Oncotelic Therapeutics (OTLC) Stock Price, News & Analysis

Company Overview

Oncotelic Therapeutics is a clinical‐stage biotechnology company dedicated to the development of novel oncolytic virotherapy and diagnostic platforms for cancer treatment. The company’s lead therapeutic candidate, telomelysin (OBP‐301), is an oncolytic adenovirus engineered to selectively replicate in telomerase‐positive tumor cells, offering a targeted approach to destroying cancerous tissue while sparing healthy cells. In addition to its therapeutic pipeline, Oncotelic markets TelomeScan, a proprietary diagnostic assay designed to detect and enumerate viable circulating tumor cells by exploiting telomerase activity.

Originally founded with technology licensed from Japanese research institutions, Oncotelic has established collaborative relationships in both the United States and Asia to advance its clinical and commercial programs. The company has conducted early‐phase clinical studies in solid tumors and is exploring combination strategies with immune checkpoint inhibitors. Oncotelic’s research and development efforts are focused on expanding the potential of its oncolytic platform across multiple cancer indications and optimizing its diagnostic capabilities to support personalized treatment strategies.

Headquartered in Gaithersburg, Maryland, Oncotelic operates with a lean scientific and management team. Leadership is spearheaded by President and Chief Executive Officer Bryan M. Saltjian, Ph.D., who brings extensive experience in viral immunotherapy and biotechnology commercialization. Under his guidance, Oncotelic aims to advance its pipeline through clinical milestones and strategic partnerships that can bring its oncolytic and diagnostic innovations to the broader oncology community.

Key Stats

• Today's Range: $0.09 to $0.10
• 50-Day Range: $0.04 to $0.10
• 52-Week Range: $0.02 to $0.10
• Volume: 383,775 shs
• Average Volume: 460,557 shs
• Market Capitalization: $43.69 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: N/A
• Consensus Rating: N/A

Oncotelic Therapeutics Stock Analysis - MarketRank™

Oncotelic Therapeutics scored higher than 24% of companies evaluated by MarketBeat. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: N/A
• Analyst Rating: N/A

Consensus Rating

There is not enough analysis data for Oncotelic Therapeutics.

Earnings and Valuation

• Score: 0.0 / 5
• Proj. Earnings Growth: N/A

Price to Earnings Ratio vs. the Market

The P/E ratio of Oncotelic Therapeutics is -9.95, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Oncotelic Therapeutics is -9.95, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Oncotelic Therapeutics has a P/B Ratio of 4.98. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.

Short Interest

• Score: 5.0 / 5
• Short Interest Level: Healthy

Percentage of Shares Shorted

0.00% of the outstanding shares of Oncotelic Therapeutics have been sold short.

Short Interest Ratio / Days to Cover

Oncotelic Therapeutics has a short interest ratio ("days to cover") of 0, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Oncotelic Therapeutics has recently decreased by 99.06%, indicating that investor sentiment is improving significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Oncotelic Therapeutics does not currently pay a dividend.

Dividend Growth

Oncotelic Therapeutics does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

0.00% of the outstanding shares of Oncotelic Therapeutics have been sold short.

Short Interest Ratio / Days to Cover

Oncotelic Therapeutics has a short interest ratio ("days to cover") of 0, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Oncotelic Therapeutics has recently decreased by 99.06%, indicating that investor sentiment is improving significantly.

News and Social Media

• Score: 2.8 / 5
• News Sentiment: N/A

News Sentiment

Oncotelic Therapeutics has a news sentiment score of 1.00. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.46 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 1 news article for Oncotelic Therapeutics this week, compared to 0 articles on an average week.

Company Ownership

• Score: 1.7 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, Oncotelic Therapeutics insiders have not sold or bought any company stock.

Percentage Held by Insiders

39.22% of the stock of Oncotelic Therapeutics is held by insiders. A high percentage of insider ownership can be a sign of company health.

OTLC Stock Analysis - Frequently Asked Questions

How have OTLC shares performed this year?

Oncotelic Therapeutics' stock was trading at $0.0350 at the beginning of 2025. Since then, OTLC shares have increased by 184.3% and is now trading at $0.0995.

How were Oncotelic Therapeutics' earnings last quarter?

Oncotelic Therapeutics, Inc. (OTCMKTS:OTLC) released its quarterly earnings data on Thursday, August, 19th. The company reported ($0.01) EPS for the quarter, beating the consensus estimate of ($0.03) by $0.02.

How do I buy shares of Oncotelic Therapeutics?

Shares of OTLC stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Oncotelic Therapeutics own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Oncotelic Therapeutics investors own include MariMed (MRMD), First Wave BioPharma (FWBI), DSS (DSS), Cemex (CX), CohBar (CWBR), ContraFect (CFRX) and Avid Bioservices (CDMO).

Company Calendar

• Last Earnings: 8/19/2021
• Today: 10/18/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: OTCMKTS
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: OTCMKTS:OTLC
• CIK: 908259
• Web: www.mateon.com
• Phone: (650) 635-7000
• Fax: 650-635-7001
• Employees: 20
• Year Founded: N/A

Profitability

• EPS (Trailing Twelve Months): ($0.01)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$4.52 million
• Net Margins: N/A
• Pretax Margin: N/A
• Return on Equity: -9.62%
• Return on Assets: -2.72%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 0.01
• Quick Ratio: 0.01

Sales & Book Value

• Annual Sales: $70 thousand
• Price / Sales: 624.14
• Cash Flow: $0.01 per share
• Price / Cash Flow: 17.63
• Book Value: $0.02 per share
• Price / Book: 4.98

Miscellaneous

• Outstanding Shares: 439,090,000
• Free Float: 266,879,000
• Market Cap: $43.69 million
• Optionable: Not Optionable
• Beta: -0.69