Syros Pharmaceuticals (SYRS) Short Interest Ratio & Short Volume $0.0011 0.00 (0.00%) As of 09:30 AM Eastern Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock Syros Pharmaceuticals Short Interest DataSyros Pharmaceuticals (SYRS) has a short interest of 108,500 shares. This marks a -9.13% decrease in short interest from the previous month. The short interest ratio (days to cover) is 0.5, indicating that it would take 0.5 days of the average trading volume of 196,865 shares to cover all short positions.Current Short Interest108,500 sharesPrevious Short Interest119,400 sharesChange Vs. Previous Month-9.13%Dollar Volume Sold Short$282.10Short Interest Ratio0.5 Days to CoverLast Record DateJuly 15, 2025Outstanding Shares26,832,000 sharesPercentage of Shares Shorted0.40%Today's Trading Volume1,174 sharesAverage Trading Volume196,865 sharesToday's Volume Vs. Average1% Short Selling Syros Pharmaceuticals? Sign up to receive the latest short interest report for Syros Pharmaceuticals and its competitors with MarketBeat's FREE newsletter. Email Address Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartSYRS Short Interest Over TimeSYRS Days to Cover Over TimeSYRS Percentage of Float Shorted Over Time Syros Pharmaceuticals Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 7/15/2025108,500 shares $282.10 -9.1%N/A0.5 $0.00 6/30/2025119,400 shares $2.65 thousand -1.0%0.5%0.4 $0.02 6/15/2025120,600 shares $2.69 thousand -6.7%0.5%0.5 $0.02 5/31/2025129,200 shares $3.48 thousand No Change0.5%0.4 $0.03 5/15/2025129,200 shares $4.07 thousand -60.7%N/A0.4 $0.03 4/30/2025329,100 shares $10.00 thousand -41.6%N/A0.8 $0.03 4/15/2025563,700 shares $14.09 thousand -3.7%N/A1 $0.03 3/15/20254,190,000 shares $387.16 thousand +345.9%17.7%0.2 $0.09 2/28/2025939,600 shares $134.55 thousand +2.9%4.0%0.1 $0.14 2/15/2025913,100 shares $168.92 thousand +26.3%3.9%0.4 $0.19 Get the Latest News and Ratings for SYRS and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Syros Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. 1/31/2025723,200 shares $126.70 thousand -47.2%4.2%0.1 $0.18 1/15/20251,370,000 shares $326.20 thousand +24.6%7.9%0.1 $0.24 12/31/20241,100,000 shares $252.78 thousand -29.9%6.3%0.1 $0.23 12/15/20241,570,000 shares $325.30 thousand -29.6%9.0%0.2 $0.21 11/30/20242,230,000 shares $605.45 thousand -53.3%12.8%0.3 $0.27 11/15/20244,770,000 shares $1.24 million +281.6%27.7%0.6 $0.26 10/31/20241,250,000 shares $3.15 million +31.2%6.4%2.8 $2.52 10/15/2024952,600 shares $1.90 million -4.7%4.8%2.5 $1.99 9/30/2024999,900 shares $2.15 million -9.1%5.1%3.1 $2.15 9/15/20241,100,000 shares $2.15 million +14.9%5.6%3.6 $1.95 8/31/2024957,500 shares $1.57 million -22.8%4.8%4 $1.64 8/15/20241,240,000 shares $1.90 million -6.8%6.2%5.3 $1.53 7/31/20241,330,000 shares $7.98 million +4.7%6.7%12.9 $6.00 7/15/20241,270,000 shares $7.80 million -3.1%6.4%12.5 $6.14 6/30/20241,310,000 shares $6.76 million +4.0%6.6%9.8 $5.16 6/15/20241,260,000 shares $7.56 million -4.6%6.4%7.8 $6.00 5/31/20241,320,000 shares $6.73 million -13.2%6.6%8 $5.10 5/15/20241,520,000 shares $8.38 million +4.8%7.6%8 $5.51 4/30/20241,450,000 shares $7.83 million -22.0%7.8%7.4 $5.40 4/15/20241,860,000 shares $9.95 million +2.2%10.1%8.5 $5.35 3/31/20241,820,000 shares $9.74 million +4.6%9.9%8.4 $5.35 3/15/20241,740,000 shares $10.46 million +31.8%9.6%8.2 $6.01 2/29/20241,320,000 shares $9.58 million +29.4%7.3%4.1 $7.26 2/15/20241,020,000 shares $7.22 million +38.1%5.6%3.4 $7.08 1/31/2024738,800 shares $5.28 million +27.1%3.6%2.6 $7.14 1/15/2024581,200 shares $4.21 million +18.5%2.8%2.2 $7.24 12/31/2023490,600 shares $3.82 million -2.6%2.5%2.1 $7.79 12/15/2023503,500 shares $2.09 million +2.1%2.5%2.5 $4.16 11/30/2023493,400 shares $1.36 million +0.3%3.0%3.2 $2.75 11/15/2023491,800 shares $1.50 million -11.1%3.0%8.5 $3.04Is Elon's empire crumbling? 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Click here to see the Tesla shock that could blindside everyone. 10/31/2023553,100 shares $1.38 million -9.5%3.4%9.3 $2.49 10/15/2023611,200 shares $1.58 million -5.6%3.8%10.5 $2.59 9/30/2023647,300 shares $2.56 million +8.7%4.0%10.7 $3.95 9/15/2023595,500 shares $2.34 million -4.2%3.7%9.7 $3.93 8/31/2023621,800 shares $2.43 million -0.1%3.8%9.9 $3.90 8/15/2023622,600 shares $2.37 million -6.4%3.8%9.3 $3.81 7/31/2023665,000 shares $2.65 million +0.8%3.6%9 $3.98 7/15/2023660,000 shares $2.21 million +2.9%3.6%8.5 $3.35 6/30/2023641,500 shares $2.02 million +1.9%3.5%8.2 $3.15 6/15/2023629,700 shares $2.04 million +0.6%3.5%7.7 $3.24 5/31/2023625,800 shares $2.41 million -0.7%4.0%6.2 $3.85 5/15/2023630,200 shares $2.37 million -4.9%4.0%5.8 $3.76 4/30/2023662,700 shares $2.11 million -6.2%4.4%6.3 $3.18 4/15/2023706,700 shares $1.91 million -2.4%4.7%5.5 $2.70 3/31/2023724,200 shares $1.93 million +11.5%4.8%5.5 $2.67 3/15/2023649,500 shares $2.01 million +21.6%4.3%4.9 $3.09 2/28/2023534,300 shares $2.01 million -5.9%3.6%4.4 $3.76 2/15/2023567,600 shares $2.35 million -7.7%3.8%4.8 $4.14 1/31/2023615,100 shares $3.14 million +5.2%3.8%4.9 $5.11 1/15/2023584,700 shares $2.79 million -39.4%3.7%5.4 $4.77 12/30/2022964,400 shares $3.46 million +1.9%6.0%8.3 $3.59 12/15/2022946,500 shares $3.43 million +13.2%5.9%7.6 $3.62 11/30/2022836,400 shares $3.31 million +1.6%5.2%3.3 $3.96 11/15/2022823,300 shares $3.30 million +21.8%5.1%3.4 $4.01 10/31/2022676,000 shares $3.39 million +11.1%3.4%2.9 $5.02 10/15/2022608,700 shares $3.51 million -13.7%3.1%2.6 $5.77 9/30/2022705,200 shares $4.54 million -9.1%8.9%3.2 $6.44 9/15/2022775,700 shares $5.66 million -79.9%12.6%3.6 $7.29 8/31/20223,850,000 shares $3.08 million +5.2%14.3%5.3 $0.80 8/15/20223,660,000 shares $3.70 million +78.5%13.6%4.5 $1.01 7/31/20222,050,000 shares $1.61 million No Change7.6%2.4 $0.79 7/15/20222,050,000 shares $1.92 million +31.4%7.6%2.4 $0.94 6/30/20221,560,000 shares $1.50 million -53.3%3.5%1.7 $0.96 6/15/20223,340,000 shares $3.57 million -4.8%7.5%3.3 $1.07 5/31/20223,510,000 shares $2.89 million -14.8%8.0%3.9 $0.82 5/15/20224,120,000 shares $3.70 million +9.6%9.4%5 $0.90 4/30/20223,760,000 shares $3.17 million +29.7%9.0%4.9 $0.84 4/15/20222,900,000 shares $2.63 million -9.4%7.0%3.9 $0.91 3/31/20223,200,000 shares $3.81 million -4.8%7.8%5.4 $1.19 3/15/20223,360,000 shares $3.73 million -18.8%8.2%7 $1.11 2/28/20224,140,000 shares $5.34 million +1.7%10.1%9.3 $1.29 2/15/20224,070,000 shares $6.47 million -4.7%9.9%9.4 $1.59 1/31/20224,270,000 shares $8.45 million +4.4%10.9%10 $1.98 1/15/20224,090,000 shares $11.00 million +19.6%10.5%11.6 $2.69 12/31/20213,420,000 shares $11.15 million No Change8.8%10.2 $3.26 12/15/20213,420,000 shares $11.97 million -7.6%8.8%9.4 $3.50 11/30/20213,700,000 shares $14.65 million +3.6%9.5%8.2 $3.96 11/15/20213,570,000 shares $15.21 million -7.0%9.2%7.6 $4.26 10/29/20213,840,000 shares $15.86 million -6.8%9.8%8.1 $4.13 10/15/20214,120,000 shares $18.66 million +1.7%10.5%8.1 $4.53Is Elon's empire crumbling? 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Click here to see the Tesla shock that could blindside everyone. 9/30/20214,050,000 shares $18.10 million -6.0%10.3%7 $4.47 9/15/20214,310,000 shares $22.58 million -2.9%11.0%6.5 $5.24 8/31/20214,440,000 shares $23.53 million No Change11.3%6 $5.30 8/13/20214,440,000 shares $20.34 million +2.1%11.3%3.6 $4.58 7/30/20214,350,000 shares $20.10 million +9.9%10.8%3.2 $4.62 7/15/20213,960,000 shares $18.14 million -17.2%9.4%2.9 $4.58 6/30/20214,780,000 shares $26.05 million -2.3%11.4%3.5 $5.45 6/15/20214,890,000 shares $28.07 million -14.4%11.7%3.6 $5.74 5/28/20215,710,000 shares $36.83 million -6.6%13.7%4.6 $6.45 5/14/20216,110,000 shares $31.10 million +15.7%14.6%6.8 $5.09 4/30/20215,280,000 shares $32.95 million +7.8%12.5%7.4 $6.24 4/15/20214,900,000 shares $32.49 million -9.4%11.6%6.9 $6.63 3/31/20215,410,000 shares $39.20 million +10.9%12.8%7.1 $7.25 3/15/20214,880,000 shares $43.82 million +21.1%11.6%6.2 $8.98 2/26/20214,030,000 shares $35.79 million +10.7%9.6%5 $8.88 2/12/20213,640,000 shares $42.77 million -4.0%8.7%4.9 $11.75 1/29/20213,790,000 shares $40.36 million +7.7%N/A5.4 $10.65 1/15/20213,520,000 shares $48.68 million No ChangeN/A4.9 $13.83 12/31/20203,520,000 shares $41.78 million -22.8%8.8%5.6 $11.87 12/15/20204,560,000 shares $53.12 million +2.0%14.0%7.8 $11.65 11/30/20204,470,000 shares $36.43 million -3.7%11.3%8.8 $8.15 11/15/20204,640,000 shares $40.74 million -20.6%11.7%10 $8.78 10/30/20205,840,000 shares $40.18 million +4.1%14.7%12 $6.88 10/15/20205,610,000 shares $50.01 million +15.7%14.2%13.5 $8.92 9/30/20204,850,000 shares $42.87 million +31.1%12.2%13 $8.84 9/15/20203,700,000 shares $38.48 million +2.2%9.3%9.9 $10.40 8/31/20203,620,000 shares $47.97 million +31.2%9.1%9.9 $13.25 8/14/20202,760,000 shares $32.87 million -4.8%7.0%7.9 $11.91 SYRS Short Interest - Frequently Asked Questions What is Syros Pharmaceuticals' current short interest? Short interest is the volume of Syros Pharmaceuticals shares that have been sold short but have not yet been closed out or covered. As of July 15th, investors have sold 108,500 shares of SYRS short. Learn More on Syros Pharmaceuticals' current short interest. Which institutional investors are shorting Syros Pharmaceuticals? As of the most recent reporting period, the following institutional investors, funds, and major shareholders have reported short positions of Syros Pharmaceuticals: FNY Investment Advisers LLC. These positions are disclosed in Form 13F filings with the Securities and Exchange Commission. Is Syros Pharmaceuticals' short interest increasing or decreasing? Syros Pharmaceuticals saw a drop in short interest in July. As of July 15th, there was short interest totaling 108,500 shares, a drop of 9.1% from the previous total of 119,400 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. How does Syros Pharmaceuticals' short interest compare to its competitors? Here is how the short interest of companies in the industry of "pharmaceutical products" compare to Syros Pharmaceuticals: Smart for Life, Inc. (0.01%), Navidea Biopharmaceuticals, Inc. (0.00%), Virpax Pharmaceuticals, Inc. (1.24%), Scopus BioPharma Inc. (0.02%), Evelo Biosciences, Inc. (0.04%), Comera Life Sciences Holdings, Inc. (0.01%), Genocea Biosciences, Inc. (0.33%), Aridis Pharmaceuticals, Inc. (0.04%), Statera Biopharma, Inc. (0.15%), Ampio Pharmaceuticals, Inc. (0.01%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: Coinbase Global, Inc. ($5.11 billion), Charter Communications, Inc. ($4.76 billion), Reddit Inc. ($2.84 billion), SoFi Technologies, Inc. ($2.79 billion), Seagate Technology Holdings PLC ($2.79 billion), Live Nation Entertainment, Inc. ($2.67 billion), Rocket Lab Corporation ($2.49 billion), AST SpaceMobile, Inc. ($2.12 billion), Moderna, Inc. ($2.09 billion), and Omnicom Group Inc. ($2.04 billion). View all of the most shorted stocks. What does it mean to sell short Syros Pharmaceuticals stock? Short selling SYRS is an investing strategy that aims to generate trading profit from Syros Pharmaceuticals as its price is falling. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against Syros Pharmaceuticals? A short squeeze for Syros Pharmaceuticals occurs when it has a large amount of short interest and its stock appreciates in price. This forces short sellers to cover their short interest positions by buying actual shares of SYRS, which in turn drives the price of the stock up even further. How often is Syros Pharmaceuticals' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including SYRS, twice per month. The most recent reporting period available is July, 15 2025. 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