Twist Bioscience (TWST) Short Interest Ratio & Short Volume $35.99 +0.91 (+2.59%) Closing price 07/25/2025 04:00 PM EasternExtended Trading$36.02 +0.03 (+0.08%) As of 07/25/2025 07:37 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock Twist Bioscience Short Interest DataTwist Bioscience (TWST) has a short interest of 27,300 shares, representing 0.05% of the float (the number of shares available for trading by the public). This marks a -99.74% decrease in short interest from the previous month. The short interest ratio (days to cover) is 0.9, indicating that it would take 0.9 days of the average trading volume of 861,751 shares to cover all short positions.Current Short Interest27,300 sharesPrevious Short Interest10,310,000 sharesChange Vs. Previous Month-99.74%Dollar Volume Sold Short$1.00 millionShort Interest Ratio0.9 Days to CoverLast Record DateJune 30, 2025Outstanding Shares59,920,000 sharesShort Percent of Float0.05%Today's Trading Volume871,922 sharesAverage Trading Volume861,751 sharesToday's Volume Vs. Average101% Short Selling Twist Bioscience? Sign up to receive the latest short interest report for Twist Bioscience and its competitors with MarketBeat's FREE newsletter. Email Address Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartTWST Short Interest Over TimeTWST Days to Cover Over TimeTWST Percentage of Float Shorted Over Time Twist Bioscience Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 6/30/202527,300 shares $1.00 million -99.7%0.0%0.9 $36.79 6/15/202510,310,000 shares $345.59 million -3.5%17.7%8.5 $33.52 5/31/202510,680,000 shares $315.27 million +0.6%18.5%8.7 $29.52 5/15/202510,620,000 shares $319.66 million +6.6%18.4%8.7 $30.10 4/30/20259,960,000 shares $381.67 million +2.4%N/A8.2 $38.32 4/15/20259,730,000 shares $384.34 million +1.5%16.8%8.5 $39.50 3/31/20259,590,000 shares $376.50 million +8.6%16.6%8.9 $39.26 3/15/20258,830,000 shares $352.85 million -5.1%15.3%9.2 $39.96 2/28/20259,300,000 shares $361.03 million +0.9%16.1%9.9 $38.82 2/15/20259,220,000 shares $438.78 million +6.7%15.9%10.9 $47.59 Get the Latest News and Ratings for TWST and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Twist Bioscience and its competitors with MarketBeat's FREE daily newsletter. 1/31/20258,640,000 shares $452.48 million -5.9%N/A9.9 $52.37 1/15/20259,180,000 shares $417.51 million +5.5%N/A11.5 $45.48 12/31/20248,700,000 shares $404.29 million -2.8%N/A11.3 $46.47 12/15/20248,950,000 shares $425.13 million -7.3%N/A11.7 $47.50 11/30/20249,650,000 shares $474.59 million +10.3%N/A12.8 $49.18 11/15/20248,750,000 shares $322.79 million -3.0%N/A11.4 $36.89 10/31/20249,020,000 shares $364.05 million +2.2%N/A13.3 $40.36 10/15/20248,830,000 shares $408.92 million +1.5%N/A11 $46.31 9/30/20248,700,000 shares $393.07 million -2.7%N/A10.1 $45.18 9/15/20248,940,000 shares $419.73 million -4.7%N/A9.5 $46.95 8/31/20249,380,000 shares $405.59 million +1.9%N/A9.3 $43.24 8/15/20249,210,000 shares $414.45 million -6.7%N/A8.6 $45.00 7/31/20249,870,000 shares $550.84 million +3.6%N/A8.8 $55.81 7/15/20249,530,000 shares $535.11 million -0.4%N/A8.2 $56.15 6/30/20249,570,000 shares $471.61 million -11.8%N/A8.5 $49.28 6/15/202410,847,300 shares $540.63 million -2.2%N/A10 $49.84 5/31/202411,090,000 shares $464.67 million +3.6%N/A11 $41.90 5/15/202410,700,000 shares $517.45 million -10.3%N/A11.4 $48.36 4/30/202411,930,000 shares $372.57 million -2.6%N/A12.4 $31.23 4/15/202412,250,000 shares $358.19 million -0.1%N/A13.7 $29.24 3/31/202412,260,000 shares $420.64 million +2.1%N/A13.5 $34.31 3/15/202412,010,000 shares $404.02 million -3.2%N/A12.4 $33.64 2/29/202412,400,000 shares $487.20 million +0.3%N/A10.3 $39.29 2/15/202412,360,000 shares $512.94 million +0.2%N/A10 $41.50 1/31/202412,330,000 shares $399.49 million -1.8%N/A9.6 $32.40 1/15/202412,560,000 shares $453.67 million +8.1%N/A10.1 $36.12 12/31/202311,620,000 shares $428.31 million -19.8%N/A0 $36.86 12/15/202314,490,000 shares $501.50 million -6.0%N/A12 $34.61 11/30/202315,410,000 shares $370.61 million +2.6%N/A15 $24.05 11/15/202315,020,000 shares $298.90 million +0.4%N/A15.2 $19.90I warned you about Nvidia… now look what’s happening (Ad)Nvidia just got Trump’s greenlight to sell high-powered AI chips to China — and their stock surged 5% before the open. That’s the kind of move Tim Sykes built his XGPT system to trade. It scans AI news in real time, filters the noise, and pinpoints when to strike. He’s now showing exactly how it works — before the next headline hits.Watch how Tim Sykes trades AI headlines for real gains 10/31/202314,960,000 shares $235.77 million -2.9%N/A16.3 $15.76 10/15/202315,410,000 shares $261.66 million +12.6%N/A15.7 $16.98 9/30/202313,690,000 shares $277.36 million -2.1%N/A13.2 $20.26 9/15/202313,980,000 shares $292.88 million -1.4%N/A13.1 $20.95 8/31/202314,180,000 shares $311.82 million +3.7%N/A12.8 $21.99 8/15/202313,680,000 shares $292.20 million +1.9%N/A11.4 $21.36 7/31/202313,420,000 shares $326.64 million -6.4%N/A10.7 $24.34 7/15/202314,330,000 shares $333.89 million -3.0%N/A10.9 $23.30 6/30/202314,780,000 shares $302.40 million +0.9%N/A11.2 $20.46 6/15/202314,650,000 shares $272.64 million -0.3%N/A10.8 $18.61 5/31/202314,700,000 shares $222.71 million +6.3%N/A10.3 $15.15 5/15/202313,830,000 shares $186.43 million +11.8%N/A9.9 $13.48 4/30/202312,370,000 shares $154.38 million +2.3%N/A8.9 $12.48 4/15/202312,090,000 shares $168.90 million +1.4%N/A9.1 $13.97 3/31/202311,920,000 shares $179.75 million +7.8%N/A9.2 $15.08 3/15/202311,060,000 shares $187.36 million +10.5%N/A9.4 $16.94 2/28/202310,010,000 shares $194.79 million +6.0%N/A8.9 $19.46 2/15/20239,440,000 shares $227.79 million +2.9%N/A8.3 $24.13 1/31/20239,170,000 shares $263.09 million +1.0%N/A6.9 $28.69 1/15/20239,080,000 shares $235.72 million +3.9%N/A7.5 $25.96 12/30/20228,740,000 shares $208.10 million +6.6%N/A7.2 $23.81 12/15/20228,200,000 shares $208.12 million +3.8%N/A6.7 $25.38 11/30/20227,900,000 shares $216.07 million +29.9%N/A6.8 $27.35 11/15/20226,080,000 shares $185.01 million -0.2%N/A5.2 $30.43 10/31/20226,090,000 shares $199.93 million +7.4%N/A6.8 $32.83 10/15/20225,670,000 shares $162.39 million -1.2%N/A6 $28.64 9/30/20225,740,000 shares $202.28 million -8.0%N/A5.8 $35.24 9/15/20226,240,000 shares $252.28 million +4.4%N/A6.1 $40.43 8/31/20225,980,000 shares $239.92 million +5.8%N/A5.5 $40.12 8/15/20225,650,000 shares $304.59 million -6.9%N/A4.9 $53.91 7/31/20226,070,000 shares $265.50 million -8.9%N/A4.8 $43.74 7/15/20226,660,000 shares $283.05 million +4.4%N/A5.3 $42.50 6/30/20226,380,000 shares $223.04 million +1.9%N/A5.5 $34.96 6/15/20226,260,000 shares $187.36 million +1.3%N/A5.4 $29.93 5/31/20226,180,000 shares $210.37 million -26.0%N/A5.9 $34.04 5/15/20228,350,000 shares $286.32 million +14.2%N/A8.7 $34.29 4/30/20227,310,000 shares $210.82 million +8.6%N/A7.9 $28.84 4/15/20226,730,000 shares $286.63 million +5.0%N/A7.4 $42.59 3/31/20226,410,000 shares $316.53 million +4.2%N/A6.8 $49.38 3/15/20226,150,000 shares $248.52 million +3.4%N/A6.8 $40.41 2/28/20225,950,000 shares $332.84 million +9.8%N/A6.7 $55.94 2/15/20225,420,000 shares $323.85 million -0.6%N/A6.1 $59.75 1/31/20225,450,000 shares $323.84 million +9.4%11.9%6.9 $59.42 1/15/20224,980,000 shares $297.90 million +1.8%10.9%7.3 $59.82 12/31/20214,890,000 shares $378.44 million -0.6%10.7%8.4 $77.39 12/15/20214,920,000 shares $439.90 million +22.1%11.0%8.9 $89.41 11/30/20214,030,000 shares $384.87 million +27.5%9.0%8.2 $95.50 11/15/20213,160,000 shares $350.98 million -7.1%7.1%7.1 $111.07 10/29/20213,400,000 shares $403.92 million -8.1%7.7%8.4 $118.80 10/15/20213,700,000 shares $417.36 million +10.8%8.4%8.7 $112.80I warned you about Nvidia… now look what’s happening (Ad)Nvidia just got Trump’s greenlight to sell high-powered AI chips to China — and their stock surged 5% before the open. That’s the kind of move Tim Sykes built his XGPT system to trade. It scans AI news in real time, filters the noise, and pinpoints when to strike. He’s now showing exactly how it works — before the next headline hits.Watch how Tim Sykes trades AI headlines for real gains 9/30/20213,340,000 shares $357.28 million -0.9%7.5%7.9 $106.97 9/15/20213,370,000 shares $380.64 million -1.5%7.6%7.8 $112.95 8/31/20213,420,000 shares $387.18 million +0.9%7.7%7.4 $113.21 8/13/20213,390,000 shares $340.73 million +8.3%7.7%7.1 $100.51 7/30/20213,130,000 shares $0.00 No Change7.3%5.8 $0.00 7/15/20213,130,000 shares $353.47 million -4.3%7.3%5.3 $112.93 6/30/20213,270,000 shares $435.73 million -10.4%7.7%5.3 $133.25 6/15/20213,650,000 shares $396.65 million -1.1%8.6%5 $108.67 5/28/20213,690,000 shares $395.97 million -6.6%8.6%4.6 $107.31 5/14/20213,950,000 shares $348.11 million +12.5%N/A4.3 $88.13 4/30/20213,510,000 shares $479.40 million -6.7%N/A3.6 $136.58 4/15/20213,760,000 shares $534.03 million -8.1%N/A3.8 $142.03 3/31/20214,090,000 shares $448.71 million +14.3%N/A4 $109.71 3/15/20213,580,000 shares $506.21 million +39.8%N/A3.6 $141.40 2/26/20212,560,000 shares $344.17 million +28.0%N/A2.7 $134.44 2/12/20212,000,000 shares $330.81 million +8.7%N/A2.3 $165.41 1/29/20211,840,000 shares $312.30 million -22.7%N/A2.4 $169.73 1/15/20212,380,000 shares $450.84 million -5.2%N/A3.4 $189.43 12/31/20202,510,000 shares $369.35 million -14.0%N/A3.8 $147.15 12/15/20202,920,000 shares $409.54 million -20.0%N/A4.5 $140.26 11/30/20203,650,000 shares $418.55 million -10.1%N/A5.9 $114.67 11/15/20204,060,000 shares $435.88 million +2.3%N/A7.2 $107.36 10/30/20203,970,000 shares $315.06 million -7.2%N/A7 $79.36 10/15/20204,280,000 shares $386.06 million -1.6%13.3%7.4 $90.20 9/30/20204,350,000 shares $330.47 million -1.6%13.5%7.8 $75.97 9/15/20204,420,000 shares $272.80 million +5.2%13.7%8.2 $61.72 8/31/20204,200,000 shares $293.71 million -12.5%13.1%8.1 $69.93 8/14/20204,800,000 shares $318.24 million -0.2%14.9%8.4 $66.30 7/31/20204,810,000 shares $269.55 million -2.0%15.1%8.8 $56.04 TWST Short Interest - Frequently Asked Questions What is Twist Bioscience's current short interest? Short interest is the volume of Twist Bioscience shares that have been sold short but have not yet been covered or closed out. As of June 30th, traders have sold 27,300 shares of TWST short. 0.05% of Twist Bioscience's shares are currently sold short. Learn More on Twist Bioscience's current short interest. What is a good short interest ratio for Twist Bioscience? The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. TWST shares currently have a short interest ratio of 1.0. Learn More on Twist Bioscience's short interest ratio. Which institutional investors are shorting Twist Bioscience? As of the most recent reporting period, the following institutional investors, funds, and major shareholders have reported short positions of Twist Bioscience: Walleye Trading LLC, Walleye Capital LLC, and Simplex Trading LLC. These positions are disclosed in Form 13F filings with the Securities and Exchange Commission. What is a good short interest percentage for Twist Bioscience? Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 0.05% of Twist Bioscience's floating shares are currently sold short. Is Twist Bioscience's short interest increasing or decreasing? Twist Bioscience saw a drop in short interest in the month of June. As of June 30th, there was short interest totaling 27,300 shares, a drop of 99.7% from the previous total of 10,310,000 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. How does Twist Bioscience's short interest compare to its competitors? 0.05% of Twist Bioscience's shares are currently sold short. Here is how the short interest of companies compare to Twist Bioscience: Adaptive Biotechnologies Corporation (7.12%), Beam Therapeutics Inc. (24.82%), CRISPR Therapeutics AG (30.90%), 10x Genomics (1.14%), Veracyte, Inc. (7.69%), BridgeBio Pharma, Inc. (14.05%), Verona Pharma PLC American Depositary Share (0.60%), Blueprint Medicines Corporation (5.95%), Roivant Sciences Ltd. (10.24%), Elanco Animal Health Incorporated (5.08%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: SPDR S&P 500 ETF Trust ($72.10 billion), Invesco QQQ ($26.89 billion), iShares Russell 2000 ETF ($19.61 billion), MicroStrategy Incorporated ($9.52 billion), iShares 20+ Year Treasury Bond ETF ($8.70 billion), WD-40 Company ($7.66 billion), Technology Select Sector SPDR Fund ($6.10 billion), Invesco S&P 500 Equal Weight ETF ($5.80 billion), Invesco S&P 500 Top 50 ETF ($5.53 billion), and Vanguard Large-Cap ETF ($5.35 billion). View all of the most shorted stocks. What does it mean to sell short Twist Bioscience stock? Short selling TWST is an investing strategy that aims to generate trading profit from Twist Bioscience as its price is falling. TWST shares are trading up $0.91 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against Twist Bioscience? A short squeeze for Twist Bioscience occurs when it has a large amount of short interest and its stock increases in price. This forces short sellers to cover their short interest positions by buying actual shares of TWST, which in turn drives the price of the stock up even further. How often is Twist Bioscience's short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including TWST, twice per month. The most recent reporting period available is June, 30 2025. More Short Interest Resources from MarketBeat Related Companies ADPT Short Interest Data BEAM Short Interest Data CRSP Short Interest Data TXG Short Interest Data VCYT Short Interest Data BBIO Short Interest Data VRNA Short Interest Data BPMC Short Interest Data ROIV Short Interest Data ELAN Short Interest Data Short Interest Tools Stocks to Short Largest Short Interest Positions Short Interest Increases Short Interest Decreases Short Interest Reporting Dates This page (NASDAQ:TWST) was last updated on 7/26/2025 by MarketBeat.com Staff From Our PartnersCritical AI announcement set to ignite AI 2.0 I just put together an urgent new presentation that you need to see right away. In short: I believe we are...Timothy Sykes | SponsoredGoogle did what!?!?A new technology has sparked a modern-day gold rush in Silicon Valley. OpenAI’s Sam Altman invested $375M. 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