AstraZeneca (AZN) News Today $79.56 -1.54 (-1.90%) Closing price 09/12/2025 04:00 PM EasternExtended Trading$79.68 +0.13 (+0.16%) As of 09/12/2025 07:44 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Headlines Stock AnalysisAnalyst ForecastsChartCompetitorsDividendEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Why Is AstraZeneca Down Today?Toggle Visibility of Why Is AstraZeneca Down Today?AstraZeneca PLC (NASDAQ:AZN) shares are trading lower amid investor caution. Key news driving sentiment: Positive Sentiment: AstraZeneca announces EMA validation for its Enhertu marketing authorization in the EU, advancing a key cancer‐therapy milestone. AstraZeneca announces EMA validation for Enhertu marketing authorization Positive Sentiment: Zacks Research analysts boosted AstraZeneca’s earnings forecasts across multiple periods—raising Q2 2027 EPS to $1.39 (from $1.37), Q1 2027 to $1.28 (from $1.27), Q2 2026 to $1.23 (from $1.22), FY2027 to $5.70 (from $5.62) and FY2026 to $5.03 (from $4.97). Free Report Negative Sentiment: AstraZeneca paused a planned £200 million ($270 million) expansion of its Cambridge research site, highlighting growing UK pharma‐government tensions over pricing and competitiveness. Exclusive: AstraZeneca pauses $270 million investment in Britain Negative Sentiment: Short interest surged 25.5% in August to 7.77 million shares, signaling increased bearish bets; the current days-to-cover ratio stands at 1.8. Posted 1+ days agoAI Generated. May Contain Errors. AZN Latest News All Sources Trusted Sources MarketBeat Barchart Benzinga Bloomberg GlobeNewswire GuruFocus MarketWatch Motley Fool NASDAQ PR Newswire Reuters Seeking Alpha TalkMarkets The Street TipRanks The Wall Street Journal Wall Street Zen Yahoo Finance Source Sentiment refers to the positivity or negativity of each headline according to our language processing algorithm. Sentiment All Sentiments Very Positive Positive Neutral Negative Very Negative Most Recent September 2025 August 2025 July 2025 June 2025 May 2025 April 2025 March 2025 February 2025 January 2025 December 2024 November 2024 October 2024 September 2024 August 2024 July 2024 June 2024 May 2024 April 2024 March 2024 February 2024 January 2024 December 2023 November 2023 October 2023 September 2023 August 2023 July 2023 June 2023 May 2023 April 2023 March 2023 February 2023 January 2023 December 2022 November 2022 October 2022 Time Period Foresight Group Ltd Liability Partnership Invests $16.01 Million in AstraZeneca PLC $AZNSeptember 13 at 6:44 AM | marketbeat.comZacks Research Expects Increased Earnings for AstraZenecaSeptember 13 at 2:43 AM | americanbankingnews.comAstraZeneca pauses planned $270M investment in Britain, Reuters reportsSeptember 12 at 4:31 PM | msn.comAstraZeneca (LSE:AZN) Advances Cancer Drug In EU With EMA Application ValidationSeptember 12 at 4:31 PM | finance.yahoo.comExclusive: AstraZeneca pauses $270 million investment in BritainSeptember 12 at 12:38 PM | reuters.comSCS Capital Management LLC Makes New $3.07 Million Investment in AstraZeneca PLC $AZNSeptember 12 at 7:02 AM | marketbeat.comAscent Group LLC Invests $1.18 Million in AstraZeneca PLC $AZNSeptember 12 at 6:10 AM | marketbeat.comAstraZeneca announces EMA validation for Enhertu marketing authorizationSeptember 11 at 8:46 AM | msn.comExome Asset Management LLC Takes $2.39 Million Position in AstraZeneca PLC $AZNSeptember 11 at 6:17 AM | marketbeat.comFred Alger Management LLC Raises Position in AstraZeneca PLC $AZNSeptember 11 at 4:55 AM | marketbeat.comFDA expands approval of AstraZeneca’s KoselugoSeptember 10, 2025 | msn.comMerck to cancel London drug research center, lay off scientists : FTSeptember 10, 2025 | msn.comFDA Expands Approval For AstraZeneca's Drug For Pediatric Patients With Rare Type Of CancerSeptember 10, 2025 | finance.yahoo.comCoppell Advisory Solutions LLC Sells 9,113 Shares of AstraZeneca PLC $AZNSeptember 10, 2025 | marketbeat.comPolar Asset Management Partners Inc. Lowers Stock Holdings in AstraZeneca PLC $AZNSeptember 9, 2025 | marketbeat.comAstraZeneca PLC $AZN Shares Purchased by Nissay Asset Management Corp Japan ADVSeptember 9, 2025 | marketbeat.comMIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. Purchases 30,452 Shares of AstraZeneca PLC $AZNSeptember 9, 2025 | marketbeat.comAstraZeneca PLC $AZN Shares Sold by Parkwood LLCSeptember 8, 2025 | marketbeat.comThe FTSE 100’s largest company could surpass a £200bn market valuation this yearSeptember 8, 2025 | uk.finance.yahoo.comKepler Capital Sticks to Its Hold Rating for AstraZeneca (AZN)September 7, 2025 | theglobeandmail.comClark Capital Management Group Inc. Increases Stock Holdings in AstraZeneca PLC $AZNSeptember 7, 2025 | marketbeat.comCuri RMB Capital LLC Invests $6.45 Million in AstraZeneca PLC $AZNSeptember 7, 2025 | marketbeat.comAlliancebernstein L.P. Sells 914,344 Shares of AstraZeneca PLC $AZNSeptember 7, 2025 | marketbeat.comCinctive Capital Management LP Increases Position in AstraZeneca PLC $AZNSeptember 6, 2025 | marketbeat.comAlyeska Investment Group L.P. Has $66.52 Million Stock Position in AstraZeneca PLC $AZNSeptember 6, 2025 | marketbeat.comAprio Wealth Management LLC Increases Holdings in AstraZeneca PLC $AZNSeptember 6, 2025 | marketbeat.comAdage Capital Partners GP L.L.C. Buys 293,833 Shares of AstraZeneca PLC $AZNSeptember 6, 2025 | marketbeat.comTrexquant Investment LP Takes Position in AstraZeneca PLC $AZNSeptember 6, 2025 | marketbeat.comJump Financial LLC Trims Stock Holdings in AstraZeneca PLC $AZNSeptember 6, 2025 | marketbeat.comBanque Transatlantique SA Has $9.66 Million Stake in AstraZeneca PLC $AZNSeptember 5, 2025 | marketbeat.comFederation des caisses Desjardins du Quebec Increases Holdings in AstraZeneca PLC $AZNSeptember 5, 2025 | marketbeat.comRoyal Bank of Canada Boosts Stock Position in AstraZeneca PLC $AZNSeptember 4, 2025 | marketbeat.comAmerican Century Focused International Growth Fund Q2 2025 CommentarySeptember 4, 2025 | seekingalpha.comGlobal drugmakers rush to boost US presence as tariff threat loomsSeptember 3, 2025 | reuters.comCubist Systematic Strategies LLC Has $17.25 Million Position in AstraZeneca PLC $AZNSeptember 3, 2025 | marketbeat.comAstraZeneca PLC $AZN Holdings Lowered by Armistice Capital LLCSeptember 3, 2025 | marketbeat.comDRW Securities LLC Increases Position in AstraZeneca PLC $AZNSeptember 3, 2025 | marketbeat.comFlputnam Investment Management Co. Grows Stock Position in AstraZeneca PLC $AZNSeptember 2, 2025 | marketbeat.comPoint72 Europe London LLP Purchases New Shares in AstraZeneca PLC $AZNSeptember 2, 2025 | marketbeat.comAstraZeneca: Buy This Pharma Star Now For Upside PotentialSeptember 2, 2025 | seekingalpha.comVident Advisory LLC Raises Stock Position in AstraZeneca PLC $AZNSeptember 1, 2025 | marketbeat.comOLD Mission Capital LLC Raises Stock Position in AstraZeneca PLC $AZNAugust 31, 2025 | marketbeat.comParnassus Investments LLC Has $90.02 Million Stock Holdings in AstraZeneca PLC $AZNAugust 31, 2025 | marketbeat.comAstraZeneca PLC $AZN Shares Bought by Clayton Partners LLCAugust 31, 2025 | marketbeat.comIron Triangle Partners LP Makes New $27.66 Million Investment in AstraZeneca PLC $AZNAugust 31, 2025 | marketbeat.comItau Unibanco Holding S.A. Lowers Stock Position in AstraZeneca PLC $AZNAugust 31, 2025 | marketbeat.comAstraZeneca is said to seek approval for antihypertensive this yearAugust 30, 2025 | seekingalpha.comAstraZeneca's $80 Billion Ambition Just Got A Big Infusion With New Hypertension ResultsAugust 30, 2025 | investors.comAstraZeneca to seek approval for blood pressure drug by year-endAugust 30, 2025 | reuters.comOarsman Capital Inc. Has $1.74 Million Stock Position in AstraZeneca PLC $AZNAugust 30, 2025 | marketbeat.com Get AstraZeneca News Delivered to You Automatically Sign up to receive the latest news and ratings for AZN and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. 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This chart compares the number of articles about this company in the last seven days compared with the average number of articles about this company on a typical week. AZN Articles This Week▼3124▲AZN Articles Average Week Get the Latest News and Ratings for AZN and Related Stocks Enter your email address to receive the latest news and analysts' ratings for AstraZeneca and its competitors. Sign Up View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. 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