NYSE:MBX MBX Biosciences (MBX) Stock Price, News & Analysis $10.00 -0.07 (-0.70%) Closing price 09/19/2025 04:00 PM EasternExtended Trading$13.69 +3.69 (+36.94%) As of 09/19/2025 08:00 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock About MBX Biosciences Stock (NYSE:MBX) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get MBX Biosciences alerts:Sign Up Key Stats Today's Range$9.67▼$10.2850-Day Range$9.74▼$15.4952-Week Range$4.81▼$27.50Volume1.35 million shsAverage Volume338,433 shsMarket Capitalization$335.94 millionP/E RatioN/ADividend YieldN/APrice Target$37.63Consensus RatingBuy Company Overview MBX Biosciences, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of precision peptide therapies for the treatment of endocrine and metabolic disorders. Its lead product candidate is MBX 2109, a parathyroid hormone peptide prodrug, which is in Phase 2 clinical trial designed as a potential long-acting hormone replacement therapy for the treatment of chronic hypoparathyroidism. The company is also developing MBX 1416, a long-acting glucagon-like peptide-1 (GLP-1) receptor antagonist that is in Phase 1 clinical trial designed as a potential therapy for post-bariatric hypoglycemia, a chronic complication of bariatric surgery. In addition, it is developing MBX 4291, a lead obesity product candidate, which is in investigational new drug-enabling studies designed as a long-acting and highly potent GLP-1 and glucose-dependent insulinotropic polypeptide receptor co-agonist prodrug for treating obesity and co-morbidities. The company was founded in 2018 and is based in Carmel, Indiana. Read More MBX Biosciences Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks47th Percentile Overall ScoreMBX MarketRank™: MBX Biosciences scored higher than 47% of companies evaluated by MarketBeat, and ranked 573rd out of 948 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.9 / 5Analyst RatingBuy Consensus RatingMBX Biosciences has received a consensus rating of Buy. The company's average rating score is 3.00, and is based on 8 buy ratings, no hold ratings, and no sell ratings.Upside PotentialMBX Biosciences has a consensus price target of $37.63, representing about 276.3% upside from its current price of $10.00.Amount of Analyst CoverageMBX Biosciences has only been the subject of 2 research reports in the past 90 days.Read more about MBX Biosciences' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for MBX Biosciences are expected to grow in the coming year, from ($13.25) to ($2.30) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of MBX Biosciences is -2.20, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of MBX Biosciences is -2.20, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings. Short InterestN/AShort Interest LevelN/A Short InterestThere is no current short interest data available for MBX. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldMBX Biosciences does not currently pay a dividend.Dividend GrowthMBX Biosciences does not have a long track record of dividend growth. Sustainability and ESGN/AEnvironmental ScoreN/A Short InterestThere is no current short interest data available for MBX. News and Social Media2.0 / 5News Sentiment0.58 News SentimentMBX Biosciences has a news sentiment score of 0.58. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.78 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 3 news articles for MBX Biosciences this week, compared to 2 articles on an average week.Search InterestOnly 6 people have searched for MBX on MarketBeat in the last 30 days. This is a decrease of -14% compared to the previous 30 days.MarketBeat FollowsOnly 1 people have added MBX Biosciences to their MarketBeat watchlist in the last 30 days. This is a decrease of 0% compared to the previous 30 days. Company Ownership1.7 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, MBX Biosciences insiders have not sold or bought any company stock.Percentage Held by Insiders52.19% of the stock of MBX Biosciences is held by insiders. A high percentage of insider ownership can be a sign of company health.Read more about MBX Biosciences' insider trading history. Receive MBX Stock News and Ratings via Email Sign-up to receive the latest news and ratings for MBX Biosciences and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. MBX Stock News HeadlinesMBX Biosciences to Provide Topline Results from its Phase 2 Trial of Potential Once-Weekly Canvuparatide for Hypoparathyroidism (HP) on Monday, September 22September 19 at 4:18 PM | globenewswire.comMBX Biosciences (NYSE:MBX) & Gemini Therapeutics (NASDAQ:GMTX) Head to Head SurveySeptember 18 at 4:06 AM | americanbankingnews.comThis is the “End of Tesla” as we know it…Jeff has identified five of the past seven number-one performing tech stocks — before they took off. His Tesla call alone could have made readers 21 TIMES THEIR MONEY, if they listened to his recommendation. Don't miss his next big prediction.September 20 at 2:00 AM | Brownstone Research (Ad)Comparing MBX Biosciences (MBX) & Its RivalsSeptember 11, 2025 | americanbankingnews.comMBX Biosciences, Inc.: MBX Biosciences Doses First Participant in Phase 1 Trial of MBX 4291 for the Treatment of ObesitySeptember 6, 2025 | finanznachrichten.deMBX Biosciences doses first participant in Phase 1 trial of MBX 4291September 4, 2025 | msn.comMBX Biosciences Doses First Participant in Phase 1 Trial of MBX 4291 for the Treatment of ObesitySeptember 4, 2025 | globenewswire.comMBX Biosciences Insiders Added US$579.8k Of Stock To Their HoldingsAugust 20, 2025 | uk.finance.yahoo.comSee More Headlines MBX Stock Analysis - Frequently Asked Questions How have MBX shares performed this year? MBX Biosciences' stock was trading at $18.43 on January 1st, 2025. Since then, MBX shares have decreased by 45.7% and is now trading at $10.00. How were MBX Biosciences' earnings last quarter? MBX Biosciences, Inc. (NYSE:MBX) announced its earnings results on Thursday, November, 7th. The company reported ($2.78) earnings per share for the quarter, missing the consensus estimate of ($2.72) by $0.06. When did MBX Biosciences IPO? MBX Biosciences (MBX) raised $163 million in an IPO on Friday, September 13th 2024. The company issued 10,200,000 shares at a price of $16.00 per share. Who are MBX Biosciences' major shareholders? MBX Biosciences' top institutional investors include MPM Bioimpact LLC (3.85%), EcoR1 Capital LLC (3.42%), Franklin Resources Inc. (1.48%) and Geode Capital Management LLC (1.04%). Insiders that own company stock include Life Sciences X LP Frazier, Edward T Mathers, Carl L Gordon, P Kent Hawryluk and Ora H Pescovitz. View institutional ownership trends. How do I buy shares of MBX Biosciences? Shares of MBX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of MBX Biosciences own? Based on aggregate information from My MarketBeat watchlists, some other companies that MBX Biosciences investors own include PepsiCo (PEP), Arch Capital Group (ACGL), Adobe (ADBE), Analog Devices (ADI), Alnylam Pharmaceuticals (ALNY), Amgen (AMGN) and AstraZeneca (AZN). Company Calendar Last Earnings11/07/2024Today9/20/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNYSE SectorMedical Industry Pharmaceutical preparations Sub-IndustryPharmaceutical Products Current SymbolNYSE:MBX Previous SymbolNYSE:MBX CIK1776111 Webmbxbio.com Phone(317) 659-0200FaxN/AEmployees36Year FoundedN/APrice Target and Rating Average Price Target for MBX Biosciences$37.63 High Price Target$44.00 Low Price Target$30.00 Potential Upside/Downside+276.3%Consensus RatingBuy Rating Score (0-4)3.00 Research Coverage8 Analysts Profitability EPS (Trailing Twelve Months)N/A Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet IncomeN/A Net MarginsN/A Pretax MarginN/A Return on EquityN/A Return on AssetsN/A Debt Debt-to-Equity RatioN/A Current RatioN/A Quick RatioN/A Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book ValueN/A Price / BookN/AMiscellaneous Outstanding Shares33,594,000Free FloatN/AMarket Cap$335.94 million OptionableN/A BetaN/A Social Links Options Trading Made Easy - Download NowLearn the basics of options trading and how to use them to boost returns and manage risk with this free report from MarketBeat. Click the link below to get your free copy.Get This Free Report This page (NYSE:MBX) was last updated on 9/20/2025 by MarketBeat.com Staff From Our PartnersREVEALED: Something Big Happening Behind White House Doorswhat I just learned about what’s unfolding in the White House is truly stunning… And you need to see it for...Paradigm Press | SponsoredCrypto Gets Official Government Backing—Here's the WinnerTrump Just Signed the GENIUS Act—One Coin is About to Explode We're at the BEGINNING of smart money really ...Crypto 101 Media | SponsoredNvidia CEO Makes First Ever Tesla AnnouncementWhile headlines focus on Tesla’s car sales, tech analyst Jeff Brown says the real story is Tesla’s role in a $...Brownstone Research | SponsoredCollege grad makes $64,000 a monthA Wall Street legend just helped train our own proprietary AI system in the stock market (a project that took ...Stansberry Research | SponsoredIRS Wants Another Check on Sept 15th—What If You Could Keep It Instead?On September 15th, the IRS collects another round of quarterly tax payments—targeting self-employed profession...American Alternative | SponsoredWhat's the Best Way to Lower RMD Taxes?Turning 73 triggers a key IRS rule: you must begin taking required minimum distributions (RMDs) from certain r...SmartAsset | SponsoredThe Coin That Could Define Trump’s Crypto PresidencyWhen Trump returned to office, one of his first moves was to tap PayPal’s former COO, David Sacks, as a top ad...Weiss Ratings | SponsoredAn $8 trillion-dollar discovery 17,000 ft underwater A strange rock pulled from the ocean floor may hold the key to a $16 trillion resource boom. 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