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Milestone Pharmaceuticals (MIST) Institutional Ownership

Milestone Pharmaceuticals logo
$1.16 -0.03 (-2.52%)
As of 08/28/2026 04:00 PM Eastern
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Institutional Ownership Changes (13F Filings) for Milestone Pharmaceuticals (NASDAQ:MIST)

Current
Institutional Ownership
Percentage
86.18%
Number of
Institutional Buyers
(last 12 months)
34
Total
Institutional Inflows
(last 12 months)
$29.36M
Number of
Institutional Sellers
(last 12 months)
7
Total
Institutional Outflows
(last 12 months)
$13.34M
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MIST Institutional Buying and Selling by Quarter

Milestone Pharmaceuticals Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
8/26/2026 HighTower Advisors LLC20,000$27K0.0%+100.0%0.016%
8/23/2026 Guardian Wealth Advisors LLC NC339,450$455K0.0%+21.1%0.273%
8/17/2026 Seven Fleet Capital Management LP270,233$362K0.1%-18.9%0.217%
8/14/2026 ADAR1 Capital Management LLC100,000$134K0.0%N/A0.080%
8/11/2026 TRU Independence Asset Management 2 LLC150,000$201K0.1%N/A0.120%
7/9/2026 Bay Rivers Group46,633$62K0.0%+55.9%0.037%
6/4/2026 Seven Fleet Capital Management LP333,333$397K0.1%N/A0.268%
5/14/2026 Renaissance Technologies LLC129,705$154K0.0%N/A0.108%
5/1/2026 Welch & Forbes LLC25,000$30K0.0%N/A0.021%
4/16/2026 SG Americas Securities LLC42,512$51K0.0%-56.3%0.036%
2/24/2026 TRU Independence Asset Management 2 LLC100,000$202K0.1%N/A0.117%
2/19/2026 Invesco Ltd.21,893$44K0.0%N/A0.026%
2/18/2026 XTX Topco Ltd171,960$347K0.0%-8.2%0.202%
2/18/2026 Engineers Gate Manager LP59,053$119K0.0%N/A0.069%
2/17/2026 ADAR1 Capital Management LLC100,100$202K0.0%N/A0.118%
2/17/2026 Cetera Investment Advisers20,722$42K0.0%N/A0.024%
2/17/2026 Adage Capital Partners GP L.L.C.2,810,037$5.68M0.0%-59.7%3.299%
2/17/2026 Guardian Wealth Advisors LLC NC263,200$532K0.0%+25.2%0.309%
2/17/2026 Graham Capital Management L.P.133,620$270K0.0%N/A0.157%
2/16/2026 Squarepoint Ops LLC249,344$504K0.0%N/A0.293%
2/16/2026 Aptus Capital Advisors LLC263,200$532K0.0%+25.2%0.309%
2/13/2026 Marshall Wace LLP1,656,821$3.35M0.0%+289.8%1.945%
2/11/2026 LPL Financial LLC142,463$288K0.0%+49.5%0.167%
2/11/2026 Propel Bio Management LLC4,118,321$8.32M7.1%-19.6%4.835%
2/9/2026 Eaton Financial Holdings Company LLC12,750$26K0.0%N/A0.015%
2/9/2026 Simplify Asset Management Inc.1,506,405$3.04M0.0%-46.8%1.769%
2/4/2026 Strategic Family Wealth Counselors L.L.C.12,675$25K0.0%N/A0.015%
1/20/2026 October Effect Ltd52,100$105K0.1%N/A0.061%
1/9/2026 SG Americas Securities LLC97,375$197K0.0%N/A0.114%
1/7/2026 Bay Rivers Group28,861$58K0.0%+72.9%0.034%
11/17/2025 Millennium Management LLC401,559$803K0.0%N/A0.471%
11/17/2025 Boxer Capital Management LLC666,666$1.33M0.4%N/A0.783%
11/17/2025 Bank of America Corp DE16,052$32K0.0%+200,550.0%0.019%
11/14/2025 Raymond James Financial Inc.26,600$53K0.0%-38.5%0.031%
11/14/2025 Orbimed Advisors LLC3,221,828$6.44M0.2%N/A3.791%
11/14/2025 Two Sigma Investments LP666,551$1.33M0.0%N/A0.784%
11/13/2025 Pathstone Holdings LLC1,000,000$2M0.0%N/A1.177%
11/13/2025 UBS Group AG397,534$795K0.0%+23.2%0.468%
11/12/2025 Aptus Capital Advisors LLC210,200$420K0.0%N/A0.247%
11/12/2025 Propel Bio Management LLC5,124,890$10.25M10.3%+186.1%6.030%
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11/7/2025 GSA Capital Partners LLP78,747$157K0.0%N/A0.093%
10/29/2025AMH Equity Ltd231,671$463K0.6%N/A0.273%
10/21/2025 Stephenson & Company Inc.20,000$40K0.0%N/A0.024%
10/20/2025 Simplify Asset Management Inc.2,832,974$5.67M0.1%+186.2%3.333%
10/17/2025 Sapient Capital LLC12,200$25K0.0%N/A0.014%
9/12/2025 Valeo Financial Advisors LLC130,699$254K0.0%+553.5%0.154%
8/14/2025 Raymond James Financial Inc.43,235$84K0.0%+30.1%0.081%
8/13/2025 Walleye Capital LLC15,109$29K0.0%-83.6%0.028%
8/12/2025 XTX Topco Ltd160,963$312K0.0%+209.5%0.301%
8/8/2025 Creative Planning23,410$45K0.0%+74.6%0.044%
8/7/2025 Simplify Asset Management Inc.990,000$1.92M0.1%+16.5%1.852%
7/22/2025 Valeo Financial Advisors LLC130,699$254K0.0%+553.5%0.244%
7/9/2025 Bay Rivers Group14,321$28K0.0%N/A0.027%
5/15/2025Propel Bio Management LLC1,451,557$1.16M1.3%N/A2.715%
5/14/2025Stonepine Capital Management LLC250,000$200K0.2%-50.0%0.468%
5/14/2025Walleye Capital LLC91,920$74K0.0%N/A0.172%
5/12/2025Alta Fundamental Advisers LLC1,427,479$1.14M0.7%-46.3%2.670%
5/8/2025XTX Topco Ltd52,004$42K0.0%+52.7%0.097%
2/19/2025Toronto Dominion Bank750,000$1.77M0.0%N/A1.406%
2/17/2025Stonepine Capital Management LLC500,000$1.18M1.0%-50.0%0.938%
2/17/2025Toronto Dominion Bank750,000$1.77M0.0%N/A1.406%
2/17/2025RTW Investments LP2,506,102$5.91M0.1%-23.0%4.699%
2/17/2025Millennium Management LLC2,703,259$6.38M0.0%-2.7%5.069%
2/17/2025Lion Point Capital LP1,025,806$2.42M12.7%-38.0%1.924%
2/17/2025Cubist Systematic Strategies LLC30,938$73K0.0%N/A0.058%
2/14/2025Boxer Capital Management LLC309,007$729K0.1%N/A0.579%
2/14/2025Nantahala Capital Management LLC1,445,264$3.41M0.1%-17.4%2.710%
2/14/2025Northern Trust Corp58,108$137K0.0%+112.6%0.109%
2/14/2025Two Sigma Securities LLC16,957$40K0.0%-26.7%0.032%
2/13/2025XTX Topco Ltd34,054$80K0.0%N/A0.064%
2/13/2025Envestnet Asset Management Inc.63,742$150K0.0%-9.7%0.120%
2/12/2025National Bank of Canada FI18,700$44K0.0%+163.4%0.035%
2/11/2025Virtu Financial LLC71,955$170K0.0%N/A0.135%
2/6/2025Jones Financial Companies Lllp11,000$26K0.0%+1,000.0%0.021%
1/24/2025Clear Creek Financial Management LLC10,500$25K0.0%-46.2%0.020%
11/25/2024PVG Asset Management Corp30,345$46K0.2%N/A0.057%
11/14/2024Stonepine Capital Management LLC999,790$1.52M1.0%-19.3%1.877%
11/5/2024BML Capital Management LLC1,136,091$1.73M1.0%+3.0%2.133%
11/1/2024Atria Investments Inc40,421$61K0.0%+44.4%0.076%
10/10/2024Valeo Financial Advisors LLC20,000$30K0.0%+100.0%0.038%
8/21/2024Stonepine Capital Management LLC1,239,199$1.64M1.5%-15.3%2.327%
8/15/2024Lion Point Capital LP2,340,207$3.09M5.6%+1.7%4.394%
8/15/2024Millennium Management LLC2,749,930$3.66M0.0%-3.7%5.163%
5/1/2024BNP Paribas Financial Markets16,900$30K0.0%+177.0%0.032%
4/26/2024Clear Creek Financial Management LLC25,000$45K0.0%-21.3%0.047%
4/23/2024BML Capital Management LLC606,145$1.09M0.7%+37.0%1.140%
1/30/2024BML Capital Management LLC442,352$739K0.6%+62.3%1.321%
9/21/2023Barclays PLC800,776$2.28M0.0%-5.4%2.399%
8/21/2023Affinity Asset Advisors LLC300,068$855K0.3%+50.5%0.899%
8/11/2023Beta Wealth Group Inc.14,127$40K0.0%N/A0.042%
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8/3/2023Barclays PLC800,776$2.28M0.0%-5.4%2.400%
7/27/2023Virtu Financial LLC11,743$33K0.0%N/A0.035%
7/24/2023BML Capital Management LLC272,500$777K0.7%+23.9%0.817%
7/17/2023Clear Creek Financial Management LLC31,929$91K0.0%-11.1%0.096%
7/14/2023Valeo Financial Advisors LLC118,699$338K0.0%+4.4%0.356%
5/16/2023Alta Fundamental Advisers LLC897,961$3.54M1.5%+58.8%2.698%
5/15/2023Affinity Asset Advisors LLC199,382$786K0.3%+99.4%0.599%
5/15/2023RTW Investments LP3,256,102$12.83M0.3%-24.5%9.782%
5/4/2023Barclays PLC846,828$3.34M0.0%+32.0%2.544%
4/20/2023Clear Creek Financial Management LLC35,929$142K0.0%N/A0.108%


MIST Institutional Ownership - Frequently Asked Questions

During the previous two years, 56 institutional investors and hedge funds held shares of Milestone Pharmaceuticals. The most heavily invested institutionals were Propel Bio Management LLC ($8.32M), Orbimed Advisors LLC ($6.44M), RTW Investments LP ($5.91M), Adage Capital Partners GP L.L.C. ($5.68M), Nantahala Capital Management LLC ($3.41M), Marshall Wace LLP ($3.35M), and Simplify Asset Management Inc. ($3.04M).Learn more on Milestone Pharmaceuticals' institutional investors.

86.18% of Milestone Pharmaceuticals' stock is owned by institutional investors. Learn more on MIST's institutional investor holdings.

Of the 47 institutional investors that purchased Milestone Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Propel Bio Management LLC ($4.78M), Orbimed Advisors LLC ($3.22M), Simplify Asset Management Inc. ($1.98M), Toronto Dominion Bank ($1.50M), Marshall Wace LLP ($1.23M), Pathstone Holdings LLC ($1M), and Boxer Capital Management LLC ($975.67K).

Institutional investors have bought a total of 14,968,076 shares in the last 24 months. This purchase volume represents approximately $29.36M in transactions.

The following institutional investors have sold Milestone Pharmaceuticals stock in the last 24 months: Adage Capital Partners GP L.L.C. ($4.17M), Simplify Asset Management Inc. ($1.33M), Propel Bio Management LLC ($1.01M), Seven Fleet Capital Management LP ($63.10K), SG Americas Securities LLC ($54.86K), Raymond James Financial Inc. ($16.64K), and XTX Topco Ltd ($15.34K).

Institutional investors have sold a total of 6,649,040 shares in the last 24 months. This volume of shares sold represents approximately $13.34M in transactions.


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Institutional ownership data for NASDAQ:MIST is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 8/26/2026. New 13F filings are added each quarter as they're published.
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