NASDAQ:ALMS Alumis (ALMS) Stock Price, News & Analysis $4.19 -0.21 (-4.86%) As of 10:50 AM Eastern This is a fair market value price provided by Polygon.io. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock About Alumis Stock (NASDAQ:ALMS) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get Alumis alerts:Sign Up Key Stats Today's Range$4.15▼$4.5550-Day Range$3.57▼$10.0752-Week Range$3.18▼$13.53Volume53,176 shsAverage Volume319,321 shsMarket Capitalization$197.67 millionP/E RatioN/ADividend YieldN/APrice Target$25.86Consensus RatingBuy Company OverviewOur mission is to significantly improve the lives of patients by replacing broad immunosuppression with targeted therapies. Our name, Alumis, captures our mission to enlighten immunology, and is inspired by the words "allumer"-French for illuminate-and "immunis"-Latin for the immune system. We are a clinical stage biopharmaceutical company with an initial focus on developing our two Tyrosine Kinase 2 (TYK2) inhibitors: ESK-001, a second-generation inhibitor that we are developing to maximize target inhibition and optimize tolerability, and A-005, a central nervous system (CNS) penetrant molecule. ESK-001 has demonstrated significant therapeutic effect in our Phase 2 program in patients with PsO, which we define as moderate-to-severe plaque psoriasis (PsO), and is currently being evaluated in an additional Phase 2 clinical trial in patients with systemic lupus erythematosus (SLE), for which we expect to report results in 2026. With the favorable results in our Phase 2 clinical trial in PsO, we intend to initiate multiple Phase 3 clinical trials of ESK-001 in the second half of 2024 in this indication. TYK2 genetic mutations are associated with a strong protective effect in multiple sclerosis, motivating us to develop our second product candidate, A-005, as a CNS-penetrant, allosteric TYK2 inhibitor for neuroinflammatory and neurodegenerative diseases. In April 2024, we initiated our Phase 1 program of A-005 in healthy volunteers and expect to report initial results by the end of 2024. We utilize our proprietary precision data analytics platform, biological insights and team of experienced research and development experts to deepen our understanding of disease pathologies, accelerate research and development and increase the probability of clinical success. Our collective insights informed our selection of TYK2 as the target for our two lead programs. Beyond TYK2, our proprietary precision data analytics platform and drug discovery expertise have led to the identification of additional preclinical programs that exemplify our precision approach. We recognize that patients living with immune-mediated diseases need alternatives to currently available therapies. Despite recent advances and innovations in the treatment of immune-mediated diseases, many patients continue to suffer, cycling through currently approved therapies while looking for a solution that alleviates the debilitating impact of their disease without life-limiting side effects. Addressing the needs of these patients is why we exist. We are pioneering a precision approach that leverages insights derived from powerful data analytics to select the right target, right molecule, right indication, right patient, right endpoint and right combination to dramatically improve patient outcomes. We believe that combining our insights with an integrated approach to drug development will produce the next generation of treatments to address immune dysfunction. We were founded in January 2021 as a Delaware corporation under the name FL2021-001, Inc. We changed our name to Esker Therapeutics, Inc. in March 2021, and subsequently to Alumis Inc. in January 2022. Our principal executive offices are located at 280 East Grand Avenue, South San Francisco, California.Read More… Alumis Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks47th Percentile Overall ScoreALMS MarketRank™: Alumis scored higher than 47% of companies evaluated by MarketBeat, and ranked 547th out of 916 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.6 / 5Analyst RatingBuy Consensus RatingAlumis has received a consensus rating of Buy. The company's average rating score is 3.22, and is based on 7 buy ratings, no hold ratings, and no sell ratings.Amount of Analyst CoverageAlumis has only been the subject of 2 research reports in the past 90 days.Read more about Alumis' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Alumis are expected to grow in the coming year, from ($8.51) to ($4.19) per share.Read more about Alumis' valuation and earnings. Short InterestN/AShort Interest LevelN/A Short InterestThere is no current short interest data available for ALMS. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldAlumis does not currently pay a dividend.Dividend GrowthAlumis does not have a long track record of dividend growth. Sustainability and ESGN/AEnvironmental ScoreN/A Short InterestThere is no current short interest data available for ALMS. News and Social Media2.7 / 5News Sentiment0.82 News SentimentAlumis has a news sentiment score of 0.82. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.70 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 8 news articles for Alumis this week, compared to 4 articles on an average week.Search InterestOnly 7 people have searched for ALMS on MarketBeat in the last 30 days. This is a decrease of -36% compared to the previous 30 days.MarketBeat FollowsOnly 1 people have added Alumis to their MarketBeat watchlist in the last 30 days. This is a decrease of 0% compared to the previous 30 days. Company Ownership1.7 / 5Insider TradingAcquiring Shares Insider Buying vs. Insider SellingIn the past three months, Alumis insiders have bought more of their company's stock than they have sold. Specifically, they have bought $213,031.00 in company stock and sold $0.00 in company stock.Read more about Alumis' insider trading history. Receive ALMS Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Alumis and its competitors with MarketBeat's FREE daily newsletter. Email Address ALMS Stock News Headlines3 Biopharmaceutical Stocks Bucking the Sell-OffThree biopharma companies may appeal to investors looking for firms that have not been rocked by tariff-inspired turbulence.April 10, 2025 | marketbeat.comACELYRIN urges stockholders to approve Alumis mergerMay 3 at 2:35 PM | investing.comWatch This Robotics Demo Before July 23rdJeff Brown, the tech legend who picked shares of Nvidia in 2016 before they jumped by more than 22,000%... Just did a demo of what Nvidia’s CEO said will be "the first multitrillion-dollar robotics industry."May 6, 2025 | Brownstone Research (Ad)Alumis (NASDAQ:ALMS) Given Buy Rating at HC WainwrightMay 3 at 2:45 AM | americanbankingnews.comACELYRIN, Inc. Urges Stockholders to Vote in Favor of Proposed Merger with Alumis Inc. Ahead of May 13, 2025 MeetingMay 1, 2025 | quiverquant.comAcelyrin gains as Trium Capital rebuffs M&A deal with AlumisApril 29, 2025 | msn.comHC Wainwright Has Positive Estimate for Alumis Q1 EarningsApril 26, 2025 | americanbankingnews.comAlumis price target lowered to $14 from $15 at H.C. WainwrightApril 22, 2025 | markets.businessinsider.comSee More Headlines ALMS Stock Analysis - Frequently Asked Questions How have ALMS shares performed this year? Alumis' stock was trading at $7.86 on January 1st, 2025. Since then, ALMS stock has decreased by 44.0% and is now trading at $4.40. View the best growth stocks for 2025 here. When did Alumis IPO? Alumis (ALMS) raised $210 million in an IPO on Friday, June 28th 2024. The company issued 13,125,000 shares at a price of $16.00 per share. Who are Alumis' major shareholders? Alumis' top institutional shareholders include Bank of New York Mellon Corp (0.09%) and Rhumbline Advisers (0.04%). View institutional ownership trends. How do I buy shares of Alumis? Shares of ALMS stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Alumis own? Based on aggregate information from My MarketBeat watchlists, some other companies that Alumis investors own include Comstock (LODE), Ashford Hospitality Trust (AHT), Artificial Intelligence Technology Solutions (AITX), Allakos (ALLK), BioXcel Therapeutics (BTAI), Clearside Biomedical (CLSD) and Delcath Systems (DCTH). Company Calendar Today5/05/2025Next Earnings (Estimated)6/18/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry Pharmaceutical preparations Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:ALMS Previous SymbolNASDAQ:ALMS CIK1847367 WebN/A Phone(650) 231-6625FaxN/AEmployeesN/AYear FoundedN/APrice Target and Rating Average Stock Price Target$25.86 High Stock Price Target$36.00 Low Stock Price Target$13.00 Potential Upside/Downside+487.7%Consensus RatingBuy Rating Score (0-4)3.22 Research Coverage9 Analysts Profitability EPS (Most Recent Fiscal Year)N/A Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet IncomeN/A Net MarginsN/A Pretax MarginN/A Return on EquityN/A Return on AssetsN/A Debt Debt-to-Equity RatioN/A Current Ratio11.26 Quick Ratio11.26 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book ValueN/A Price / BookN/AMiscellaneous Outstanding Shares47,222,000Free FloatN/AMarket Cap$207.78 million OptionableN/A BetaN/A A Beginner's Guide to Investing in CannabisUnlock your free copy of MarketBeat's comprehensive guide to pot stock investing and discover which cannabis companies are poised for growth. Plus, you'll get exclusive access to our daily newsletter with expert stock recommendations from Wall Street's top analysts.Get This Free Report This page (NASDAQ:ALMS) was last updated on 5/6/2025 by MarketBeat.com Staff From Our PartnersElon’s Terrifying Warning Forces Trump To Take ActionElon Musk has avoided two major financial crises before. He pulled Tesla and SpaceX back from the brink of col...American Hartford Gold | SponsoredTrump wipes out trillions overnight…Is there anybody more powerful than Donald Trump right now? In a single tariff announcement, he wiped out n...Porter & Company | SponsoredGold Hits New Highs as Global Markets SpiralWhen Trump took office in 2017, gold was just $1,100 an ounce. 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