Nykode Therapeutics AS (OTCMKTS:VACBF) is a clinical-stage biotechnology company based in Oslo, Norway, focused on the development of precisely targeted immunotherapies. The company’s proprietary platform is designed to deliver antigenic payloads directly to antigen-presenting cells, with the goal of eliciting potent and durable immune responses against both cancerous and infectious disease targets. By combining modular antigen design with novel delivery modalities, Nykode aims to drive next-generation vaccine and immunotherapy solutions.
The company’s clinical pipeline includes several lead candidates in oncology and infectious diseases. The most advanced oncology program, VB10.16, is a therapeutic vaccine targeting HPV16-associated lesions and cancers, currently evaluated in multiple clinical trials. In parallel, a personalized neoantigen vaccine program, VB10.NEO, is being developed to address patient-specific tumor antigens. On the infectious disease front, Nykode is exploring prophylactic vaccine candidates designed to combat pathogens with high unmet medical need, leveraging insights from its immunomodulation platform.
Founded by immunology experts Dr. Inger Sandlie and Professor Bjarne Bogen, the company originally operated under the name Vaccibody ASA until a rebranding to Nykode Therapeutics in 2021. Since its inception, Nykode has established research collaborations and clinical trial sites across Europe and North America, reflecting its commitment to global patient impact. The company is led by a management team with extensive experience in vaccine development and biopharmaceutical commercialization, including CEO Gunn Hedlund, who has steered the organization through multiple clinical milestones and strategic partnerships.
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