| 2/23/2026 | Virtu Financial LLC | 15,488 | $40K | 0.0% | N/A | 0.036% | |
| 2/18/2026 | XTX Topco Ltd | 116,933 | $304K | 0.0% | +145.9% | 0.271% | |
| 2/18/2026 | Occudo Quantitative Strategies LP | 13,548 | $35K | 0.0% | N/A | 0.031% | |
| 2/16/2026 | Squarepoint Ops LLC | 14,485 | $38K | 0.0% | -77.8% | 0.034% | |
| 2/16/2026 | Yakira Capital Management Inc. | 266,601 | $693K | 0.2% | N/A | 0.618% | |
| 2/13/2026 | Marshall Wace LLP | 1,115,744 | $2.90M | 0.0% | N/A | 2.588% | |
| 2/13/2026 | Walleye Capital LLC | 106,683 | $277K | 0.0% | N/A | 0.247% | |
| 2/13/2026 | Stifel Financial Corp | 10,000 | $26K | 0.0% | -87.1% | 0.023% | |
| 2/12/2026 | HRT Financial LP | 42,301 | $109K | 0.0% | N/A | 0.098% | |
| 2/12/2026 | StoneX Group Inc. | 10,603 | $28K | 0.0% | N/A | 0.025% | |
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| 2/12/2026 | Renaissance Technologies LLC | 981,360 | $2.55M | 0.0% | +35.5% | 2.277% | |
| 2/6/2026 | Covestor Ltd | 13,627 | $35K | 0.0% | N/A | 0.032% | |
| 1/16/2026 | FNY Investment Advisers LLC | 35,000 | $91K | 0.0% | N/A | 0.081% | |
| 11/26/2025 | Lantern Wealth Advisors LLC | 20,000 | $35K | 0.0% | N/A | 0.046% | |
| 11/17/2025 | Citadel Advisors LLC | 699,297 | $1.23M | 0.0% | -26.6% | 1.628% | |
| 11/14/2025 | Squarepoint Ops LLC | 65,243 | $115K | 0.0% | N/A | 0.152% | |
| 8/15/2025 | Rangeley Capital LLC | 355,292 | $494K | 0.6% | N/A | 0.827% | |
| 8/15/2025 | Militia Capital Partners LP | 119,176 | $166K | 0.1% | N/A | 0.277% | |
| 8/14/2025 | Redmile Group LLC | 1,586,174 | $2.21M | 0.2% | -15.8% | 3.692% | |
| 8/12/2025 | XTX Topco Ltd | 43,174 | $60K | 0.0% | N/A | 0.101% | |
| 8/8/2025 | Quinn Opportunity Partners LLC | 40,000 | $56K | 0.0% | N/A | 0.093% | |
| 5/21/2025 | Acadian Asset Management LLC | 640,332 | $624K | 0.0% | +35.6% | 1.493% | |
| 5/15/2025 | Redmile Group LLC | 1,884,389 | $1.86M | 0.2% | -1.7% | 4.393% | |
| 5/15/2025 | MPM Bioimpact LLC | 819,924 | $808K | 0.1% | -33.4% | 1.912% | |
| 5/15/2025 | MPM Asset Management LLC | 1,121,318 | $1.11M | 1.6% | -33.4% | 2.614% | |
| 5/14/2025 | Affinity Asset Advisors LLC | 200,000 | $197K | 0.0% | +100.0% | 0.466% | |
| 5/7/2025 | ARK Investment Management LLC | 1,124,483 | $1.11M | 0.0% | -43.8% | 2.622% | |
| 2/17/2025 | Redmile Group LLC | 1,916,089 | $2.51M | 0.2% | -1.4% | 4.507% | |
| 2/17/2025 | MPM Asset Management LLC | 1,683,707 | $2.21M | 1.8% | -24.9% | 3.961% | |
| 2/17/2025 | MPM Bioimpact LLC | 1,231,154 | $1.61M | 0.2% | -24.9% | 2.896% | |
| 2/17/2025 | Millennium Management LLC | 170,959 | $224K | 0.0% | +65.5% | 0.402% | |
| 2/14/2025 | Lynx1 Capital Management LP | 79,176 | $104K | 0.0% | N/A | 0.186% | |
| 2/14/2025 | Blue Owl Capital Holdings LP | 3,443,659 | $4.51M | 1.1% | +2.1% | 8.101% | |
| 2/14/2025 | Stifel Financial Corp | 89,500 | $117K | 0.0% | +73.1% | 0.211% | |
| 2/14/2025 | Tower Research Capital LLC TRC | 34,423 | $45K | 0.0% | +204.7% | 0.081% | |
| 2/13/2025 | Marshall Wace LLP | 46,876 | $61K | 0.0% | -60.6% | 0.110% | |
| 2/13/2025 | Affinity Asset Advisors LLC | 100,000 | $131K | 0.0% | -42.3% | 0.235% | |
| 2/13/2025 | Renaissance Technologies LLC | 347,460 | $455K | 0.0% | -23.4% | 0.817% | |
| 2/12/2025 | JPMorgan Chase & Co. | 85,802 | $112K | 0.0% | +2,144,950.0% | 0.202% | |
| 2/10/2025 | Nikko Asset Management Americas Inc. | 116,249 | $152K | 0.0% | -53.4% | 0.273% | |
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| 2/4/2025 | ARK Investment Management LLC | 1,999,997 | $2.62M | 0.0% | -20.3% | 4.705% | |
| 1/30/2025 | Vontobel Holding Ltd. | 35,000 | $46K | 0.0% | +45.8% | 0.082% | |
| 1/28/2025 | Sumitomo Mitsui Trust Group Inc. | 116,249 | $152K | 0.0% | -53.4% | 0.273% | |
| 11/19/2024 | Barclays PLC | 8,330 | $29K | 0.0% | +1,471.7% | 0.020% | |
| 11/15/2024 | Barclays PLC | 8,330 | $29K | 0.0% | +1,471.7% | 0.020% | |
| 11/15/2024 | Stifel Financial Corp | 51,700 | $178K | 0.0% | +36.4% | 0.122% | |
| 11/5/2024 | Sumitomo Mitsui Trust Group Inc. | 249,215 | $857K | 0.0% | -10.1% | 0.587% | |
| 11/5/2024 | GSA Capital Partners LLP | 240,522 | $827K | 0.1% | -19.7% | 0.567% | |
| 10/31/2024 | ARK Investment Management LLC | 2,509,737 | $8.63M | 0.1% | -4.6% | 5.913% | |
| 10/16/2024 | Vontobel Holding Ltd. | 24,000 | $83K | 0.0% | +20.0% | 0.057% | |
| 10/10/2024 | Exchange Traded Concepts LLC | 50,441 | $174K | 0.0% | +21.2% | 0.119% | |
| 8/15/2024 | Blue Owl Capital Holdings LP | 3,372,499 | $11.13M | 3.1% | +8.0% | 7.945% | |
| 8/14/2024 | Squarepoint Ops LLC | 142,974 | $472K | 0.0% | +428.4% | 0.337% | |
| 8/14/2024 | Marshall Wace LLP | 82,590 | $273K | 0.0% | N/A | 0.195% | |
| 8/14/2024 | Bank of Montreal Can | 110,935 | $366K | 0.0% | +5.4% | 0.261% | |
| 8/12/2024 | XTX Topco Ltd | 33,320 | $110K | 0.0% | N/A | 0.079% | |
| 8/9/2024 | Renaissance Technologies LLC | 458,700 | $1.51M | 0.0% | +30.7% | 1.081% | |
| 8/9/2024 | Dimensional Fund Advisors LP | 13,265 | $44K | 0.0% | -67.5% | 0.031% | |
| 8/6/2024 | Acadian Asset Management LLC | 417,929 | $1.37M | 0.0% | +212.1% | 0.985% | |
| 7/26/2024 | ARK Investment Management LLC | 2,630,364 | $8.68M | 0.1% | -2.7% | 6.198% | |
| 7/19/2024 | Sumitomo Mitsui Trust Holdings Inc. | 277,168 | $915K | 0.0% | -10.1% | 0.653% | |
| 5/29/2024 | Opaleye Management Inc. | 67,561 | $318K | 0.1% | N/A | 0.159% | |
| 5/16/2024 | Redmile Group LLC | 2,016,302 | $9.50M | 0.3% | -6.2% | 4.751% | |
| 5/10/2024 | Acadian Asset Management LLC | 133,893 | $625K | 0.0% | +53.5% | 0.315% | |
| 5/3/2024 | GSA Capital Partners LLP | 126,208 | $594K | 0.0% | -12.6% | 0.297% | |
| 5/3/2024 | Nikko Asset Management Americas Inc. | 308,449 | $1.43M | 0.0% | -5.4% | 0.727% | |
| 4/19/2024 | Sumitomo Mitsui Trust Holdings Inc. | 308,449 | $1.45M | 0.0% | -5.4% | 0.834% | |
| 2/15/2024 | BVF Inc. IL | 10,333,600 | $75.44M | 1.9% | +24.6% | 24.528% | |
| 2/7/2024 | Jump Financial LLC | 39,603 | $289K | 0.0% | N/A | 0.094% | |
| 2/6/2024 | SRS Capital Advisors Inc. | 10,000 | $73K | 0.0% | +100.0% | 0.024% | |
| 1/30/2024 | Vontobel Holding Ltd. | 15,000 | $110K | 0.0% | N/A | 0.036% | |
| 1/17/2024 | ARK Investment Management LLC | 2,821,560 | $20.60M | 0.1% | +7.7% | 6.697% | |
| 1/8/2024 | Harbor Capital Advisors Inc. | 48,055 | $351K | 0.1% | +14.2% | 0.114% | |
| 1/5/2024 | Exchange Traded Concepts LLC | 13,585 | $99K | 0.0% | +34.0% | 0.032% | |
| 11/15/2023 | Redmile Group LLC | 2,404,695 | $29.05M | 1.4% | -1.0% | 5.708% | |
| 11/14/2023 | Blackstone Inc. | 25,957 | $314K | 0.0% | +14.9% | 0.062% | |
| 11/14/2023 | Trexquant Investment LP | 29,456 | $356K | 0.0% | -47.3% | 0.070% | |
| 11/13/2023 | Connor Clark & Lunn Investment Management Ltd. | 14,919 | $180K | 0.0% | +30.6% | 0.035% | |
| 11/13/2023 | FMR LLC | 1,079,847 | $13.05M | 0.0% | -7.6% | 2.563% | |
| 10/30/2023 | Sumitomo Mitsui Trust Holdings Inc. | 326,011 | $3.94M | 0.0% | +1.1% | 0.775% | |
| 10/24/2023 | Raymond James Financial Services Advisors Inc. | 12,357 | $149K | 0.0% | N/A | 0.029% | |
| 10/20/2023 | Harbor Capital Advisors Inc. | 42,085 | $508K | 0.1% | +13.8% | 0.100% | |
| 10/18/2023 | ARK Investment Management LLC | 2,620,883 | $31.66M | 0.2% | -0.3% | 6.227% | |
| 9/21/2023 | Barclays PLC | 3,409 | $36K | 0.0% | N/A | 0.008% | |
| 8/11/2023 | Hershey Trust Co. | 5,883 | $62K | 0.0% | N/A | 0.014% | |
| 8/11/2023 | Trexquant Investment LP | 55,932 | $592K | 0.0% | -36.5% | 0.133% | |
| 8/9/2023 | Versant Venture Management LLC | 2,646,657 | $28.00M | 33.2% | N/A | 6.288% | |
| 8/8/2023 | Candriam S.C.A. | 50,001 | $529K | 0.0% | N/A | 0.119% | |
| 8/7/2023 | Acadian Asset Management LLC | 81,629 | $860K | 0.0% | -3.1% | 0.194% | |
| 8/2/2023 | Bank of Montreal Can | 117,824 | $1.47M | 0.0% | N/A | 0.280% | |
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| 7/31/2023 | Sumitomo Mitsui Trust Holdings Inc. | 322,616 | $3.41M | 0.0% | +99.6% | 0.766% | |
| 7/25/2023 | DekaBank Deutsche Girozentrale | 40,000 | $430K | 0.0% | +174.0% | 0.095% | |
| 7/20/2023 | Exchange Traded Concepts LLC | 11,445 | $121K | 0.0% | N/A | 0.027% | |
| 7/11/2023 | Harbor Capital Advisors Inc. | 36,984 | $391K | 0.1% | +10.0% | 0.088% | |
| 7/10/2023 | ARK Investment Management LLC | 2,628,073 | $27.81M | 0.2% | -4.0% | 6.244% | |
| 5/15/2023 | Sio Capital Management LLC | 228,538 | $2.25M | 1.1% | N/A | 0.543% | |
| 5/11/2023 | Acadian Asset Management LLC | 84,273 | $826K | 0.0% | +222.1% | 0.200% | |
| 5/11/2023 | CHI Advisors LLC | 2,997,939 | $29.50M | 7.8% | +7.1% | 7.124% | |
| 5/9/2023 | Tower Research Capital LLC TRC | 11,316 | $111K | 0.0% | +533.2% | 0.027% | |
| 5/3/2023 | Nikko Asset Management Americas Inc. | 161,598 | $1.47M | 0.0% | -7.1% | 0.384% | |