eFFECTOR Therapeutics (EFTR) Short Interest Ratio & Short Volume $0.0002 0.00 (0.00%) As of 09/17/2025 10:32 AM Eastern Add Compare Share Share Short Interest Stock AnalysisChartCompetitorsInsider TradesSEC FilingsShort InterestTrendsBuy This Stock eFFECTOR Therapeutics Short Interest DataeFFECTOR Therapeutics (EFTR) has a short interest of 5,700 shares, representing 0.13% of the float (the number of shares available for trading by the public). This marks a 0.00% change in short interest from the previous month. The short interest ratio (days to cover) is 1.8, indicating that it would take 1.8 days of the average trading volume of 2,965 shares to cover all short positions.Current Short Interest5,700 sharesPrevious Short Interest5,700 sharesChange Vs. Previous MonthNo ChangeDollar Volume Sold Short$1.14Short Interest Ratio1.8 Days to CoverLast Record DateAugust 31, 2025Outstanding Shares4,704,000 sharesShort Percent of Float0.13%Today's Trading Volume283 sharesAverage Trading Volume2,965 sharesToday's Volume Vs. Average10% Short Selling eFFECTOR Therapeutics? Sign up to receive the latest short interest report for eFFECTOR Therapeutics and its competitors with MarketBeat's FREE newsletter. Email Address Get Report View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. 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Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartEFTR Short Interest Over TimeEFTR Days to Cover Over TimeEFTR Percentage of Float Shorted Over Time eFFECTOR Therapeutics Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 8/31/20255,700 shares $1.14 No Change0.1%1.8 $0.00 8/15/20255,700 shares $1.14 No ChangeN/A1.2 $0.00 7/31/20255,700 shares $1.14 No Change0.1%3.6 $0.00 7/15/20255,700 shares $1.14 No ChangeN/A4.1 $0.00 6/30/20255,700 shares $1.71 No Change0.1%5.2 $0.00 6/15/20255,700 shares $1.71 No Change0.1%0.8 $0.00 5/31/20255,700 shares $0.00 No Change0.1%0.7 $0.00 5/15/20255,700 shares $3.42 No ChangeN/A2.6 $0.00 4/30/20255,700 shares $1.14 No ChangeN/A1.1 $0.00 4/15/20255,700 shares $1.14 No ChangeN/A9.5 $0.00 Get the Latest News and Ratings for EFTR and Related StocksEnter your email address below to receive the latest news and analysts' ratings for eFFECTOR Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 3/14/20255,700 shares $3.42 No ChangeN/A3.8 $0.00 2/28/20255,700 shares $1.14 No ChangeN/A9.5 $0.00 2/14/20255,700 shares $1.14 No ChangeN/A9.5 $0.00 1/31/20255,700 shares $1.14 No ChangeN/A1.1 $0.00 1/15/20255,700 shares $1.14 No ChangeN/A2.7 $0.00 6/30/2024687,000 shares $199.30 thousand +650.0%16.8%1.1 $0.29 6/15/202491,600 shares $114.50 thousand -3.3%2.3%0.1 $1.25 5/31/202494,700 shares $151.52 thousand -14.5%2.4%0.3 $1.60 5/15/2024110,700 shares $219.19 thousand -13.7%2.9%0.3 $1.98 4/30/2024128,300 shares $288.68 thousand -47.4%3.1%0.3 $2.25 4/15/2024244,000 shares $470.92 thousand -29.3%7.2%0.7 $1.93 3/31/2024345,200 shares $4.97 million +8.5%10.7%1 $14.39 3/15/2024318,100 shares $3.52 million +43.1%15.0%2.2 $11.06 2/29/2024222,300 shares $3.21 million +113.8%10.5%1.6 $14.44 2/15/2024104,000 shares $1.21 million -4.4%4.9%0.9 $11.66 1/31/2024108,800 shares $1.25 million -12.6%5.9%1 $11.47 1/15/2024124,500 shares $1.33 million -85.0%6.7%1.3 $10.69 12/31/2023827,900 shares $386.96 thousand -21.9%1.8%0.4 $0.47 12/15/20231,060,000 shares $398.35 thousand +1.0%2.3%0.6 $0.38 11/30/20231,050,000 shares $556.92 thousand +141.9%2.3%0.8 $0.53 11/15/2023434,000 shares $253.89 thousand +72.8%1.0%0.6 $0.59 10/31/2023251,100 shares $135.59 thousand -50.5%0.7%0.6 $0.54 10/15/2023507,600 shares $291.06 thousand +133.9%1.3%1.1 $0.57 9/30/2023217,000 shares $130.18 thousand -74.0%0.6%0.5 $0.60 9/15/2023834,100 shares $508.80 thousand -8.5%2.2%1.4 $0.61 8/31/2023912,000 shares $663.94 thousand +36.7%2.4%1 $0.73 8/15/2023667,400 shares $453.23 thousand -38.8%1.7%0.3 $0.68 7/31/20231,090,000 shares $881.16 thousand -15.5%3.6%0.5 $0.81 7/15/20231,290,000 shares $990.72 thousand +219.3%4.2%0.6 $0.77 6/30/2023404,000 shares $335.40 thousand +91.4%1.4%0.2 $0.83 6/15/2023211,100 shares $197.38 thousand -83.0%0.8%0.1 $0.94 5/31/20231,240,000 shares $1.15 million +1,506.2%4.6%0.8 $0.93 5/15/202377,200 shares $52.87 thousand -12.6%0.4%0.4 $0.68 4/30/202388,300 shares $41.50 thousand -32.5%0.6%0.5 $0.47 4/15/2023130,800 shares $50.36 thousand +236.3%0.7%0.7 $0.39 3/31/202338,900 shares $13.72 thousand -45.2%0.1%0.2 $0.35 3/15/202371,000 shares $28.40 thousand +110.7%0.2%0.2 $0.40 2/28/202333,700 shares $16.79 thousand -72.2%0.3%0.1 $0.50 2/15/2023121,300 shares $72.78 thousand -9.1%0.9%0.4 $0.60 1/31/2023133,400 shares $68.45 thousand -29.3%1.0%0.4 $0.51 1/15/2023188,800 shares $84.96 thousand +56.4%1.4%0.7 $0.45 12/30/2022120,700 shares $51.61 thousand +148.9%0.9%0.5 $0.43 12/15/202248,500 shares $19.40 thousand +41.4%0.4%0.5 $0.40 11/30/202234,300 shares $14.40 thousand -49.9%0.3%0.3 $0.42 11/15/202268,400 shares $37.70 thousand -51.7%0.5%0.5 $0.55 10/31/2022141,600 shares $86.76 thousand +13.2%1.1%0.1 $0.61 10/15/2022125,100 shares $73.30 thousand -42.5%1.0%0.1 $0.59 9/30/2022217,500 shares $124.43 thousand +55.0%1.7%0.2 $0.57 9/15/2022140,300 shares $83.07 thousand -25.5%1.1%0.1 $0.59 8/31/2022188,300 shares $114.77 thousand +21.5%1.4%0.2 $0.61 8/15/2022155,000 shares $111.03 thousand +104.8%1.3%0.1 $0.72 7/31/202275,700 shares $61.30 thousand -19.5%1.0%0.1 $0.81 7/15/202294,000 shares $105.28 thousand -30.4%1.2%1.5 $1.12 6/30/2022135,000 shares $191.70 thousand -12.0%1.8%3.1 $1.42 6/15/2022153,400 shares $225.50 thousand -13.2%2.0%4 $1.47 5/31/2022176,700 shares $381.67 thousand +0.8%2.3%5.2 $2.16 5/15/2022175,300 shares $315.54 thousand -26.2%2.3%6.7 $1.80 4/30/2022237,400 shares $790.54 thousand -1.7%3.2%8.1 $3.33 4/15/2022241,600 shares $850.43 thousand -3.4%3.2%7.9 $3.52 3/31/2022250,000 shares $1.00 million -6.6%N/A7.7 $4.01 3/15/2022267,700 shares $1.07 million -11.7%3.8%4.5 $4.00 2/28/2022303,100 shares $1.41 million -6.2%4.6%3.2 $4.65 2/15/2022323,200 shares $1.49 million -2.4%N/A3 $4.61 1/31/2022331,300 shares $1.87 million -5.3%5.1%2.7 $5.65 1/15/2022350,000 shares $2.54 million -5.9%N/A2.7 $7.25 12/31/2021372,100 shares $3.08 million No Change5.0%1.9 $8.28 EFTR Short Interest - Frequently Asked Questions What is eFFECTOR Therapeutics' current short interest? Short interest is the volume of eFFECTOR Therapeutics shares that have been sold short but have not yet been closed out or covered. As of August 31st, traders have sold 5,700 shares of EFTR short. 0.13% of eFFECTOR Therapeutics' shares are currently sold short. Learn More on eFFECTOR Therapeutics' current short interest. What is a good short interest ratio for eFFECTOR Therapeutics? The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. EFTR shares currently have a short interest ratio of 2.0. Learn More on eFFECTOR Therapeutics's short interest ratio. What is a good short interest percentage for eFFECTOR Therapeutics? Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 0.13% of eFFECTOR Therapeutics' floating shares are currently sold short. How does eFFECTOR Therapeutics' short interest compare to its competitors? 0.13% of eFFECTOR Therapeutics' shares are currently sold short. Here is how the short interest of companies in the industry of "pharmaceutical products" compare to eFFECTOR Therapeutics: Smart for Life, Inc. (0.01%), Ampio Pharmaceuticals, Inc. (0.01%), PaxMedica, Inc. (0.01%), Clever Leaves Holdings Inc. (0.52%), OncoSec Medical Incorporated (0.00%), Calithera Biosciences, Inc. (0.15%), CytoMed Therapeutics Limited (0.76%), Eloxx Pharmaceuticals, Inc. (0.08%), Galapagos NV (3.27%), Indivior PLC (7.12%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: SPDR S&P 500 ETF Trust ($73.23 billion), Invesco QQQ ($29.52 billion), iShares Russell 2000 ETF ($20.82 billion), iShares 20+ Year Treasury Bond ETF ($10.76 billion), Palo Alto Networks, Inc. ($9.37 billion), Strategy Inc ($7.58 billion), Invesco S&P 500 Equal Weight ETF ($6.78 billion), SPDR S&P Biotech ETF ($6.72 billion), AppLovin Corporation ($6.37 billion), and iShares iBoxx $ Investment Grade Corporate Bond ETF ($6.29 billion). View all of the most shorted stocks. What does it mean to sell short eFFECTOR Therapeutics stock? Short selling EFTR is an investing strategy that aims to generate trading profit from eFFECTOR Therapeutics as its price is falling. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against eFFECTOR Therapeutics? A short squeeze for eFFECTOR Therapeutics occurs when it has a large amount of short interest and its stock appreciates in price. This forces short sellers to cover their short interest positions by buying actual shares of EFTR, which in turn drives the price of the stock up even further. How often is eFFECTOR Therapeutics' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including EFTR, twice per month. The most recent reporting period available is August, 31 2025. More Short Interest Resources from MarketBeat Related Companies SMFL Short Interest Data AMPE Short Interest Data PXMD Short Interest Data CLVR Short Interest Data ONCSQ Short Interest Data AIMDW Short Interest Data ALVOW Short Interest Data BFRIW Short Interest Data BCTXW Short Interest Data CALA Short Interest Data Short Interest Tools Stocks to Short Largest Short Interest Positions Short Interest Increases Short Interest Decreases Short Interest Reporting Dates This page (NASDAQ:EFTR) was last updated on 9/18/2025 by MarketBeat.com Staff From Our PartnersREVEALED: Something Big Happening Behind White House Doorswhat I just learned about what’s unfolding in the White House is truly stunning… And you need to see it for...Paradigm Press | SponsoredNvidia CEO Makes First Ever Tesla AnnouncementWhile headlines focus on Tesla’s car sales, tech analyst Jeff Brown says the real story is Tesla’s role in a $...Brownstone Research | SponsoredForget NVDA. 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