HCW Biologics (NASDAQ:HCWB), Inc. is a clinical-stage biopharmaceutical company focused on the development of antigen-specific immunotherapies for autoimmune and inflammatory diseases. The company’s proprietary intradermal delivery platform is designed to induce immune tolerance by presenting disease-relevant antigens directly to skin-resident dendritic cells. This targeted approach aims to modulate pathogenic immune responses while preserving overall immune function, with an initial focus on systemic lupus erythematosus (SLE).
At the core of HCW Biologics’ pipeline is its lead candidate, HCB101, which is currently in Phase II clinical trials for patients with moderate to severe SLE. Additional programs include preclinical immunotherapies for multiple sclerosis and rheumatoid arthritis, each leveraging the same antigen-specific tolerance technology. Preclinical data have demonstrated promising safety and biological activity, supporting the company’s strategy to expand its portfolio into other autoimmune indications.
Founded in 2016 by immunologist Dr. Hong-Chi Wang, HCW Biologics is headquartered in San Diego, California, with research collaborations spanning North America, Europe and Asia. The company has established partnerships with leading academic institutions to advance its clinical programs and refine its delivery technology. This global footprint supports HCW Biologics’ ambition to address significant unmet needs in autoimmunity and inflammatory disease worldwide.
HCW Biologics is led by President and Chief Executive Officer Dr. Ping Lin, who brings over two decades of biopharmaceutical leadership experience, and Chief Scientific Officer Dr. Maria Chen, a veteran immunologist. Under this management team, the company continues its clinical development efforts, seeks strategic collaborations, and prepares for potential commercialization of its novel immunotherapies. HCW Biologics remains committed to delivering safe, effective treatments that restore immune balance in patients living with chronic autoimmune diseases.
