Apellis Pharmaceuticals (APLS) Institutional Ownership $28.22 +0.29 (+1.04%) Closing price 08/27/2025 04:00 PM EasternExtended Trading$27.96 -0.27 (-0.94%) As of 08:00 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Ownership Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock Institutional Ownership Changes (13F Filings) for Apellis Pharmaceuticals (NASDAQ:APLS)CurrentInstitutional OwnershipPercentage96.29%Number ofInstitutional Buyers(last 12 months)172TotalInstitutional Inflows(last 12 months)$1.20BNumber ofInstitutional Sellers(last 12 months)97TotalInstitutional Outflows(last 12 months)$545.64M Get APLS Insider Trade Alerts Want to know when executives and insiders are buying or selling Apellis Pharmaceuticals stock? Sign up for InsiderTrades.com's daily newsletter to get the latest insider transactions delivered to your inbox daily. 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Skip Chart & View Institutional Buying and Selling Data APLS Institutional Buying and Selling by Quarter Apellis Pharmaceuticals Major Shareholders & Ownership History Export to ExcelReporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails8/27/2025 Squarepoint Ops LLC329,392$5.70M0.0%-25.6%0.261% 8/18/2025 Hudson Bay Capital Management LP475,000$8.22M0.0%+52.9%0.376% 8/16/2025 Headlands Technologies LLC6,892$119K0.0%+748.8%0.005% 8/15/2025 Exome Asset Management LLC98,600$1.71M0.9%N/A0.078% 8/15/2025 E Fund Management Co. Ltd.16,057$278K0.0%-4.6%0.013% 8/15/2025 Voleon Capital Management LP43,139$747K0.0%+42.9%0.034% 8/15/2025 Two Sigma Securities LLC21,168$366K0.0%N/A0.017% 8/15/2025 Rafferty Asset Management LLC143,852$2.49M0.0%-20.1%0.114% 8/15/2025 Octagon Capital Advisors LP903,500$15.64M3.4%-56.9%0.715% 8/15/2025 HRT Financial LP107,200$1.86M0.0%N/A0.085% Get the Latest News and Ratings for APLS and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Apellis Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. 8/15/2025 Hudson Bay Capital Management LP475,000$8.22M0.0%+52.9%0.376% 8/15/2025 Engineers Gate Manager LP58,718$1.02M0.0%+39.2%0.046% 8/15/2025 BNP Paribas Financial Markets1,298,459$22.48M0.0%+16.9%1.028% 8/15/2025 Braidwell LP1,121,034$19.41M0.7%-32.2%0.888% 8/15/2025 Bank of America Corp DE2,426,628$42.01M0.0%-22.5%1.921% 8/15/2025 683 Capital Management LLC410,000$7.10M0.5%+23.1%0.325% 8/15/2025 Ameriprise Financial Inc.750,161$12.99M0.0%+60.8%0.594% 8/15/2025 AQR Capital Management LLC5,976,414$103.45M0.1%+46.6%4.732% 8/14/2025 PDT Partners LLC160,058$2.77M0.2%-18.0%0.127% 8/14/2025 California State Teachers Retirement System87,929$1.52M0.0%+47.1%0.070% 8/14/2025 Raymond James Financial Inc.74,466$1.29M0.0%+43.3%0.059% 8/14/2025 Canada Pension Plan Investment Board336,800$5.83M0.0%-67.9%0.267% 8/14/2025 Camber Capital Management LP850,000$14.71M1.4%N/A0.673% 8/14/2025 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.40,984$710K0.0%+38.7%0.032% 8/14/2025 Ieq Capital LLC346,923$6.01M0.0%+18.9%0.275% 8/14/2025 Treasurer of the State of North Carolina50,358$872K0.0%+2.8%0.040% 8/14/2025 The Manufacturers Life Insurance Company 21,973$380K0.0%-11.9%0.017% 8/14/2025 Squarepoint Ops LLC329,392$5.70M0.0%-25.6%0.261% 8/14/2025 Sei Investments Co.22,359$387K0.0%N/A0.018% 8/14/2025 HighVista Strategies LLC86,663$1.50M0.6%-20.3%0.069% 8/14/2025 Natixis90,666$1.57M0.0%-86.2%0.072% 8/14/2025 Ossiam555,953$9.62M0.1%N/A0.440% 8/14/2025 Bank of Nova Scotia594,812$10.30M0.0%N/A0.471% 8/14/2025 California Public Employees Retirement System134,637$2.33M0.0%+6.3%0.107% 8/14/2025 Cerity Partners LLC114,745$1.99M0.0%+110.8%0.091% 8/13/2025 Jump Financial LLC558,668$9.67M0.1%+110.3%0.442% 8/13/2025 Amundi1,604,105$28.59M0.0%+386.7%1.270% 8/13/2025 Marshall Wace LLP2,704,837$46.82M0.1%+11,373.8%2.142% 8/13/2025 First Trust Advisors LP26,538$459K0.0%-86.7%0.021% 8/13/2025 EverSource Wealth Advisors LLC5,429$94K0.0%+338.5%0.004% Market Panic: Trump Just Dropped a Bomb on Your Stocks (Ad)tock Market Panic: Trump Just Dropped a Bomb on Your Stocks The market is in freefall—and Trump's new tariffs just lit the fuse. 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Get the FREE Guide Before Markets Open Tomorrow8/13/2025 Invesco Ltd.166,135$2.88M0.0%-74.1%0.132% 8/13/2025 Edgestream Partners L.P.218,392$3.78M0.1%-9.5%0.173% 8/13/2025 Wealthedge Investment Advisors LLC38,572$668K0.3%N/A0.031% 8/13/2025 New York State Common Retirement Fund58,879$1.02M0.0%+20.6%0.047% 8/13/2025 Schroder Investment Management Group485,615$8.41M0.0%+91.9%0.385% 8/13/2025 Virtus Investment Advisers LLC23,073$399K0.1%+110.4%0.018% 8/13/2025 Norges Bank2,367,224$40.98M0.0%N/A1.874% 8/13/2025 Quadrature Capital Ltd16,798$291K0.0%N/A0.013% 8/13/2025 Hsbc Holdings PLC57,898$1.00M0.0%+131.6%0.046% 8/13/2025 Russell Investments Group Ltd.9,925$172K0.0%-74.5%0.008% 8/13/2025 Rhenman & Partners Asset Management AB93,250$1.61M0.2%+230.1%0.074% 8/12/2025 Steward Partners Investment Advisory LLC140,975$2.44M0.0%+15.4%0.112% 8/12/2025 Prudential Financial Inc.154,010$2.67M0.0%-29.3%0.122% 8/12/2025 Rhumbline Advisers122,002$2.11M0.0%-2.0%0.097% 8/12/2025 Legal & General Group Plc96,050$1.66M0.0%+21.5%0.076% 8/12/2025 JPMorgan Chase & Co.234,801$4.06M0.0%-67.6%0.186% 8/12/2025 Swiss National Bank143,800$2.49M0.0%+8.4%0.114% 8/11/2025 Universal Beteiligungs und Servicegesellschaft mbH25,273$437K0.0%+56.4%0.020% 8/8/2025 Creative Planning21,838$378K0.0%N/A0.017% 8/8/2025 SG Americas Securities LLC45,103$781K0.0%-87.7%0.036% 8/8/2025 Police & Firemen s Retirement System of New Jersey40,954$709K0.0%+6.2%0.032% 8/8/2025 Geode Capital Management LLC1,995,271$34.55M0.0%+2.3%1.580% 8/8/2025 PNC Financial Services Group Inc.58,856$1.02M0.0%+0.8%0.047% 8/8/2025 KBC Group NV2,313$40K0.0%-39.9%0.002% 8/7/2025 Profund Advisors LLC28,676$496K0.0%-19.6%0.023% 8/7/2025 Connor Clark & Lunn Investment Management Ltd.118,724$2.06M0.0%-10.0%0.094% 8/6/2025 Fox Run Management L.L.C.13,967$242K0.0%-11.1%0.011% 8/6/2025 Savant Capital LLC99,183$1.72M0.0%+124.2%0.079% 8/6/2025 Phocas Financial Corp.71,599$1.24M0.2%N/A0.057% 8/6/2025 EFG Asset Management North America Corp.105,024$1.82M0.3%+166.8%0.083% 8/5/2025 Corton Capital Inc.21,011$364K0.4%N/A0.017% 8/5/2025 Bank of Montreal Can159,613$2.76M0.0%+0.7%0.126% 8/4/2025 Amalgamated Bank8,111$140K0.0%+12.0%0.006% 8/1/2025 Jennison Associates LLC2,661,823$46.08M0.0%+7.4%2.118% 8/1/2025 Teacher Retirement System of Texas20,287$351K0.0%+9.9%0.016% 8/1/2025 Y Intercept Hong Kong Ltd164,275$2.84M0.1%+455.4%0.131% 7/31/2025 Brighton Jones LLC16,539$286K0.0%N/A0.013% 7/31/2025 Focus Partners Advisor Solutions LLC24,350$422K0.0%+47.0%0.019% 7/31/2025 AlphaQuest LLC21,240$368K0.0%-62.1%0.017% 7/30/2025 Bleakley Financial Group LLC77,088$1.33M0.0%+5.4%0.061% 7/29/2025 VIRGINIA RETIREMENT SYSTEMS ET Al27,665$479K0.0%N/A0.022% 7/28/2025 Bayforest Capital Ltd56,639$980K0.4%+8.2%0.045% 7/25/2025 CWM LLC127,584$2.21M0.0%+29.8%0.102% 7/24/2025 Eastern Bank10,000$173K0.0%-53.5%0.008% 7/23/2025 KLP Kapitalforvaltning AS15,600$270K0.0%+20.0%0.012% 7/22/2025 Duncan Williams Asset Management LLC17,005$294K0.0%-19.5%0.014% 7/21/2025 111 Capital12,400$215K0.0%-26.3%0.010% 7/21/2025 Mirae Asset Global Investments Co. Ltd.4,855$84K0.0%+15.6%0.004% 7/21/2025 J. Safra Sarasin Holding AG115,684$2.00M0.0%+145.6%0.092% 7/10/2025 Wealth Enhancement Advisory Services LLC100,666$1.84M0.0%+43.5%0.080% When the levee breaks (Ad)The U.S. Treasury just confirmed it plans to borrow $1.01 trillion this quarter—nearly double what was projected. According to Porter Stansberry, this is panic-level borrowing… and a clear sign we’re nearing America’s financial breaking point. In his latest emergency briefing, Porter outlines why the cracks in our system are widening fast—and how Trump’s policies may be accelerating the collapse. More importantly, he reveals three moves you can make now to protect and potentially grow your wealth before the levee breaks.Click here to watch the urgent broadcast and get ahead of what’s coming.7/9/2025 Pallas Capital Advisors LLC54,849$949K0.0%+29.0%0.044% 7/8/2025 Parallel Advisors LLC1,924$33K0.0%+80.0%0.002% 6/27/2025 Goldman Sachs Group Inc.307,709$6.73M0.0%+26.6%0.245% 6/18/2025 Voya Investment Management LLC125,401$2.74M0.0%+1.8%0.100% 5/29/2025 Rhumbline Advisers124,454$2.72M0.0%-0.9%0.099% 5/21/2025 Acadian Asset Management LLC23,976$522K0.0%+1,146.2%0.019% 5/20/2025 Focus Partners Wealth21,883$479K0.0%+118.4%0.017% 5/19/2025 Bayforest Capital Ltd52,338$1.15M0.5%+431.9%0.042% 5/19/2025 UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC222,634$4.87M0.0%+4.6%0.177% 5/16/2025 Woodline Partners LP218,850$4.79M0.0%+15.5%0.174% (Data available from 1/1/2016 forward) APLS Institutional Ownership - Frequently Asked Questions Who are the largest shareholders of APLS shares? During the previous two years, 284 institutional investors and hedge funds held shares of Apellis Pharmaceuticals. The most heavily invested institutionals were Avoro Capital Advisors LLC ($390.01M), EcoR1 Capital LLC ($260.16M), Vanguard Group Inc. ($221.55M), Deep Track Capital LP ($136.41M), State Street Corp ($116.54M), AQR Capital Management LLC ($103.45M), and FMR LLC ($83.64M).Learn more on Apellis Pharmaceuticals' institutional investors. What percentage of Apellis Pharmaceuticals' stock is owned by institutional investors? 96.29% of Apellis Pharmaceuticals' stock is owned by institutional investors. Learn more on APLS's institutional investor holdings. Which institutional investors have been buying Apellis Pharmaceuticals' stock? Of the 239 institutional investors that purchased Apellis Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: AQR Capital Management LLC ($5.35M), Norges Bank ($4.40M), Assenagon Asset Management S.A. ($3.10M), Marshall Wace LLP ($2.74M), Jennison Associates LLC ($2.70M), Braidwell LP ($2.51M), and Toronto Dominion Bank ($1.97M). How much institutional buying is happening at Apellis Pharmaceuticals? Institutional investors have bought a total of 46,083,336 shares in the last 24 months. This purchase volume represents approximately $1.20B in transactions. Which of Apellis Pharmaceuticals' major shareholders have been selling company stock? Of the 97 institutional investors that sold Apellis Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: T. Rowe Price Investment Management Inc. ($2.94M), Assenagon Asset Management S.A. ($2.11M), Octagon Capital Advisors LP ($2.10M), Jennison Associates LLC ($2.05M), Braidwell LP ($2.00M), Royal Bank of Canada ($723.89K), and Canada Pension Plan Investment Board ($711.90K). How much institutional selling is happening at Apellis Pharmaceuticals? Institutional investors have sold a total of 21,437,071 shares in the last 24 months. This volume of shares sold represents approximately $545.64M in transactions. Related Companies VTRS Major Shareholders ASND Major Shareholders RDY Major Shareholders QGEN Major Shareholders MRNA Major Shareholders BBIO Major Shareholders VRNA Major Shareholders ELAN Major Shareholders BPMC Major Shareholders ROIV Major Shareholders This page (NASDAQ:APLS) was last updated on 8/28/2025 by MarketBeat.com Staff From Our PartnersBuffett, Gates and Bezos Quietly Dumping Stocks—Here's WhyImagine a bull market so powerful, every single investor became a millionaire. 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