Is MIST or CADL more profitable?

Candel Therapeutics' return on equity of -60.42% beat Milestone Pharmaceuticals' return on equity. Company Net Margins Return on Equity Return on Assets Milestone Pharmaceuticals N/A -339.33% -61.79% Candel Therapeutics N/A -60.42% -41.33%

Milestone Pharmaceuticals (MIST) Competitors

$1.33 +0.09 (+7.26%)

Closing price 04:00 PM Eastern

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$1.34 +0.01 (+0.75%)

As of 04:30 PM Eastern

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MIST vs. ACRS, CADL, GYRE, DNA, and AQST

Should you buy Milestone Pharmaceuticals stock or one of its competitors? MarketBeat compares Milestone Pharmaceuticals with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Milestone Pharmaceuticals include Aclaris Therapeutics (ACRS), Candel Therapeutics (CADL), Gyre Therapeutics (GYRE), Ginkgo Bioworks (DNA), and Aquestive Therapeutics (AQST). These companies are all part of the "pharmaceutical products" industry.

How does Milestone Pharmaceuticals compare to Aclaris Therapeutics?

Aclaris Therapeutics (NASDAQ:ACRS) and Milestone Pharmaceuticals (NASDAQ:MIST) are both small-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their valuation, profitability, earnings, media sentiment, risk, analyst recommendations, institutional ownership and dividends.

Aclaris Therapeutics currently has a consensus price target of $11.50, suggesting a potential upside of 129.08%. Milestone Pharmaceuticals has a consensus price target of $7.25, suggesting a potential upside of 445.11%. Given Milestone Pharmaceuticals' higher possible upside, analysts clearly believe Milestone Pharmaceuticals is more favorable than Aclaris Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Aclaris Therapeutics	1 Sell rating(s)	0 Hold rating(s)	4 Buy rating(s)	3 Strong Buy rating(s)	3.13
Milestone Pharmaceuticals	2 Sell rating(s)	0 Hold rating(s)	3 Buy rating(s)	1 Strong Buy rating(s)	2.50

Aclaris Therapeutics has a beta of 0.76, meaning that its stock price is 24% less volatile than the broader market. Comparatively, Milestone Pharmaceuticals has a beta of 0.96, meaning that its stock price is 4% less volatile than the broader market.

Milestone Pharmaceuticals has lower revenue, but higher earnings than Aclaris Therapeutics. Aclaris Therapeutics is trading at a lower price-to-earnings ratio than Milestone Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Aclaris Therapeutics	$8.37M	83.80	-$64.92M	-$0.56	N/A
Milestone Pharmaceuticals	$1.55M	106.83	-$63.06M	-$0.68	N/A

Milestone Pharmaceuticals has a net margin of 0.00% compared to Aclaris Therapeutics' net margin of -832.58%. Aclaris Therapeutics' return on equity of -55.89% beat Milestone Pharmaceuticals' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Aclaris Therapeutics	-832.58%	-55.89%	-38.49%
Milestone Pharmaceuticals	N/A	-339.33%	-61.79%

In the previous week, Aclaris Therapeutics had 1 more articles in the media than Milestone Pharmaceuticals. MarketBeat recorded 2 mentions for Aclaris Therapeutics and 1 mentions for Milestone Pharmaceuticals. Milestone Pharmaceuticals' average media sentiment score of 1.89 beat Aclaris Therapeutics' score of 0.62 indicating that Milestone Pharmaceuticals is being referred to more favorably in the news media.

Company	Overall Sentiment
Aclaris Therapeutics	Positive
Milestone Pharmaceuticals	Very Positive

98.3% of Aclaris Therapeutics shares are held by institutional investors. Comparatively, 86.2% of Milestone Pharmaceuticals shares are held by institutional investors. 4.8% of Aclaris Therapeutics shares are held by insiders. Comparatively, 5.0% of Milestone Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

Summary

Aclaris Therapeutics beats Milestone Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Milestone Pharmaceuticals compare to Candel Therapeutics?

Milestone Pharmaceuticals (NASDAQ:MIST) and Candel Therapeutics (NASDAQ:CADL) are both small-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their risk, analyst recommendations, dividends, institutional ownership, earnings, media sentiment, valuation and profitability.

Milestone Pharmaceuticals presently has a consensus target price of $7.25, indicating a potential upside of 445.11%. Candel Therapeutics has a consensus target price of $18.00, indicating a potential upside of 73.75%. Given Milestone Pharmaceuticals' higher probable upside, analysts clearly believe Milestone Pharmaceuticals is more favorable than Candel Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Milestone Pharmaceuticals	2 Sell rating(s)	0 Hold rating(s)	3 Buy rating(s)	1 Strong Buy rating(s)	2.50
Candel Therapeutics	1 Sell rating(s)	2 Hold rating(s)	6 Buy rating(s)	0 Strong Buy rating(s)	2.56

Candel Therapeutics' return on equity of -60.42% beat Milestone Pharmaceuticals' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Milestone Pharmaceuticals	N/A	-339.33%	-61.79%
Candel Therapeutics	N/A	-60.42%	-41.33%

In the previous week, Candel Therapeutics had 4 more articles in the media than Milestone Pharmaceuticals. MarketBeat recorded 5 mentions for Candel Therapeutics and 1 mentions for Milestone Pharmaceuticals. Milestone Pharmaceuticals' average media sentiment score of 1.89 beat Candel Therapeutics' score of 0.31 indicating that Milestone Pharmaceuticals is being referred to more favorably in the media.

Company	Overall Sentiment
Milestone Pharmaceuticals	Very Positive
Candel Therapeutics	Neutral

86.2% of Milestone Pharmaceuticals shares are held by institutional investors. Comparatively, 13.9% of Candel Therapeutics shares are held by institutional investors. 5.0% of Milestone Pharmaceuticals shares are held by insiders. Comparatively, 14.3% of Candel Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

Candel Therapeutics has lower revenue, but higher earnings than Milestone Pharmaceuticals. Candel Therapeutics is trading at a lower price-to-earnings ratio than Milestone Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Milestone Pharmaceuticals	$1.55M	106.83	-$63.06M	-$0.68	N/A
Candel Therapeutics	N/A	N/A	-$38.18M	-$0.98	N/A

Milestone Pharmaceuticals has a beta of 0.96, indicating that its share price is 4% less volatile than the broader market. Comparatively, Candel Therapeutics has a beta of -0.49, indicating that its share price is 149% less volatile than the broader market.

Summary

Milestone Pharmaceuticals beats Candel Therapeutics on 8 of the 15 factors compared between the two stocks.

How does Milestone Pharmaceuticals compare to Gyre Therapeutics?

Milestone Pharmaceuticals (NASDAQ:MIST) and Gyre Therapeutics (NASDAQ:GYRE) are both small-cap medical companies, but which is the superior business? We will contrast the two companies based on the strength of their analyst recommendations, valuation, earnings, profitability, media sentiment, institutional ownership, risk and dividends.

Milestone Pharmaceuticals has a net margin of 0.00% compared to Gyre Therapeutics' net margin of -5.44%. Gyre Therapeutics' return on equity of 3.13% beat Milestone Pharmaceuticals' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Milestone Pharmaceuticals	N/A	-339.33%	-61.79%
Gyre Therapeutics	-5.44%	3.13%	2.67%

In the previous week, Milestone Pharmaceuticals and Milestone Pharmaceuticals both had 1 articles in the media. Milestone Pharmaceuticals' average media sentiment score of 1.89 beat Gyre Therapeutics' score of 1.87 indicating that Milestone Pharmaceuticals is being referred to more favorably in the media.

Company	Overall Sentiment
Milestone Pharmaceuticals	Very Positive
Gyre Therapeutics	Very Positive

Milestone Pharmaceuticals currently has a consensus target price of $7.25, indicating a potential upside of 445.11%. Gyre Therapeutics has a consensus target price of $17.00, indicating a potential upside of 163.57%. Given Milestone Pharmaceuticals' stronger consensus rating and higher probable upside, equities analysts plainly believe Milestone Pharmaceuticals is more favorable than Gyre Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Milestone Pharmaceuticals	2 Sell rating(s)	0 Hold rating(s)	3 Buy rating(s)	1 Strong Buy rating(s)	2.50
Gyre Therapeutics	2 Sell rating(s)	0 Hold rating(s)	2 Buy rating(s)	0 Strong Buy rating(s)	2.00

Milestone Pharmaceuticals has a beta of 0.96, suggesting that its share price is 4% less volatile than the broader market. Comparatively, Gyre Therapeutics has a beta of 1.91, suggesting that its share price is 91% more volatile than the broader market.

Gyre Therapeutics has higher revenue and earnings than Milestone Pharmaceuticals. Gyre Therapeutics is trading at a lower price-to-earnings ratio than Milestone Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Milestone Pharmaceuticals	$1.55M	106.83	-$63.06M	-$0.68	N/A
Gyre Therapeutics	$117.05M	6.14	$5.03M	-$0.09	N/A

86.2% of Milestone Pharmaceuticals shares are held by institutional investors. Comparatively, 24.0% of Gyre Therapeutics shares are held by institutional investors. 5.0% of Milestone Pharmaceuticals shares are held by insiders. Comparatively, 9.5% of Gyre Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Summary

Milestone Pharmaceuticals beats Gyre Therapeutics on 9 of the 16 factors compared between the two stocks.

How does Milestone Pharmaceuticals compare to Ginkgo Bioworks?

Milestone Pharmaceuticals (NASDAQ:MIST) and Ginkgo Bioworks (NYSE:DNA) are both small-cap medical companies, but which is the superior stock? We will compare the two companies based on the strength of their media sentiment, analyst recommendations, profitability, earnings, dividends, valuation, risk and institutional ownership.

86.2% of Milestone Pharmaceuticals shares are held by institutional investors. Comparatively, 78.6% of Ginkgo Bioworks shares are held by institutional investors. 5.0% of Milestone Pharmaceuticals shares are held by company insiders. Comparatively, 12.7% of Ginkgo Bioworks shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

In the previous week, Milestone Pharmaceuticals and Milestone Pharmaceuticals both had 1 articles in the media. Milestone Pharmaceuticals' average media sentiment score of 1.89 beat Ginkgo Bioworks' score of 0.00 indicating that Milestone Pharmaceuticals is being referred to more favorably in the media.

Company	Overall Sentiment
Milestone Pharmaceuticals	Very Positive
Ginkgo Bioworks	Neutral

Milestone Pharmaceuticals has a net margin of 0.00% compared to Ginkgo Bioworks' net margin of -215.41%. Ginkgo Bioworks' return on equity of -56.08% beat Milestone Pharmaceuticals' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Milestone Pharmaceuticals	N/A	-339.33%	-61.79%
Ginkgo Bioworks	-215.41%	-56.08%	-26.06%

Milestone Pharmaceuticals presently has a consensus price target of $7.25, indicating a potential upside of 445.11%. Ginkgo Bioworks has a consensus price target of $8.50, indicating a potential downside of 16.93%. Given Milestone Pharmaceuticals' stronger consensus rating and higher probable upside, equities research analysts clearly believe Milestone Pharmaceuticals is more favorable than Ginkgo Bioworks.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Milestone Pharmaceuticals	2 Sell rating(s)	0 Hold rating(s)	3 Buy rating(s)	1 Strong Buy rating(s)	2.50
Ginkgo Bioworks	2 Sell rating(s)	0 Hold rating(s)	1 Buy rating(s)	0 Strong Buy rating(s)	1.67

Milestone Pharmaceuticals has a beta of 0.96, suggesting that its share price is 4% less volatile than the broader market. Comparatively, Ginkgo Bioworks has a beta of 1.79, suggesting that its share price is 79% more volatile than the broader market.

Milestone Pharmaceuticals has higher earnings, but lower revenue than Ginkgo Bioworks. Milestone Pharmaceuticals is trading at a lower price-to-earnings ratio than Ginkgo Bioworks, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Milestone Pharmaceuticals	$1.55M	106.83	-$63.06M	-$0.68	N/A
Ginkgo Bioworks	$170.15M	3.93	-$312.76M	-$5.36	N/A

Summary

Milestone Pharmaceuticals beats Ginkgo Bioworks on 10 of the 16 factors compared between the two stocks.

How does Milestone Pharmaceuticals compare to Aquestive Therapeutics?

Aquestive Therapeutics (NASDAQ:AQST) and Milestone Pharmaceuticals (NASDAQ:MIST) are both small-cap medical companies, but which is the better business? We will contrast the two companies based on the strength of their dividends, valuation, analyst recommendations, media sentiment, institutional ownership, risk, profitability and earnings.

In the previous week, Aquestive Therapeutics had 5 more articles in the media than Milestone Pharmaceuticals. MarketBeat recorded 6 mentions for Aquestive Therapeutics and 1 mentions for Milestone Pharmaceuticals. Milestone Pharmaceuticals' average media sentiment score of 1.89 beat Aquestive Therapeutics' score of 0.39 indicating that Milestone Pharmaceuticals is being referred to more favorably in the news media.

Company	Overall Sentiment
Aquestive Therapeutics	Neutral
Milestone Pharmaceuticals	Very Positive

Milestone Pharmaceuticals has a net margin of 0.00% compared to Aquestive Therapeutics' net margin of -137.08%. Aquestive Therapeutics' return on equity of 0.00% beat Milestone Pharmaceuticals' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Aquestive Therapeutics	-137.08%	N/A	-49.33%
Milestone Pharmaceuticals	N/A	-339.33%	-61.79%

Milestone Pharmaceuticals has lower revenue, but higher earnings than Aquestive Therapeutics. Aquestive Therapeutics is trading at a lower price-to-earnings ratio than Milestone Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Aquestive Therapeutics	$50.27M	10.38	-$83.78M	-$0.61	N/A
Milestone Pharmaceuticals	$1.55M	106.83	-$63.06M	-$0.68	N/A

32.5% of Aquestive Therapeutics shares are owned by institutional investors. Comparatively, 86.2% of Milestone Pharmaceuticals shares are owned by institutional investors. 6.8% of Aquestive Therapeutics shares are owned by insiders. Comparatively, 5.0% of Milestone Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Aquestive Therapeutics currently has a consensus price target of $8.50, indicating a potential upside of 104.33%. Milestone Pharmaceuticals has a consensus price target of $7.25, indicating a potential upside of 445.11%. Given Milestone Pharmaceuticals' higher probable upside, analysts clearly believe Milestone Pharmaceuticals is more favorable than Aquestive Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Aquestive Therapeutics	1 Sell rating(s)	0 Hold rating(s)	4 Buy rating(s)	2 Strong Buy rating(s)	3.00
Milestone Pharmaceuticals	2 Sell rating(s)	0 Hold rating(s)	3 Buy rating(s)	1 Strong Buy rating(s)	2.50

Aquestive Therapeutics has a beta of 1.46, indicating that its stock price is 46% more volatile than the broader market. Comparatively, Milestone Pharmaceuticals has a beta of 0.96, indicating that its stock price is 4% less volatile than the broader market.

Summary

Aquestive Therapeutics beats Milestone Pharmaceuticals on 10 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding MIST and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.

MIST vs. The Competition

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Metric	Milestone Pharmaceuticals	MED Industry	Medical Sector	NASDAQ Exchange
Market Cap	$165.59M	$3.66B	$6.85B	$12.43B
Dividend Yield	N/A	2.22%	2.67%	6.11%
P/E Ratio	-1.96	21.26	25.82	24.36
Price / Sales	106.83	344.09	549.91	101.32
Price / Cash	N/A	62.10	29.09	36.93
Price / Book	3.41	8.71	10.97	6.50
Net Income	-$63.06M	$23.92M	$3.58B	$336.61M
7 Day Performance	1.53%	4.16%	3.00%	0.89%
1 Month Performance	-6.34%	1.64%	0.67%	-0.36%
1 Year Performance	-28.49%	69.77%	36.72%	31.12%

Milestone Pharmaceuticals Competitors List

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Company	MarketRank	Share Price	Analysts' Price Target	1Y Price Performance	Market Cap	Revenue	P/E Ratio	Employee Count	Indicator(s)
MIST Milestone Pharmaceuticals	2.4408 of 5 stars	$1.33 +7.3%	$7.25 +445.1%	-33.3%	$165.59M	$1.55M	N/A	30
ACRS Aclaris Therapeutics	3.1047 of 5 stars	$4.84 +7.6%	$11.50 +137.6%	+240.1%	$628.49M	$8.37M	N/A	100
CADL Candel Therapeutics	2.786 of 5 stars	$9.15 +10.1%	$18.00 +96.7%	+99.8%	$608.88M	N/A	N/A	60
GYRE Gyre Therapeutics	2.1642 of 5 stars	$6.13 -1.9%	$17.00 +177.3%	-14.7%	$606.43M	$117.05M	N/A	40
DNA Ginkgo Bioworks	0.2877 of 5 stars	$9.02 -1.7%	$8.50 -5.7%	+8.3%	$599.03M	$170.15M	N/A	640	Analyst Upgrade

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This page (NASDAQ:MIST) was last updated on 6/29/2026 by MarketBeat.com Staff.

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Milestone Pharmaceuticals (MIST) Competitors

MIST vs. ACRS, CADL, GYRE, DNA, and AQST

How does Milestone Pharmaceuticals compare to Aclaris Therapeutics?

Summary

How does Milestone Pharmaceuticals compare to Candel Therapeutics?

Summary

How does Milestone Pharmaceuticals compare to Gyre Therapeutics?

Summary

How does Milestone Pharmaceuticals compare to Ginkgo Bioworks?

Summary

How does Milestone Pharmaceuticals compare to Aquestive Therapeutics?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

MIST vs. The Competition

Milestone Pharmaceuticals Competitors List

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Stock Ideas and Recommendations

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Milestone Pharmaceuticals (MIST) Competitors

MIST vs. ACRS, CADL, GYRE, DNA, and AQST

How does Milestone Pharmaceuticals compare to Aclaris Therapeutics?

Do analysts prefer ACRS or MIST?

Which has more risk and volatility, ACRS or MIST?

Which has better valuation and earnings, ACRS or MIST?

Is ACRS or MIST more profitable?

Does the media prefer ACRS or MIST?

Do institutionals & insiders hold more shares of ACRS or MIST?

Summary

How does Milestone Pharmaceuticals compare to Candel Therapeutics?

Do analysts rate MIST or CADL?

Is MIST or CADL more profitable?

Does the media refer more to MIST or CADL?

Do insiders & institutionals believe in MIST or CADL?

Which has better valuation and earnings, MIST or CADL?

Which has more volatility & risk, MIST or CADL?

Summary

How does Milestone Pharmaceuticals compare to Gyre Therapeutics?

Is MIST or GYRE more profitable?

Does the media refer more to MIST or GYRE?

Do analysts prefer MIST or GYRE?

Which has more risk and volatility, MIST or GYRE?

Which has higher valuation and earnings, MIST or GYRE?

Do institutionals & insiders believe in MIST or GYRE?

Summary

How does Milestone Pharmaceuticals compare to Ginkgo Bioworks?

Do institutionals and insiders believe in MIST or DNA?

Does the media refer more to MIST or DNA?

Is MIST or DNA more profitable?

Do analysts prefer MIST or DNA?

Which has more volatility and risk, MIST or DNA?

Which has preferable earnings & valuation, MIST or DNA?

Summary

How does Milestone Pharmaceuticals compare to Aquestive Therapeutics?

Does the media favor AQST or MIST?

Is AQST or MIST more profitable?

Which has higher valuation & earnings, AQST or MIST?

Do insiders & institutionals believe in AQST or MIST?

Do analysts recommend AQST or MIST?

Which has more risk & volatility, AQST or MIST?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

MIST vs. The Competition

Milestone Pharmaceuticals Competitors List

Related Companies and Tools

MarketBeat All Access Features

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools