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Trustees picked by DeSantis may change progressive college
Qatar replaces Russian company in Lebanon gas exploration
The Next Big Crisis Is Here (Ad)
France must raise pension age to 64, prime minister says
Elon Musk's mysterious ways on display in Tesla tweet trial
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Biden, McCarthy to discuss debt limit in talks on Wednesday
Dutch firm: US, allies near deal to limit chip tech to China
S&P 500   3,852.36
DOW   32,920.46
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Inflation Tips for Startups – Top 11
Is This The End of Capitalism? (Ad)
Trustees picked by DeSantis may change progressive college
Qatar replaces Russian company in Lebanon gas exploration
The Next Big Crisis Is Here (Ad)
France must raise pension age to 64, prime minister says
Elon Musk's mysterious ways on display in Tesla tweet trial
The Next Big Crisis Is Here (Ad)
Biden, McCarthy to discuss debt limit in talks on Wednesday
Dutch firm: US, allies near deal to limit chip tech to China
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DOW   32,920.46
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Is This The End of Capitalism? (Ad)
Trustees picked by DeSantis may change progressive college
Qatar replaces Russian company in Lebanon gas exploration
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France must raise pension age to 64, prime minister says
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Biden, McCarthy to discuss debt limit in talks on Wednesday
Dutch firm: US, allies near deal to limit chip tech to China

Is the Pain Over for Baudax Bio Investors after a 70% Spike?

Key Points

  • Baudax Bio gapped after announcing a positive interim Phase 2 clinical trial outcome for BX100, its neuromuscular blocking agent used in patients undergoing elective surgery.
  • The Company is recovering from discontinuing its prior failed pain drug Anjeso and laid off the sales team at the end of 2022.
  • Average daily trading volume is just under 250,000 shares a day.
  • BXRX shares have a razor-thin float of around 500,000 and a 12% short interest.
  • 5 stocks we like better than Baudax Bio

Is the Pain Over for Baudax Bio Investors after a 70% Spike?

Baudax Bio (NASDAQ: BXRX) shares spiked as much as 70% on its announcement of positive interim phase 2 clinical trials for its pain medicine BX1000. While the interim positive outcome is based on a 20-patient group, it expects to complete the phase 2 trial with 80 patients by the end of the first quarter of 2023.

The dramatic spike in the stock resulted from the massive volume, which surged to over 45 million shares on the announcement on Jan. 24, 2023. The average daily trading volume is usually around 242,000 shares. The stock has a 52-week high of $306.46 and a low of $1.55. This stock is a high-risk and highly volatile speculation play for anyone considering it.

What Do They Do?

Baudax Bio is a Pennsylvania-based developmental-stage biotechnology firm with approximately 80 employees. The Company did just over $1.3 million in revenues with over ($22,500,000) in net losses.

The Company has a single FDA-approved medicine Anjeso, which it discontinued at the end of 2022. It has multiple neuromuscular blocking agents (NMBA) in various stages of clinical studies.

Some of the larger pharmaceutical companies that make NMBA include AbbVie Inc. (NYSE: ABBV), Pfizer (NYSE: PFE), Allergan PLC (NYSE: AGN), and Merck & Co. Inc (NYSE: MRK). These are all potential suitors or partners if the BX clinical trials are positive.


Troubled History of Commercialization

Baudax has yet to be very successful in commercializing its products. In an SEC filing on Dec. 30, 2022, the Company terminated its sales personnel for Anjeso, its first commercial product for pain. The FDA approved Anjeso (Meloxicam) on Feb. 20, 2020, for injection to manage severe pain alone or in conjunction with other non-NSAID analgesics.

The Company said that although it has discontinued producing the drug, it will continue to evaluate alternative ways to monetize Anjeso both in the U.S. and internationally.

They also mentioned they've started enrolling patients in the phase 2 trial of BX1000, an intermediate NMBA for pain. The clinical trial involves patients undergoing abdominal surgical conditions. The Company expects to complete enrollment in the study by the end of Q1 2023, which an interim analyst before that. 

Positive Interim Phase 2 Trial Outcomes for BX1000

Fast forward to Jan. 24, 2023, Baudax posted a positive outcome in its phase 2 trial of BX1000. The interim analysis focused on assessing the intubating conditions of 20 patients after using BX1000. It noted that all patients had good or excellent intubating conditions at 60 seconds with no severe or adverse side effects, and the drug was well tolerated.

The full study intends to evaluate NMB in 80 adults undergoing elective surgery using total intravenous anesthesia.

CEO Comments

Baudax Bio CEO Gerri Harwood commented, “We are encouraged by the results of the first interim analysis of the BX1000 Phase II surgery trial. We believe the use of BX1000, combined with our reversal agent, BX3000, could make for precise control of timing under neuromuscular paralysis for surgical patients, which could result in time and cost savings for patients and hospitals alike. We look forward to completing enrollment in the study in Q1 and sharing the topline results for the study in April 2023. The Company will continue its study through completion with topline results due out in April."

BX2000 and BX3000

Its BX- series of non-opioid medicines are designed to treat pain during elective surgeries. It also has intranasal Dex-IN (Dexmedetomidine) currently in phase 2 active clinical trials for peri-procedural and cancer breakthrough pain. They are scheduled to report fiscal Q4 2023 earnings in May 2023.

The Company also has BX2000, an ultra-short-acting NMBS, in a dose escalation study with healthy volunteers, which it expects to complete in 2023. Its BX3000 is currently in pre-clinical studies. If the studies are positive, there is speculation that the Company may be acquired by a more significant pharmaceutical player or sign a licensing agreement.

Based on its history, the Company isn't able to commercialize its medicine on its own. The ultra-thin float has made it a super volatile stock only suitable for the most risk-averse speculators looking for a lotto ticket-like speculation. 

Is the Pain Over for Baudax Bio Investors after a 70% Spike?

Daily Descending Triangle Breakout

BXRX shares have been in a bearish daily descending triangle that started in December 2022 as shares fell from a high of $7.64 on Nov. 30, 2022, to hit a low of $1.55 on Dec. 19, 2022, just before the filing with the SEC regarding its discontinuance of Anjeso drug. Shares coiled on the daily stochastic to peak at $4.84 after trigging the daily market structure low (MSL) buy signal on the breakout through $2.75.

The daily 20-period exponential moving average (EMA) is flat but turning at $3.35 as the daily 50-period MA sits at $3.92. Shares started to flatline but held above the descending triangle downtrend line at $3.30 before the phase 2 news spiking it up to a high of $6.89 before pulling back. Pullback support levels sit at

Should you invest $1,000 in Baudax Bio right now?

Before you consider Baudax Bio, you'll want to hear this.

MarketBeat keeps track of Wall Street's top-rated and best performing research analysts and the stocks they recommend to their clients on a daily basis. MarketBeat has identified the five stocks that top analysts are quietly whispering to their clients to buy now before the broader market catches on... and Baudax Bio wasn't on the list.

While Baudax Bio currently has a "Hold" rating among analysts, top-rated analysts believe these five stocks are better buys.

View The Five Stocks Here

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Companies Mentioned in This Article

CompanyMarketRank™Current PricePrice ChangeDividend YieldP/E RatioConsensus RatingConsensus Price Target
Baudax Bio (BXRX)
1.6567 of 5 stars
$3.02-1.9%N/A0.02Hold$1.00
AbbVie (ABBV)
2.6986 of 5 stars
$146.28-0.8%4.05%19.53Hold$160.56
Pfizer (PFE)
3.0797 of 5 stars
$43.79-1.0%3.75%8.42Hold$52.33
Allergan (AGN)
0 of 5 stars
$0.00-100.0%-12.07N/AN/A
Merck & Co., Inc. (MRK)
2.8822 of 5 stars
$105.38-1.4%2.77%17.53Moderate Buy$113.83
Compare These Stocks  Add These Stocks to My Watchlist 

Jea Yu

About Jea Yu

Contributing Author: Trading Strategies

With over 20 years of active participation and analysis of the US equities, options and futures markets, Mr. Yu brings fresh insights into the workings of the financial markets. He has published four books by esteemed publishers McGraw-Hill, John Wiley & Sons, Marketplace Books and Bloomberg Press. His brainchild, the Underground Trader, was voted Forbes Best of the Web for four consecutive years under the active trader category. He has been a featured speaker all over the country at various expos and seminars who enjoys a standing-room-only reception in the largest convention halls from New York to Las Vegas. He has been quoted and featured in USA Today, Wall Street Journal, Traders Magazine and the Financial Times and various trade publications like Stocks & Commodities, Active Trader and Online Investor. Mr. Yu has a B.A. in Liberal Arts and minor in Business Administration from the University of Maryland.
Contact Jea Yu via email at JeaYu21@gmail.com.

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