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Syros Pharmaceuticals (SYRS) Institutional Ownership

Syros Pharmaceuticals logo
$0.0027 -0.01 (-84.66%)
As of 07/9/2025 03:59 PM Eastern
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Institutional Ownership Changes (13F Filings) for Syros Pharmaceuticals (NASDAQ:SYRS)

Current
Institutional Ownership
Percentage
91.47%
Number of
Institutional Buyers
(last 12 months)
5
Total
Institutional Inflows
(last 12 months)
$557.93K
Number of
Institutional Sellers
(last 12 months)
3
Total
Institutional Outflows
(last 12 months)
$1.24M
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SYRS Institutional Buying and Selling by Quarter

Syros Pharmaceuticals Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
2/14/2025Two Sigma Securities LLC107,742$25K0.0%N/A0.402%
12/13/2024Exome Asset Management LLC298,575$642K0.4%+87.6%1.113%
11/14/2024Walleye Capital LLC86,641$186K0.0%-69.7%0.323%
11/5/2024GSA Capital Partners LLP15,905$34K0.0%N/A0.059%
8/9/2024Renaissance Technologies LLC117,435$606K0.0%-2.0%0.438%
8/6/2024Certuity LLC21,202$109K0.0%N/A0.079%
8/6/2024Acadian Asset Management LLC34,578$178K0.0%+101.5%0.129%
7/18/2024Assenagon Asset Management S.A.15,873$82K0.0%-90.7%0.059%
5/29/2024Opaleye Management Inc.787,545$4.21M0.9%+119.1%2.947%
5/20/2024Virtu Financial LLC12,030$64K0.0%N/A0.045%
5/16/2024Kennedy Capital Management LLC404,914$2.17M0.0%N/A1.515%
5/10/2024Acadian Asset Management LLC17,162$91K0.0%N/A0.064%
5/10/2024Vanguard Group Inc.928,046$4.97M0.0%+21.3%3.472%
4/24/2024Assenagon Asset Management S.A.169,999$909K0.0%+576.5%0.636%
2/15/2024Opaleye Management Inc.359,370$2.80M0.7%N/A1.706%
2/15/2024Flagship Pioneering Inc.1,293,848$10.08M0.8%+30.2%6.141%
2/14/2024Avidity Partners Management LP1,673,538$13.04M0.5%+5.8%7.943%
2/13/2024Bain Capital Life Sciences Investors LLC2,749,808$21.42M2.1%+29.4%13.051%
11/14/2023Avidity Partners Management LP1,581,142$6.25M0.3%+8.0%7.635%
11/13/2023CHI Advisors LLC1,299,359$5.12M1.5%+69.3%6.274%
11/6/2023Assenagon Asset Management S.A.25,130$99K0.0%+142.2%0.121%
10/19/2023Clarius Group LLC18,620$74K0.0%N/A0.090%
8/14/2023Shay Capital LLC26,426$83K0.0%+87.3%0.128%
8/11/2023ExodusPoint Capital Management LP118,398$373K0.0%-2.6%0.572%
5/16/2023Ally Bridge Group NY LLC249,126$665K0.9%-71.3%1.210%
5/11/2023CHI Advisors LLC767,445$2.05M0.5%N/A3.760%
4/18/2023Assenagon Asset Management S.A.10,376$28K0.0%N/A0.051%
2/9/2023Denali Advisors LLC7,700$28K0.0%N/A0.038%
11/15/2022Flagship Pioneering Inc.993,848$6.40M0.3%-66.2%15.775%
11/15/2022Bain Capital Life Sciences Investors LLC1,082,404$6.97M0.8%-82.7%17.181%
11/9/2022Edmond DE Rothschild Holding S.A.4,382$28K0.0%N/A0.070%
10/24/2022Clarius Group LLC19,347$125K0.0%-90.0%0.307%
10/13/2022LGT Capital Partners LTD.55,000$354K0.0%-90.0%0.873%
8/11/2022Artal Group S.A.4,000,000$3.85M0.2%+14.3%6.367%
8/10/2022Clarius Group LLC193,483$186K0.0%N/A0.308%
7/19/2022Sawtooth Solutions LLC42,286$41K0.0%+76.5%0.067%
7/13/2022LGT Capital Partners LTD.550,000$529K0.0%+10.0%0.876%
7/13/2022Private Advisor Group LLC51,437$50K0.0%+112.9%0.082%
5/16/2022Ally Bridge Group NY LLC3,364,895$4.00M3.0%-4.9%5.420%
5/12/2022Artal Group S.A.3,500,000$4.17M0.2%+16.7%5.638%
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5/12/2022Connor Clark & Lunn Investment Management Ltd.137,156$163K0.0%+15.6%0.221%
5/11/2022ACT Capital Management LLC35,000$42K0.0%+62.8%0.056%
5/11/2022GSA Capital Partners LLP372,208$443K0.1%+53.7%0.600%
2/15/2022Adage Capital Partners GP L.L.C.1,900,000$6.19M0.0%+5.6%3.067%
2/14/2022Altium Capital Management LP1,160,000$3.78M1.0%-8.8%1.873%
2/14/2022GSA Capital Partners LLP242,132$789K0.1%+119.4%0.391%
2/14/2022Ally Bridge Group NY LLC3,539,895$11.54M4.0%+2.9%5.714%
2/11/2022Ensign Peak Advisors Inc45,000$147K0.0%-55.0%0.073%
2/10/2022Connor Clark & Lunn Investment Management Ltd.118,632$387K0.0%+14.8%0.192%
2/7/2022SG Americas Securities LLC12,012$39K0.0%-61.4%0.019%
2/3/2022ACT Capital Management LLC21,500$70K0.1%-59.0%0.035%
1/14/2022LGT Capital Partners LTD.500,000$1.63M0.0%+1,052.4%0.807%
11/17/2021Altium Capital Management LP1,272,412$5.69M1.3%+18.2%2.054%
11/16/2021Two Sigma Advisers LP172,700$772K0.0%-32.6%0.279%
11/16/2021Two Sigma Investments LP91,278$408K0.0%-24.2%0.147%
11/16/2021Metropolitan Life Insurance Co NY16,415$73K0.0%N/A0.026%
11/15/2021Point72 Hong Kong Ltd7,062$32K0.0%+168.8%0.011%
11/15/2021Cubist Systematic Strategies LLC86,990$389K0.0%-66.3%0.140%
11/15/2021Marshall Wace LLP183,451$820K0.0%-38.1%0.296%
11/15/2021Franklin Resources Inc.64,000$286K0.0%N/A0.103%
11/15/2021GSA Capital Partners LLP110,337$493K0.1%-21.7%0.178%
11/12/2021Trexquant Investment LP30,162$135K0.0%-10.4%0.049%
11/12/2021Geode Capital Management LLC857,646$3.83M0.0%-11.3%1.384%
11/12/2021Artal Group S.A.2,000,000$8.94M0.2%+17.6%3.229%
11/12/2021Connor Clark & Lunn Investment Management Ltd.103,307$462K0.0%+35.8%0.167%
11/10/2021Goldman Sachs Group Inc.490,501$2.19M0.0%-2.1%0.792%
11/10/2021Citigroup Inc.9,702$43K0.0%+49.5%0.016%
11/9/2021Barclays PLC44,863$200K0.0%-23.7%0.072%
11/9/2021BlackRock Inc.4,353,672$19.46M0.0%-2.5%7.030%
11/9/2021Ieq Capital LLC27,800$124K0.0%N/A0.045%
11/8/2021Summit Global Investments31,800$142K0.0%N/A0.051%
11/8/2021State Board of Administration of Florida Retirement System78,535$351K0.0%+233.0%0.127%
11/8/2021Russell Investments Group Ltd.10,289$45K0.0%-49.4%0.017%
11/8/2021Los Angeles Capital Management LLC258,938$1.16M0.0%-4.6%0.418%
11/4/2021Deutsche Bank AG59,973$268K0.0%+65.9%0.097%
11/1/2021SG Americas Securities LLC31,096$139K0.0%N/A0.050%
10/19/2021Assenagon Asset Management S.A.87,073$389K0.0%-24.8%0.141%
10/13/2021LGT Capital Partners LTD.43,388$194K0.0%N/A0.070%
9/3/2021Parametric Portfolio Associates LLC19,110$104K0.0%N/A0.031%
8/25/2021Marshall Wace LLP296,405$1.62M0.0%N/A0.479%
8/17/2021Millennium Management LLC557,713$3.04M0.0%+230.4%0.901%
8/17/2021Caas Capital Management LP13,905$76K0.0%N/A0.022%
8/16/2021PDT Partners LLC116,801$637K0.0%-20.8%0.189%
8/16/2021Cubist Systematic Strategies LLC257,997$1.41M0.0%+891.3%0.417%
8/16/2021Redmile Group LLC38,912$212K0.0%-81.7%0.063%
8/16/2021California State Teachers Retirement System79,478$433K0.0%+11.7%0.128%
8/16/2021Charles Schwab Investment Management Inc.391,798$2.14M0.0%+7.9%0.633%
8/16/2021State Street Corp999,254$5.45M0.0%+25.6%1.613%
8/16/2021Nuveen Asset Management LLC180,514$984K0.0%+23.1%0.291%
8/16/2021Omega Fund Management LLC2,274,831$12.40M2.1%+45.6%3.673%
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8/16/2021Goldman Sachs Group Inc.501,221$2.73M0.0%-21.3%0.809%
8/16/2021Marshall Wace LLP296,405$1.62M0.0%N/A0.479%
8/13/2021Northern Trust Corp554,422$3.02M0.0%+6.6%0.895%
8/13/2021Altium Capital Management LP1,076,942$5.87M1.4%+750.0%1.739%
8/13/2021LPL Financial LLC38,090$208K0.0%+97.1%0.062%
8/13/2021Qube Research & Technologies Ltd78,774$429K0.0%+115.9%0.127%
8/13/2021Geode Capital Management LLC966,448$5.27M0.0%+16.0%1.561%
8/13/2021Vanguard Group Inc.2,775,576$15.13M0.0%+1.6%4.482%
8/13/2021FMR LLC9,047,965$49.31M0.0%+0.4%14.610%
8/13/2021ProShare Advisors LLC26,050$142K0.0%+23.3%0.042%
(Data available from 1/1/2016 forward)

SYRS Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of SYRS shares?

During the previous two years, 19 institutional investors and hedge funds held shares of Syros Pharmaceuticals. The most heavily invested institutionals were Bain Capital Life Sciences Investors LLC ($21.42M), Avidity Partners Management LP ($13.04M), Flagship Pioneering Inc. ($10.08M), CHI Advisors LLC ($5.12M), Vanguard Group Inc. ($4.97M), Opaleye Management Inc. ($4.21M), and Kennedy Capital Management LLC ($2.17M).Learn more on Syros Pharmaceuticals' institutional investors.

What percentage of Syros Pharmaceuticals' stock is owned by institutional investors?

91.47% of Syros Pharmaceuticals' stock is owned by institutional investors. Learn more on SYRS's institutional investor holdings.

Which institutional investors have been buying Syros Pharmaceuticals' stock?

Of the 16 institutional investors that purchased Syros Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Opaleye Management Inc. ($787.55K), Bain Capital Life Sciences Investors LLC ($625.11K), CHI Advisors LLC ($531.91K), Kennedy Capital Management LLC ($404.91K), Flagship Pioneering Inc. ($300K), Avidity Partners Management LP ($209.50K), and Vanguard Group Inc. ($163.23K).

How much institutional buying is happening at Syros Pharmaceuticals?

Institutional investors have bought a total of 301,665 shares in the last 24 months. This purchase volume represents approximately $557.93K in transactions.

Which of Syros Pharmaceuticals' major shareholders have been selling company stock?

The following institutional investors have sold Syros Pharmaceuticals stock in the last 24 months: Walleye Capital LLC ($199.16K), Assenagon Asset Management S.A. ($154.13K), and Renaissance Technologies LLC ($2.40K).

How much institutional selling is happening at Syros Pharmaceuticals?

Institutional investors have sold a total of 355,688 shares in the last 24 months. This volume of shares sold represents approximately $1.24M in transactions.


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This page (NASDAQ:SYRS) was last updated on 7/10/2025 by MarketBeat.com Staff
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