COMPASS Pathways (CMPS) Stock Price, News & Analysis

Company Overview

COMPASS Pathways (NASDAQ: CMPS) is a clinical-stage biotechnology company focused on the development and commercialization of psilocybin therapy for mental health disorders. Founded in 2016 and headquartered in London with additional offices in the United States, COMPASS Pathways is pioneering the use of synthetic psilocybin combined with psychotherapy to address treatment-resistant depression. The company’s flagship program is a Phase IIb clinical trial evaluating COMP360, its proprietary psilocybin formulation, which has received Breakthrough Therapy designation from the U.S. Food and Drug Administration.

In addition to its lead depression program, COMPASS Pathways is exploring broader applications of psychedelic-assisted therapies in areas such as anorexia nervosa and other mood disorders. The company has built a scalable manufacturing process for synthetic psilocybin and established a network of trained therapists and research sites across Europe and North America. COMPASS also leverages digital tools to capture patient-reported outcomes and physiological data, supporting personalized treatment protocols and enhancing safety monitoring throughout clinical studies.

Since its initial public offering in September 2020, COMPASS Pathways has advanced its pipeline through rigorous clinical partnerships and academic collaborations. The leadership team is led by co-founder and CEO George Goldsmith, who has guided the company through regulatory milestones and strategic alliances. With a board of directors comprising experts in neuroscience, clinical research, and life sciences commercialization, COMPASS remains committed to transforming the treatment paradigm for mental health by combining innovative science, patient-centered care, and robust regulatory engagement.

Key Stats

• Today's Range: $5.15 to $5.29
• 50-Day Range: $3.31 to $5.24
• 52-Week Range: $2.25 to $7.53
• Volume: 703,769 shs
• Average Volume: 1.76 million shs
• Market Capitalization: $498.89 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $16.29
• Consensus Rating: Moderate Buy

COMPASS Pathways Stock Analysis - MarketRank™

COMPASS Pathways scored higher than 65% of companies evaluated by MarketBeat, and ranked 380th out of 954 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 4.0 / 5
• Analyst Rating: Moderate Buy

Consensus Rating

COMPASS Pathways has received a consensus rating of Moderate Buy. The company's average rating score is 2.86, and is based on 6 buy ratings, 1 hold rating, and no sell ratings.

Upside Potential

COMPASS Pathways has a consensus price target of $16.29, representing about 213.2% upside from its current price of $5.20.

Amount of Analyst Coverage

COMPASS Pathways has only been the subject of 3 research reports in the past 90 days.

Earnings and Valuation

• Score: 0.6 / 5
• Proj. Earnings Growth: Growing

Earnings Growth

Earnings for COMPASS Pathways are expected to grow in the coming year, from ($2.33) to ($1.98) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of COMPASS Pathways is -2.83, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of COMPASS Pathways is -2.83, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

COMPASS Pathways has a P/B Ratio of 2.30. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.

Short Interest

• Score: 4.0 / 5
• Short Interest Level: Healthy

Percentage of Shares Shorted

8.44% of the float of COMPASS Pathways has been sold short.

Short Interest Ratio / Days to Cover

COMPASS Pathways has a short interest ratio ("days to cover") of 2.6, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in COMPASS Pathways has recently decreased by 9.11%, indicating that investor sentiment is improving significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

COMPASS Pathways does not currently pay a dividend.

Dividend Growth

COMPASS Pathways does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

8.44% of the float of COMPASS Pathways has been sold short.

Short Interest Ratio / Days to Cover

COMPASS Pathways has a short interest ratio ("days to cover") of 2.6, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in COMPASS Pathways has recently decreased by 9.11%, indicating that investor sentiment is improving significantly.

News and Social Media

• Score: 3.5 / 5
• News Sentiment: 1.28

News Sentiment

COMPASS Pathways has a news sentiment score of 1.28. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.93 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 4 news articles for COMPASS Pathways this week, compared to 3 articles on an average week.

Search Interest

Only 8 people have searched for CMPS on MarketBeat in the last 30 days. This is a decrease of -56% compared to the previous 30 days.

MarketBeat Follows

6 people have added COMPASS Pathways to their MarketBeat watchlist in the last 30 days. This is an increase of 100% compared to the previous 30 days.

Company Ownership

• Score: 0.8 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, COMPASS Pathways insiders have not sold or bought any company stock.

Percentage Held by Insiders

Only 3.93% of the stock of COMPASS Pathways is held by insiders.

Percentage Held by Institutions

46.19% of the stock of COMPASS Pathways is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

CMPS Stock Analysis - Frequently Asked Questions

How have CMPS shares performed this year?

COMPASS Pathways' stock was trading at $3.78 at the beginning of 2025. Since then, CMPS shares have increased by 37.6% and is now trading at $5.20.

How were COMPASS Pathways' earnings last quarter?

COMPASS Pathways PLC Sponsored ADR (NASDAQ:CMPS) posted its quarterly earnings data on Thursday, July, 31st. The company reported ($0.38) EPS for the quarter, missing analysts' consensus estimates of ($0.37) by $0.01.
Read the conference call transcript.

When did COMPASS Pathways IPO?

COMPASS Pathways (CMPS) raised $100 million in an IPO on Friday, September 18th 2020. The company issued 6,700,000 shares at a price of $14.00-$16.00 per share. Cowen, Evercore ISI and Berenberg served as the underwriters for the IPO and Canaccord Genuity was co-manager.

Who are COMPASS Pathways' major shareholders?

COMPASS Pathways' top institutional investors include Nantahala Capital Management LLC (4.36%), ARK Investment Management LLC (1.76%), Hsbc Holdings PLC (1.12%) and 22NW LP (0.92%). Insiders that own company stock include Life Sciences NV Atai, Ekaterina Malievskaia and George Jay Goldsmith.
View institutional ownership trends.

How do I buy shares of COMPASS Pathways?

Shares of CMPS stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of COMPASS Pathways own?

Based on aggregate information from My MarketBeat watchlists, some other companies that COMPASS Pathways investors own include Symbotic (SYM), Enovix (ENVX), Rambus (RMBS), JPMorgan Nasdaq Equity Premium Income ETF (JEPQ), Ginkgo Bioworks (DNA), Toast (TOST) and Saia (SAIA).

Company Calendar

• Last Earnings: 7/31/2025
• Today: 9/14/2025
• Next Earnings (Estimated): 10/30/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: Medical Services
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:CMPS
• CIK: 1816590
• Web: www.compasspathways.com
• Phone: 716-676-6461
• Fax: N/A
• Employees: 120
• Year Founded: 2016

Price Target and Rating

• Average Price Target for COMPASS Pathways: $16.29
• High Price Target: $40.00
• Low Price Target: $6.00
• Potential Upside/Downside: +213.2%
• Consensus Rating: Moderate Buy
• Rating Score (0-4): 2.86
• Research Coverage: 7 Analysts

Profitability

• EPS (Trailing Twelve Months): ($1.84)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$155.12 million
• Net Margins: N/A
• Pretax Margin: N/A
• Return on Equity: -87.89%
• Return on Assets: -57.77%

Debt

• Debt-to-Equity Ratio: 0.16
• Current Ratio: 8.82
• Quick Ratio: 8.82

Sales & Book Value

• Annual Sales: N/A
• Price / Sales: N/A
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $2.26 per share
• Price / Book: 2.30

Miscellaneous

• Outstanding Shares: 95,941,000
• Free Float: 92,171,000
• Market Cap: $498.89 million
• Optionable: Optionable
• Beta: 2.17