it's not included in the guidance, so not expecting any financial impact there on the top line or the bottom line. But any expectations in terms of when you think this might get resolved or like if it comes to getting rid of it, what impact that could have on the bottom line? Speaker 400:51:13Yes, I'm going to let Ali address the legal questions, but two quick points. So our guide does not include any radar in it, number 1. But number 2, we do believe MRD is important. So I'll just put that and then I'll throw it to Ali to let her kind of walk through how the legal side is going. Operator00:51:29Sure. Speaker 1600:51:30We don't have any visibility to the timing. What we know is that we've requested an expedited hearing and we've been granted that expedition and the hearing was, as Chris said, on March is scheduled for March 29. And so various factors kind of contribute to the Federal Circuit Court of Appeals timing on a decision, including whether or not the decision is precedential, whether there's a dissenting opinion on the panel of 3 judges. We have also made a motion for a stay pending the appeal. And that motion was fully briefed, like Chris said, as of today. Speaker 1600:52:10And so timing on that is within a couple of weeks. That's sort of what we know in terms of timing on the appeal. As far as the infringement matters in district court, those are ongoing and are in Speaker 400:52:26the discovery stage. The North Carolina case has been Speaker 1600:52:26set for trial in 25. Speaker 200:52:35Appreciate all the Speaker 100:52:47Up next, we have Tejas Savat with Morgan Stanley. Please proceed. Speaker 1700:52:52Hey, guys. Good evening. Sajid, I just wanted to push on that similar line of questioning there. I was curious, Chris, in terms of the comments you made in your prepared remarks about your options available here, right? Can you give us a sense for how quickly you could pivot to perhaps a new version of Radar as a workaround for the litigation? Speaker 1700:53:17And that's something we've seen other peers in the industry resort to in relatively short order. And I was curious if that Speaker 400:53:26was an option that you were actively Speaker 1700:53:26exploring at the moment as well. Speaker 400:53:32Tejas, thanks. Look, I would say that we're actively exploring all options around MRD with the first situation that we believe, vinaciously about our position from a legal. So I mean, obviously, that's where we're going. That being said, we have been in development for additional MRD products beginning probably 12 months before this even started. So I would say that that's been ongoing. Speaker 400:53:56And I would say with us, we believe like a lot of the products that we're trying to bring to market, we think there's an incredible need from a patient perspective, especially for products that continue to improve sensitivity. And I would say that Vishal and the team in R and D operate with an incredible sense of urgency. But it's not just from a technology perspective, but it's from an IT perspective that they're looking at us from a commercialization perspective. But we haven't given any timelines just that we're operating with a sense of urgency on it. Speaker 1700:54:28Got it. Fair enough. And then just one quick follow-up for me on the biomarker bill. Can you lay out, Chris, what proportion of your tests you think could benefit from incremental commercial payer coverage here, given even the states that have currently passed the legislation? Speaker 1000:54:47I don't think so very clearly, where we believe the value will come is on any NGS test, which is a panel of 50 or larger gene. That's where today reimbursement from a 3rd party payer perspective is quite limited. So that's where we see the benefit. In terms of I think what portion of our business that is etcetera, that's something we actually haven't commented on. Speaker 400:55:10And one of the things we'll talk more about some of the strategic priorities in 24 when we get together after Q1. But one of them is to launch our Neo comprehensive 2.0, which is a significant larger panel. And so obviously that will be an important tool for us. Speaker 1700:55:27Got it. That's helpful. Appreciate the time guys. Speaker 500:55:30All right. Thanks. Thanks. Take care. Speaker 100:55:33The next question comes from Dan Brennan with TD Cowen. Please proceed. Speaker 400:55:37Hey, Dan. Operator00:55:38Hey, thanks for hey, good morning, Chris or good afternoon, excuse me. Maybe just a question back to the liquid offering. Any color on what type of reimbursement we can expect? And how should we think about framing the opportunity from like a revenue potential perspective? Speaker 400:55:55You want to take that? Talk a little bit about what's going on in the market? Speaker 800:55:59Yes. So the good news here is that, I mean, there is reimbursement that's established similar to what you see with the tissue test. And we expect something from a reimbursement perspective, at least for Medicare, would be in the similar type dollar amount as what we see on the tissue side of things with potential for higher depending on what kind of status we get on this. But the reality is that we're also seeing NCCN guidelines get tissue or liquid being done at the same time or independent of each other. So I think you're seeing the guidelines are changing and that also helps with the whole reimbursement story and the clinical adoption of course, especially in the community based setting. Speaker 800:56:55So I think having a liquid offering that is widespread is going to be critical for us for commercial growth. Operator00:57:03Great. And then maybe just sticking with NGS, clinical market volumes probably growing north of 30. Just wondering, for your volume growth, how much if we're thinking about like the market growth versus converting your customers from, say, legacy test to NGS, Could you just give us a sense of like maybe I know you're not going to distill the exact numbers for each, but I'm just wondering how far along your customers are and is that a big driver for you that you're kind of bringing forward some of these more community hospitals and doctors towards MGS? Thank you. Speaker 400:57:37Yes. I'll let Warren take it. But remember, we have 3 distinct strategies that we focus on and really from a field compensation perspective, they're incentivized on all of them. Do you want to talk a little bit about what's going on? Yes. Speaker 400:57:48I think there's a Speaker 1000:57:48couple of dynamics that are taking place. Certainly, we've got customers that may not be using NGS today using a different modality that we're moving into NGS. That's the first kind of motion. 2nd is we have a number of smaller gene single gene and smaller panels that are available and these we're moving customers to larger panels. And then obviously, we have the dynamic of customers which haven't been near customers in the past that are now we're now addressing and this is particularly relevant in the community oncology setting. Speaker 1000:58:21So those are kind of the 3 kind of areas where we see sort of growth from an NGS perspective. And it really plays into with our commercial strategy, which again it's around protecting existing customers, but secondly expanding share of wallet where we drive various sort of GAAP analysis strategy to identify which customers to target with different NGS offerings, which could be one of those 3, not using NGS moving to NGS or using a single or small panel into a larger panel. And then thirdly, it's the acquire element of our commercial strategy, which is gaining customers, which haven't been supportive of NIO in the past. Speaker 400:59:01And that third one is obviously the toughest, getting new customers, but it's by far the biggest opportunity where we just hadn't been spending time till starting about 12 months ago, which is those community oncologists. Speaker 500:59:12Great. Thank you. Speaker 400:59:14Thank you. Speaker 100:59:16We have reached the end of the question and answer session. And I will now turn the call over to Chris Smith for closing remarks. Speaker 400:59:23Okay. Thank you. Look, I just appreciate everybody taking the time to get together and get some more color on what's going on inside the business. We kind of talked about the state of the business. And I think we feel incredibly good about where the business is and where the business is heading. Speaker 400:59:39I think we're ahead of where we thought the early plans are being. And I think as we continue to go forward each quarter, we'll try to give you more insight into the business and how we continue to build this long term sustainable growth. Again, thanks for your time today and take care.Read morePowered by Conference Call Audio Live Call not available Earnings Conference CallNeoGenomics Q4 202300:00 / 00:00Speed:1x1.25x1.5x2x Earnings DocumentsSlide DeckPress Release(8-K)Annual report(10-K) NeoGenomics Earnings Headlines3NEO : Assessing NeoGenomics: Insights From 9 Financial AnalystsMay 7 at 2:12 AM | benzinga.comBrokerages Set NeoGenomics, Inc. (NASDAQ:NEO) Target Price at $19.30May 4 at 3:01 AM | americanbankingnews.comTrump wipes out trillions overnight…Is there anybody more powerful than Donald Trump right now? In a single tariff announcement, he wiped out nearly $5 trillion in wealth from the S&P 500 and $6.4 trillion from the Dow Jones… Not to mention the countless trillions of dollars lost in every market around the world… leaving the major political powers scrambling in fear of Trump’s next move.May 7, 2025 | Porter & Company (Ad)NeoGenomics, Inc (NEO) Q1 2025 Earnings Call TranscriptMay 1, 2025 | seekingalpha.comNeoGenomics Pays Off 1.25% Convertible Senior NotesMay 1, 2025 | finance.yahoo.comNeoGenomics (NASDAQ:NEO) Shares Gap Down on Analyst DowngradeMay 1, 2025 | americanbankingnews.comSee More NeoGenomics Headlines Get Earnings Announcements in your inboxWant to stay updated on the latest earnings announcements and upcoming reports for companies like NeoGenomics? Sign up for Earnings360's daily newsletter to receive timely earnings updates on NeoGenomics and other key companies, straight to your email. Email Address About NeoGenomicsNeoGenomics (NASDAQ:NEO) operates a network of cancer-focused testing laboratories in the United States and the United Kingdom. It operates through Clinical Services and Advanced Diagnostics segments. The company offers testing services to hospitals, academic centers, pathologists, oncologists, clinicians, pharmaceutical companies, and clinical laboratories. It also provides cytogenetics testing services to study normal and abnormal chromosomes and their relationship to diseases; fluorescence in-situ hybridization testing services that focus on detecting and locating the presence or absence of specific DNA sequences and genes on chromosomes; flow cytometry testing services to measure the characteristics of cell populations; and immunohistochemistry and digital imaging testing services to localize cellular proteins in tissue section, as well as to allow clients to visualize scanned slides, and perform quantitative analysis for various stains. In addition, the company also provides molecular testing services, which focus on the analysis of DNA and/or RNA, and the structure and function of genes at the molecular level; morphologic analysis, which is the process of analyzing cells under the microscope by a pathologist for the purpose of diagnosis; and testing services in support of its pharmaceutical clients' oncology programs covering discovery and commercialization. NeoGenomics, Inc. was founded in 2001 and is headquartered in Fort Myers, Florida.View NeoGenomics ProfileRead more More Earnings Resources from MarketBeat Earnings Tools Today's Earnings Tomorrow's Earnings Next Week's Earnings Upcoming Earnings Calls Earnings Newsletter Earnings Call Transcripts Earnings Beats & Misses Corporate Guidance Earnings Screener Earnings By Country U.S. Earnings Reports Canadian Earnings Reports U.K. Earnings Reports Latest Articles Archer Stock Eyes Q1 Earnings After UAE UpdatesFord Motor Stock Rises After Earnings, But Momentum May Not Last Broadcom Stock Gets a Lift on Hyperscaler Earnings & CapEx BoostPalantir Stock Drops Despite Stellar Earnings: What's Next?Is Eli Lilly a Buy After Weak Earnings and CVS-Novo Partnership?Is Reddit Stock a Buy, Sell, or Hold After Earnings Release?Warning or Opportunity After Super Micro Computer's Earnings Upcoming Earnings Monster Beverage (5/8/2025)Coinbase Global (5/8/2025)Brookfield (5/8/2025)Anheuser-Busch InBev SA/NV (5/8/2025)ConocoPhillips (5/8/2025)Shopify (5/8/2025)Cheniere Energy (5/8/2025)McKesson (5/8/2025)Enbridge (5/9/2025)Petróleo Brasileiro S.A. - Petrobras (5/12/2025) Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. 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There are 18 speakers on the call. Operator00:00:00Welcome to Speaker 100:00:00the NeoGenomics 4th Quarter and Full Year 2023 Financial Results Conference Call and Webcast. At this time, all participants are in a listen only mode. Please note this call is being recorded and an audio replay will be available on the company's website. Kendra Sweeney, Vice President of Investor Relations, you may begin your conference. Speaker 200:00:22Thank you, John. Good afternoon, everyone, and welcome to the NeoGenomics 4th quarter and full year 2023 financial results call. With me today to discuss the results are Chris Smith, Chief Executive Officer and Jeff Sherman, Chief Financial Officer. Additional members of the management team are available for Q and A, including Vishal Sikri, President of Advanced Diagnostics Warren Stone, President of Clinical Services Melody Harris, President of Enterprise Operations and Ali Olivo, General Counsel and Head of Business Development. Speaker 300:00:54This call Speaker 200:00:54is being simultaneously webcast. We will be referring to a slide presentation that has been posted to the Investors tab on our website at ir. Neogenomics.com. Starting on Slide 2, during this call, we will make forward looking statements regarding our anticipated future performance. We caution you that such statements reflect our best judgment based on factors currently known to us and that actual events or results could differ materially. Speaker 200:01:20Please refer to our most recent Forms 10 ks, 10 Q and 8 ks we filed with the SEC to identify important risks and other factors that may cause our actual results to differ materially from the forward looking statements. The forward looking statements made during this call speak only as of the original date of the call, and we are under no obligation update or revise any of these statements. During this call, in order to provide greater transparency regarding our operating performance, we refer to certain non GAAP financial measures that involve adjustments to GAAP results. The non GAAP financial measures presented should not be considered an alternative to the financial measures required by GAAP, should not be considered measures of liquidity and are unlikely to be comparable to non GAAP financial measures provided by other companies. Any non GAAP financial measures referenced on this call are reconciled to the most directly comparable GAAP financial measure in a table available in the press release we issued this afternoon. Speaker 200:02:18I will now turn the call over to Chris Smith, Chief Executive Officer of NeoGenomics. Speaker 400:02:23Thanks, Kendra, and welcome, everyone. Thanks for joining us this afternoon to go through our Q4 and full year financial results. As always, I really want to begin with our mission and vision statement because it's what motivates our company and teammates on a daily basis. Our mission in Neo is to save lives by improving patient care and we just had our global sales meeting at the end of January And many of our teammates shared how cancer has impacted them or their families and how we're making a difference in their lives. It's always a great reminder of why we do what we do, and I'm so proud of the impact we're having on patients and local communities we serve. Speaker 400:02:58Now let's move to Slide 4 and get into the 4th quarter highlights. As you can see, we had another strong quarter growing revenue 12% over prior year to $156,000,000 Clinical services revenue increased 20% driven by volumes across all our modalities and another increase in revenue per test. As a highlight, NGS grew in excess of 40% and now represents over 25% of our clinical revenue. The strong growth in clinical services helped to mitigate the expected lower revenue in ADX due to a strong comparable in ADX in Q4 of 2022, as well as macro conditions in pharma sector and margin optimization initiatives that we took in 2023. From an adjusted EBITDA perspective, our progress has outpaced our internal plans. Speaker 400:03:44We achieved positive EBITDA in the Q3 of 2023 and significantly improved again this quarter. Adjusted EBITDA was up 900% as compared to Q4 last year to a positive $9,000,000 Adjusted gross profit was $73,000,000 representing a 46.7 percent margin, an improvement of 2 25 basis points compared to Q4 in 2022. Turning to Slide 5 for the full year 2023 results, revenue was up 16% versus prior year to $592,000,000 driven by penetration in the community oncology market, higher volumes, a shift to higher margin modalities and improvements in revenue cycle management. Adjusted gross profit was $264,000,000 representing adjusted gross margins of 44.7 percent and adjusted EBITDA was positive $3,000,000 for the full year, an improvement of $51,500,000 or 107% versus prior year. Now on Slide 6, I'm pleased that the Q4 continued the trend that we've seen throughout 2023 of consistent sequential improvement in revenue, adjusted gross profit and adjusted EBITDA. Speaker 400:05:04Notably, our revenue growth has been strong each quarter of the year. We've built our momentum of reaching positive adjusted EBITDA in Q3 and carried that into Q4. We believe that we've laid solid foundation for growth in 2023 and expect that momentum to continue as we move throughout 2024. Let's move on to Slide 7. As you may recall, at the beginning of the year, we laid out our 4 focus areas for 2023. Speaker 400:05:30They included profitably growing the core business, accelerating advanced diagnostics, driving value creation and enhancing our people and culture. The more time I spend in the business, the more impressed I am with our unique competitive position in the marketplace with a breadth of cancer tests, our operational capabilities and passionate teammates that lead our business every single day. We are a leader in oncology testing with significant share of patient test volume in the U. S. Our deep relationships with community pathologists and oncologists provide us an advantage in the market and our focus on oncology testing has allowed us to develop extensive patient databases and relationships and we view ourselves as a collaborative partner to pathologists, oncologists, hospitals and biopharma companies we serve. Speaker 400:06:18Beyond these market conditions, it's a strong execution by our teammates that enable us to deliver such strong quarterly and full year results to our stakeholders. Our teammates are the foundation of our company and we have strengthened our team throughout the year with key hires at all levels of the organization, including sales, lab operations, corporate functions. These new hires joined a highly talented group of individuals of varying backgrounds and experiences contribute to our distinguished culture that reflects our commitment to diversity, equity and inclusion. This afternoon, I'm going to focus on our 3 financial priorities. We continue to properly grow our core business as we execute on our commercial strategy, protect, expand and acquire, which has contributed to our strong volume growth, increased AUP and improved mix. Speaker 400:07:08Execution of this strategy enabled us to serve more than 6 100,000 patients during the year. Our continued improvement in turnaround time has contributed to or at or above market growth rates across all modalities. In addition, the mix shift towards higher value modalities in tests has supported the delivery of yet another quarterly improvement in revenue per test. Over the last 18 months, we've doubled the size of our sales force increasing coverage and penetration. We also introduced NeoAccess and NeoSeq software solutions to support providers in their clinical decisions and inform patients with upfront benefit checks as well as to identify patients who may be biomarker eligible for new therapies or a clinical trial. Speaker 400:07:50As a result of our increased coverage, clinical support and patient centric mentality, we maintained our customer experience leadership in the market with a 3 point improvement in Net Promoter Score, which is now at 70. Within our advanced diagnostic division, which includes pharma services, informatics and R and D, we continue to focus on acceleration of innovation in R and D. ADX gross margins improved 3 68 basis points over Q4 of 2022. We built a robust product development roadmap to maintain a competitive position in solid tumor therapy selection, MRD and heme, with the goal to gain market share in heme. On the R and D front, we launched 12 new or upgraded assays across heme and solid tumor in 2023. Speaker 400:08:39Within informatics, we announced a collaboration to advance heme research and AI solutions with a data set that covers over a 1000000 patient lives across more than 1,000 oncology clinics. The progress and innovation was displayed throughout the year as we presented new data at several conferences. We have focused on driving value creation from a financial perspective and we are pleased that we have delivered even further margin expansion in Q4 with efficiencies driving enhanced operating leverage. Our enterprise operation team has delivered yet another quarter progress and turnaround time, ending the year with 28% improvement over Q4 of 2022. We have now completed the consolidation of 3 international labs primarily into our Cambridge, UK location. Speaker 400:09:24Earlier this year, we kicked off our LEMS project that will bring all of our prior acquisitions that were utilizing separate LIMS systems onto one platform, which will further enable our digital transformation strategy. We have now completed the 1st phase of user requirements and expect to begin to see the benefits of Lens in the back half of twenty twenty four. Before I hand it over to Jeff, I do want to address the ongoing litigation regarding Radar. It's our policy not to comment on ongoing litigation. However, I will say that Neo is committed to serving cancer patients with MRD testing and we believe that we have several viable pathways to accomplish that. Speaker 400:10:04We've appealed the preliminary injunction of the Federal Circuit and have been granted an expedited hearing, which will occur on March 29. We intend to vigorously pursue the appeal. In addition, we have moved for an administrative stay and a stay pending appeal from the Federal Circuit Court. That briefing was completed February 20. Now let me turn the call over to Jeff to review our Q4 and full year financials in more detail. Speaker 500:10:29Jeff? Thanks, Chris, and good afternoon, everyone. I'll begin with a little more detail on our operating results for the quarter. As Chris said, we continued the year with revenue experiencing double digit growth over prior year. 4th quarter revenue was $156,000,000 a 12% increase over the prior year and a 2.4% increase from Q3 2023. Speaker 500:10:53Revenue growth was driven by growth in clinical test volume, a continuing shift to higher value tests and improvement in revenue per test driven by business mix and revenue cycle improvements. Adjusted EBITDA improved 900% from prior year to positive $9,000,000 Q4 marks the 5th consecutive quarter that adjusted EBITDA increased from prior year. We generated significant operating leverage as revenue favorability flow through to the bottom line with over 60% of revenue growth flowing to adjusted EBITDA. Looking at Slide 9, clinical services revenue of $130,000,000 was an increase of 20% year over year, driven by a 13% improvement in revenue per test and a 6% increase in volume. The growth and optimization of our sales force, along with the effective execution of the commercial strategy, resulted in higher volume growth. Speaker 500:11:50Turning to Slide 10, average revenue per clinical test increased by 13% over prior year to 4 $41 representing an improvement for the 11th consecutive quarter versus prior year as we maintain focus on higher value tests and revenue cycle management initiatives. As we shared with you in the past, NGS is a strategic priority accounts for over 25% of our total clinical revenue for the year. New NGS portfolio additions and the focused effort of our sales team continue to fuel accelerated NGS growth. Turning to Slide 11. As we forecasted on prior quarterly calls, Advanced Diagnostics revenue declined 17% over the prior year in Q4, but was up 5% sequentially to $26,000,000 ADX revenue did grow each of the 1st 3 quarters of 2023 versus 2022. Speaker 500:12:46However, Q4 of 2022 was an unusually strong ADX quarter with revenue growth of over 40% versus prior year. The expected decline in revenue was partially due to macroeconomic conditions and pharma R and D spend as well as our decision to rationalize our global testing sites and low margin contracts. The focus on profitability and margin growth is driving performance in ADX with adjusted gross margins expanding by 3 68 basis points versus the prior year. Similar to our clinical strategy in 2023, we are expanding our ADX sales organization in 2024 to further accelerate profitable growth and expect to see benefits from this initiative as the year progresses. Looking at the income statement on Slide 12, adjusted gross profit increased 17.8% over prior year and adjusted gross margin was 46.7 percent, an improvement of 2 25 basis points over the Q4 of last year. Speaker 500:13:49Adjusted EBITDA was positive $9,000,000 $11,000,000 or 900% improvement versus prior year. These significant improvements were driven by both higher gross profit and disciplined cost management, which highlight the operating leverage in the business. Regarding operational expenses, sales and marketing expense was $18,100,000 as we continue to increase our commercial investment, G and A was $59,800,000 and R and D expense was $7,100,000 Turning to the balance sheet on Slide 13, we ended the 4th quarter with cash and marketable securities of $415,000,000 We continue to make good progress in diligently managing our cash and are focused on accountability and disciplined oversight of operating expenses. Cash flow from operations was a positive $18,000,000 in the quarter, an improvement of $21,500,000 or 5.83 percent from Q4 of 2022. Now let's review our full year 2023 financial results. Speaker 500:14:53Starting on Slide 15, for the year, we increased revenue by 16% over prior year, driven by increases in test volume, revenue per test and NGS revenue in clinical services. Adjusted gross profit increased by 27.5 percent to $264,000,000 as a result of higher revenue and effective cost management. Adjusted EBITDA improved $51,500,000 versus prior year due to improvements in revenue and gross profit. Looking at the balance sheet on Slide 16, we ended the year with cash and marketable securities of 415,000,000 dollars Cash flow from operations improved $64,000,000 or 97% from 2022. This strong performance in reducing our cash burn provides us with multiple avenues to address our upcoming convertible notes due in 2025. Speaker 500:15:45We expect to provide more clarity on our near term maturities on our Q1 2024 financial results call. Now turning to our 2024 outlook. We continue to see strong revenue growth and an increase in NGS product mix and are very encouraged by our new and updated tests, which provide higher operating leverage to the bottom line. We have made the necessary and appropriate investments in our teammates to ensure that we have a world class group of people who are aligned with our mission of serving patients and saving lives. As we continue to build this business brick by brick, I am more confident in our future than ever. Speaker 500:16:26Moving on to Slide 18, for the full year 2024, we expect revenues of $650,000,000 to $660,000,000 representing 10% to 12% growth and adjusted EBITDA to be in a range of $21,000,000 to $24,000,000 representing 600% to 700% growth. In summary, 2023 represented a strong year of execution and financial performance, which positions us well to continue the momentum in 2024. We will continue to invest in growth initiatives, including investments in sales force optimization and expansion in our clinical and ADX businesses and increasing investments in R and D, product and business model innovation to further enhance our menu of tests. In addition, we will be making targeted investments in operating efficiencies, including automation and consolidating our multiple LEMS systems into one consolidated platform over the next 24 months. These investments will drive long term margin growth in the future and are reflected in our annual adjusted EBITDA guidance range. Speaker 500:17:36Based on our cost structure, the revenue growth in 2024 will drive operating leverage and our adjusted EBITDA growth will exceed our revenue growth. We anticipate seasonality of our business to be reflected in each quarter of 2024. Therefore, we expect revenue to be down sequentially in Q1 2024 in a range of $148,000,000 to $151,000,000 representing 8% to 10% growth over prior year and expect our strategic initiatives to drive a higher growth rate as the year progresses. Based on our strong performance in 2023 and our confidence in our strategic initiatives in 2024 and beyond, we are increasing our long range revenue growth target in outlying years from 7% to 9% to 10% plus in our core business excluding MRD. Speaker 400:18:31Thanks, Jeff. I'm very proud of our team's Q4 and full year progress, including strong revenue growth of 16% for 2023 and significant improvement in adjusted EBITDA and cash flow from operations. We saw meaningful progress in the execution on our strategic priorities and therefore we're able to reach the high end of our raised guidance. Our guidance for 2024 and beyond reflects our confidence in our business. We believe we're well on our way to becoming the leading cancer testing information and decision support company. Speaker 400:19:02We will continue to build on the foundation we have laid over the past several quarters to deliver long term sustainable growth. I'm excited for our teammates and our customers and most of all for the patients we serve on a daily basis. Thanks for taking time to connect with us today. I'll throw it back to the operator. Speaker 100:19:20Thank you. At this point, we will open the line for questions. The company asks that each person limit their questions to 1 so that we may hear from everyone within the hour allotted for this call. Okay. And the first question comes from Alex Nowak with Craig Hallum. Speaker 100:20:10Please proceed. Speaker 600:20:11Okay. Great. Good afternoon, everyone. Hey, congrats on the results. I'm sure the potential of FDA coming out and issuing final rules. Speaker 600:20:28Depending on the definition of an LDT, NEO could have a wide variety in its portfolio. Speaker 400:20:33So I'm just curious what you've talked a little bit in the past, but what is Speaker 600:20:37the team internally doing now just in case the FDA does decide, hey, we're going to move forward and issue a final rule? Speaker 400:20:44Yes. Thanks for that. Look, I mean, obviously, we like other companies in our sector are watching that closely. We're on the ACLA board and so I think we've seen it coming. Look, I would say a couple of things. Speaker 400:20:56I would say our progress or our focus on this started probably 18 months ago when we came together as a management team. We started bringing in people who come from regulated backgrounds. So if you think about like the folks on this call, the 3 division presidents, myself, Jeff, all of us come from FDA regulated backgrounds. I think we started to build the quality system that way. We move to one quality system. Speaker 400:21:18We took all the acquisitions and moved them to 1. All of our R and D projects are now under design control. So we've kind of been starting to operate believing this is coming. That being said, there's still a lot to unfold. Once a ruling comes out, I think there's a lot of people in the industry who wonders if it's constitutional. Speaker 400:21:38But from our perspective, we think it's probably not if it's probably when. And it looks like even if all these things could occur, companies are going to have 3 to 3.5 years to get prepared. So we feel very confident in our ability to manage that as it comes on. Look, a lot will depend on what is grandfathered and what is not, but I think we feel really good about our position in the marketplace. And we think for companies like us, it could be end up becoming a competitive advantage. Speaker 400:22:06All right. Thank you so much. Speaker 100:22:09The next question comes from David Westenberg with Piper Sandler. Please proceed. Speaker 500:22:14Hi, David. Hi, David. Thank you. Speaker 700:22:15Hey, great job guys. So I really like the update on the if I heard it right, you updated the long term plan to 10% growth. Can you talk about specifically, because that's a big 150 basis points at least swing there. So what specifically is happening versus that long term growth plan? Where you feel confident that this is not just trend, this is multi year and long term? Speaker 700:22:41And that's assuming I heard that correctly. Speaker 400:22:44Yes, you did. I mean, Jeff put it in there at the end. It's like some of the best news and it was like right at the end. I'll say something and then maybe I'll have Jeff comment more. But look, I think when we gave long term guidance in April of last year, we were pretty new management team. Speaker 400:22:58And I think as we've come together and now had well over a year under our belts, we understand the levers to pull in the business much better. We understand the market significantly better. We understand things around revenue cycle management and accelerated growth and where the gaps are in the products. And so we guided this year for 24% 10% to 12%. But what we're seeing in that core business just because of the market dynamics, the market growth, our leadership position, the things that we can do, we feel very confident in that 10% plus number. Speaker 400:23:28But do you want to? Speaker 500:23:29Yes. I would add to that. We've made multiple comments about adding sales force people to our team and then sales force optimization, we're really focused on how do we help them be more efficient. And so we actually think we can get a lot of operating leverage just through technology and back office support for our sales people, both in our clinical team and in our ADX team. And so I think that's another big component. Speaker 500:23:56We've been growing faster than the market across all modalities. We have a strong focus on NGS and are clearly seeing positive results there. So I think our view is our confidence level has increased based upon our performance in 2023 as well as, as Chris said, the team overall just getting more comfortable with our teams, with our position in the market and where we're investing dollars to raise our long term growth target to that 10% plus. Speaker 400:24:26Yes. And David, I'd say the other one. I mean, if you look at NGS, especially solid tumor, we're incredibly under indexed and you can see that business is growing rapidly. And that market is still relatively penetrated, but growing double digits. So I think there are a lot of factors that we feel really good about where we are from a position perspective. Speaker 700:24:43Great. That's a great segment and a second one because I think you're launching into liquid. So could we expect an accelerated timeline into liquid or like a market traction just given what you're doing right now in hematological malignancies and then you transfer that into solid tumor, which has been going really fast. Speaker 400:25:05Let me let you know obviously a lot going on, but that sits in kind of the R and D group with Vishal and under development. Vishal, do you have anything you want to share just kind of what we're doing with liquid and some of the products that we've disclosed? Speaker 800:25:16Yes, David, thanks for your question. So on the liquid side, we will plan to launch CGP assay for liquid biopsy going into 2024, probably towards the second half of twenty twenty four, but we'll accelerate on the clinical side also that we're looking into. But I do think there is a place for liquid in both the pharma and the clinical side, which we'll see an acceleration in terms of penetration into that market, especially on the pharma side in particular, because we're hearing a lot from pharma companies that they just don't have enough tissue to spread along with all the testing they want to do. So this really gives them the opportunity to choose both liquid or solid from that perspective. Speaker 400:25:55Yes. And you'll probably see that in pharma in late half of the year and then moving into clinical in 2025 early 2020. Speaker 700:26:05Awesome. Great job in the quarter. Speaker 500:26:08Thank you, David. Speaker 100:26:09Up next, we have Puneet Souda with Lyric Partners. Please proceed. Speaker 900:26:14Hey, guys. Chris, Jeff, thanks for taking the questions. How are you doing? I'm good. Thanks, Chris. Speaker 900:26:22I'll wrap my question into 2 questions sort of into 1. Obviously, again, congrats on the LRP increase here. Maybe can you elaborate what is the clinical volume growth that we ought to think about in that sort of long term guide? I mean, at one point, NeoGenomics used to grow that number at 15% growth, but I know the mix has changed today. There's more NGS in here. Speaker 900:26:54So maybe could you elaborate on that? And then how should we think about the AUP and the clinical volume growth this year in 2024? The AUP has continued to ramp throughout the year for clinical in 2023. So just wondering sort of how should we think about that for 2024? Thank you. Speaker 1000:27:12Yes. Maybe I'll take Speaker 400:27:14a little bit of that and throw it to Jeff. But look, the way we think about our business is really portfolio effect. And so if you think about it, we really we have informatics, we have pharma, we have clinical. And obviously, when we look at building out both this year's guidance and next outline year's guidance, we've taken into account all those factors. We have not broken down specifically the units or the AUP. Speaker 400:27:38I will say though on the AUP, 2 things significantly are driving and Jeff will give you more, but one is our mix, right? We're selling a lot more NGS. But the other thing is, we think we have a lot of runway on revenue cycle. And just the amount of when you look at this industry as a whole, I think it's woeful in its ability to get paid for the work that it's doing. And I think where our team is really becoming masterful is identifying those levers, which is probably 15 different levers within that group. Speaker 400:28:05But Jeff, do you have anything else more on what Yes, I think, Speaker 500:28:08I mean, we haven't disclosed specific and we didn't when we gave original guidance, didn't disclose volume or AUP. But I think, as Chris said, given our positioning on both our clinical sales force and revenue I think on the revenue per test or AUP, as Chris said, there's a few things driving that. In the quarter, that NGS mix, I said this last quarter, is driving over 60% of the increase in AUP. So just the NGS volume continue to accelerate is driving meaningful upside in revenue per test. And you can see that stepping up throughout the year in 2023. Speaker 500:28:55And then the other factors, as Chris also said, were revenue cycle specific initiatives. The first is on just getting paid for the work we're doing, a lot of specific initiatives to drive that. We saw good improvement in that in 2023. And then there's also the pricing side where we're having some success in getting price increases as well, where that hasn't historically been a strength of ours. So, as well, where that hasn't historically been a strength of ours. Speaker 500:29:18So again, I think the way I think about the revenue side is we have volume drivers, we have mix drivers, we have pricing drivers and we have RCM drivers and they're going to hit at different intervals and different paces throughout the year. But the overall combination of those is going to get us to our revenue growth over time. Got it. Helpful, guys. Thank you. Speaker 1000:29:41Thank you. Speaker 100:29:42Okay. The next question comes from Matt Sykes with Goldman Sachs. Please proceed. Speaker 1000:29:47Hey, Matt. Speaker 1100:29:47Hey, good afternoon. Hey, guys. How are you doing? Congrats on the quarter. Maybe just following up on Puneet's question, but focusing on the mix side of it. Speaker 1100:29:56Obviously, the NGS mix you guys have talked about and that's driving a lot of that. But I'm just wondering in terms of like as you think about the runway for mix shift, there's clearly probably customer groups where it was easier to kind of switch them into NGS or market the NGS to them. Does mix shift get harder you think over the course of this year and into 2025? Or do you just see a lot of runway and lack of awareness where you're able to continue to drive that mix shift over time? And then just my second part, just quick one for Jeff. Speaker 1100:30:24Just any views on the gross margin outlook for 2024 within that guide? Speaker 400:30:29Yes. Thanks, Matt. Look, I think when you look at this business, one of the things that we really like as we've gotten to know the business well is that we're very under indexed both on NGS as the total percentage of revenue for the company as well as in solid tumor. And do you think there's going to be some earning calls that come up in 90% of the revenue is NGS. And so I think we believe very strongly I think in that ability on that mix shift. Speaker 400:30:52I'd say the second big one is, I think you could argue this year should be better because of our increased focus going to oncology, community oncologists versus just the hospitals and the pathologists and expanding that sales force there and to be able to go out and spend time. Look, one of our lever points is that we're the market leader in heat and really using that to be a door opener for us for Solid. But maybe I probably shouldn't even say as much as I did Warren's here, but maybe Warren give more maybe more color. Operator00:31:23Yes. Chris, Speaker 1000:31:23I think everything you just said, I agree with 100%. I mean, we've communicated that right now the ratio is roughly 25% of the business. I think as that ratio increases, certainly it gets marginally harder. But I wouldn't discount the fact that we have launched new products last year. It was probably mid year by the time we were starting to see some traction take place. Speaker 1000:31:43So looking to benefit from the annualization of those new products that were launched in last year, particularly those are NGS related. So that's one that certainly will provide opportunity for us. And then as Chris said, the continued penetration into the community oncology segment, which is where we've invested a lot of incremental sales resources into is another reason why we believe we can drive growth in NGS, which will support that mix shift. Operator00:32:09Jeff, do you want to take that? Speaker 500:32:10Yes. Then on the margin side, Matt, I would look at adjusted gross margins increasing in a range of 150 basis points to 175 basis points over the next year over 2024. Great. Operator00:32:25Thanks guys. Speaker 100:32:26Thank you. Next we have Andrew Breckman with William Blair. Andrew, please proceed. Operator00:32:33Hi, guys. Good afternoon. Hey, Chris. Thanks for taking the questions. Maybe on the inorganic front, I guess as you guys are making progress here on increasing profitability, can you just sort of talk about balancing that dynamic with your sort of appetite for adding to the bag here over time? Operator00:32:48Any considerations that we should sort of be thinking about? Thanks. Speaker 400:32:51Yes. Andrew, I got to tell you, I missed the very first thing you said. What? No. Inorganic growth. Speaker 400:32:57Okay. Sorry, I missed that. Yes, look, I think it's a unique scenario when a company looks at accelerating growth and how much do you put on the bottom line versus how much do you invest. We believe that this business has a very unique opportunity to grow low double digits on revenue and mid teens plus on profitability. I think for us, we look at where we can invest the dollars that we think are going to give a long term ROI. Speaker 400:33:25So we spend a lot of time as a leadership team talking about what these initiatives are and when are we going to strategically invest in them. So for example, this year, one of the big ones is LEMS. Last year, a big one was expanding the clinical sales force. So we believe that you can have that balance. Like Jeff always says, it's not either or, it's and. Speaker 400:33:43And I think our view is that we want to grow revenue fast, gross margins faster and operating profit fastest. And I think we run our business to do that. So I think we feel really good about that balance. But Jeff, do you want to get from a financial perspective? Yes. Speaker 500:33:57I think the other thing that gives us confidence is just our capital structure as well and our ability to really significantly change our cash burn and actually position ourselves for actually starting to produce cash in 20 25. So I think having the clear path to being adjusted EBITDA positive for all of 2023 and certainly we expect effort for 2024. And then really it's an investment, I think, rigor and discipline that we have used over the last 12 months, where are we going to be investing dollars and how are we doing that in a strategic fashion over time to drive the business. And I think as Chris said, clearly with having ROI projects that are going to pay for themselves over time. And I just think we've had a lot more rigor and discipline in the process, which gives us confidence in the investments we've made. Operator00:34:57Okay. Thanks guys. Speaker 100:35:00Up next, we have Mark Massaro with BTIG. Please proceed. Speaker 800:35:04Hey, Mark. Speaker 1200:35:06Hey Chris, how's it going? Speaker 400:35:08Good. Speaker 1200:35:10Yes, congrats on the quarter. Lots of great progress on the clinical side. I guess my question is more on pharma services. I know your predecessors talked a lot about pharma services and informatics And there is a large precision oncology company out there that's monetizing big data with some pretty sizable revenue. So I'm just curious like you guys are doing a great job just growing revenue and profitability. Speaker 1200:35:41Maybe just give us an update on how you see the pharma services business shaping out? How you can monetize some of the big data? And maybe just give us a sense for how you're thinking about the growth of that business going forward? Speaker 400:35:55Yes, thanks. Look, I think when we came in, I mean, I think the first thing is we made a very conscious decision that that business had a lot of pieces to it that were not profitable. And so our focus was and we've talked about this in the whole company, but especially in pharma, let's get the house in order. And let's get this gross margin moving and you can see that we've made great progress in there. I think when we think about the pharma business, so we do believe it's kind of the tip of the spear from a technology perspective because the pharma companies go well in front of clinical on new innovations and new technology. Speaker 400:36:29And we saw that, for example, in MRD. So we believe it's a place to be. But before we could start accelerating growth, we had to get the baseline right. And that's what 2023 was all about. And now you heard that, Jeff, one of our last year, we spent a lot of money and time expanding the clinical sales force. Speaker 400:36:44We're expanding now the pharma and the informatics sales force because we feel like there's great growth opportunities there, but we felt like we had to direct kind of right to shift first. On informatics, we have significant points of data because of our the patients that we test. And I think as Vishal and I'll let Vishal step in and maybe talk more about the informatics. But I think as Vishal and Melody come together and kind of look at the things that we can do, there is runway, but there's a lot of work to do. And I think that the company you're probably referring to, it was not our top priority, but it's becoming more of a priority. Speaker 400:37:17But I think for us, again, it's about the portfolio. We got to be able to perform in clinical and all of ADX. Do you want to talk more about specialty informatics and the data? Speaker 800:37:27Yes. I think as we look at the data that we have within the company, one of the nice things about what NEO has is data across all of our modalities whereas others maybe will have it primarily in NGS. But as we grow our NGS product portfolio, our data will also grow at the same time. So what we can get to in a couple of years is going to be much different than where we are today in terms of our data offerings as a whole. And on top of that, the LEMS investment that we're doing, which will allow us to structure the data in the right way, will also make us successful for the informatics side. Speaker 800:37:58So altogether, the next couple of years, we still have a long way to go there. I mean, I think we have to build in the right steps. But how we're building it is more important right now for the next year and getting 2 years out as to what we can do with that data from where we are today. Speaker 1200:38:15Sounds good. Congrats on the progress. Speaker 500:38:17Thanks Mark. Speaker 100:38:19The next question comes from Mike Matson with Needham and Company. Please proceed. Speaker 600:38:24Hi, Mike. Hi, guys. Just wanted to ask one on the LIMS project. So you mentioned you could start to see some of Operator00:38:33the benefits of that in Speaker 600:38:34the second half. So So just curious what those benefits could be? I mean, is it margins? Is it per turnaround time? Is it market share or all of the above? Speaker 400:38:47Yes. Look, I think there's a lot. It's probably all of the above. And Melody is on the call as well. Melody, do you want to take that initially and then Jeff maybe could talk about financial stuff with Melody? Speaker 300:38:58Sure. I think first and foremost, Mike, it's really around operational efficiency and productivity in the lab. So I think we're going to we're expecting to see a lot of pickup with regard to leverage there because we currently are on multiple different systems. And obviously, that causes a lot of cutting and pacing and things like that, that we're hoping to eliminate. But as far as then, Vishal mentioned the ability to use our data better, it's really an overall enterprise digital architecture that we're working and wins is the start of that. Speaker 300:39:36But we're also leveraging various platforms for better connectivity to our patients, better connectivity to EMR, better connectivity into our billing systems and our back end ERP. And the LIMS system is really the big driver for all of that for us. Jeff, comments on the cost structure? Speaker 500:39:58Yes. And I would add one other thing as well. I mean, it will give us just better visibility from client service perspective on where our tests are in the process and allow for really self-service on where tests are in the process. So I think it helps our client communication and giving them up to date on where we are with the testing process. And then we are making capital investments that will have some operating expenses with that over the next 2 years. Speaker 500:40:26So we have factored in those operating expenses into our guidance. And again, I think this is one of those investments that is going to pay long term dividends. We'll start seeing it on the gross margin side as Melanie noted from an efficiency standpoint. And I think over time, it could have top side benefits as well as we improve our client service. Speaker 400:40:47Yes. And maybe Warren, you can talk to this, but look, we're spending probably as much on the customer experience component Speaker 800:40:54as we Speaker 400:40:54are on the lens as far as digitization. And it's interesting, I think in this business for us to ultimately get to where we want to go, we got to win on customer experience and we got to win on the ability to serve the patient. And I think you want to just give what we're doing on the digitization and the platform. Yes. That's going to tie to limb. Speaker 1000:41:13Yes. Building on what Meny said in terms of Lens being the sort of foundational element for us to start a digital transformation, this is providing the building blocks for us. And additionally, we're investing in what we're calling a digital front door to our customers, which will be the platform for self-service. It will be the platform to allow customers to track the status of testing in real time, something that is certainly missing today. And ultimately, it will allow us to increase stickiness to those customers, which is an important element from our protect, expand, acquire commercial strategy. Speaker 1000:41:49So something else that we look to expect to see value in the latter part of 2024. Thanks. Speaker 600:41:56Great. Thanks. Speaker 100:42:02Okay. Your next question comes from Mason Carrico with Stephens Inc. Please proceed. Speaker 500:42:07Hey, Mason. Hey, guys. Speaker 1300:42:10Thanks for the question here. So for the ADX business, you had called out, you framed it up in previous quarters, these the headwinds that you'd be facing, rationalizing some testing sites, low margin business as well as you're facing some macro conditions. So I guess the question is, could you kind of break out, I guess, how much of an impact each of those 2 buckets have? And as we look ahead into this year, when do you think we start to lap kind of rationalizing that low margin business going forward? And really how are you thinking about accelerating growth in this business this year? Speaker 400:42:51Yes. Why don't I take it upfront and then Vishal can pick it up. I mean, we made that decision, but those contracts took some time. So I think you'll start to see that piece start to kick in probably in the second half of the year. We haven't broken out where the impact is. Speaker 400:43:07But I think even more importantly, Vishan, maybe talk about strategically all the things that your team is doing in other modalities just NGS and why that's still relatively new and why you give confidence in the acceleration of the growth? Speaker 800:43:19Yes. If you look at what pharma is coming up to us for, right, we are still investing heavily in modalities, what I call our traditional modalities like IAC. That's not going anywhere from an oncology pharma perspective. That's our bread and butter. But as we launch new products in the NGS side in particular, and we're seeing that trend. Speaker 800:43:41And as Chris mentioned, usually what we see in pharma is a movement and moving towards technologies 3 to 5 years ahead of clinical. We're already seeing that trend moving from FISH as an example to NGS. We didn't have the right products until we launched them last year. So we're starting to see that movement into more and more usage cases in NGS, which also have higher AUPs for that matter. So we're also investing in our BD team. Speaker 800:44:07We invested a lot in the clinical side from a sales perspective. We're investing now on the ADX side and rebuilding that BD team and making sure that we have the tools and expertise that will allow us to grow in 2024. Speaker 400:44:19Maybe talk about liquid biopsy because that's going to be a big product Speaker 900:44:22for you guys. Speaker 800:44:23Yes. Liquid biopsy is something that we get approached by from pharma all the time is we do a lot of tissue testing right now, which is what we've built our business on. But on the liquid side, especially for solid tumor and as Chris mentioned earlier, we're very much under penetrated on the solid tumor side because we didn't have the right product mix. And now we're launching our liquid bio XCGP, which will allow us to make that offering to pharma where they don't have tissue to give to us for samples that have been sitting around 3, 5 years to 10 years old from clinical trials that have been completed. So we're able to go back and actually try and get some of that business with our new offering that we're planning to launch this year. Speaker 500:45:03That's helpful. Thanks guys. Operator00:45:05You too. Speaker 100:45:07Up next, we have Andrew Cooper with Raymond James. Please proceed. Speaker 400:45:11Hey, Andrew. Speaker 1400:45:12Hey, guys. Thanks for the time. Maybe just first focusing on price for a little bit here or AUP, I should say. Can you just give a sense for how much more runway is there in that 40 percent of the increase that's come from RCM and price? Or maybe ask another way, what can we expect that to contribute on a yearly basis once mix is stabilized or in the scenario where kind of on an apples to apples basis we think about mix being stabilized? Speaker 1000:45:41Yes. Speaker 500:45:44Without kind of getting into granular specifics, we said earlier NGS was driving about 60%. We are still seeing mix improvement in other aspects of the business, which is driving a component of AUP or revenue per test as well. I think in terms of the initiatives, we think pricing is a multi year opportunity for us. And we also think the revenue cycle initiatives that are just increasing the amounts where we're getting paid for what we expect to be paid is a multiyear opportunity. So I think we have multiple year opportunity to continue to close the gap between what we're expected to be paid and what we are being paid. Speaker 500:46:29And again, as I've said in prior calls, it is multifaceted. I mean, there are some other clearly identifiable areas of prior authorizations or medical necessity or medical records that we're dealing with. And then there's the payer policy aspects, which are a little bit harder, particularly with the larger panel tests. And so as some of the biomarker legislation gets approved gets approved in states over time, that will also help close the gap for specific tests where we may not be getting reimbursed today or where we're not being reimbursed fully. So again, I think there's a lot of different areas that we've identified that we have teams working on to close that gap and see a multiyear runway. Speaker 1400:47:14Okay, great. And then maybe just one more. On the LRP update, obviously, great to see. Maybe just any context for what that does or doesn't do to the EBITDA margin expectations that you laid out back in April and whether that number can be a little bit higher for 26% or maybe how we think about even beyond that timeframe where adjusted EBITDA margins might go in the event of kind of that little bit faster revenue growth? Speaker 500:47:41Yes. So what we said almost a year ago was we expected EBITDA margins to be in the mid to high teens by 2027. Obviously, going towards the higher end of going to above the high end of that range, I think will help accelerate that. I don't know that it changes meaningfully when we achieve that mid to high teens, but it could pull it forward, I think, a period of time. And also just our ability to generate operating leverage off that revenue growth, I think will help the adjusted adjusted EBITDA growth over time as well. Speaker 500:48:21We initially said we expected to be adjusted EBITDA positive in 2024. Obviously, we achieved that in 2023. So again, almost probably pulling forward somewhat a year on that front. So I think as we look at our ability to generate operating leverage on the revenue growth, it clearly will benefit our long range plan from an adjusted EBITDA and adjusted gross margin basis. Speaker 400:48:45Yes, Andrew, I think as we like I talked about earlier, as we've seen the levers and the ability pull multiple ones to get leverage and pull through on this business. You saw this year the significant amount of our growth drop into the bottom line. And so I think that we that's enhanced kind of our confidence in some of these things. Now we still have things like value capture program where we want to go get anywhere from $10,000,000 to $15,000,000 a year. We want to improve gross margins and get gross margin leverage by 100 basis points every half. Speaker 400:49:15I mean, all those are fundamental. But I think now, like when you think about Melody, on her side on the operations, she now has the detailed plans in place and we can see that. So I think it just has given us a greater sense of confidence in our ability to deliver it. Speaker 1400:49:29Great. I'll stop there. Thanks again, guys. Speaker 500:49:32Thanks. The Speaker 100:49:34next question comes from Derik De Bruin with Bank of America. Derik, please proceed. Speaker 500:49:39Hey Derik. Speaker 1500:49:41Hey, good afternoon. You have John Kim for Derek here. I'm going to try to ask this one more time. Great to hear the 2024 guide and update on the long term guide here. Any other details that you could share on what the split is going to be between the clinical services and advanced diagnostics? Speaker 1500:50:06I think you previously talked about how the clinical services would be a bigger portion of the sales, but yes, would be helpful to know any additional thoughts that you might have? Speaker 500:50:17Yes. We have as Chris said earlier, we really view it as an overall portfolio and we guide on a portfolio basis. So we haven't broken out that individually. We do expect both of them to grow in the year. We just haven't broken it out and don't plan on breaking out in our guidance. Speaker 1500:50:37Got you. And I did want to ask about the patent infringement ruling against radar that was in December. Any expectations as to I know it's not included in the guidance, so not expecting any financial impact there on the top line or the bottom line. But any expectations in terms of when you think this might get resolved or like if it comes to getting rid of it, what impact that could have on the bottom line? Speaker 400:51:13Yes, I'm going to let Ali address the legal questions, but two quick points. So our guide does not include any radar in it, number 1. But number 2, we do believe MRD is important. So I'll just put that and then I'll throw it to Ali to let her kind of walk through how the legal side is going. Operator00:51:29Sure. Speaker 1600:51:30We don't have any visibility to the timing. What we know is that we've requested an expedited hearing and we've been granted that expedition and the hearing was, as Chris said, on March is scheduled for March 29. And so various factors kind of contribute to the Federal Circuit Court of Appeals timing on a decision, including whether or not the decision is precedential, whether there's a dissenting opinion on the panel of 3 judges. We have also made a motion for a stay pending the appeal. And that motion was fully briefed, like Chris said, as of today. Speaker 1600:52:10And so timing on that is within a couple of weeks. That's sort of what we know in terms of timing on the appeal. As far as the infringement matters in district court, those are ongoing and are in Speaker 400:52:26the discovery stage. The North Carolina case has been Speaker 1600:52:26set for trial in 25. Speaker 200:52:35Appreciate all the Speaker 100:52:47Up next, we have Tejas Savat with Morgan Stanley. Please proceed. Speaker 1700:52:52Hey, guys. Good evening. Sajid, I just wanted to push on that similar line of questioning there. I was curious, Chris, in terms of the comments you made in your prepared remarks about your options available here, right? Can you give us a sense for how quickly you could pivot to perhaps a new version of Radar as a workaround for the litigation? Speaker 1700:53:17And that's something we've seen other peers in the industry resort to in relatively short order. And I was curious if that Speaker 400:53:26was an option that you were actively Speaker 1700:53:26exploring at the moment as well. Speaker 400:53:32Tejas, thanks. Look, I would say that we're actively exploring all options around MRD with the first situation that we believe, vinaciously about our position from a legal. So I mean, obviously, that's where we're going. That being said, we have been in development for additional MRD products beginning probably 12 months before this even started. So I would say that that's been ongoing. Speaker 400:53:56And I would say with us, we believe like a lot of the products that we're trying to bring to market, we think there's an incredible need from a patient perspective, especially for products that continue to improve sensitivity. And I would say that Vishal and the team in R and D operate with an incredible sense of urgency. But it's not just from a technology perspective, but it's from an IT perspective that they're looking at us from a commercialization perspective. But we haven't given any timelines just that we're operating with a sense of urgency on it. Speaker 1700:54:28Got it. Fair enough. And then just one quick follow-up for me on the biomarker bill. Can you lay out, Chris, what proportion of your tests you think could benefit from incremental commercial payer coverage here, given even the states that have currently passed the legislation? Speaker 1000:54:47I don't think so very clearly, where we believe the value will come is on any NGS test, which is a panel of 50 or larger gene. That's where today reimbursement from a 3rd party payer perspective is quite limited. So that's where we see the benefit. In terms of I think what portion of our business that is etcetera, that's something we actually haven't commented on. Speaker 400:55:10And one of the things we'll talk more about some of the strategic priorities in 24 when we get together after Q1. But one of them is to launch our Neo comprehensive 2.0, which is a significant larger panel. And so obviously that will be an important tool for us. Speaker 1700:55:27Got it. That's helpful. Appreciate the time guys. Speaker 500:55:30All right. Thanks. Thanks. Take care. Speaker 100:55:33The next question comes from Dan Brennan with TD Cowen. Please proceed. Speaker 400:55:37Hey, Dan. Operator00:55:38Hey, thanks for hey, good morning, Chris or good afternoon, excuse me. Maybe just a question back to the liquid offering. Any color on what type of reimbursement we can expect? And how should we think about framing the opportunity from like a revenue potential perspective? Speaker 400:55:55You want to take that? Talk a little bit about what's going on in the market? Speaker 800:55:59Yes. So the good news here is that, I mean, there is reimbursement that's established similar to what you see with the tissue test. And we expect something from a reimbursement perspective, at least for Medicare, would be in the similar type dollar amount as what we see on the tissue side of things with potential for higher depending on what kind of status we get on this. But the reality is that we're also seeing NCCN guidelines get tissue or liquid being done at the same time or independent of each other. So I think you're seeing the guidelines are changing and that also helps with the whole reimbursement story and the clinical adoption of course, especially in the community based setting. Speaker 800:56:55So I think having a liquid offering that is widespread is going to be critical for us for commercial growth. Operator00:57:03Great. And then maybe just sticking with NGS, clinical market volumes probably growing north of 30. Just wondering, for your volume growth, how much if we're thinking about like the market growth versus converting your customers from, say, legacy test to NGS, Could you just give us a sense of like maybe I know you're not going to distill the exact numbers for each, but I'm just wondering how far along your customers are and is that a big driver for you that you're kind of bringing forward some of these more community hospitals and doctors towards MGS? Thank you. Speaker 400:57:37Yes. I'll let Warren take it. But remember, we have 3 distinct strategies that we focus on and really from a field compensation perspective, they're incentivized on all of them. Do you want to talk a little bit about what's going on? Yes. Speaker 400:57:48I think there's a Speaker 1000:57:48couple of dynamics that are taking place. Certainly, we've got customers that may not be using NGS today using a different modality that we're moving into NGS. That's the first kind of motion. 2nd is we have a number of smaller gene single gene and smaller panels that are available and these we're moving customers to larger panels. And then obviously, we have the dynamic of customers which haven't been near customers in the past that are now we're now addressing and this is particularly relevant in the community oncology setting. Speaker 1000:58:21So those are kind of the 3 kind of areas where we see sort of growth from an NGS perspective. And it really plays into with our commercial strategy, which again it's around protecting existing customers, but secondly expanding share of wallet where we drive various sort of GAAP analysis strategy to identify which customers to target with different NGS offerings, which could be one of those 3, not using NGS moving to NGS or using a single or small panel into a larger panel. And then thirdly, it's the acquire element of our commercial strategy, which is gaining customers, which haven't been supportive of NIO in the past. Speaker 400:59:01And that third one is obviously the toughest, getting new customers, but it's by far the biggest opportunity where we just hadn't been spending time till starting about 12 months ago, which is those community oncologists. Speaker 500:59:12Great. Thank you. Speaker 400:59:14Thank you. Speaker 100:59:16We have reached the end of the question and answer session. And I will now turn the call over to Chris Smith for closing remarks. Speaker 400:59:23Okay. Thank you. Look, I just appreciate everybody taking the time to get together and get some more color on what's going on inside the business. We kind of talked about the state of the business. And I think we feel incredibly good about where the business is and where the business is heading. Speaker 400:59:39I think we're ahead of where we thought the early plans are being. And I think as we continue to go forward each quarter, we'll try to give you more insight into the business and how we continue to build this long term sustainable growth. Again, thanks for your time today and take care.Read morePowered by