Quantum-Si (QSI) Stock Price, News & Analysis

Company Overview

Quantum-Si Inc. is a life sciences instrumentation company headquartered in Guilford, Connecticut, developing next-generation proteomics solutions based on semiconductor sequencing technology. The company’s core offering centers on a proprietary single-molecule protein sequencing platform that uses a silicon-based sensor chip to convert protein data into digital signals. This approach is designed to deliver high sensitivity, single-amino-acid resolution and deep proteome coverage while potentially reducing cost and complexity compared to traditional mass spectrometry methods.

Quantum-Si’s product roadmap includes the development and commercialization of an integrated system comprising instruments, consumable reagents and proprietary data analysis software. By optimizing its chemical reagents and licensing its chip technology, the company seeks to enable researchers and biopharmaceutical developers to accelerate biomarker discovery, drug target validation and translational proteomics workflows. In addition to instrument sales, Quantum-Si offers research services and collaborative programs to demonstrate its platform in key disease-area applications.

Founded in 2017 by a team of scientists and entrepreneurs combining expertise in genomics and semiconductor engineering, Quantum-Si went public through a SPAC merger in mid-2021. Since inception, the company has invested in R&D facilities in Connecticut and established collaborations with academic laboratories and industry partners across North America and Europe. Its platform represents one of the first commercial efforts to leverage semiconductor-based detection for protein sequencing and proteomics research.

Under the leadership of President and Chief Executive Officer Steven Tignanelli—formerly CTO at Illumina—Quantum-Si is guided by a management team experienced in instrument development, bioinformatics and regulatory affairs. The company continues to expand manufacturing capabilities and pursue regulatory clearances with the goal of making advanced proteomic tools broadly accessible to research institutions and pharmaceutical companies worldwide.

Key Stats

• Today's Range: $2.26 to $2.53
• 50-Day Range: $1.00 to $2.63
• 52-Week Range: $0.61 to $5.77
• Volume: 20.83 million shs
• Average Volume: 19.12 million shs
• Market Capitalization: $461.68 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $3.48
• Consensus Rating: Hold

Quantum-Si Stock Analysis - MarketRank™

Quantum-Si scored higher than 52% of companies evaluated by MarketBeat, and ranked 419th out of 667 stocks in the computer and technology sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 3.5 / 5
• Analyst Rating: Hold

Consensus Rating

Quantum-Si has received a consensus rating of Hold. The company's average rating score is 2.25, and is based on 2 buy ratings, 1 hold rating, and 1 sell rating.

Upside Potential

Quantum-Si has a consensus price target of $3.48, representing about 52.4% upside from its current price of $2.28.

Amount of Analyst Coverage

Quantum-Si has only been the subject of 2 research reports in the past 90 days.

Earnings and Valuation

• Score: 0.0 / 5
• Proj. Earnings Growth: Decreasing

Earnings Growth

Earnings for Quantum-Si are expected to decrease in the coming year, from ($0.65) to ($0.75) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Quantum-Si is -3.35, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Quantum-Si is -3.35, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Quantum-Si has a P/B Ratio of 1.77. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.

Short Interest

• Score: 3.0 / 5
• Short Interest Level: Healthy

Percentage of Shares Shorted

14.07% of the float of Quantum-Si has been sold short.

Short Interest Ratio / Days to Cover

Quantum-Si has a short interest ratio ("days to cover") of 2.6, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Quantum-Si has recently decreased by 0.23%, indicating that investor sentiment is improving.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Quantum-Si does not currently pay a dividend.

Dividend Growth

Quantum-Si does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

14.07% of the float of Quantum-Si has been sold short.

Short Interest Ratio / Days to Cover

Quantum-Si has a short interest ratio ("days to cover") of 2.6, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Quantum-Si has recently decreased by 0.23%, indicating that investor sentiment is improving.

News and Social Media

• Score: 3.1 / 5
• News Sentiment: 0.50

News Sentiment

Quantum-Si has a news sentiment score of 0.50. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This news sentiment score is similar to the average news sentiment of Computer and Technology companies.

News Coverage This Week

MarketBeat has tracked 11 news articles for Quantum-Si this week, compared to 3 articles on an average week.

Search Interest

55 people have searched for QSI on MarketBeat in the last 30 days. This is an increase of 206% compared to the previous 30 days.

MarketBeat Follows

15 people have added Quantum-Si to their MarketBeat watchlist in the last 30 days. This is an increase of 275% compared to the previous 30 days.

Company Ownership

• Score: 2.5 / 5
• Insider Trading: Selling Shares

Insider Buying vs. Insider Selling

In the past three months, Quantum-Si insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $152,085.00 in company stock.

Percentage Held by Insiders

30.04% of the stock of Quantum-Si is held by insiders. A high percentage of insider ownership can be a sign of company health.

Percentage Held by Institutions

Only 39.90% of the stock of Quantum-Si is held by institutions.

QSI Stock Analysis - Frequently Asked Questions

How have QSI shares performed this year?

Quantum-Si's stock was trading at $2.70 at the start of the year. Since then, QSI stock has decreased by 15.6% and is now trading at $2.28.

How were Quantum-Si's earnings last quarter?

Quantum-Si Incorporated (NASDAQ:QSI) released its earnings results on Tuesday, August, 5th. The company reported ($0.16) EPS for the quarter, hitting analysts' consensus estimates of ($0.16). The firm earned $0.59 million during the quarter, compared to the consensus estimate of $1.28 million. Quantum-Si had a negative trailing twelve-month return on equity of 44.57% and a negative net margin of 3,120.14%.
Read the conference call transcript.

Who are Quantum-Si's major shareholders?

Top institutional shareholders of Quantum-Si include Green Alpha Advisors LLC (0.11%), Voya Investment Management LLC (0.01%), HBK Sorce Advisory LLC (0.01%) and HBK Sorce Advisory LLC (0.01%). Insiders that own company stock include Jeffrey Alan Hawkins, Jonathan M Rothberg, Jeffry R Keyes, John S Vieceli, Todd C Bennett, Christian Lapointe, Charles R Kummeth and Grace Johnston.
View institutional ownership trends.

How do I buy shares of Quantum-Si?

Shares of QSI stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Quantum-Si own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Quantum-Si investors own include Digital Turbine (APPS), Archer Aviation (ACHR), SoFi Technologies (SOFI), ChargePoint (CHPT) and Canoo (GOEV).

Company Calendar

• Last Earnings: 8/05/2025
• Today: 10/19/2025
• Next Earnings (Confirmed): 11/05/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Computer and Technology
• Industry: ELEC COMP - SEMIC
• Sub-Industry: Measuring And Control Equipment
• Current Symbol: NASDAQ:QSI
• CIK: 1816431
• Web: www.quantum-si.com
• Phone: 866-688-7374
• Fax: N/A
• Employees: 150
• Year Founded: N/A

Price Target and Rating

• Average Price Target for Quantum-Si: $3.48
• High Price Target: $5.50
• Low Price Target: $1.00
• Potential Upside/Downside: +52.4%
• Consensus Rating: Hold
• Rating Score (0-4): 2.25
• Research Coverage: 4 Analysts

Profitability

• EPS (Trailing Twelve Months): ($0.68)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$101.01 million
• Net Margins: -3,120.14%
• Pretax Margin: -3,117.58%
• Return on Equity: -44.57%
• Return on Assets: -39.45%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 9.43
• Quick Ratio: 9.27

Sales & Book Value

• Annual Sales: $3.06 million
• Price / Sales: 150.87
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $1.29 per share
• Price / Book: 1.77

Miscellaneous

• Outstanding Shares: 202,490,000
• Free Float: 141,666,000
• Market Cap: $461.68 million
• Optionable: Optionable
• Beta: 2.89