Sorrento Therapeutics, Inc. (NASDAQ: SRNE) is a clinical-stage biopharmaceutical company focused on developing therapies for oncology, autoimmune disorders, and inflammatory pain. Founded in 2006 and headquartered in San Diego, California, the firm leverages proprietary platforms to create targeted treatments that harness the power of antibodies, cell therapies, and small molecules. Its diversified pipeline includes antibody-drug conjugates (ADCs), chimeric antigen receptor (CAR) T-cell therapies, and immunomodulators designed to address unmet medical needs.
The company’s lead programs span multiple stages of clinical development. Sorrento’s ADC platform aims to deliver potent cytotoxic agents directly to tumor cells while minimizing systemic exposure, and its CAR-T portfolio targets hematological malignancies with next-generation constructs engineered for enhanced safety and efficacy. In addition to oncology, the company is advancing non-opioid pain management therapies, including cannabinoid-based formulations and small molecules that modulate inflammatory pathways.
Sorrento has expanded its global footprint through strategic collaborations, research partnerships, and acquisitions. The company maintains research laboratories and manufacturing sites in the United States and China, enabling cross-border development and regulatory initiatives. Collaborative agreements with academic institutions and biopharmaceutical partners support translational research and aim to accelerate the progression of its lead assets toward approval.
Under the leadership of founder and Chief Executive Officer Henry Ji, Ph.D., Sorrento’s executive team brings together seasoned experts in drug discovery, clinical operations, regulatory affairs, and commercial strategy. The board of directors features industry veterans who have overseen pivotal clinical trials and successful product launches. Looking ahead, the company plans to advance its clinical pipeline, deepen strategic alliances, and ultimately deliver novel therapies to patients worldwide.
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