Syros Pharmaceuticals (SYRS) Institutional Ownership $0.02 0.00 (-5.49%) As of 11:27 AM Eastern Add Compare Share Share Ownership Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock Institutional Ownership Changes (13F Filings) for Syros Pharmaceuticals (NASDAQ:SYRS)CurrentInstitutional OwnershipPercentage91.47%Number ofInstitutional Buyers(last 12 months)5TotalInstitutional Inflows(last 12 months)$557.93KNumber ofInstitutional Sellers(last 12 months)3TotalInstitutional Outflows(last 12 months)$1.24M Get SYRS Insider Trade Alerts Want to know when executives and insiders are buying or selling Syros Pharmaceuticals stock? Sign up for InsiderTrades.com's daily newsletter to get the latest insider transactions delivered to your inbox daily. Email Address Skip Chart & View Institutional Buying and Selling Data SYRS Institutional Buying and Selling by Quarter Syros Pharmaceuticals Major Shareholders & Ownership History Export to ExcelReporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails2/14/2025 Two Sigma Securities LLC107,742$25K0.0%N/A0.402% 12/13/2024 Exome Asset Management LLC298,575$642K0.4%+87.6%1.113% 11/14/2024 Walleye Capital LLC86,641$186K0.0%-69.7%0.323% 11/5/2024 GSA Capital Partners LLP15,905$34K0.0%N/A0.059% 8/9/2024 Renaissance Technologies LLC117,435$606K0.0%-2.0%0.438% 8/6/2024 Certuity LLC21,202$109K0.0%N/A0.079% 8/6/2024 Acadian Asset Management LLC34,578$178K0.0%+101.5%0.129% 7/18/2024 Assenagon Asset Management S.A.15,873$82K0.0%-90.7%0.059% 5/29/2024 Opaleye Management Inc.787,545$4.21M0.9%+119.1%2.947% 5/20/2024 Virtu Financial LLC12,030$64K0.0%N/A0.045% Get the Latest News and Ratings for SYRS and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Syros Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. 5/16/2024 Kennedy Capital Management LLC404,914$2.17M0.0%N/A1.515% 5/10/2024 Acadian Asset Management LLC17,162$91K0.0%N/A0.064% 5/10/2024 Vanguard Group Inc.928,046$4.97M0.0%+21.3%3.472% 4/24/2024 Assenagon Asset Management S.A.169,999$909K0.0%+576.5%0.636% 2/15/2024 Opaleye Management Inc.359,370$2.80M0.7%N/A1.706% 2/15/2024 Flagship Pioneering Inc.1,293,848$10.08M0.8%+30.2%6.141% 2/14/2024 Avidity Partners Management LP1,673,538$13.04M0.5%+5.8%7.943% 2/13/2024 Bain Capital Life Sciences Investors LLC2,749,808$21.42M2.1%+29.4%13.051% 11/14/2023 Avidity Partners Management LP1,581,142$6.25M0.3%+8.0%7.635% 11/13/2023CHI Advisors LLC1,299,359$5.12M1.5%+69.3%6.274% 11/6/2023 Assenagon Asset Management S.A.25,130$99K0.0%+142.2%0.121% 10/19/2023 Clarius Group LLC18,620$74K0.0%N/A0.090% 8/14/2023 Shay Capital LLC26,426$83K0.0%+87.3%0.128% 8/11/2023 ExodusPoint Capital Management LP118,398$373K0.0%-2.6%0.572% 5/16/2023 Ally Bridge Group NY LLC249,126$665K0.9%-71.3%1.210% 5/11/2023CHI Advisors LLC767,445$2.05M0.5%N/A3.760% 4/18/2023 Assenagon Asset Management S.A.10,376$28K0.0%N/A0.051% 2/9/2023 Denali Advisors LLC7,700$28K0.0%N/A0.038% 11/15/2022 Flagship Pioneering Inc.993,848$6.40M0.3%-66.2%15.775% 11/15/2022 Bain Capital Life Sciences Investors LLC1,082,404$6.97M0.8%-82.7%17.181% 11/9/2022 Edmond DE Rothschild Holding S.A.4,382$28K0.0%N/A0.070% 10/24/2022 Clarius Group LLC19,347$125K0.0%-90.0%0.307% 10/13/2022 LGT Capital Partners LTD.55,000$354K0.0%-90.0%0.873% 8/11/2022 Artal Group S.A.4,000,000$3.85M0.2%+14.3%6.367% 8/10/2022 Clarius Group LLC193,483$186K0.0%N/A0.308% 7/19/2022Sawtooth Solutions LLC42,286$41K0.0%+76.5%0.067% 7/13/2022 LGT Capital Partners LTD.550,000$529K0.0%+10.0%0.876% 7/13/2022 Private Advisor Group LLC51,437$50K0.0%+112.9%0.082% 5/16/2022 Ally Bridge Group NY LLC3,364,895$4.00M3.0%-4.9%5.420% 5/12/2022 Artal Group S.A.3,500,000$4.17M0.2%+16.7%5.638% New Rule Hits in July — The Smart Money Already Moved (Ad)A little-known regulation quietly goes into effect this July. 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We're talking about something they don't want you to notice — because the fewer people who act on this, the better it is for them.To help you get started, we're giving away a FREE Wealth Protection Guide that shows you exactly how5/12/2022 Connor Clark & Lunn Investment Management Ltd.137,156$163K0.0%+15.6%0.221% 5/11/2022ACT Capital Management LLC35,000$42K0.0%+62.8%0.056% 5/11/2022 GSA Capital Partners LLP372,208$443K0.1%+53.7%0.600% 2/15/2022 Adage Capital Partners GP L.L.C.1,900,000$6.19M0.0%+5.6%3.067% 2/14/2022 Altium Capital Management LP1,160,000$3.78M1.0%-8.8%1.873% 2/14/2022 GSA Capital Partners LLP242,132$789K0.1%+119.4%0.391% 2/14/2022 Ally Bridge Group NY LLC3,539,895$11.54M4.0%+2.9%5.714% 2/11/2022 Ensign Peak Advisors Inc45,000$147K0.0%-55.0%0.073% 2/10/2022 Connor Clark & Lunn Investment Management Ltd.118,632$387K0.0%+14.8%0.192% 2/7/2022 SG Americas Securities LLC12,012$39K0.0%-61.4%0.019% 2/3/2022ACT Capital Management LLC21,500$70K0.1%-59.0%0.035% 1/14/2022 LGT Capital Partners LTD.500,000$1.63M0.0%+1,052.4%0.807% 11/17/2021 Altium Capital Management LP1,272,412$5.69M1.3%+18.2%2.054% 11/16/2021 Two Sigma Advisers LP172,700$772K0.0%-32.6%0.279% 11/16/2021 Two Sigma Investments LP91,278$408K0.0%-24.2%0.147% 11/16/2021 Metropolitan Life Insurance Co NY16,415$73K0.0%N/A0.026% 11/15/2021 Point72 Hong Kong Ltd7,062$32K0.0%+168.8%0.011% 11/15/2021 Cubist Systematic Strategies LLC86,990$389K0.0%-66.3%0.140% 11/15/2021 Marshall Wace LLP183,451$820K0.0%-38.1%0.296% 11/15/2021 Franklin Resources Inc.64,000$286K0.0%N/A0.103% 11/15/2021 GSA Capital Partners LLP110,337$493K0.1%-21.7%0.178% 11/12/2021 Trexquant Investment LP30,162$135K0.0%-10.4%0.049% 11/12/2021 Geode Capital Management LLC857,646$3.83M0.0%-11.3%1.384% 11/12/2021 Artal Group S.A.2,000,000$8.94M0.2%+17.6%3.229% 11/12/2021 Connor Clark & Lunn Investment Management Ltd.103,307$462K0.0%+35.8%0.167% 11/10/2021 Goldman Sachs Group Inc.490,501$2.19M0.0%-2.1%0.792% 11/10/2021 Citigroup Inc.9,702$43K0.0%+49.5%0.016% 11/9/2021 Barclays PLC44,863$200K0.0%-23.7%0.072% 11/9/2021BlackRock Inc.4,353,672$19.46M0.0%-2.5%7.030% 11/9/2021 Ieq Capital LLC27,800$124K0.0%N/A0.045% 11/8/2021 Summit Global Investments31,800$142K0.0%N/A0.051% 11/8/2021 State Board of Administration of Florida Retirement System78,535$351K0.0%+233.0%0.127% 11/8/2021 Russell Investments Group Ltd.10,289$45K0.0%-49.4%0.017% 11/8/2021 Los Angeles Capital Management LLC258,938$1.16M0.0%-4.6%0.418% 11/4/2021 Deutsche Bank AG59,973$268K0.0%+65.9%0.097% 11/1/2021 SG Americas Securities LLC31,096$139K0.0%N/A0.050% 10/19/2021 Assenagon Asset Management S.A.87,073$389K0.0%-24.8%0.141% 10/13/2021 LGT Capital Partners LTD.43,388$194K0.0%N/A0.070% 9/3/2021Parametric Portfolio Associates LLC19,110$104K0.0%N/A0.031% 8/25/2021 Marshall Wace LLP296,405$1.62M0.0%N/A0.479% 8/17/2021 Millennium Management LLC557,713$3.04M0.0%+230.4%0.901% 8/17/2021 Caas Capital Management LP13,905$76K0.0%N/A0.022% 8/16/2021 PDT Partners LLC116,801$637K0.0%-20.8%0.189% 8/16/2021 Cubist Systematic Strategies LLC257,997$1.41M0.0%+891.3%0.417% 8/16/2021 Redmile Group LLC38,912$212K0.0%-81.7%0.063% 8/16/2021 California State Teachers Retirement System79,478$433K0.0%+11.7%0.128% 8/16/2021 Charles Schwab Investment Management Inc.391,798$2.14M0.0%+7.9%0.633% 8/16/2021 State Street Corp999,254$5.45M0.0%+25.6%1.613% 8/16/2021Nuveen Asset Management LLC180,514$984K0.0%+23.1%0.291% 8/16/2021 Omega Fund Management LLC2,274,831$12.40M2.1%+45.6%3.673% Banks aren’t ready for this altcoin—are you? (Ad)While everyone's distracted by Bitcoin's moves, a stealth revolution is underway. One altcoin is quietly positioning itself to overthrow the entire banking system.Click here to access the full report now.8/16/2021 Goldman Sachs Group Inc.501,221$2.73M0.0%-21.3%0.809% 8/16/2021 Marshall Wace LLP296,405$1.62M0.0%N/A0.479% 8/13/2021 Northern Trust Corp554,422$3.02M0.0%+6.6%0.895% 8/13/2021 Altium Capital Management LP1,076,942$5.87M1.4%+750.0%1.739% 8/13/2021 LPL Financial LLC38,090$208K0.0%+97.1%0.062% 8/13/2021 Qube Research & Technologies Ltd78,774$429K0.0%+115.9%0.127% 8/13/2021 Geode Capital Management LLC966,448$5.27M0.0%+16.0%1.561% 8/13/2021 Vanguard Group Inc.2,775,576$15.13M0.0%+1.6%4.482% 8/13/2021 FMR LLC9,047,965$49.31M0.0%+0.4%14.610% 8/13/2021 ProShare Advisors LLC26,050$142K0.0%+23.3%0.042% (Data available from 1/1/2016 forward) SYRS Institutional Ownership - Frequently Asked Questions Who are the largest shareholders of SYRS shares? During the previous two years, 19 institutional investors and hedge funds held shares of Syros Pharmaceuticals. The most heavily invested institutionals were Bain Capital Life Sciences Investors LLC ($21.42M), Avidity Partners Management LP ($13.04M), Flagship Pioneering Inc. ($10.08M), CHI Advisors LLC ($5.12M), Vanguard Group Inc. ($4.97M), Opaleye Management Inc. ($4.21M), and Kennedy Capital Management LLC ($2.17M).Learn more on SYRS's institutional investors. What percentage of Syros Pharmaceuticals stock is owned by institutional investors? 91.47% of Syros Pharmaceuticals stock is owned by institutional investors. Learn more on SYRS's institutional investor holdings. Which institutional investors have been buying Syros Pharmaceuticals stock? Of the 16 institutional investors that purchased Syros Pharmaceuticals stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Opaleye Management Inc. ($787.55K), Bain Capital Life Sciences Investors LLC ($625.11K), CHI Advisors LLC ($531.91K), Kennedy Capital Management LLC ($404.91K), Flagship Pioneering Inc. ($300K), Avidity Partners Management LP ($209.50K), and Vanguard Group Inc. ($163.23K). How much institutional buying is happening at Syros Pharmaceuticals? Institutional investors have bought a total of 3,543,642 shares in the last 24 months. This purchase volume represents approximately $20.28M in transactions. Which Syros Pharmaceuticals major shareholders have been selling company stock? The following institutional investors have sold Syros Pharmaceuticals stock in the last 24 months: Walleye Capital LLC ($199.16K), Assenagon Asset Management S.A. ($154.13K), ExodusPoint Capital Management LP ($3.16K), and Renaissance Technologies LLC ($2.40K). How much institutional selling is happening at Syros Pharmaceuticals? Institutional investors have sold a total of 358,845 shares in the last 24 months. This volume of shares sold represents approximately $1.25M in transactions. Related Companies SPRC Major Shareholders GENE Major Shareholders PWUP Major Shareholders VRAX Major Shareholders CDT Major Shareholders ZVSA Major Shareholders ENVB Major Shareholders ELAB Major Shareholders AFMD Major Shareholders QLGN Major Shareholders This page (NASDAQ:SYRS) was last updated on 6/12/2025 by MarketBeat.com Staff From Our PartnersTrump’s Exec Order #14154 could be a “Millionaire-Maker”Former Presidential Advisor, Jim Rickards, says Trump could “rewire our economy and hand millions of Americans...Paradigm Press | SponsoredTrump wipes out trillions overnight…Is there anybody more powerful than Donald Trump right now? In a single tariff announcement, he wiped out n...Porter & Company | SponsoredGold is soaring. 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