Day One Biopharmaceuticals (DAWN) Stock Price, News & Analysis

Company Overview

Day One Biopharmaceuticals (NASDAQ:DAWN) is a clinical-stage biotechnology company dedicated to developing precision therapies for patients with solid tumors. The company’s research focuses on designing small molecules that target key drivers of cancer growth and survival, including hormone receptors and cell cycle regulators. Its lead candidate, camizestrant, is an oral selective estrogen receptor degrader (SERD) currently in late-stage development for the treatment of estrogen receptor-positive, HER2-negative advanced breast cancer.

Beyond its lead program, Day One leverages a proprietary discovery platform to advance additional candidates across multiple oncology targets. Early-stage assets include novel molecules aimed at disrupting oncogenic signaling and DNA damage repair pathways. The company’s pipeline strategy emphasizes differentiated mechanisms of action designed to address areas of high unmet medical need and to overcome resistance to existing therapies.

Founded in 2018 and headquartered in San Francisco, Day One Biopharmaceuticals completed its initial public offering in mid-2021. The company maintains research operations in San Diego and supports clinical development through collaboration with trial sites across North America and Europe. This geographic footprint enables Day One to enroll a diverse patient population and to expedite regulatory interactions with health authorities in key markets.

Day One’s leadership team is led by Chief Executive Officer David Meek, a seasoned biotech executive with more than two decades of experience in oncology drug development and commercialization. The management team also includes veterans from leading pharmaceutical and biotechnology companies, bringing deep expertise in clinical operations, regulatory affairs, and global commercial planning. Under this guidance, Day One is positioned to advance its pipeline toward potential regulatory approval and to deliver new treatment options for cancer patients.

Key Stats

• Today's Range: $6.88 to $7.24
• 50-Day Range: $6.16 to $7.93
• 52-Week Range: $6.08 to $16.76
• Volume: 1.61 million shs
• Average Volume: 1.15 million shs
• Market Capitalization: $728.78 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $29.00
• Consensus Rating: Buy

Day One Biopharmaceuticals Stock Analysis - MarketRank™

Day One Biopharmaceuticals scored higher than 39% of companies evaluated by MarketBeat, and ranked 719th out of 925 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 3.6 / 5
• Analyst Rating: Buy

Consensus Rating

Day One Biopharmaceuticals has received a consensus rating of Buy. The company's average rating score is 3.14, and is based on 6 buy ratings, no hold ratings, and no sell ratings.

Amount of Analyst Coverage

Day One Biopharmaceuticals has only been the subject of 2 research reports in the past 90 days.

Earnings and Valuation

• Score: 0.0 / 5
• Proj. Earnings Growth: Decreasing

Earnings Growth

Earnings for Day One Biopharmaceuticals are expected to decrease in the coming year, from ($0.72) to ($0.97) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Day One Biopharmaceuticals is -10.13, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Day One Biopharmaceuticals is -10.13, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Day One Biopharmaceuticals has a P/B Ratio of 1.44. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.

Short Interest

• Score: 2.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

16.89% of the float of Day One Biopharmaceuticals has been sold short.

Short Interest Ratio / Days to Cover

Day One Biopharmaceuticals has a short interest ratio ("days to cover") of 10, which indicates bearish sentiment.

Change versus previous month

Short interest in Day One Biopharmaceuticals has recently decreased by 32.06%, indicating that investor sentiment is improving significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Day One Biopharmaceuticals does not currently pay a dividend.

Dividend Growth

Day One Biopharmaceuticals does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

16.89% of the float of Day One Biopharmaceuticals has been sold short.

Short Interest Ratio / Days to Cover

Day One Biopharmaceuticals has a short interest ratio ("days to cover") of 10, which indicates bearish sentiment.

Change versus previous month

Short interest in Day One Biopharmaceuticals has recently decreased by 32.06%, indicating that investor sentiment is improving significantly.

News and Social Media

• Score: 0.6 / 5
• News Sentiment: 0.00

News Coverage This Week

MarketBeat has tracked 2 news articles for Day One Biopharmaceuticals this week, compared to 4 articles on an average week.

Search Interest

Only 1 people have searched for DAWN on MarketBeat in the last 30 days. This is a decrease of -86% compared to the previous 30 days.

MarketBeat Follows

2 people have added Day One Biopharmaceuticals to their MarketBeat watchlist in the last 30 days. This is an increase of 100% compared to the previous 30 days.

Company Ownership

• Score: 2.5 / 5
• Insider Trading: Selling Shares

Insider Buying vs. Insider Selling

In the past three months, Day One Biopharmaceuticals insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $167,298.00 in company stock.

Percentage Held by Insiders

Only 6.20% of the stock of Day One Biopharmaceuticals is held by insiders.

Percentage Held by Institutions

87.95% of the stock of Day One Biopharmaceuticals is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

DAWN Stock Analysis - Frequently Asked Questions

How have DAWN shares performed this year?

Day One Biopharmaceuticals' stock was trading at $12.67 at the beginning of 2025. Since then, DAWN stock has decreased by 43.3% and is now trading at $7.19.

How were Day One Biopharmaceuticals' earnings last quarter?

Day One Biopharmaceuticals, Inc. (NASDAQ:DAWN) released its earnings results on Tuesday, May, 6th. The company reported ($0.35) earnings per share (EPS) for the quarter, beating the consensus estimate of ($0.46) by $0.11. The business had revenue of $30.76 million for the quarter, compared to analyst estimates of $30.28 million. Day One Biopharmaceuticals had a negative net margin of 42.66% and a negative trailing twelve-month return on equity of 14.98%.
Read the conference call transcript.

When did Day One Biopharmaceuticals IPO?

Day One Biopharmaceuticals (DAWN) raised $126 million in an initial public offering (IPO) on Thursday, May 27th 2021. The company issued 8,400,000 shares at $14.00-$16.00 per share. J.P. Morgan, Cowen and Piper Sandler served as the underwriters for the IPO and Wedbush PacGrow was co-manager.

How do I buy shares of Day One Biopharmaceuticals?

Shares of DAWN stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Day One Biopharmaceuticals own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Day One Biopharmaceuticals investors own include Invesco QQQ (QQQ), SPDR S&P 500 ETF Trust (SPY), SPDR Dow Jones Industrial Average ETF Trust (DIA), NVIDIA (NVDA), Advanced Micro Devices (AMD), Meta Platforms (META) and Tesla (TSLA).

Company Calendar

• Last Earnings: 5/06/2025
• Today: 7/10/2025
• Next Earnings (Estimated): 7/29/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:DAWN
• CIK: 1845337
• Web: dayonebio.com
• Phone: 650-484-0899
• Fax: N/A
• Employees: 60
• Year Founded: N/A

Price Target and Rating

• Average Price Target for Day One Biopharmaceuticals: $29.00
• High Price Target: $36.00
• Low Price Target: $25.00
• Potential Upside/Downside: +303.3%
• Consensus Rating: Buy
• Rating Score (0-4): 3.14
• Research Coverage: 7 Analysts

Profitability

• EPS (Trailing Twelve Months): ($0.71)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$95.50 million
• Net Margins: -42.66%
• Pretax Margin: -38.25%
• Return on Equity: -14.98%
• Return on Assets: -13.04%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 10.62
• Quick Ratio: 10.55

Sales & Book Value

• Annual Sales: $131.16 million
• Price / Sales: 5.56
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $4.99 per share
• Price / Book: 1.44

Miscellaneous

• Outstanding Shares: 101,360,000
• Free Float: 95,078,000
• Market Cap: $728.78 million
• Optionable: Optionable
• Beta: -1.27