| 2/14/2020 | Bank of America Corp DE | 134,649 | $0.52M | 0.0% | -6.9% | 0.438% | |
| 2/14/2020 | Jacobs Levy Equity Management Inc. | 68,641 | $0.26M | 0.0% | -16.8% | 0.223% | |
| 2/14/2020 | Sofinnova Investments Inc. | 1,515,629 | $5.80M | 0.4% | +5.4% | 4.929% | |
| 2/13/2020 | Mercer Global Advisors Inc. ADV | 137,746 | $0.53M | 0.0% | +222.2% | 0.448% | |
| 2/13/2020 | Renaissance Technologies LLC | 1,939,965 | $7.43M | 0.0% | +12.7% | 6.309% | |
| 1/31/2020 | Ikarian Capital LLC | 1,067,271 | $4.09M | 0.7% | N/A | 3.471% | |
| 11/27/2019 | Man Group plc | 111,140 | $0.27M | 0.0% | -26.2% | 0.361% | |
| 8/16/2019 | First Manhattan Co. | 2,938,633 | $8.08M | 0.0% | -1.4% | 9.557% | |
| 8/14/2019 | D. E. Shaw & Co. Inc. | 830,754 | $2.29M | 0.0% | -1.2% | 2.702% | |
| 8/14/2019 | Morgan Stanley | 21,355 | $58K | 0.0% | -17.7% | 0.069% | |
| 8/14/2019 | Man Group plc | 150,640 | $0.41M | 0.0% | +4.5% | 0.490% | |
| 8/14/2019 | Vanguard Group Inc. | 1,176,798 | $3.24M | 0.0% | +0.5% | 3.827% | |
| 8/13/2019 | Jacobs Levy Equity Management Inc. | 90,798 | $0.25M | 0.0% | -14.6% | 0.295% | |
| 8/13/2019 | Eversept Partners LP | 194,429 | $0.54M | 0.2% | +8.0% | 0.632% | |
| 8/13/2019 | BlackRock Inc. | 844,466 | $2.32M | 0.0% | +1.0% | 2.746% | |
| 8/13/2019 | Parametric Portfolio Associates LLC | 12,627 | $35K | 0.0% | -48.2% | 0.041% | |
| 8/13/2019 | Sofinnova Investments Inc. | 1,337,568 | $3.68M | 0.3% | +30.6% | 4.350% | |
| 8/12/2019 | Renaissance Technologies LLC | 1,722,917 | $4.74M | 0.0% | +5.2% | 5.603% | |
| 8/8/2019 | Acadian Asset Management LLC | 125,088 | $0.35M | 0.0% | +5.1% | 0.407% | |
| 8/7/2019 | Connor Clark & Lunn Investment Management Ltd. | 14,400 | $40K | 0.0% | -43.3% | 0.047% | |
| 8/7/2019 | JPMorgan Chase & Co. | 111,097 | $0.28M | 0.0% | -42.1% | 0.361% | |
| 5/9/2019 | Acadian Asset Management LLC | 119,044 | $0.31M | 0.0% | +31.6% | 0.388% | |
| 5/8/2019 | Connor Clark & Lunn Investment Management Ltd. | 25,400 | $67K | 0.0% | -26.6% | 0.083% | |
| 5/7/2019 | Spark Investment Management LLC | 46,207 | $0.12M | 0.0% | +59.5% | 0.151% | |
| 4/23/2019 | Mercer Global Advisors Inc. ADV | 85,701 | $0.23M | 0.0% | N/A | 0.279% | |
| 4/12/2019 | First Manhattan Co. | 2,981,633 | $7.84M | 0.0% | -2.0% | 9.717% | |
| 4/1/2019 | Deutsche Bank AG | 31,050 | $57K | 0.0% | -66.5% | 0.101% | |
| 2/22/2019 | Sofinnova Investments Inc. | 1,023,865 | $1.89M | 0.2% | +3.7% | 3.343% | |
| 2/15/2019 | 683 Capital Management LLC | 1,100,000 | $2.04M | 0.1% | +37.5% | 3.591% | |
| 2/15/2019 | Millennium Management LLC | 90,794 | $0.17M | 0.0% | -78.1% | 0.296% | |
| 2/14/2019 | D. E. Shaw & Co. Inc. | 859,838 | $1.59M | 0.0% | -4.3% | 2.807% | |
| 2/14/2019 | Bank of America Corp DE | 87,702 | $0.16M | 0.0% | -8.1% | 0.286% | |
| 2/14/2019 | Barclays PLC | 22,317 | $41K | 0.0% | -78.5% | 0.073% | |
| 2/14/2019 | Pura Vida Investments LLC | 896,387 | $1.66M | 1.0% | +211.6% | 2.927% | |
| 2/12/2019 | Connor Clark & Lunn Investment Management Ltd. | 34,600 | $64K | 0.0% | -27.0% | 0.113% | |
| 2/11/2019 | Bank of New York Mellon Corp | 44,164 | $82K | 0.0% | -91.1% | 0.144% | |
| 2/8/2019 | BlackRock Inc. | 841,216 | $1.56M | 0.0% | +4.4% | 2.746% | |
| 2/7/2019 | Acadian Asset Management LLC | 90,493 | $0.17M | 0.0% | +14.9% | 0.295% | |
| 1/30/2019 | First Manhattan Co. | 3,041,794 | $5.63M | 0.0% | +71.7% | 9.931% | |
| 12/13/2018 | Vanguard Group Inc | 1,127,033 | $3.10M | 0.0% | +11.2% | 3.680% | |
| 11/23/2018 | Vanguard Group Inc. | 1,127,033 | $3.10M | 0.0% | +11.2% | 3.680% | |
| 11/15/2018 | Man Group plc | 346,763 | $0.95M | 0.0% | -17.7% | 1.132% | |
| 11/13/2018 | Renaissance Technologies LLC | 1,439,700 | $3.96M | 0.0% | +6.3% | 4.700% | |
| 11/13/2018 | Dimensional Fund Advisors LP | 1,486,012 | $4.09M | 0.0% | +5.7% | 4.851% | |
| 11/7/2018 | JPMorgan Chase & Co. | 189,033 | $0.52M | 0.0% | -23.9% | 0.617% | |
| 10/15/2018 | First Manhattan Co. | 1,771,873 | $4.87M | 0.0% | -6.8% | 5.785% | |
| 9/18/2018 | Northern Trust Corp | 92,419 | $0.36M | 0.0% | -71.0% | 0.302% | |
| 9/17/2018 | 683 Capital Management LLC | 800,000 | $3.08M | 0.2% | +23.1% | 2.612% | |
| 8/15/2018 | Jane Street Group LLC | 28,271 | $0.11M | 0.0% | N/A | 0.092% | |
| 8/15/2018 | Millennium Management LLC | 596,329 | $2.30M | 0.0% | +409.4% | 1.947% | |
| 8/14/2018 | Paloma Partners Management Co | 137,299 | $0.53M | 0.0% | N/A | 0.448% | |
| 8/13/2018 | Laurion Capital Management LP | 32,600 | $0.13M | 0.0% | N/A | 0.106% | |
| 8/13/2018 | Renaissance Technologies LLC | 1,354,800 | $5.22M | 0.0% | +33.3% | 4.423% | |
| 8/11/2018 | Citadel Advisors LLC | 63,155 | $0.24M | 0.0% | -37.3% | 0.207% | |
| 8/10/2018 | Dimensional Fund Advisors LP | 1,406,221 | $5.41M | 0.0% | +25.1% | 4.598% | |
| 8/9/2018 | BlackRock Inc. | 805,448 | $3.10M | 0.0% | -61.1% | 2.634% | |
| 8/8/2018 | Schwab Charles Investment Management Inc. | 81,750 | $0.32M | 0.0% | -28.7% | 0.267% | |
| 8/6/2018 | Bank of New York Mellon Corp | 496,935 | $1.91M | 0.0% | -17.7% | 1.625% | |
| 8/3/2018 | LMR Partners LLP | 97,048 | $0.37M | 0.0% | N/A | 0.317% | |
| 7/24/2018 | Acadian Asset Management LLC | 78,757 | $0.30M | 0.0% | +61.7% | 0.258% | |
| 5/16/2018 | Millennium Management LLC | 117,058 | $0.49M | 0.0% | -66.2% | 0.383% | |
| 5/15/2018 | Sofinnova Ventures Inc | 98,624 | $0.41M | 0.1% | N/A | 0.323% | |
| 5/15/2018 | A.R.T. Advisors LLC | 65,526 | $0.28M | 0.0% | -48.3% | 0.214% | |
| 5/11/2018 | Dimensional Fund Advisors LP | 1,124,019 | $4.72M | 0.0% | +28.1% | 3.676% | |
| 5/10/2018 | JPMorgan Chase & Co. | 265,771 | $1.12M | 0.0% | +4,257.6% | 0.869% | |
| 5/9/2018 | BlackRock Inc. | 2,070,337 | $8.70M | 0.0% | +0.9% | 6.770% | |
| 5/3/2018 | Trexquant Investment LP | 31,153 | $0.13M | 0.0% | N/A | 0.102% | |
| 2/22/2018 | Elkfork Partners LLC | 27,188 | $0.15M | 0.0% | N/A | 0.090% | |
| 2/16/2018 | J. Goldman & Co LP | 273,000 | $1.52M | 0.1% | N/A | 0.900% | |
| 2/15/2018 | 683 Capital Management LLC | 550,000 | $3.05M | 0.3% | N/A | 1.813% | |
| 2/15/2018 | Crestline Management LP | 264,648 | $1.47M | 0.2% | N/A | 0.872% | |
| 2/15/2018 | Millennium Management LLC | 346,468 | $1.92M | 0.0% | -61.9% | 1.142% | |
| 2/15/2018 | Flinton Capital Management LLC | 33,014 | $0.18M | 0.0% | -21.7% | 0.109% | |
| 2/14/2018 | Nexthera Capital LP | 602,748 | $3.35M | 0.6% | N/A | 1.987% | |
| 2/14/2018 | TIAA CREF Investment Management LLC | 250,542 | $1.39M | 0.0% | +238.5% | 0.826% | |
| 2/14/2018 | Two Sigma Advisers LP | 80,900 | $0.45M | 0.0% | -41.0% | 0.267% | |
| 2/14/2018 | Goldman Sachs Group Inc. | 109,521 | $0.61M | 0.0% | -22.0% | 0.361% | |
| 2/14/2018 | Deutsche Bank AG | 351,180 | $1.95M | 0.0% | +625.3% | 1.157% | |
| 2/14/2018 | Highland Capital Management LP | 40,000 | $0.22M | 0.0% | N/A | 0.132% | |
| 2/13/2018 | Renaissance Technologies LLC | 737,650 | $4.09M | 0.0% | N/A | 2.431% | |
| 2/13/2018 | Bogle Investment Management L P DE | 362,086 | $2.01M | 0.1% | N/A | 1.193% | |
| 2/13/2018 | Geode Capital Management LLC | 208,652 | $1.16M | 0.0% | -5.2% | 0.688% | |
| 2/12/2018 | DLD Asset Management LP | 510,000 | $2.83M | 0.2% | +110.2% | 1.681% | |
| 2/12/2018 | Hudson Bay Capital Management LP | 200,000 | $1.11M | 0.0% | +33.3% | 0.659% | |
| 2/9/2018 | Virtu Financial LLC | 24,772 | $0.14M | 0.0% | -75.6% | 0.082% | |
| 2/9/2018 | BlackRock Inc. | 2,051,616 | $11.39M | 0.0% | -18.4% | 6.762% | |
| 2/9/2018 | Bank of New York Mellon Corp | 635,160 | $3.52M | 0.0% | +6.4% | 2.093% | |
| 2/8/2018 | The Manufacturers Life Insurance Company | 22,377 | $0.13M | 0.0% | +2,178.7% | 0.074% | |
| 2/1/2018 | Worth Venture Partners LLC | 53,760 | $0.30M | 0.4% | +67.6% | 0.177% | |
| 1/29/2018 | Lakeview Capital Partners LLC | 26,000 | $0.14M | 0.1% | -29.7% | 0.086% | |
| 1/22/2018 | First Manhattan Co. | 1,902,000 | $10.56M | 0.1% | N/A | 6.269% | |
| 1/18/2018 | Acadian Asset Management LLC | 35,996 | $0.20M | 0.0% | +722.6% | 0.119% | |
| 1/17/2018 | Schwab Charles Investment Management Inc. | 110,872 | $0.62M | 0.0% | N/A | 0.365% | |
| 11/14/2017 | Orbimed Advisors LLC | 644,074 | $2.09M | 0.0% | -58.7% | 2.123% | |
| 11/13/2017 | Alpine Associates Management Inc. | 245,241 | $0.80M | 0.0% | N/A | 0.808% | |
| 11/13/2017 | Dimensional Fund Advisors LP | 436,003 | $1.42M | 0.0% | +6.9% | 1.437% | |
| 11/8/2017 | Granite Investment Partners LLC | 35,849 | $0.12M | 0.0% | -58.0% | 0.118% | |
| 11/8/2017 | Dynamic Technology Lab Private Ltd | 80,966 | $0.26M | 0.0% | N/A | 0.267% | |
| 11/6/2017 | Bank of New York Mellon Corp | 596,784 | $1.94M | 0.0% | +72.0% | 1.970% | |
| 11/6/2017 | Los Angeles Capital Management & Equity Research Inc. | 38,680 | $0.13M | 0.0% | N/A | 0.128% | |
