This company has been marked as potentially delisted and may not be actively trading. NASDAQ:PRNB Principia Biopharma (PRNB) Stock Price, News & Analysis Add Compare Share Share Stock Analysis Stock AnalysisBuy This Stock About Principia Biopharma Stock (NASDAQ:PRNB) Get Principia Biopharma alerts:Sign Up Key Stats Today's Range$100.05▼$100.0550-Day Range$99.95▼$100.2752-Week Range$25.35▼$101.89VolumeN/AAverage Volume729,676 shsMarket Capitalization$3.32 billionP/E RatioN/ADividend YieldN/APrice TargetN/AConsensus RatingN/A Company Overview Principia Biopharma Inc., a late-stage biopharmaceutical company, focuses on developing novel therapies for immunology and oncology. The company is developing PRN1008, an inhibitor that is in Phase III clinical trial for the treatment of pemphigus, a chronic skin disease, as well as in Phase II clinical trial to treat immune thrombocytopenic purpura. It is also developing PRN2246/SAR442168, an inhibitor, which has completed Phase I clinical trial for treating multiple sclerosis (MS) and other central nervous system (CNS) diseases; PRN1371, a drug candidate that is in Phase I clinical trial for the treatment of solid tumors; and oral small molecule inhibitors of the immunoproteasome. The company has a collaboration agreement with Genzyme Corporation to develop relapsing and progressive MS and other diseases of the CNS. Principia Biopharma Inc. was incorporated in 2008 and is headquartered in South San Francisco, California. Read More Receive PRNB Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Principia Biopharma and its competitors with MarketBeat's FREE daily newsletter. 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PRNB Stock News HeadlinesSports Final: Maty Mauk ready to coach Principia High SchoolApril 25, 2025 | msn.comFORE Biotherapeutics Names Michael Byrnes as Chief Financial OfficerAugust 12, 2024 | finance.yahoo.com2013 Bitcoin miner reveals his trading system (free)While everyone else is gambling on meme coins or chasing the next "100x moonshot," our members are systematically extracting profits from the $4 billion that changes hands in crypto every single day.September 17 at 2:00 AM | Crypto Swap Profits (Ad)Principia College names new presidentMay 28, 2023 | bizjournals.comCBI appoints ethics consultancy Principia Advisory in fight for survivalMay 5, 2023 | theguardian.comTruist Securities Downgrades 9 Meters Biopharma to Hold, Announces $38 Price TargetMarch 22, 2023 | benzinga.comWooly mammoth tusk discovered on Principia College campusJanuary 17, 2023 | msn.comDodge Construction Network Acquires Principia Consulting, Expanding Dodge Advisory Services’ CapabilitiesOctober 12, 2022 | finance.yahoo.comSee More Headlines PRNB Stock Analysis - Frequently Asked Questions How were Principia Biopharma's earnings last quarter? Principia Biopharma Inc. (NASDAQ:PRNB) issued its quarterly earnings results on Thursday, August, 6th. The company reported $0.31 earnings per share (EPS) for the quarter, beating the consensus estimate of ($1.03) by $1.34. The business earned $50 million during the quarter, compared to the consensus estimate of $50 million. When did Principia Biopharma IPO? Principia Biopharma (PRNB) raised $75 million in an initial public offering (IPO) on Friday, September 14th 2018. The company issued 4,700,000 shares at a price of $15.00-$17.00 per share. BofA Merrill Lynch, Leerink Partners and Wells Fargo Securities served as the underwriters for the IPO and Baird was co-manager. What other stocks do shareholders of Principia Biopharma own? Based on aggregate information from My MarketBeat watchlists, some other companies that Principia Biopharma investors own include Pfizer (PFE), Advanced Micro Devices (AMD), AbbVie (ABBV), Bristol Myers Squibb (BMY), Cisco Systems (CSCO), QUALCOMM (QCOM) and VBI Vaccines (VBIV). Company Calendar Last Earnings8/06/2020Today9/17/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry Pharmaceutical Preparations Sub-IndustryN/A Current SymbolNASDAQ:PRNB CIKN/A Webwww.principiabio.com Phone650-416-7700FaxN/AEmployees65Year FoundedN/AProfitability EPS (Trailing Twelve Months)($2.09) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$53.79 million Net MarginsN/A Pretax MarginN/A Return on Equity-23.08% Return on Assets-21.11% Debt Debt-to-Equity RatioN/A Current Ratio17.01 Quick Ratio17.01 Sales & Book Value Annual Sales$35.16 million Price / Sales94.50 Cash FlowN/A Price / Cash FlowN/A Book Value$10.95 per share Price / Book9.14Miscellaneous Outstanding Shares33,209,000Free FloatN/AMarket Cap$3.32 billion OptionableNot Optionable Beta0.86 The Best High-Yield Dividend Stocks for 2025Discover the 10 Best High-Yield Dividend Stocks for 2025 and secure reliable income in uncertain markets. Download the report now to identify top dividend payers and avoid common yield traps.Get This Free Report This page (NASDAQ:PRNB) was last updated on 9/17/2025 by MarketBeat.com Staff From Our PartnersTrump’s national nightmare is herePorter Stansberry and Jeff Brown say a new U.S. national emergency is already underway — and it could trigger ...Porter & Company | SponsoredHe Called Nvidia at $1.10. Now, He Says THIS Stock Will…The original Magnificent Seven returned 16,894%—turning $7K into $1.18 million. 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